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Gbã la, mina míakpɔe ɖa, nukatae ʋu metsina le ʋusɔgbɔdɔ me o?
Ne míagblɔe kpuie la, protein tɔxɛ aɖewo li siwo kpena ɖe míaƒe ʋu ŋu. Míeyɔa esiawo be " ʋumenugbagbeviɣidɔ ƒe nuwɔna ." Abe alesi ko aŋɔ hiã be woatsɔ alé anyikpewo ɖe wo nɔewo ŋu ne wole gli tum ene la, nenema ke ʋu ƒe sisi ƒe nu siawo le vevie be ʋu nadzudzɔ dodo. Ame si ŋu ʋusɔgbɔdɔ le la ƒe ʋumenugbagbeviɣidɔ siawo dometɔ ɖeka mebuna o.- Atike aɖe si woyɔna be Factor VIII mele amesiwo ŋu ʋusɔgbɔdɔ A le o.
- Atike aɖe si woyɔna be Factor IX mele amesiwo ŋu ʋusɔgbɔdɔ B le o.
Eyata nukae nye atike yeye sia si woyɔna be Qfitlia (fitusiran)?
Esia nye atike si wɔa dɔ le mɔ si wɔ nuku ŋutɔ nu. Míeƒo nu tso nyateƒe si wònye be ʋu hiã nane si woyɔna be thrombin hafi ʋu natsi la ŋu va yi. Le mía ŋutɔwo míaƒe ŋutilã me la, protein bubu aɖe hã li si kpɔa ŋusẽ ɖe thrombin sia ƒe wɔwɔ dzi, si fia be edzudzɔa thrombin geɖe ƒe wɔwɔ. Woyɔa esia be antithrombin .Bu eŋu ale. Ʋu ƒe sisi (thrombin) le wò ŋutilã me si kpena ɖe ŋuwò be wò ʋu natsi. Gake nu bubu aɖe hã li (antithrombin) si kpɔa ŋusẽ ɖe edzi hexea mɔ nɛ be megawɔa dɔ o. Le ʋusɔgbɔdɔ me la, nusi kpena ɖe ame ŋu (thrombin) ƒe wɔwɔme medea ame dzi le gɔmedzedzea me o. Eyata ne nusi xea mɔ na (antithrombin) wɔ dɔ nyuie la, ʋu ƒe sisi dzi ɖena kpɔtɔna wu. Nusi Qfitlia wɔna enye be eɖea antithrombin si xea mɔ nɛ ƒe agbɔsɔsɔ dzi kpɔtɔna. Emegbe woɖea mɔ na thrombin agbɔsɔsɔme si wò ŋutilã wɔna le dzɔdzɔme nu be wòawɔ dɔ nyuie evɔ womaxe mɔ nɛ o. Esia fia be ezãa ŋutilãa ŋutɔ ƒe ɖoɖo tsɔ dea ʋu ƒe sisi ƒe dzi ƒo, tsɔ wu be wòana ʋu ƒe sisi ƒe nusi bu na wò. Esiae nye atike gbãtɔ si ɖea ʋumenugbagbeviɣidɔ dzi kpɔtɔna si wozã le ʋusɔgbɔdɔ dada me.Mina míagaɖe vovototo si le atikewɔwɔmɔnu eve siawo dome la me.
Àte ŋu ase vovototo sia gɔme bɔbɔe tso kplɔ̃ si le ete la dzi.| Nɔnɔme si le ame ŋu | Atikewɔwɔ si wozãna le blema (Factor Replacement) . | Qfitlia (fitusiran) ƒe atikewɔwɔ |
|---|---|---|
| Dɔwɔwɔ ƒe ŋutete | Wotsɔa ʋumenugbagbeviɣidɔ si mele ŋutilãa me o la naa gotagome. | Eɖea antithrombin si xea mɔ na ʋu ƒe sisi dzi kpɔtɔna, eye wònana ŋutilãa te ŋu zãa eya ŋutɔ ƒe thrombin geɖe wu. |
| Alesi woana nu | Zi geɖe la, wodonɛ ɖe ʋuka me. | Le ŋutigbalẽa te (subcutaneous). |
| Xexlẽme | Ate ŋu ahiã zi geɖe le kwasiɖa me. | Zi ɖeka le ɣletia me alo ɣleti eve ɖesiaɖe (zi 6-12 le ƒea me). |
| Le amesiwo si mɔxenuwo le gome | Normal factor therapy mewɔa dɔ o, eye atikewɔwɔ tɔxɛ bubuwo (bypassing agents) hiã. | Woate ŋu azã atikewɔwɔ sia dzidzedzetɔe le amesiwo ŋu mɔxexeɖedɔlékuiwo (dɔlékui siwo tsi tre ɖe nusiwo gbɔ wòtso ŋu) le hã ŋu. |
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Check Availability →Ðe atike sia sɔ nam eye aleke mazãe?
