Ingabe ngezinye izikhathi uzizwa ukhathele kakhulu? Ngesikhathi esifanayo, uke wabhekana nezimpawu ezingajwayelekile njengobuhlungu bamalunga, iminwe evuvukele, futhi ngezinye izikhathi iminwe yakho iphenduka ibe luhlaza okwesibhakabhaka uma ibhekene nomkhuhlane? Ingabe ukhathazwa nayizimpawu zalezi zifo ezibonakala ngesikhathi esisodwa? Khona-ke lesi kungaba yisimo esingavamile esibizwa ngokuthi i-Mixed Connective Tissue Disease, noma i-MCTD njengoba sikubiza ngamafuphi. Ungakhathazeki, ake sixoxe ngalokhu kalula.
Iyini ngempela i-MCTD?
Kalula nje, i-MCTD iyisifo sokuzivikela komzimba. Cabanga ngale ndlela: uhlelo lokuzivikela lomzimba wethu, uhlelo lokuzivikela, lukhona ukuze lusivikele emagciwaneni abangela izifo. Kodwa kulolu hlobo lwesifo, uhlelo lwethu lokuzivikela lucabanga ngephutha ukuthi izicubu zethu ezinempilo ziyizitha bese luqala ukuzihlasela.
Ukuhluka kwe-MCTD ukuthi akusona isifo esisodwa, kodwa kuyinhlanganisela yezimpawu zezinye izifo ezintathu ezinkulu zezicubu ezixhumeneyo. Yingakho ibizwa ngokuthi "Mixed". Ibizwa nangokuthi "overlap syndrome". Lezi zifo ezintathu yilezi:
- I-systemic lupus erythematosus (SLE): Ngokuvamile lokhu sikubiza ngokuthi 'i-lupus'.
- I-Scleroderma: Lokhu kubangela ukuthi isikhumba siqine futhi siqine.
- I-Polymyositis: Lokhu kubangela ubuthakathaka bemisipha nokuvuvukala.
Abanye abantu bangase babonise nezimpawu zezimo ezifana ne-dermatomyositis, i-rheumatoid arthritis, noma i-Sjögren's syndrome ngaphezu kwalezi zimpawu.
Ziyini izimpawu ze-MCTD?
Ngokuvamile, lezi zimpawu azibonakali zonke ngesikhathi esisodwa. Zivela ngokulandelana ngokuhamba kwesikhathi. Ngakho-ke, kungaba nzima ukuxilonga i-MCTD ekuqaleni.
| Isibonakaliso | Incazelo elula |
|---|---|
| Ukuzizwa ukhathele futhi ungenampilo | Ukuzizwa ukhathele kakhulu ngaphandle kwesizathu njalo. Ukuzizwa sengathi umzimba wakho awunampilo. |
| Ukushisa komzimba (umkhuhlane) | Akuyona imfiva ephezulu, kodwa ukushisa okuncane komzimba okuqhubekayo. |
| Ubuhlungu bemisipha namalunga | Ubuhlungu bemisipha nobuthakathaka, kanye nokuvuvukala, amalunga aqinile anobuhlungu. |
| Isenzakalo sikaRaynaud | Lesi yisibonakaliso esivamile kubantu abaningi. Uma bebhekene nomkhuhlane noma becindezelekile, ukugeleza kwegazi ezandleni, ezinyaweni, ekhaleni, nasemadlebeni kuyancipha, okubangela ukuba kuphenduke kube luhlaza okwesibhakabhaka ngokuzumayo. Bese kuba bomvu futhi bese kubuyela esimweni esijwayelekile. Ungase uzizwe ungenamizwa noma ubuhlungu phakathi nalesi sikhathi. |
| Ukuvuvukala kweminwe | Iminwe izizwa ivuvukele futhi inamaxolo. Ngezinye izikhathi lokhu kuyaphela ngemva kwezinsuku ezimbalwa, kodwa ngokuhamba kwesikhathi, abanye abantu bangase babe nokuqina kwesikhumba okwenza kube nzima ukugoba iminwe yabo (i-sclerodactyly). |
| Amabala esikhumba | Amabala noma izilonda ezibomvu noma ezibomvu ngokunsundu emaqakaleni. |
I-MCTD izizwa kanjani uma ivutha?
