Ingabe lokhu kuyingozi nasezinso zakho? (I-Renal Papillary Necrosis) Ake sifunde ngakho!

Uyazi ukuthi izinso ezimbili ezincane emzimbeni wethu zisebenza kangakanani? Eqinisweni, izinso ziyizitho eziyinhloko ezihlunga ukungcola futhi zihlanze igazi emzimbeni wethu. Kodwa-ke, ngezinye izikhathi lezi zinso zingaba nezifo esingazilindele. Namuhla sizokhuluma ngesimo esibucayi kancane, kodwa uma usazi, singakusiza ukuthi usilawule futhi usivimbele.

Zisebenza kanjani izinso? Kuyini i-Renal Papillary Necrosis?

Kalula nje, izinso zethu zifana nezihlungi ezimbili ezinkulu emzimbeni wethu. Umsebenzi wazo oyinhloko ukuhlunga imfucuza engafuneki egazini bese uyikhipha njengomchamo. Ukuze wenze lokhu, igazi lingena ezinso futhi lidlule eziteshini eziningi ezincane. Le mfucuza iqoqwa engxenyeni engaphandle yezinso bese ifika phakathi kwezinso, okuyi -kidney medulla . Nazi izingxenye ezimise okwe-funnel. Iphuzu lale mfunnel, ebizwa ngokuthi i-renal papilla, liqoqa umchamo. Ukusuka lapho, umchamo udlula kuma-ureter uye kwesinye bese uphuma. Yileyo ndlela izinso zethu ezisebenza ngayo.

I-renal papillary necrosis esikhuluma ngayo manje ukufa kwamaseli nezicubu engxenyeni ephakathi yezinso (`Medulla`) kanye ne-renal papilla (`Renal Papilla`) engikushilo ekuqaleni. Cabanga nje, lapho lezo zindawo zingasebenzi kahle, umsebenzi owenziwa yizinso awusebenzi kahle, akunjalo? Ngenxa yalokhu, izinso ziba buthaka kancane kancane, futhi ekugcineni zingaholela ekuhlulekeni kwezinso .

Ubani osengozini enkulu yalesi simo?

Lesi simo (i-Renal Papillary Necrosis) sivame kakhulu kubantu abaneminyaka engaphezu kwengu-60. Odokotela baphinde baveze ukuthi abesifazane banamathuba amaningi okuba naso kunabesilisa.

Yiziphi izimbangela ze-Renal Papillary Necrosis?

Kunezimbangela eziningana eziyinhloko ezibangela ukuvela kwalesi sifo. Ake sibheke ukuthi ziyini.

• Isifo Sikashukela : Lesi yisona sizathu esibaluleke kakhulu nesivamile. Abantu abanesifo sikashukela esingalawulwa kahle basengozini enkulu yokulimala kwezinso. Amazinga aphezulu kashukela egazini isikhathi eside alimaza imithambo yegazi ethambile ezinso.
• Ukusebenzisa ngokweqile imithi yobuhlungu (ama-NSAID) : Uma usebenzisa imithi yobuhlungu njalo (imithi engeyona i-steroidal anti-inflammatory, noma ama-NSAID) njenge-aspirin, i-ibuprofen, noma i-naproxen isikhathi eside ngaphandle kokubonisana nodokotela, kufanele uqaphele kakhulu. Ukuthatha imithi eminingi kakhulu kungabangela ukuthi imithambo yegazi ezinso inciphe futhi yonakalise i-renal papillae.
• Isifo Se-Sickle Cell: Lesi yisifo esibangelwa ufuzo. Kulesi sifo, isimo samaseli abomvu egazi siyashintsha futhi angabhajwa emithanjeni yegazi. Lokhu kungaholela nasekuphazamisekeni kokunikezwa kwegazi ezinso (i-Renal Papillary Necrosis).

Ngaphezu kwalezi zimbangela eziyinhloko, ezinye izimo eziningana zingabangela ne-Renal Papillary Necrosis:

• Isifo Sesibindi Esingapheli
• I-Pyelonephritis, ukutheleleka kwamagciwane ezinso (okungalimaza i-renal papillae)
• Isifo Sofuba Sezinso, isifo esithinta izinso ngaphandle kwamaphaphu
• I-Renal Vein Thrombosis (ukuqhekeka kwegazi emthanjeni othwala igazi elisuka ezinso)
• Ukuvaleka komchamo (isibonelo, ngenxa yamatshe omchamo)
• I-Vasculitis, ukuvuvukala kwemithambo yegazi

Into ebalulekile ukuthi akuwona wonke umuntu onesinye noma ngaphezulu salezi zimbangela ozothola i-Renal Papillary Necrosis, kodwa ingozi iphakeme.

