Ingabe nawe unalezi zimpawu? Mhlawumbe lokhu kuyi-Pellagra!

Ingabe ngezinye izikhathi uzizwa sengathi awunawo amandla, ingabe uhlala unezinkinga zesisu, ngezinye izikhathi unesifo sohudo? Akukhona lokho kuphela, kodwa futhi unezinkinga zesikhumba, izimpawu ezingajwayelekile, njll.? Lezi zingaba izimpawu zezifo ezahlukene. Kodwa-ke, namuhla sizokhuluma ngesimo esihlukile kancane esivame ukuhlangana. Leso yisifo esibizwa ngokuthi i-pellagra .

Iyini i-Pellagra?

Kalula nje, i-Pellagra yisifo esibangelwa ukuntuleka kwevithamini ebizwa ngokuthi i-niacin , eyaziwa nangokuthi i-vitamin B3 . Lokhu futhi uhlobo lokungondleki kahle. Ngokukhethekile, kuwukuntuleka kwezakhamzimba ezincane. I-Niacin ibalulekile ekusebenzeni kwamaseli emzimbeni wethu. Ngakho-ke uma iphansi, imiphumela yayo ibonakala njengezimpawu kuwo wonke umzimba wethu, ikakhulukazi ezindaweni ezifana nesikhumba, umlomo, amathumbu, kanye nobuchopho. Uma ingelashwa kahle, i-Pellagra ingabangela umonakalo ohlala njalo ohlelweni lwezinzwa futhi ngezinye izikhathi ngisho nokufa. Manje ungase uzibuze ukuthi wonke umuntu uyakuthola lokhu. Esikhathini esiningi, umuntu odla ukudla okunempilo uthola inani elidingekayo le-niacin. Kodwa-ke, i-pellagra eyinhloko - ebangelwa ukuntuleka kwe-niacin ekudleni - iseyinkinga enkulu ezindaweni ezimpofu, ezingenakho ukudla. Kodwa-ke, emazweni athuthukile, njengeSri Lanka, ukuntuleka kwe-niacin kuvame ukuba yingxenye yezinye izimbangela. Okusho ukuthi, ezinye izimo zesifo noma izinto ezivimbela imizimba yethu ekumunceni noma ekusebenziseni i-niacin kahle.

Iyini iNiacin? Kungani siyidinga?

Imizimba yethu isebenzisa i-niacin ukuguqula amakhalori ekudleni esikudlayo kube amandla. Cabanga ngokudla esikudlayo njengophethiloli onika amandla imoto yethu. Ukuze lowo phethiloli usebenze, udinga ukuhluzwa kahle. Yilokho okwenziwa yi-niacin. I-niacin esiyithola ekudleni esikudlayo imuncwa ezicutshini zomzimba wethu ngamathumbu ethu amancane. Lapho, iba yi-coenzyme ebizwa ngokuthi i-Nicotinamide Adenine Dinucleotide (NAD) . Le NAD isiza ama-enzyme angaphezu kuka-400 ekusebenzeni komzimba wethu. Kalula nje, le NAD iyinto eyinhloko esiza amangqamuzana omzimba wethu ukuthi enze amandla (abizwa nangokuthi i-Adenosine Triphosphate (ATP) ). Ngaphezu kwalokho, i-NAD inegalelo emisebenzini eminingi ebalulekile, njengokulungiswa kwe-DNA nokuxhumana phakathi kwamaseli.

Ukuntuleka kwe-niacin kuthinta kanjani umzimba wami?

Ngenxa yokuthi i-NAD iyisici esibalulekile ekunikezeni amandla kumaseli, uma isiphelile, iqala ngokuthinta izinhlelo ezidinga amandla amaningi noma ezihlukana ngokushesha. Lokho kusho isikhumba sakho, ulwelwesi lomgudu wakho wokugaya ukudla (kusukela emlonyeni wakho kuya emathunjini akho), kanye nobuchopho bakho. Odokotela babiza izimpawu eziyinhloko ze-pellagra ngokuthi "ama-D angu-3":Uhudo, i-dermatitis, kanye ne-dementia. Abanye baze bangeze u-"D" wesine: ukufa . Uma kungelashwa iminyaka eminingi, kungaholela ekufeni.