Abantu abanalesi sifo ngezinye izikhathi bangaba nezimpawu ezinzima kakhulu . Lokhu sikubiza ngokuthi 'ukuqhuma'. Phakathi nalesi sikhathi, ubuhlungu bamalunga kanye nobuhlungu bemisipha kungaba yinto engabekezeleleki. Njengomuntu one-'Rheumatoid arthritis', amalunga angavuvukala, aqine, futhi abe buhlungu. 'Isenzakalo sikaRaynaud' singavela kaningi futhi sibe sibi kakhulu.
Yini ebangela i-MCTD?
Imbangela eqondile yalesi sifo ayikatholakali. Akusona isifo esizuzwe njengefa ngokuqondile. Kodwa-ke, ucwaningo luthole ukuthi uma othile emndenini enezifo zezicubu ezixhumeneyo, abanye basengozini ethile yokuzithola. Ngaphezu kwalokho, kusolwa ukuthi amanye amagciwane, ukuchayeka kumakhemikhali anjenge-'polyvinyl chloride' kanye ne-'silica' nakho kungabangela lokhu.
Ubani osengozini enkulu yokuthola lesi sifo?
I-MCTD ivame kakhulu kwabesifazane abaneminyaka ephakathi kuka-20-40.Phakathi. Kodwa lokho akusho ukuthi amadoda noma abantu beminyaka ehlukile abakwazi ukuyithola. Noma ubani, kunoma yimuphi ubudala, angayithola le sifo.
Yiziphi izinkinga ezingaba khona ze-MCTD?
I-MCTD yisifo esingabangela izinkinga ezinkulu ngezinye izikhathi, ngakho-ke kubaluleke kakhulu ukugcina lesi sifo silawulwa.
Khumbula, akuwona wonke umuntu ozoba nazo zonke lezi zinkinga. Eziningi zalezi zingavinjelwa ngokwelashwa okufanele.
Nazi ezinye zezinkinga eziyinhloko:
- Umfutho wegazi ophezulu wamaphaphu: Lesi yisona sizathu esiyinhloko sokufa phakathi kweziguli ze-MCTD. Kwenzeka lapho ingcindezi emithanjeni yegazi ethwala igazi emaphashini ikhuphuka.
- Isifo samaphaphu angaphakathi: Ukuvuvukala kanye nezibazi zezicubu zamaphaphu.
- Isifo senhliziyo
- Ukulimala kwezinso
- Umonakalo womgudu wokugaya ukudla
- I-anemia
- Ukufa kwezicubu (i-necrosis)
- Ukulahlekelwa ukuzwa
Udokotela uyixilonga kanjani i-MCTD?
Njengoba sishilo ngaphambili, izimpawu zalesi sifo kungaba nzima ukuzibona ngoba zivela kancane kancane ngokuhamba kwesikhathi. Kungathatha iminyaka ukuthola ukuthi ngabe yi-MCTD. Uma unalezi zimpawu, cishe uzothunyelwa kudokotela ochwepheshe bezifo zamalunga kanye nezifo ezihlasela amasosha omzimba, obizwa ngokuthi i-rheumatologist .
Udokotela ufuna izinto ezine eziyinhloko okufanele azisole nge-MCTD:
1. Amazinga aphezulu ama-antibody e-anti-U1-RNP egazini: Lesi isivivinyo esiyinhloko sokuxilonga i-MCTD.
2. Ukungabi nezinkinga ezinkulu zezinso noma zesimiso sezinzwa esiyinhloko: Lezi zinkinga ngokuvamile zingaba zimbi kakhulu kubantu abane-lupus (SLE).
3. Ukuba khona kwesifo samathambo esibi kanye nomfutho wegazi ophezulu wamaphaphu: Lokhu akuvamile ukubonwa kodwa ku-lupus noma ku-scleroderma.
4. Isenzakalo sikaRaynaud kanye nokuvuvukala kweminwe: Lezi zimpawu zenzeka ku-25% kuphela weziguli ezine-lupus.
Yiziphi izindlela zokwelapha i-MCTD?