Ne ʋusɔgbɔdɔ A alo B le ŋuwò eye nèxɔ wu ƒe 12 la, wò ɖɔkta ate ŋu abu eŋu nenye be atike sia sɔ na wò. Nu vevitɔe nye be woate ŋu azãe le amesiwo to mɔxenu (tsitretsitsi) vɛ na factor therapy va yi hã ŋu. Gake hafi nàdze atikewɔwɔ sia gɔme la, wò ɖɔkta awɔ ʋudodokpɔ geɖe . 1. Antithrombin ƒe agbɔsɔsɔ: Esia dzidzea antithrombin agbɔsɔsɔme si le wò ʋu me. Wonɔa te ɖe asixɔxɔ sia dzi dea dzesi Qfitlia ƒe agbɔsɔsɔme. 2. Aklã ƒe dɔwɔwɔ: Woléa ŋku ɖe wò aklã ŋu do ŋgɔ na atikewɔwɔ kple le ewɔwɔ me. Wodoa atike sia abe atike si wodona ɖe ŋutigbalẽa te ene (le ŋutigbalẽ te). Esia fia be wometsɔe de ʋuka me o. Wò alo dɔnɔdzikpɔla ate ŋu ana wò le aƒeme le hehexɔxɔ vɔ megbe. Wonanɛ le ƒodo, ata, alo abɔta ƒe megbe ƒe ŋutigbalẽ me. Ele be nàƒo asa na teƒe siwo abi alo lãɖeɖe le. Ne èle ʋusɔgbɔdɔ ƒe atike bubuwo zãm xoxo la, ahiã be nàdzudzɔ alo atrɔ wo le Qfitlia gɔmedzedze vɔ megbe. Wò ɖɔkta aɖe nya sia me na wò eme nakɔ. Mègadzudzɔ atike siwo nèzãna fifia nono alo dzudzɔ Qfitlia nono wò ɖɔkta ƒe aɖaŋuɖoɖo manɔmee gbeɖe o. Esia wɔwɔ ate ŋu ana ʋu nado le ŋuwò nadzi ɖe edzi.Ðe wòle be míanya nu gbegblẽ siwo dona tso eme hãa? Aleke míawɔ axe mɔ ɖe wo nu?
Abe atike ɖesiaɖe ene la, Qfitlia ate ŋu akpɔ nugbegblẽ aɖewo. Ele vevie be nànya nu tso wo ŋu eye nàwɔ afɔɖeɖewo atsɔ axe mɔ ɖe wo nu.- Ʋu ƒe sisi: Esi atike sia doa ʋu ƒe sisi ɖe ŋgɔ ta la, ƒã ŋutɔ be ʋu si melɔ̃ o nadzɔ ɖe ʋukawo me. Wò ɖɔkta akpɔ agbɔsɔsɔ si sɔ na wò antithrombin ƒe agbɔsɔsɔ be wòaɖe afɔku sia dzi akpɔtɔ.
- Aklã me dɔlékuiwo ƒe dzidziɖedzi: Ðewohĩ aklã me dɔlékuiwutikewo dzi ɖe edzi le ame aɖewo si . Esia tae ɖɔktawo léa ŋku ɖe aklã ƒe nɔnɔme ŋu edziedzi to ʋudodokpɔ me ɖo .
- Gallstones and Gallbladder Inflammation: Ne èkpɔ dzesiwo abe dɔgbo ƒe vevesese sesẽ, ʋuʋudedi, kple ʋuʋudedi ene zi ɖeka la, na wò ɖɔkta nanya enumake.
- Dɔlékuiwo: Afɔku sue aɖe le dɔlékuiwo xɔxɔ me le afisi wodoe ɖo. Eyata ele vevie be nàdo atike na wò nyuie ɣesiaɣi eye wòanɔ abe alesi wò ɖɔkta gblɔe ene. Dzadzɛnyenye ƒe mɔnu nyuiwo, abe asikɔklɔ enuenu ene hã le vevie.
Gbedasi si Wotsɔ Yi Aƒeme
- Qfitlia (fitusiran) nye ʋusɔgbɔdɔ A kple B ƒe atike yeye si wɔa dɔ le mɔ bubu nu.
- Esia wɔa dɔ to antithrombin, si xea mɔ na ʋu ƒe sisi ƒe agbɔsɔsɔ dzi ɖeɖe kpɔtɔ me, le esi teƒe be wòana ŋutilãa ƒe ʋu ƒe sisi ƒe akpa si le sue la le gota.
- Atike sia nyea atike si wodona ɖe ŋutigbalẽ te, ke menye ɖe ʋuka me o, eye zi geɖe la, womedonɛ edziedzi o, abe zi ɖeka le ɣletia me alo ɣleti eve ɖesiaɖe ene.
- Wò ɖɔkta akpɔe ɖa be atike sia sɔ na wò hã le ʋudodokpɔ zi geɖe megbe.
- Be nàƒo asa na nugbegblẽ le ame ŋu la, ele vevie be nàdo ʋu kpɔ (vevietɔ antithrombin kple aklã ƒe dɔwɔwɔ) edziedzi abe alesi wò ɖɔkta gblɔe ene.
- Ƒo asa na Qfitlia ƒe atikewɔwɔ dzudzɔ atikewɔlawo ƒe aɖaŋuɖoɖo manɔmee le susu aɖeke ta.
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