Ingabe uthola amaqhubu emzimbeni wakho? Kungaba yi-Follicular Lymphoma. Ake sixoxe ngakho!

Cabanga nje, uSamantha Akka uhlala ethi ukhathele kakhulu, futhi uyajuluka ebusuku. Ngezinye izikhathi uthi futhi uthola iqhubu elincane entanyeni yakhe. Nakuba lokhu ngezinye izikhathi kungacatshangwa empilweni yethu yansuku zonke, kungaba izimpawu zesifo esifana ne-Follicular Lymphoma. Ungakhathazeki, sizokhuluma ngalokhu kalula, ngendlela ongayiqonda.

Kuyini i-Follicular Lymphoma?

Kalula nje, i-follicular lymphoma uhlobo lomdlavuza olukhula kancane kakhulu . Uma sikhuluma iqiniso, umdlavuza okhula emangqamuzaneni ethu e-lymph. Ungakhula kuma-lymph node akho - noma, njengoba siwabiza kanjalo, ama-lymph node akho - noma umnkantsha wakho, noma kwezinye izitho zangaphakathi. Into emangalisayo ukuthi abanye abantu bangaba nalesi sifo ngaphandle kokubonisa izimpawu . Yingakho odokotela besibheka njengesifo esingamahlalakhona . Izindaba ezinhle ukuthi kukhona ukwelashwa kwaso. Kodwa-ke, ngezinye izikhathi lesi sifo singabuya ngemva kokwelashwa. Kodwa odokotela bacabanga ukuthi isikhathi asikude lapho lesi sifo singelapheka ngokuphelele ngemithi emisha.

Ubani onamathuba amaningi okuthola lesi sifo?

Ngokwezibalo, cishe abantu abathathu kuya kwabane kwabayikhulu lezinkulungwane (cishe abangu-3.5) bangaba nalesi simo. Abantu abangaphezu kweminyaka engu-65 banamathuba amakhulu okuthola lesi sifo kunabantu abasebasha. Kutholakale nokuthi amadoda anamathuba amaningi okuthola lesi sifo uma kuqhathaniswa nabesifazane.

I-Follicular Lymphoma ithinta kanjani umzimba wami?

I-follicular lymphoma iwuhlobo lwe -B-cell lymphoma , uhlobo lwe- non-Hodgkin's lymphoma . Ngakho-ke, ingabonisa nezimpawu ze-non-Hodgkin's lymphoma, njengezinhlayiya ze-lymph ezivuvukele, umkhuhlane, kanye nokujuluka ebusuku .

Kodwa-ke, abantu abaningi batholakala benalesi sifo ngaphambi kokuba babe nezimpawu . Kumuntu ongenazo izimpawu futhi onempilo enhle, odokotela bangase bangaqali ukwelashwa ngokushesha. Kunalokho, bazosebenzisa isu elibizwa ngokuthi 'ukulinda ngokuqapha' noma 'ukuqapha okusebenzayo' . Lokhu kusho ukuthi odokotela bahlala beqapha impilo yakho nezimpawu zakho.

Lesi sifo singakuthinta ngokwengqondo ngaphambi kokuba sikuthinte ngokomzimba. Ucwaningo lwamuva nje lubonise ukuthi abantu abane-follicular lymphoma kanye nama-lymphoma afanayo akhula kancane bahlushwa ukukhathazeka ngokweqile ngenxa yokungaqiniseki kokuthi 'Izimpawu zizovela nini?' nokuthi 'Ukwelashwa kuzoqala nini?'

Ingabe i-Follicular Lymphoma iyisifo esibi kakhulu?

Yebo, empeleni yi-follicular lymphoma.Kungaba yisimo sezokwelapha esibalulekile nesinzima. Kunezizathu eziningana zalokhu:

• Uguquko: Ngezinye izikhathi, i-follicular lymphoma ingaguquka ibe uhlobo lomdlavuza olunamandla kakhulu olubizwa ngokuthi i-diffuse large B-cell lymphoma (DLBCL) . Lokhu kungabangela izimpawu ezintsha nezinzima kakhulu kanye nokusabalala komdlavuza kwezinye izingxenye zomzimba. Cishe amaphesenti amathathu (3%) abantu abane-follicular lymphoma bazoguquka babe yi-DLBCL. Cabanga ukuthi kunzima kangakanani ukuba nesifo esibi ngokuzumayo.
• Ukubuyela Esimeni Esijwayelekile: Enye inselele ngalesi sifo ukuthi ngemva kokwelashwa, izimpawu zingase ziphele, bese ziphinde zivuke ngemva kwesikhashana. Lo mjikelezo wokubuyela esimeni esijwayelekile wenza kube nzima ngabantu abanalesi sifo ukuthi bazizwe sengathi 'baphelile'. Ngamanye amazwi, kufanele bahlale bephila nokwesaba okuncane ezinhliziyweni zabo.

Ziyini izimpawu ze-Follicular Lymphoma?

Kunezimpawu eziningana ezivamile ezingabonakala kulesi sifo. Kodwa khumbula, ukuthi nje unalezi zimpawu akusho ukuthi unalesi sifo. Kodwa kubalulekile ukuqaphela lezi zinto.

• Ama-lymph node avuvukele entanyeni, emakhwapheni, noma endaweni yezimbotshana ngaphandle kobuhlungu. Siwabiza ngokuthi ama-lymph node avuvukele, yilokho ayikho.
• Umkhuhlane ongenalo olunye ukutheleleka noma ukugula.
• Ukwehlisa isisindo ngaphandle kwesizathu esibonakalayo. Kufanele ukhathazeke, ikakhulukazi uma ulahlekelwe yi -10% noma ngaphezulu kwesisindo somzimba wakho ezinyangeni eziyisithupha ezedlule .
• Ukujuluka nokuzizwa ubanda. Ikakhulukazi uma ujuluka kakhulu uze umanzise umbhede wakho ebusuku (ukujuluka ebusuku kumanzi) futhi kuqhubeke, kungaba uphawu lwesifo esithile.
• Ukukhathala. Lokhu akusikho ukukhathala okuvamile. Ukukhathala okukhulu okwenza kube nzima ukwenza ngisho nemisebenzi yansuku zonke eyisisekelo .

Yini ebangela i-Follicular Lymphoma?

Eqinisweni, abacwaningi abakazazi zonke izimbangela eziqondile zalesi sifo. Kodwa bathole ukuthi cishe kumaphesenti angu-85 (85%) ezimo, imbangela eyinhloko yalesi sifo izinguquko kuma-chromosome ethu . Ngenxa yalezi zinguquko, ezingavamile, noma umdlavuza, amangqamuzana aqala ukuhlukana futhi aphindaphindeke ngaphandle kokulawula.

Odokotela baxilonga kanjani i-follicular lymphoma?

Odokotela basebenzisa izivivinyo eziningana ukuze bathole ukuthi unalesi sifo noma cha.

• I-Biopsy: Lokhu kuhilela ukuthatha ingxenye encane yezicubu ku-lymph node evuvukele.Kuwukuhlolwa nge-microscope ukuze kubonakale ukuthi akhona yini amangqamuzana omdlavuza. Lena yindlela eyinhloko yokuqinisekisa lesi sifo .
• Ukuskena kwe-PET (i-Positron Emission Tomography - ukuskena kwe-PET): Lokhu kuskena kungabonisa ukuthi amangqamuzana omdlavuza asebenza kangakanani, ukuthi asakazeke kangakanani, kanye nezinga lomdlavuza.
• I-CT scan (i-Computed Tomography - i-CT scan): Lokhu kusiza odokotela ukuthi babone ukuthi umdlavuza ukuphi emzimbeni, ukuthi mkhulu kangakanani, nokuthi usabela kanjani ekwelashweni.

Yiziphi izigaba ze-Follicular Lymphoma?