Akukho ukwelashwa kwe-MCTD okwamanje. Kodwa kunezindlela eziningi zokwelapha ezisebenzayo ezingakusiza ukulawula izimpawu zakho, ukuvimbela izinkinga, nokuphila impilo evamile. Ukwelashwa kuncike ezintweni ezifana nobukhulu bezimpawu zakho nokuthi yiziphi izitho zomzimba ezithintekile.
| Uhlobo lwesidakamizwa | Inhloso yokusebenzisa |
|---|---|
| Ama-Corticosteroids | Isibonelo: I-Prednisone. Yehlisa ukuvuvukala emzimbeni futhi icindezele umsebenzi wesimiso sokuzivikela komzimba. |
| Imithi yokulwa nomalaleveva | Isibonelo, i-Hydroxychloroquine. Vimbela ukuqubuka kwesikhumba futhi ulawule izimpawu ezincane. |
| Izithiyo zesiteshi se-calcium | Lawula ukwenzeka kukaRaynaud. Lokhu kuphumuza imisipha ezindongeni zemithambo yegazi. |
| Amanye ama-immunosuppressants | Uma kuthinteka izitho ezibalulekile (njengamaphaphu, inhliziyo), lawula isimiso somzimba sokuzivikela ngokuqinile. |
| Imithi yokulwa nomfutho wegazi ophakeme | Lawula umfutho wegazi ophezulu emaphashini. |
Yiziphi izinto ongazenza ukuze uzinakekele?
Ngaphezu kokuthatha imithi, ukwenza izinguquko ezincane endleleni yakho yokuphila kungasiza kakhulu ekulawuleni lezi zimpawu.
- Ukusetshenziswa kwemithi yobuhlungu: Ukuze uthole ubuhlungu obuncane kanye nokuvuvukala, ungathatha imithi engeyona eye-steroidal anti-inflammatory (NSAIDs) njenge-Ibuprofen, ngemuva kokubonisana nodokotela wakho .
- Ukuzivikela emakhazeni: Lokhu kubalulekile ukuvimbela ukugula kukaRaynaud. Gqoka amagilavu nezindlebe uma uphuma uma kubanda. Nciphisa ukuthintana namanzi abandayo kanye nokugcina efrijini ngokweqile.
- Ukugwema ukubhema:Ukubhema kunciphisa imithambo yegazi. Lokhu kungenza isimo sikaRaynaud sibe sibi kakhulu. Ngakho-ke uma ubhema, kubaluleke kakhulu ukuyeka.
- Nciphisa ukucindezeleka: Ukucindezeleka nakho kungabangela lesi simo sikaRaynaud. Ngakho zama ukuzola ingqondo yakho ngezinto ezifana nokuzivocavoca ukuphefumula nokuzindla. Funa usizo kumeluleki wezempilo yengqondo uma kudingeka.
Kunini lapho udinga ukubonana nodokotela?
Uma unezinye zezimpawu esixoxe ngazo ekuqaleni, ikakhulukazi uma ziphazamisa imisebenzi yakho yansuku zonke, kuwumqondo omuhle ukubona udokotela. Uma unezinhlungu ezintsha zemisipha noma amalunga, ukuvuvukala eminweni yakho, noma izimpawu zesifo sikaRaynaud, kungcono ukubona udokotela ukuze ahlolwe.
Eminye imibuzo ongayibuza udokotela:
* Iyini imbangela yezimpawu zami?
* Ingabe nginesifo esingaphezu kwesisodwa sezicubu ezixhumeneyo?
* Yiziphi izivivinyo okudingeka ngizenze?
* Yiziphi izindlela zokwelapha lesi simo?
* Yini engingayenza ukuze ngivimbele ukuqubuka kwesikhumba?
Ukuphila nalesi sifo kungaba yinselele ngezinye izikhathi. Kodwa ngokwelashwa okufanele nendlela yokuphila, ungaphila kahle. Hlala uxhumana nodokotela wakho futhi ukhulume ngokukhululekile ngezinto ezikukhathazayo.
Umlayezo Wokuya Nawe Ekhaya
- I-MCTD yisifo esiyinkimbinkimbi nesingavamile esibangela izimpawu zezifo eziningana ukuthi zihlangane.
- Ngenxa yokuthi izimpawu zivela ngokulandelana, kungathatha isikhathi ukuhlonza lesi sifo ngokunembile.
- Nakuba lesi sifo singelapheki ngokuphelele, kungenzeka ukulawula izimpawu, ukuvimbela izinkinga, nokuphila impilo evamile.
- Ukuzivikela emakhazeni, ukugwema ukubhema, nokulawula ukucindezeleka kusiza kakhulu ekunciphiseni izimpawu.
- Khuluma nodokotela wakho njalo ngesimo sakho bese uqhubeka nokuhlolwa okufanele kanye nokwelashwa. Awuwedwa!
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