1. Uhudo (i-mucositis yesisu)

Uhudo lwenzeka lapho ulwelwesi lwamathumbu akho (i-mucosa) lungavuseleli kahle. Cabanga ngakho njengokugqoka okuyisivikelo ngaphakathi kwamathumbu akho. Uma sekuphelile, amathumbu akho awakwazi ukugaya kahle ukudla noma ukuzivikela ekuthelelekeni noma ekulimaleni. Lokhu kungaholela ekuvuvukeni okuqhubekayo kusuka emlonyeni wakho kuya emathunjini akho. Lokhu kungabangela izimpawu ezifana nobuhlungu besisu, ukungagayi kahle ukudla, izilonda emlonyeni, kanye nolimi olubomvu noluvuvukele .

2. I-Dermatitis (Ukuzwela kwesikhumba)

I-Pellagra uhlobo oluthile lwesifo sesikhumba oluthinta isikhumba, ikakhulukazi ubuso, intamo, izingalo, imilenze, izintende zezandla, kanye nezinyawo, ezivezwa elangeni . Lapho amangqamuzana elahlekelwa amandla awo, amangqamuzana esikhumba azwela kakhulu ekukhanyeni kwelanga. Ekuqaleni, isikhumba siba bomvu futhi sibonakale sengathi sishiswe yilanga. Kamuva, izindawo ziba zimbi, zibe nama-scaly, futhi ngezinye izikhathi zingase zivele ama-plaque amnyama (anombala omningi) . Esinye sezimpawu zalesi sifo ibhande elimnyama elizungeze intamo. Libizwa ngokuthi "i-Casal's collar." Lokhu kuqanjwe ngodokotela uDon Gaspar Casal, owaqala ukuhlonza lesi sifo phakathi kwabalimi baseSpain ngo-1735.

3. I-Dementia (Ukulimala kobuchopho kanye nemizwa)

I-Pellagra yisifo esithinta wonke umzimba. Ngenxa yokuthi wonke amaseli emzimbeni alahlekelwa amandla awadingayo ukuze enze umsebenzi wawo, ekugcineni athinta ubuchopho kanye nesistimu yezinzwa. Izimpawu zokuqala zingase zingacaci kahle. Ungase uzizwe ukhathele, ungenandaba, futhi ube nobunzima bokugxilisa ingqondo . Noma ungase ube nezimpawu ezifana nokukhathazeka nokucindezeleka . Ngokuhamba kwesikhathi, lezi zimpawu zingaqhubekela ekudidekeni nasekukhohliseni . Ezimweni ezimbi kakhulu, kungenzeka ukuthi kube nokuwohloka komqondo okungapheli, kanye nezinkinga zezinzwa ezifana nobunzima bokulinganisela nokuhamba, ukudikiza kwemisipha, kanye nokuthuthumela .

Iphi iPellagra evame ukubonwa?

Ngokomlando, i-pellagra itholakale kubantu abampofu emhlabeni wonke, emazweni afana neYurophu, i-Afrika, i-Asia, kanye neNingizimu Melika. Ivame ukubonakala kubantu abadla ukudla okulinganiselwe kakhulu. Ikakhulukazi kulabo ababenamaprotheni aphansi futhi ababedla ukudla okusekelwe kummbila. Lokhu kungenxa yokuthi i-niacin idinga amaprotheni nama-amino acid ukuze amuncwe kahle ngumzimba. Nakuba ummbila uqukethe i-niacin, usesimweni "esiboshiwe" imizimba yethu engenakukwazi ukumunca kalula.

EMelika Ephakathi naseNingizimu, ngokwesikoUma kwenziwa ama-tortilla ngommbila , ummbila ucwiliswa emanzini kalamula ubusuku bonke. Le nqubo ikhipha i-niacin emmbileni futhi iwenze ukwazi ukuwumunca kalula. Yingakho i-pellagra ingavamile kakhulu kulezo zindawo.

Kulezi zinsuku, i-Pellagra ayivamile emazweni aseNtshonalanga athuthukile njengeMelika. Lokhu kungenxa yokuqinisa isinkwa nelayisi nge-niacin. Kodwa-ke, i-Pellagra eyinhloko isabonakala ezindaweni ezingakathuthuki zomhlaba, ikakhulukazi phakathi kwabantu bezizwe abadla ummbila njengokudla kwabo okuyisisekelo. Lesi simo sisakhona eNdiya, eShayina, nakwezinye izingxenye ze-Afrika. Nakuba i-Pellagra eyinhloko ingavamile emazweni afana neSri Lanka, kufanele sikhathazeke nge-Pellagra ebangelwa yizimbangela zesibili .

Ziyini izimpawu ze-Pellagra?