Njenganoma yimuphi umdlavuza, i-follicular lymphoma inezigaba ezahlukene. Lezi zigaba zisetshenziswa odokotela ukunquma ukuthi yiluphi uhlobo lokwelashwa olungcono kakhulu. Kunezigaba ezine eziyinhloko (I kuya ku-IV):

• Isigaba I: Umdlavuza ukhona endaweni eyodwa noma ngaphezulu yama-lymph node . Cishe amaphesenti angama-25 (25%) amacala e-follicular lymphoma atholakala kulesi sigaba.
• Isigaba II: Umdlavuza utholakala ezindaweni ezimbili noma ngaphezulu ze-lymph node ngaphezulu noma ngaphansi kwe-diaphragm (umsipha ohlukanisa isifuba nesisu sethu). Cishe amaphesenti ayi-15 (15%) eziguli atholakala kulesi sigaba.
• Isigaba III: Umdlavuza usezinhlayiyeni ze-lymph ezinhlangothini zombili ze-diaphragm (ngenhla nangaphansi) . Cishe amaphesenti angama-26 (26%) eziguli atholakala kulesi sigaba.
• Isigaba IV: Umdlavuza ususakazekele ngale kwama-lymph node, wafinyelela emnkantsheni noma kwezinye izinhlelo zezitho zomzimba . Cishe amaphesenti angama-27 (27%) eziguli atholakala kulesi sigaba esithuthukile kakhulu.

Iphathwa kanjani i-Follicular Lymphoma?

Odokotela abasebenzisi ukwelashwa okufanayo kuwo wonke umuntu lapho belapha i-follicular lymphoma. Ukwelashwa kunqunywa yizici eziningi, okuhlanganisa isimo sesiguli kanye nesigaba sesifo. Ngezinye izikhathi, kusetshenziswa inhlanganisela 'yokulinda ngokuqapha' kanye nezinye izindlela zokwelapha.

• Ukulinda ngokuqaphela noma ukuqapha okusebenzayo: Uma udokotela wakho encoma le ndlela, kuzodingeka ubonane nodokotela wakho njalo, uhlolwe ngokomzimba, uhlolwe igazi, kanye nokuskena . Lokhu kusho ukulinda kuze kube yilapho kuvela izimpawu noma isifo siba sibi kakhulu.
• Ukwelashwa ngemisebe: Lolu hlobo lokwelashwa ngemisebe lungasetshenziswa ezifweni ezisesigabeni sokuqala , lapho umdlavuza utholakala endaweni eyodwa kuphela. Lusebenzisa imisebe enamandla amakhulu ukubhubhisa amangqamuzana omdlavuza.
• Ukwelashwa ngama-antibody e-monoclonal:Lokhu kuyindlela yokwelapha eyinkimbinkimbi. Kalula nje, isebenzisa uhlobo lwe-antibody olwenziwe ngokukhethekile elabhorethri . Lawa ma-antibody angathola amangqamuzana omdlavuza futhi awabhubhise.
• Ukwelashwa ngamakhemikhali: Lokhu kuyinto abantu abaningi abayizwayo lapho bekhuluma ngokwelashwa komdlavuza. Kuhilela ukusetshenziswa kwemithi ekhethekile ukubhubhisa amangqamuzana omdlavuza . Ukwelashwa ngamakhemikhali kunganikezwa kodwa noma kuhlanganiswe nezinye izindlela zokwelapha.
• Ukwelashwa okuqondiwe: Imithi esetshenziswa kulolu hlobo lokwelashwa ihlasela futhi ihlasele amangqamuzana omdlavuza kuphela, ngaphandle kokulimaza amangqamuzana aphilile avamile . Lokhu kunganciphisa imiphumela emibi.
• Ukwelashwa nge-immunotherapy: Lokhu kuyindlela yokwelapha ethakazelisa kakhulu. Isebenza ngokuvuselela amasosha omzimba wakho ukuze alwe nomdlavuza. Kungandisa ukukhiqizwa kwamangqamuzana alwa namangqamuzana omdlavuza, noma kusiza amangqamuzana anempilo ukuthi aqaphele futhi ahlasele amangqamuzana omdlavuza.
• Ukufakelwa kweseli lomnkantsha/i-stem cell: Uma i-follicular lymphoma iphinda ibuya ngemva kokwelashwa ngamakhemikhali, odokotela bangase batuse lokhu kwelashwa. Lokhu kuhilela ukufaka esikhundleni somnkantsha onesifo ngamaseli omnkantsha noma ama-stem cell aphilile.

Ingabe i-follicular lymphoma ingavinjelwa?

