Ua hoʻonui ʻia anei ka nui o nā eosinophils, kahi ʻano o ke koko keʻokeʻo, i loko o kou kino? E kamaʻilio kākou e pili ana i ka Hypereosinophilic Syndrome!

Ke manaʻo nei ʻoe i kekahi manawa he hewa kekahi mea me kou kino, ke loaʻa mau nei iā ʻoe nā pilikia, akā ʻaʻole hiki iā ʻoe ke ʻike pono i ke ʻano o ia mea? Aia kekahi mau maʻi i kakaikahi loa a paʻakikī iki. I kēia lā e kamaʻilio mākou e pili ana i kekahi o ia ʻano maʻi. Ma kēia, aia ka piʻi nui ʻana o ka helu o nā eosinophils, kahi ʻano kūikawā o ke koko keʻokeʻo i loko o ko mākou kino.

He aha ka maʻi Hypereosinophilic?

I ka ʻōlelo maʻalahi, ʻo ka Hypereosinophilic Syndrome (HES) kahi maʻi kakaikahi e kū mai ana i ka wā e piʻi nui ai ka nui o nā eosinophils , kahi ʻano o ke koko keʻokeʻo i loko o ko mākou kino. I kēia manawa ke noʻonoʻo nei paha ʻoe i ke ʻano o kēia mau eosinophils.

E noʻonoʻo e like me kahi pā kaua. Aia nā ʻano koa like ʻole e pale aku i kēia pā kaua. Pēlā nō, aia nā ʻano koko keʻokeʻo like ʻole i loko o ko kākou koko e hakakā ana i nā germs a pale iā kākou mai nā maʻi. ʻO nā Eosinophils kekahi o ia mau koa kūikawā. ʻO kā lākou kuleana nui ka hakakā ʻana i nā parasites e komo i loko o ko kākou kino a e pane i ka wā e loaʻa ai nā maʻi allergies.

ʻO ka maʻamau, ʻo 5% a 7% o ka huina o nā keʻokeʻo koko keʻokeʻo i loko o ke koko o ke kanaka olakino nā eosinophils. ʻO ia hoʻi, aia ma waena o 100 a me 500 eosinophils no kēlā me kēia microliter o ke koko. Eia nō naʻe, ke loaʻa iā ʻoe kahi mea e like me ka maʻi allergy, hiki i kēia mau eosinophils ke hoʻonui iki. Kāhea mākou i kēlā ʻano he eosinophilia .

Eia nō naʻe, i loko o ka maʻi hypereosinophilic (HES), lilo kēia ʻano i kapa ʻia ʻo eosinophilia i mea koʻikoʻi, a hana ʻia ka hana ʻana o ka eosinophil i kahi wikiwiki, e hōʻiliʻili nui ana kēia mau cell i loko o ke koko a me nā ʻiʻo like ʻole o ke kino. Ke hoʻonui ʻia nā eosinophils ma kēia ʻano, hoʻomaka kēia mau cell e hōʻino i nā ʻōpū koʻikoʻi e like me ko mākou puʻuwai, nā māmā, ka ʻili, a me ka ʻōnaehana nerve. Inā ʻaʻole mālama pono ʻia, hiki i kēia ʻano ke hoʻoweliweli i ke ola. Akā ʻo ka nūhou maikaʻi , inā ʻike mua ʻia ka maʻi a hoʻomaka ʻia ka mālama kūpono, ʻoi aku ma mua o 80% o ka poʻe me HES e ola maikaʻi ana ʻoiai ʻelima mau makahiki ma hope o ka hōʻoia ʻana.

ʻO wai ka mea e loaʻa ana i ka hypereosinophilic syndrome (HES)?

He mea kākaʻikahi loa kēia ʻano maʻi i kapa ʻia ʻo HES. No laila, he paʻakikī i nā kauka ke ʻōlelo pololei i ka nui o ka poʻe i loaʻa i kēia maʻi. ʻOiai hiki i kekahi ke loaʻa i kēia maʻi, ʻoi aku ka maʻamau i ka poʻe ma waena o 20 a me 50 mau makahiki .

He aha ke kumu o ka hypereosinophilic syndrome (HES)?

ʻO kaʻoiaʻiʻo, i ka hapanui o nā hihia o HES, ʻaʻole i ʻike pono nā kānaka noiʻi i ke kumu o kēia piʻi koke ʻana o ka helu eosinophil. Eia naʻe, ua ʻike lākou i kekahi mau kūlana a i ʻole nā ​​​​kumu e hiki ke kōkua i kēia:

• Nā maʻi Myeloproliferative: He hui kēia o nā maʻi i hōʻike ʻia e ka hana nui ʻana o nā hunaola koko i loko o ko kākou iwi iwi. I ka ʻōlelo maʻalahi, ua like ia me ka hana nui ʻana o ka iwi iwi.
• Nā pae kiʻekiʻe o Interleukin-5: He protein kēia i hana ʻia e ko kākou mau hunaola koko keʻokeʻo. Ke hoʻonui ʻia kēia, hoʻoulu ʻia ka hana ʻana o nā eosinophils.
• ʻO kahi ʻano kūʻē i ka hoʻoilina e hoʻolalelale ai i ka ulu ʻana o nā cell: I kekahi manawa, hiki i kēia mau cell ke ulu me ka ʻole o ke kāohi ʻia ma muli o nā loli i nā genes.