Ingabe lokhu kuthinta izinso zombili?

Yebo, kubikwa ukuthi kubantu abayisikhombisa kwabayishumi , lesi simo (i-Renal Papillary Necrosis) sithinta zombili izinso .

Ziyini izimpawu ze-(Renal Papillary Necrosis)?

Ezigabeni zokuqala zalesi sifo, kungase kungabi nazimpawu . Yingakho kunzima ukukubona nokukwelapha kusenesikhathi. Cabanga nje, awunazo izinkinga, kodwa izinso zakho zingase zonakale ngaphakathi. Kodwa-ke, kungenzeka futhi ukuthi lokhu kutholakale ngengozi lapho kuhlolwa esinye isifo.

Kodwa-ke, lapho isimo (i-Renal Papillary Necrosis) siba sibi kakhulu, izimpawu ezinjengalezi zingase zivele:

• Ukuchama okubuhlungu (i-Dysuria)
• Umkhuhlane kanye nokubanda (ikakhulukazi uma kuhambisana nokutheleleka)
• Igazi elisemchameni (`Hematuria`) - Inani legazi lingabonakala emehlweni (umchamo ungaba bomvu noma ube nsundu), noma ungaba mncane kangangokuthi ungabonakala kuphela ngaphansi kwe-microscope.
• Ukudinga njalo ukuchama ebusuku (`Nocturia`)
• Ukwanda okungavamile kwenani lamaseli amhlophe egazi emchameni (`Pyuria`) - lokhu kusho ukuthi umchamo ungase ubonakale njengobomvu, futhi umchamo ungase ubonakale unamafu.
• Ubuhlungu obukhulu kuzo zombili izinhlangothi zomhlane, phakathi kwezimbambo namathambo ezinqeni (lapho kukhona khona izinso). Lobuhlungu bungavela ngokuzumayo noma bukhule kancane kancane.
• Ukutheleleka njalo komgudu womchamo.

I-Renal Papillary Necrosis itholakala kanjani?

Odokotela bazokwenza izivivinyo eziningana ukuze baxilonge lesi simo (i-Renal Papillary Necrosis). Ngemva kokulalela izimpawu zakho kanye nomlando wezokwelapha, bangase ba-ode izivivinyo ezifana nalezi:

• I-Urography: Lokhu kuhilela ukuthatha i-X-ray, i-CT scan, noma i-MRI yezinso zakho. Ngaphambi kokuhlolwa, uzonikezwa idayi ekhethekile (idayi) ngomthambo. Lokhu kusiza ukubona ngokucacile izindawo zomonakalo ezinso kanye nezinguquko ku-papillae.
• I-Ureteroscopy : Lokhu kuhilela ukufaka ipayipi elincane neliguquguqukayo (elinekhamera ekugcineni) nge-urethra ukuze libheke ngqo ngaphakathi kwesinye, kuma-ureter, nasezinso. Lokhu kuvumela isimo sama-papillae ukuba sibonakale kahle.
• Ukuhlolwa Kwezinso : Kulolu vivinyo, kuthathwa ingxenye encane yezicubu ezinso kusetshenziswa inaliti ekhethekile bese kuhlolwa ngaphansi kwe-microscope. Lokhu kungasiza ekunqumeni ukuthi amaseli afile noma ukuthi izicubu zonakele.

Ukuhlolwa kwegazi nomchamo

Ngaphezu kwalokho, ukuhlolwa kwegazi nomchamo ukuhlola ukusebenza kwezinso nakho kubaluleke kakhulu:

• Ukuhlolwa kwe-urea nitrogen egazini (BUN) : Lokhu kulinganisa inani le-urea nitrogen egazini. Lokhu kuwumkhiqizo ongcolile. Leli zinga liyakhuphuka egazini uma izinso zingasebenzi kahle.
• Ukuhlolwa kwe-Creatinine : I-Creatinine ingenye imfucuza ekhiqizwa ngesikhathi sokusebenza kwemisipha okuvamile. Ngokuvamile ikhishwa yizinso. Uma izinga layo liphezulu egazini, kubonisa nokuthi izinso azisebenzi kahle.
• Izinga Lokuhlunga Le-Glomerular Elilinganiselwe (i-eGFR) : Lokhu kubalwa ngokubheka izici ezifana nezinga le-creatinine egazini lakho, ubudala, ubulili, kanye nosayizi womzimba. Inani le-eGFR likutshela ukuthi lingakanani igazi elihlungwa yizinso zakho ngomzuzu. Uma leli nani liphansi, kulapho izinso zakho zingasebenzi kahle khona.
• Ukuhlolwa komchamo : Lokhu kuhilela ukuthatha isampula yomchamo bese uwuhlola ngamehlo (umbala, ukucaca), nge-microscope (yamangqamuzana egazi, amaseli obovu, amabhaktheriya, udoti we-papillary), kanye nangamakhemikhali (yamaprotheni, ushukela). Ngezinye izikhathi, izingcezu ze-renal papillae nazo zingabonakala ngaphansi kwe-microscope.
• Isilinganiso seprotheyini yomchamo/i-creatinine : Lokhu kulinganisa ukuthi ingakanani iprotheyini emchameni. Izinso eziphilile zikhipha iprotheyini encane kakhulu. Amazinga aphezulu eprotheyini emchameni ayisibonakaliso sokulimala kwezinso.

Yiziphi izinkinga ezingaba khona ngenxa ye-(Renal Papillary Necrosis)?

Uma lesi simo (i-Renal Papillary Necrosis) singelashwa ngendlela efanele, lesi simo singaba sibi kakhulu futhi siholele ezinkingeni ezinkulu.

• Isifo Sezinso Esingapheli (CKD) : Ngenxa yokulimala okuqhubekayo kwezinso, ukusebenza kwazo kwehla kancane kancane, okuholela esifweni sezinso esingapheli.
• Ukwehluleka KwezinsoUma isimo siba sibi kakhulu, izinso zingase ziyeke ukusebenza ngokuphelele, okusho ukuthi zingase zihluleke ukusebenza kahle kwezinso.
• Ukuze usinde, ungadinga i-dialysis (ukuhlanza igazi lakho ngomshini) noma ukufakelwa izinso .
• Kutholakale nokuthi lesi simo sandisa ingozi yokuthola uhlobo lomdlavuza olubizwa ngokuthi umdlavuza we-transitional cell, oluvela ezinso noma e-ureter.
• Kukhona futhi ingozi yokutheleleka okukhulu (i-sepsis).

Iphathwa kanjani i-Renal Papillary Necrosis?

Akukho ukwelashwa okuqondile kwe-Renal Papillary Necrosis. Ukwelashwa okuyinhloko ukwelapha imbangela eyisisekelo yalesi simo . Isibonelo:

• Uma kungenxa yesifo sikashukela, kubalulekile ukulawula isifo sikashukela kahle.
• Uma kungenxa yokusebenzisa ama-NSAID, yeka ukuthatha leyo mithi.
• Uma kungenxa yokutheleleka, mnike ama-antibiotic.
• Uma kukhona ukuvaleka kwendlela yomchamo, kufanele kususwe.

Umgomo oyinhloko ukunciphisa umonakalo owengeziwe ezinso nokugcina ukusebenza kwezinso ngangokunokwenzeka.

Impumelelo yokwelashwa incike ebangeni lomonakalo wezinso kanye nembangela yalesi sifo. Kwezinye izimo ezinzima kakhulu, lesi sifo singaqhubeka siba sibi naphezu kokwelashwa. Kodwa-ke, ezimweni ezinganzima kangako, futhi uma imbangela yelashwa ngokushesha, ukusebenza kwezinso kungase kuzinze noma kuthuthuke kancane.

Ngingazivikela yini ku-Renal Papillary Necrosis?

Yebo, kunezinto esingazenza ukuze sizivikele kulesi simo, ngezinga elikhulu.