Nazi ezinye zezimpawu ezivamile ze-pellagra:

• Uhudo oluqhubekayo , ngezinye izikhathi oluhambisana negazi.
• Ubuhlungu besisu kanye nokungagayeki kahle kokudla .
• Ukulahlekelwa yisifiso sokudla , isicanucanu , nokuhlanza .
• Ukuqubuka kwesikhumba okunokulunywa noma ubuhlungu esikhumbeni .
• Izilonda zomlomo kanye nolimi olubomvu noluvuvukele.
• Ukukhathala okukhulu, ubuthakathaka, kanye nokudinwa.
• Ukushintshashintsha kwemizwa, ukucindezeleka.
• Izimpawu zesimiso sezinzwa - isibonelo, ukuthuthumela kanye nokungazweli ezithweni.
• Ukusangana kanye nokuwohloka komqondo.

Yiziphi izimbangela ze-Pellagra?

Imbangela eyinhloko ukudla okungenayo i-niacin eningi. Sithola i-vitamin B3 (niacin) ekudleni okuhlukahlukene. Kodwa-ke, abantu abanokukhetha ukudla okulinganiselwe bangase babe nezakhamzimba ezintulayo. I-Pellagra ingavela futhi ngenxa yezimbangela zesibili . Okungukuthi, ezinye izimo zempilo ezivimbela umzimba wakho ekumunceni noma ekusebenziseni i-niacin ngendlela efanele. Ezinye izibonelo yilezi:

• Izifo zesisu ezibangela ukungamuncwa kahle kokudla - isibonelo , Isifo Samathumbu Esivuvukalayo (IBD) nomaI-cirrhosis yesibindi.
• Ukuphazamiseka kokusebenzisa utshwala: Ukuphuza utshwala ngokweqile kungalimaza izitho zomzimba ezifana nesibindi futhi kunciphise ikhono lomzimba lokumunca izakhamzimba ezifana ne-niacin. Lokhu kungaholela ekungondleki kahle.
• Ukuhlinzwa kwesisu: Ngemva kokuhlinzwa okuthile kokukhuluphala, i-mucosa yamathumbu ingonakala, okuholela ekusweleni okuhlukahlukene kwezakhamzimba ezincane, okuhlanganisa ne-niacin.
• I-anemia yokuntuleka kwensimbi: Umzimba udinga nensimbi ukuze uguqule futhi usebenzise i-niacin.
• Isifo sikaHartnup: Lesi yisifo esibangelwa izakhi zofuzo. Sivimbela umzimba ekumunceni ama-amino acid. Lawa ma-amino acid abalulekile ekwenzeni amavithamini.
• I-Carcinoid syndrome: Kulokhu, ukukhiqizwa kwe-niacin ngamaseli omdlavuza kuyancishiswa.
• Imithi ethile: Eminye imithi, ikakhulukazi imithi yokunciphisa izinhlungu kanye nemithi yokwelapha ngamakhemikhali, ingaphazamisa ukusebenza kwe-niacin.
• Ukutheleleka nge-HIV: Ukutheleleka nge-HIV kubangela ukwehla kwamazinga e-niacin emzimbeni.

I-Pellagra itholakala kanjani?

Uma ubona udokotela, uzokuhlola futhi akubuze ngezimpawu zakho, umlando wakho wezokwelapha, kanye nokudla kwakho. Uma kusolwa ukuthi i-pellagra, ukuhlolwa komchamo kungenziwa ukuqinisekisa ukuxilongwa. Amazinga amakhemikhali athile emchameni wakho angakutshela ukuthi une-niacin eyanele yini emzimbeni wakho. Udokotela wakho angakunikeza nezithasiselo ze-niacin ukuze abone ukuthi ziyasiza yini. Leyo enye indlela yokuthola lesi sifo.

Yiziphi izindlela zokwelapha i-Pellagra?

I-Pellagra ibangelwa ukuntuleka kwe-niacin, noma i-vitamin B3. Ngakho-ke, ukwelashwa okungcono kakhulu kwayo ukugcwalisa umzimba ngesakhamzimba esingekho. Lokho kusho ukunikeza izithasiselo ze-niacin. Abantu abaningi baqala ukululama ngokushesha uma sebeqala ukuzithatha. Kodwa-ke, kungadingeka ukwelashwa okwengeziwe ezintweni ezifana nezilonda zesikhumba kanye nezilonda zomlomo.

Into ebaluleke kakhulu ukuthi uma une-pellagra ngenxa yesizathu sesibili, okungukuthi, esinye isifo, khona-ke udinga ukwelapha kahle leso sifo esiyisisekelo.

Ingabe ikhona imiphumela emibi ekwelashweni?