He aha nā hōʻailona o HES?

ʻO ka hōʻailona maʻamau o HES he ʻulaʻula a he hives paha. Aia nā hōʻailona ʻē aʻe i kahi o ke kino i kiʻekiʻe ai nā pae eosinophil.

E noʻonoʻo e pili ana i kēia ʻano:

• Inā pilikia ka puʻuwai: Hiki iā ʻoe ke ʻike i nā hōʻailona e like me ka Congestive Heart Failure (kahi ʻano like me ka hāʻule ʻana o ka puʻuwai), Cardiomyopathy (nāwaliwali o ka ʻiʻo puʻuwai), Myocarditis (ka mumū o ka ʻiʻo puʻuwai), a i ʻole Pericardial Effusion (ka hōʻiliʻili ʻana o ka wai a puni ka puʻuwai).
• Inā pilikia nā māmā: Hiki iā ʻoe ke loaʻa i nā maʻi hanu luna pinepine, e like me ke anu a me ka maʻi flū, ke kuni, a me ka paʻakikī o ka hanu ʻana.

Eia kekahi, ʻike ʻia nā hōʻailona maʻamau e like me ka luhi, ke kuni, nā ʻeha kino, a me ka pohō kaumaha .

Pehea e ʻike ai nā kauka i ka maʻi hypereosinophilic (HES)?

Hiki ke lilo ka ʻike ʻana i ka HES i kahi hana paʻakikī. Hoʻohana pinepine nā kauka i kahi "kaʻina hana o ka hoʻopau ʻana," ʻo ia hoʻi ka hōʻoia ʻana ʻaʻohe mau kūlana ʻē aʻe e hiki ke hoʻoulu.

Eia kekahi laʻana, inā he mau ʻeha ʻili mau loa kou, e nānā mua paha kāu kauka i kekahi mau kūlana ʻili a kuhikuhi i ka lāʻau no lākou.

Inā hoʻomau kāu mau hōʻailona ma hope o kēia mau lāʻau lapaʻau, a laila hiki i kāu kauka ke hana i kahi hoʻāʻo koko e nānā i nā pae eosinophil kiʻekiʻe i loko o kou koko. Inā pili kāu mau hōʻailona i kahi pilikia ate, a ma hope o ka hoʻopau ʻana i nā kumu ʻē aʻe, hiki i kāu kauka ke hana i kahi hoʻāʻo koko hana ate . I kekahi manawa, pono paha kahi biopsy (lawe ʻana i kahi ʻāpana ʻiʻo) e hōʻoia i kahi hōʻailona o HES.

No ka mea, he manawa lōʻihi ka ʻike ʻana i kēia maʻi, hiki iā ʻoe ke maʻi no nā mahina, luhi, a hiki ʻole ke ʻike pono i ka mea e hana nei. Akā, he mea nui e hoʻomanawanui.

Pehea e mālama ai nā kauka i ka maʻi hypereosinophilic (HES)?

ʻO ka pahuhopu nui o nā kauka ke hoʻemi i nā pae kiʻekiʻe o nā eosinophils i loko o kou koko a me nā ʻiʻo. ʻO nā lāʻau lapaʻau maʻamau i hoʻohana ʻia no ka hoʻokō ʻana i kēia:

• Corticosteroids: He mau lāʻau anti-inflammatory ikaika kēia.
• Nā lāʻau lapaʻau Chemotherapy: Nā lāʻau i hāʻawi ʻia e pepehi i nā hunaola kanesa. Hoʻohana ʻia kēia mau mea i nā dosis haʻahaʻa e kāohi i nā hunaola eosinophil.

Eia kekahi, hoʻohana ʻia nā lāʻau lapaʻau i hoʻolālā ʻia e like me Imatinib a me nā monoclonal antibody therapies i kekahi manawa.

Hiki ke pale ʻia ka maʻi hypereosinophilic (HES)?

ʻO ka mea pōʻino, ʻoiai ʻaʻole ʻike ʻia ke kumu kikoʻī o ka hapa nui o nā hihia HES, he paʻakikī ke ʻōlelo kikoʻī e pili ana i ka pehea e pale aku ai.

Inā loaʻa iaʻu ka hypereosinophilic syndrome (HES), he aha kaʻu e manaʻo ai? (Holomua o ka maʻi)

ʻO ke ʻano o kou maʻi i ka wā e hiki mai ana, a i ʻole "prognosis," e pili ana i kou kūlana kikoʻī. No ka laʻana, inā ua hoʻokumu ʻia kāu HES e kahi mea kikoʻī, e like me ka maʻi iwi iwi, e kuhikuhi paha kāu kauka i kahi lāʻau lapaʻau i kuhikuhi ʻia i kēlā maʻi.