• Into ebaluleke kakhulu ukugcina impilo yakho iyonke . Ukudla ukudla okunempilo, ukuphuza amanzi anele, nokuzivocavoca njalo kubalulekile.
• Uma uthatha imithi yokubulala izinhlungu ethengiswa ngaphandle kwemithi kadokotela (ama-NSAID), sebenzisa kuphela njengoba kuyalelwe ephaketheni noma njengoba kuyalelwe udokotela. Ungawathathi kaningi noma isikhathi eside kunokudingekile. Ungawathathi njalo ngenxa yezinhlungu ezincane noma ngenxa yekhanda elibuhlungu.
• Uma unesifo sikashukela (i-Diabetes Mellitus), isifo se-sickle cell (i-Sickle Cell Disease), noma ezinye izifo ezingabangela isifo sezinso (i-Renal Papillary Necrosis), landela imiyalelo kadokotela wakho ngqo. Yiya emitholampilo ngesikhathi. Thatha imithi oyinikeziwe. Landela ukudla okufanele.
• Kubaluleke kakhulu ukuba nezivivinyo zelebhu ukuhlola ukusebenza kwezinso njalo njengoba kuqondiswe udokotela wakho, nokubona noma yiziphi izinguquko kusenesikhathi.

Lingakanani izinga lokululama komuntu onalesi sifo?

Ukubikezela kwakho kuncike embangela yesifo, izinga lomonakalo wezinso, impilo yakho iyonke, nokuthi uqala ngokushesha kangakanani ukwelashwa.

• Kubantu abanesifo sikashukela, imiphumela ingase ingabi mihle kangako , njengoba isifo sikashukela siyisifo sesikhathi eside futhi asilawulwa kahle ngaso sonke isikhathi. Uma unesifo sikashukela, ukusilawula kahle ngangokunokwenzeka kuzosiza kakhulu ekuvimbeleni ukulimala kwezinso.
• Ezimweni ezimbi kakhulu (i-Renal Papillary Necrosis), kungaholela ekuhlanjululweni kwegazi kanye nokufakelwa kwezinso . Uma kwenzeka ukutheleleka, kungaba yingozi empilweni. Kukhona ithuba lokufa ngenxa yokwehluleka kwezinso.
• Esifweni se-sickle cell, i-renal papillary necrosis ingenye yezinkinga eziningana ezingase zenzeke ezinso. Uma zonke lezi zinkinga zihlanganiswa, isikhathi sokuphila kwesiguli singancishiswa kakhulu.

Kufanele ngimbone nini udokotela?

Uma unesinye noma ngaphezulu salezi zimpawu, ungachithi isikhathi futhi nakanjani ubone udokotela :

• Uma unegazi emchameni wakho (umchamo uphenduka ube bomvu, upinki, noma ube nsundu).
• Uma unomkhuhlane noma ukubanda (ikakhulukazi uma unezinye izimpawu).
• Uma uzwa ubuhlungu noma ukushisa lapho uchama.
• Uma unezinhlungu ezintsha noma eziya ziba zimbi kakhulu ohlangothini ngalunye lomhlane wakho, endaweni ephakathi kwamathambo akho enqulwini kanye nezimbambo (indawo yezinso).
• Uma uthola izifo zomgudu womchamo njalo.
• Uma uzwa ukuncipha kokuchama noma ukuvuvukala emilenzeni nasemaqakaleni akho (lokhu kungaba izimpawu zokungasebenzi kahle kwezinso).

Khumbula, lezi zimpawu zingabangelwa nezinye izifo. Kodwa-ke, kubalulekile ukuhlolwa ngudokotela ukuze uthole imbangela eqondile.

Okokugcina, okufanele ukukhumbule (Umyalezo Wokuya Ekhaya)

Izinso zethu ziyisitho esibalulekile emzimbeni wethu, zenza umsebenzi othule futhi obalulekile. Zihlunga ukungcola futhi zigcine ibhalansi yamanzi nosawoti emzimbeni. Isifo sikashukela esingalawulwa, ukusetshenziswa ngokweqile kwemithi yobuhlungu (ama-NSAID), kanye nezinye izimo zezokwelapha ezahlukahlukene kungalimaza izinso, okuholela ezimweni ezimbi kakhulu njenge-Renal Papillary Necrosis.

Ingxenye embi kakhulu ngalesi sifo ukuthi ungase ungabi nazimpawu ezigabeni zokuqala. Ngakho-ke, uma unesifo sikashukela, usebenzisa njalo ama-NSAID, noma unezinye izici eziyingozi zesifo sezinso, khuluma nodokotela wakho ngezindlela zokuvikela izinso zakho. Ngokuhlola njalo nokulandela indlela yokuphila enempilo, ungagcina izinso zakho ziphilile. Ukuqwashisa kusenesikhathi kanye nesenzo kuhlale kuyinto engcono kakhulu ongayenza.

Izinso , i-renal papillary necrosis, isifo sezinso, isifo sikashukela, ama-NSAID, ukwehluleka kwezinso, umchamo