Ingabe ngezinye izikhathi uzizwa ukhathele ngendlela engajwayelekile futhi ukhathele ngaphandle kwesizathu? Ingabe ulahlekelwa yisifiso sokudla , wehlisa isisindo , noma unesizungu ? Kungenzeka ukuthi uke waphawula nokuthi isikhumba sakho, ikakhulukazi izindololwane namadolo akho, sesiphenduke saba nsundu kancane. Ungamane ungazinaki lezi zinto. Zingaba uphawu lokuthile okubalulekile okwenzekayo emzimbeni wakho. Namuhla sikhuluma ngesinye sezimo ezinjalo, i-Addison's Disease .
Kalula nje, siyini isifo sika-Addison?
Cabanga ngemizimba yethu njengenkampani enkulu. Le nkampani ineqembu " lezithunywa zamakhemikhali" ezishintshana imiyalezo ukuze kugcinwe imisebenzi ehlukahlukene isebenza kahle. Sibiza lawa ma-hormone ngokuthi.
Ngaphezu kwezinso zethu, njengezigqoko ezimbili ezincane, kunezindlala ezimbili ezincane. Lezi yizindlala ze-adrenal . Lezi zindlala zikhiqiza ama-hormone amabili abaluleke kakhulu abalulekile empilweni yethu. Yi -cortisol ne -aldosterone .
Isifo sika-Addison yisimo lapho izindlala ze-adrenal zonakala khona ngesizathu esithile futhi zingakwazi ukukhiqiza inani elidingekayo lala ma-hormone. Lesi yisimo esingavamile kakhulu. Kodwa kubaluleke kakhulu ukuqaphela lokhu.
Uyini umsebenzi wama-hormone amabili?
- I-Cortisol: Lokhu kufana "nomphathi wokucindezeleka" womzimba wethu. Le hormone ilungiselela umzimba ukubhekana nokugula, ingozi, kanye nokucindezeleka. Iphinde isize ekulawuleni umfutho wegazi, amazinga kashukela egazini, kanye nokusetshenziswa kwamaprotheni, ama-carbohydrate, namafutha.
- I-Aldosterone: Le hormone "ilawula usawoti namanzi" emzimbeni wethu. Isiza izinso zethu ukugcina amazinga kasawoti (i-sodium) kanye ne-potassium emzimbeni. Iphinde ilawule umfutho wegazi lethu.
Uma la ma-hormone ephansi, wonke umsebenzi womzimba uyaphazamiseka. Yilokho okwenzekayo kwisifo sika-Addison.
Ziyini izimpawu zesifo sika-Addison?
Izimpawu zesifo sika-Addison ziza kancane kancane. Ngakho-ke ngezinye izikhathi kungathatha isikhathi ukuqaphela ukuthi yisifo. Lezi zimpawu zifana nezezinye izifo ezivamile, ngakho-ke zingaqondwa kabi.
Bheka ithebula elingezansi ukuthola izici eziyinhloko ozozibona.
| Isibonakaliso | Incazelo |
|---|---|
| Ukukhathala okungapheli kanye nobuthakathaka bemisipha | Ukuzizwa ukhathele futhi ungenampilo usuku lonke, kungakhathaliseki ukuthi uthola ukuphumula okungakanani. |
| Ukunsundu/ukuba mnyama kwesikhumba (i-Hyperpigmentation) | Ubumnyama besikhumba ezindaweni ezifana nezindololwane, amadolo, amafinyila, izindebe, nezinsini. Ngisho nezibazi ezindala zingaba mnyama. |
| Ukulahlekelwa yisifiso sokudla kanye nokwehla kwesisindo | Ukulahlekelwa yisifiso sokudla kanye nokwehla kwesisindo okubangelwa yiso. |
| Umfutho wegazi ophansi (i-Hypotension) | Uma uzizwa unesizungu, ikakhulukazi uma usukuma uhleli, kungaba ngenxa yomfutho wegazi ophansi. Ungase ulahlekelwe ngisho nokuqwasha. |
| Ukufisa usawoti ngokweqile | Njengoba amazinga kasawoti emzimbeni ehla, kuba nesifiso esiqhubekayo sokudla ukudla okunosawoti nezinto ezifana nama-pickle. |
| Ezinye izici | Isicanucanu, ukuhlanza, ubuhlungu besisu, ukuqunjelwa, ushukela wegazi ophansi (i-hypoglycemia), ukungahlaliseki kwengqondo, kanye nokujikeleza kokuya esikhathini okungajwayelekile kwabesifazane. |
Yiziphi izimbangela zesifo sika-Addison?
Imbangela eyinhloko yesifo sika-Addison yisifo esibangelwa ukuzivikela komzimba.Kalula nje, lokhu kwenzeka lapho amasosha omzimba wethu eqala ukuhlasela futhi abhubhise izindlala zethu ze-adrenal. Lokhu kuyimbangela yama-70% eziguli ze-Addison.
Ngaphezu kwalokho, kungase kube nezinye izizathu.
- Ukutheleleka: Ukutheleleka kwesikhathi eside njengesifo sofuba kanye ne-HIV kungalimaza izindlala ze-adrenal.
- Umdlavuza: Amaseli omdlavuza akheke kwenye indawo asakazekela ezindlaleni ze-adrenal.
- Ukopha kwangaphakathi: Ukopha ngaphakathi kwezindlala ze-adrenal.