Eia nō naʻe, inā ʻaʻole hiki i kāu kauka ke ʻike i ke kumu o kou kūlana HES, e kālele ana ka lāʻau lapaʻau i ka kaohi ʻana i kāu mau hōʻailona. No ka laʻana, inā hoʻopilikia ka HES i kou mau māmā a loaʻa pinepine iā ʻoe nā maʻi, e hoʻāʻo ka lāʻau lapaʻau e kaohi i kēlā mau maʻi.

Ma keʻano laulā, ʻo ka wikiwiki o ka ʻike ʻia a me ka mālama ʻia ʻana o ka HES, ʻo ka liʻiliʻi o ka loaʻa ʻana o nā pilikia lōʻihi.

Pehea wau e mālama ai i koʻu olakino?

E like me kā mākou i ʻōlelo ai ma mua, mālama pinepine nā kauka i ka HES me nā corticosteroids a me ka chemotherapy. Hiki i kēia mau lāʻau ʻelua ke loaʻa nā hopena ʻaoʻao . No laila, e kamaʻilio me kāu kauka e pili ana i kēia mau hopena ʻaoʻao a me nā mea hiki iā ʻoe ke hana e hōʻemi i ko lākou hopena.

• E lawe i kāu mau lāʻau lapaʻau i ka manawa kūpono.
• E hahai i nā kuhikuhi a ke kauka.
• E ʻai i ka meaʻai kaulike.
• E ho'āʻo e hoʻomaha i ka hiki.
• E ikaika i ka noʻonoʻo.

Āhea wau e ʻike ai i kaʻu kauka?

Inā ua ʻike ʻia ʻoe me HES, a hoʻomau a ʻoi aʻe paha kou mau hōʻailona, ​​e ʻike koke i kāu kauka. Eia kekahi, e hōʻoia e hele i kāu mau manawa i hoʻonohonoho ʻia ma ke keʻena lapaʻau.

Āhea wau e hele ai i ka lumi pilikia?

Ua ʻike mākou he hiki i kahi maʻi i kapa ʻia ʻo hypereosinophilic syndrome (HES) ke hoʻopilikia i nā ʻano kino like ʻole, me ka puʻuwai. No laila, inā pilikia kou puʻuwai e HES, a ʻike ʻoe i nā hōʻailona e like me ka ʻeha koke o ka umauma, ka paʻa o ka umauma, ka nausea, a me ka hou ʻana , pono ʻoe e hele koke i ka lumi pilikia. He mau hōʻailona paha kēia o ka hōʻeha puʻuwai.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

No ka mea he maʻi laha ʻole ka HES, nui paha kāu mau nīnau e pili ana i ia mea. Eia kekahi mau nīnau hiki iā ʻoe ke nīnau e hoʻomaka ai:

• E ke kauka, he aha maoli kēia Hypereosinophilic Syndrome?
• No ke aha i hiki mai ai kēia iaʻu?
• Hiki ke mālama ʻia kēia?
• He aha nā lāʻau lapaʻau i loaʻa?
• He aha nā hopena ʻaoʻao o ka lāʻau lapaʻau?
• E hiki anei i kēia kūlana HES ke hoʻi hou mai?
• Hiki iaʻu ke ho'ōla loa ʻia?

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai (Leka Lawe-Home)

He maʻi laha ʻole ka maʻi Hypereosinophilic (HES) a he paʻakikī ke ʻike i kekahi manawa. Inā loaʻa iā ʻoe ka HES, ua maʻi paha ʻoe no nā mahina, e ʻeha ana i nā maʻi like ʻole, a ʻaʻole maikaʻi ke ʻano.

Akā ʻo ka nūhou maikaʻi, ke ʻike ʻia ʻoe me HES, aia nā lāʻau lapaʻau kūpono e loaʻa ana. Hiki ke hala kekahi mau mahina no kāu lāʻau lapaʻau e hōʻike i nā hopena, no laila e hoʻāʻo e hoʻomanawanui. Eia kekahi, inā pilikia ʻoe i ka hoʻoponopono ʻana i nā pilikia o kahi maʻi lōʻihi, e kamaʻilio me kāu kauka. Hiki iā lākou ke haʻi iā ʻoe e pili ana i nā papahana a me nā kumuwaiwai e hiki ke kōkua iā ʻoe. E hoʻomanaʻo, ʻaʻole ʻoe hoʻokahi!

ʻO ka Hypereosinophilic Syndrome, HES, Eosinophils, Eosinophilia, Nā Kelepona Koko Keʻokeʻo, Eosinophil, Eosinophilia, Nā Hōʻailona, ​​Lapaʻau