Uma uthatha umuthi njengoba uyalelwe udokotela wakho, izithasiselo ze-niacin ngokuvamile azibangeli imiphumela emibi emikhulu. Kodwa-ke, uma uphuza ngokweqile, kungase kube nemiphumela emibi ethile. Kodwa-ke, umuntu onokuntuleka emzimbeni wakhe ngeke asebenzise ngokweqile kalula. Uma lokho kwenzeka, izinto ezilandelayo zingenzeka:

• Ukuhlanzeka kwesikhumba.
• Ukuluma kanye nokuqubuka kwesikhumba.
• Ukuqunjelwa kanye nokungagayeki kahle kokudla.
• Ikhanda elibuhlungu kanye nesiyezi.

Indlela yokuvimbela i-Pellagra?

Ukudla ukudla okulinganiselayo kuyindlela elula yokuhlala unondlekile. Uma ukukhetha kokudla kulinganiselwe, ukudla okuqinisiwe kanye nezithako zokudla kungasiza. Cishe ama-milligram angu-15 e-niacin ngosuku anele umuntu omdala onempilo. Leli nani livame ukutholakala esithasiselweni sevithamini B-complex. Okunye kokudla okucebile kakhulu nge-niacin kufaka phakathi:

• Isibindi senyama yenkomo
• I-Beetroot (Ama-Beet)
• Imvubelo yobhiya
• Isinkwa esicebile kanye nokolweni
• Izinhlanzi ezinamafutha, njenge-salmon ne-tuna
• Amantongomane
• Izambane
• Izinkukhu
• Ilayisi
• Imbewu yelanga
• Isosi ye-spaghetti

Uma unesifo esingamahlalakhona esikwenza ube namathuba amaningi okuthola i-pellagra, khuluma nodokotela wakho ngezindlela zokuyivimbela isikhathi eside. Lokhu kungafaka phakathi ukwenza izinguquko ekudleni kwakho, izithasiselo zokudla, noma imithi oyiphuzayo.

Kuthatha isikhathi esingakanani ukululama ePellagra?

Uma uqala ukuthatha izithasiselo ze-niacin, abantu abaningi baqala ukuzizwa bengcono ezinsukwini ezimbalwa. Izimpawu zokugaya ukudla (njengohudo) zivame ukuthuthuka kuqala , ngokuvamile phakathi nesonto lokuqala. Izilonda zesikhumba nomlomo zingathatha amasonto amabili ukuphola. Amanye amacala abucayi angathatha isikhathi eside. Ukulimala okukhulu kwemizwa kanye nokuwohloka komqondo kungase kungapheli. Ukuze kuvinjelwe i-pellagra eyinhloko eyengeziwe, odokotela batusa ukugcina ukudla okulinganiselayo. Ukuntuleka kwe-niacin kuvame ukuhambisana nokunye ukuntuleka kwezakhamzimba ezincane. Konke lokhu kungalungiswa ngokudla okuhle. Ukwelapha i-pellagra yesibili kungaba nzima kakhulu. Ngenkathi izithasiselo zingasiza, uma umzimba ungakwazi ukugaya i-niacin kahle, lolo sizo lungase lunganele. Ezimweni ezinjalo, ukululama kuncike ekuboneni nasekuphatheni isimo esiyisisekelo esibangele i-pellagra. Lokhu kungaba inqubo ende, kuye ngesifo.

Okokugcina, izinto okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

Nakuba i-pellagra eyinhloko isusiwe kakhulu emazweni athuthukile, isakhona phakathi kwabantu abampofu abanokudla okulinganiselwe. Emazweni afana nelethu, ukuntuleka kwe-niacin yesibili kusalokhu kuyingozi ngenxa yokusebenzisa utshwala kanye nezimo ezithile zezokwelapha (ikakhulukazi lezo eziphazamisa ukumuncwa kwezakhamzimba).

Into ebaluleke kakhulu ukukhumbula ukuthi nakuba ukudla okunomsoco kuqala ngokudla, kuphelela ngaphakathi emzimbeni.Izinto eziningi emzimbeni wakho kudingeka zisebenze kahle. Uma unezimpawu ezibonisa ukuthi kukhona okungahambi kahle, ikakhulukazi uma unezinkinga ohlelweni lwakho lokugaya ukudla, qiniseka ukuthi ufuna iseluleko sezokwelapha. Ngisho nokuntuleka kwamavithamini amancane kungaba nomthelela omkhulu empilweni yakho. Ngakho-ke, yidla ukudla okulinganiselayo, uphile impilo enempilo, futhi ubone udokotela ngokushesha okukhulu uma unezinkinga.

I-Pellagra, i-niacin, i-vitamin B3, ukuntuleka kokudla okunempilo, izifo zesikhumba, isifo sohudo, i-dementia