- Izimbangela zofuzo: Kukhona futhi ingozi yokuthola lesi sifo ngenxa yezimo ezithile zofuzo.
- Ukuhlinzwa: Uma uke wahlinzwa ukuze kususwe izindlala ze-adrenal.
Ukuthola kanjani lokhu, Dokotela?
Uma unezinye zalezi zimpawu, bona udokotela womndeni wakho ngokushesha okukhulu. Uzokuhlola futhi akuthumele kuchwepheshe uma kudingeka.
Ukuhlolwa kwegazi okuningana kusetshenziswa kakhulu ukuthola isifo.
1. Ukuhlolwa kwegazi okuyisisekelo: Lokhu kuzohlola ukuthi amazinga e-sodium (usawoti) egazini lakho aphansi noma ukuthi amazinga e-potassium akho aphezulu.
2. Ukuhlolwa Kokukhuthaza I-ACTH: Lolu vivinyo olubaluleke kakhulu. Kulokhu, inani elincane le-hormone ebizwa ngokuthi i-ACTH, ekhishwa ubuchopho bakho, linikezwa njengomjovo. Kumuntu ophilile, lo mjovo ubangela ukuthi izindlala ze-adrenal zikhiqize i-hormone eningi i-cortisol. Kodwa-ke, kumuntu onesifo sika-Addison, izindlala aziphenduli ngale ndlela. Lesi sifo siqinisekiswa ngokuthatha isampula yegazi bese kulinganiswa leli zinga le-cortisol.
Ngaphezu kwalokho, kungenziwa i-CT scan ukuze kuhlolwe ukutheleleka, umdlavuza, noma ukopha ezindlaleni ze-adrenal.
Okuyingozi kakhulu: Inkinga ye-Addisonian
Lesi yisigaba esiyingozi kakhulu nesizumayo sesifo sika-Addison. Izimpawu zivame ukuza kancane kancane, ngakho abanye abantu abazi nokuthi banaso lesi sifo. Kuleli qophelo, uma umzimba ungaphansi kokucindezeleka okukhulu, njengokugula okunye, ukuhlinzwa, noma ingozi, izimpawu zingaba zimbi kakhulu ngokuzumayo. Lokhu kubizwa ngokuthi inkinga ye-Addisonian .
Lesi yisimo esiphuthumayo sezokwelapha futhi singaholela ekufeni uma singelashwa.
Izimpawu zenkinga ye-Addisonian:
- Ubuhlungu obukhulu obungazelelwe emhlane, esiswini, noma emilenzeni.
- Ukuhlanza okukhulu kanye nohudo, okuholela ekuphelelweni amanzi emzimbeni.
- Ukushaqeka okubangelwa umfutho wegazi ophansi kakhulu.
- Ukulahlekelwa ukwazi.
- Umkhuhlane osheshayo kanye nobuthakathaka obukhulu.
Uma lezi zimpawu zivela,Isiguli kufanele siyiswe e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze ngokushesha.
Ukwelashwa kanye nokuphila okuvamile
Ungase wesabe ukuzwa ngesifo sika-Addison, kodwa izindaba ezinhle ukuthi kunezindlela zokwelapha eziphumelela kakhulu .
Lesi sifo sibangelwa izinhlobo ezimbili zama-hormone angekho emzimbeni. Ngakho-ke ukwelashwa ukunikeza lawo ma-hormone ngaphandle ngesimo samaphilisi.
- I-Hydrocortisone: Iphilisi le-steroid elithatha indawo ye-hormone i-cortisol.
- I-Fludrocortisone: Iphilisi elithatha indawo ye-hormone i-aldosterone.
Lomuthi kufanele uthathwe nsuku zonke, njengoba nje udokotela emyalile.
Into ebaluleke kakhulu ukungalokothi weqe umthamo owodwa wemithi. Ukuphuthelwa ngisho nomthamo owodwa kungaba yingozi.
Uma unesifo, umkhuhlane, noma uhlinzwa, udokotela wakho uzokwandisa umthamo walo muthi okwesikhashana ukuze avimbele inkinga ye-Addisonian.
Ngokwelashwa okufanele , umuntu onesifo sika-Addison angaphila impilo evamile nenempilo .
Umlayezo Wokuya Nawe Ekhaya
- Isifo sika-Addison yisimo lapho izindlala ze-adrenal zihluleka khona ukukhiqiza ama-hormone anele i-cortisol ne-aldosterone.
- Izimpawu eziyinhloko ukukhathala okuqhubekayo, ukwehla kwesisindo, umfutho wegazi ophansi, kanye nokuba mnyama kwesikhumba.
- Uma unalezi zimpawu, ungesabi futhi ubone udokotela ngokushesha.
- Nakuba lesi kuyisimo sokuphila konke, ungaphila impilo evamile ngokuthatha imithi yansuku zonke.
- Uma unesifo sika-Addison, gqoka njalo ikhadi noma isongo esichaza isimo sakho. Kungaba ukusindisa impilo yakho esimweni esiphuthumayo.
- Inkinga ye-Addisonian iyisimo esiphuthumayo esidinga ukwelashwa ngokushesha. Kubalulekile ukwazi izimpawu.
Isifo sika-Addison, ama-hormone, izindlala ze-adrenal, i-cortisol, i-aldosterone, ukukhathala okuqhubekayo, ukuba mnyama kwesikhumba, izindlala ze-adrenal, ukungasebenzi kahle kwe-adrenal, umfutho wegazi ophansi
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