Ngeshwa, abacwaningi abakayitholi indlela ethile yokunciphisa ingozi yokuthola lesi sifo. Uma unemibuzo noma ukungabaza ngalokhu, into engcono kakhulu ongayenza ukubona udokotela wakho bese ukhuluma ngomlando wakho wezokwelapha kanye nomlando wezokwelapha womndeni. Ngemuva kwalokho udokotela angakunikeza iseluleko esidingekayo.

Ungaphila isikhathi esingakanani ne-Follicular Lymphoma?

Njengoba sesixoxile ngaphambili, i-follicular lymphoma iyisifo esikhula kancane kancane futhi esingamahlalakhona . Lokhu kusho ukuthi ungaphila nalesi sifo isikhathi eside. Izifundo zikhombisile ukuthi cishe ingxenye (cishe ama-50%) yabantu abatholakale benalesi sifo baphila cishe iminyaka engama-20 . Futhi, cishe ama-90% eziguli asaphila eminyakeni emihlanu ngemva kokuba lesi sifo sitholakale. Ngakho-ke lokhu kukhombisa ukuthi yize lesi kuyisifo esibulalayo, kukhona ithuba lokuphila naso.

Ngingazinakekela kanjani?

Ukuzinakekela kubaluleke kakhulu uma uphila nomdlavuza. Nazi ezinye izinto ezingakusiza njengoba ubhekene nalesi sifo:

• Hlakulela imikhuba emihle yokudla nokuzivocavoca.Buza isazi sokudla okunempilo noma udokotela mayelana nokudla okunempilo okukufanele. Ukuzivocavoca ngangokunokwenzeka nakho kuhle kakhulu emzimbeni.
• Ukukhathala kuyisibonakaliso esivamile salesi sifo, futhi kungaba nemiphumela emibi yokwelashwa. Ngakho-ke lalela umzimba wakho. Uma uzizwa ukhathele, phumula hhayi kuphela uma ukwazi, kodwa futhi nalapho udinga.
• Kungase kudingeke uphile nalo mdlavuza isikhathi eside . Lezo yizindaba ezinhle ngempela. Kodwa-ke, ukuphila nesifo esingamahlalakhona kungaba yinselele engqondweni. Ngakho-ke, ukukhuluma nodokotela wezokwelapha noma ukujoyina iqembu lokusekela abantu abanalesi simo kungaba usizo kakhulu empilweni yakho yengqondo. Kuyimandla amakhulu futhi ukwazi ukuthi awuwedwa.

Kufanele ngimbone nini udokotela wami?

Ngemva kokuxilongwa ukuthi une-follicular lymphoma, udokotela wakho uzohlela ama-aphoyintimenti okulandelela ukuze aqaphe isimo sakho kanye nokwelashwa kwakho. Qiniseka ukuthi uyawagcina la ma-aphoyintimenti.

Kodwa-ke, uma ubona noma yiziphi izinguquko emzimbeni wakho noma izimpawu ezintsha (izimpawu ze-follicular lymphoma), bona udokotela wakho ngokushesha okukhulu bese umtshela ngakho. Uma kutholakala kusenesikhathi, kuba lula kakhulu ukukwelapha.

Umyalezo Wokugcina Wokuya Nasekhaya

Igama elithi umdlavuza liyasesabisa, akunjalo? Ngisho noma umdlavuza ukhula kancane njenge-Follicular Lymphoma, akulula. Ungase ungabi nazimpawu iminyaka eminingi. Kodwa uma izimpawu sezivele, kungase kudingeke udlule emjikelezweni wokwelashwa, ukuphulukiswa, ukuphinda ubuye, kanye nokwelashwa futhi. Ungase uzibuze nokuthi, 'Ngizokuqeda nini lokhu?'

Kodwa into ebaluleke kakhulu ukungalilahli ithemba. Abacwaningi bahlala bezama ukuthola izindlela ezintsha zokwelapha lesi sifo ukuze sibe yisifo esingelapheki.

Uma une-Follicular Lymphoma, khuluma nodokotela wakho futhi ucacise ngezinketho zakho zokwelapha. Ungesabi ukubuza imibuzo. Ngolwazi olufanele kanye nokusekelwa, uzokwazi ukubhekana nale nselele!

I- Follicular Lymphoma, i-Lymphoma, umdlavuza, ama-Lymph Node, izimpawu, ukwelashwa, i-B-Cell Lymphoma