Yu rɛd blɔd sɛl dɛn dɔn big? (Macrocytosis) - Lɛ wi fɛn ɔut bɔt dis!

Yu dɔn ɛva luk pan blɔd tɛst ripɔt ɛn notis se yu rɛd blɔd sɛl dɛn big pas aw i fɔ bi (rɛd blɔd sɛl dɛn we dɔn big)? Ɔ yu dɔktɔ dɔn ɛva tɛl yu bɔt wan sik we dɛn kɔl “Macrocytosis”? Dis kin tan lɛk se yu de mek yu fred smɔl, bɔt nɔ wɔri. Makrosaytɔsis nɔto sik, na jɔs chenj na di rɛd blɔd sɛl.

Wetin na Makrosaytɔsis?

Fɔ tɔk am simpul wan, Makrosaytɔsis min se yu rɛd blɔd sɛl dɛn big pas aw i fɔ bi. Dɛn nɔ kin tek dis as sik, bɔt i kin bi sayn fɔ sɔntin we nɔ fayn na wi bɔdi. Dɛn kin no dis nɔmɔ we yu gɛt kɔmplit blɔd kɔnt (CBC)/ Ful Blɔd Kɔnt ( FBC ). כltu, dכkta dεn kin du dis `CBC` tεst fכ si aw wi bכdi in sεl dεm de wok εn aw dεn hεlty.

Di `CBC` ripɔt gɛt valyu we dɛn kɔl `MCV (Mean Corpuscular Volume)`. Dis na fɔ no di avrej saiz fɔ yu rɛd blɔd sɛl dɛn. if big man in `MCV` valyu pas 100 femtoliters (`100 fL`), wi kכl dat kכndishכn Makrosaytosis.

Bɔku tɛm, dis nɔto siriɔs prɔblɛm. Bɔt sɔntɛnde, dɛn rɛd blɔd sɛl ya we dɔn big nɔ kin gɛt di tin dɛn we dɛn nid. Dɔn, dɛn sɛl dɛn de nɔ kin ebul fɔ du dɛn men wok, we na fɔ kɛr ɔksijɛn go ɔlsay na di bɔdi. dis kכndyushכn dεn kכl am `Macrocytic Anemia` . If dɛn nɔ trit `Macrocytic Anemia` fayn, i kin mek yu gɛt siriɔs wɛlbɔdi prɔblɛm.

Aw dis sik kin kɔmɔn?

fכ tכk roughly, bitwin 2% εn 4% pan di pipul dεm na di wכl gεt Makrosaytosis. di mכtalman in pipul dεm, we na lεk 60%, gεt Makrosaytosis wit anemia.

Bɔt makrosaytɔsis we nɔ gɛt anemia kin apin mɔ pan yɔŋ pikin dɛn ɛn ol pipul dɛn.

Wetin na di sayn dɛm fɔ Makrosaytɔsis?

כl di tεm, di כnli sayn fכ makrosaytosis na di εlevεt MCV na di CBC ripot. Dis jɔs min se yu rɛd blɔd sɛl dɛn big. If di sayn dɛm apin, dɛn kin gɛt fɔ du wit di ɔndalayn kɔz fɔ di rɛd blɔd sɛl dɛm we dɔn big.

Fɔ ɛgzampul, if yu gɛt `Macrocytic Anemia`, yu kin gɛt sɔm sayn dɛm lɛk fɔ wik , taya, ɛn pale skin , we na kɔmɔn sayn dɛm fɔ anemia. Dɔn bak, if di tin we kin mek yu gɛt dis sik na bikɔs yu nɔ gɛt bɛtɛ tin fɔ it, yu kin gɛt sɔm sayn dɛn lɛk dayarɛa, yu nɔ go ebul fɔ mɛmba, ɛn yu nɔ go ebul fɔ balans .

Dat min se, bikɔs bɔku tin dɛn de we kin mek pɔsin gɛt makrosaytosis, di sayn dɛn bak kin difrɛn.

Wetin na di tin dɛn we kin mek pɔsin gɛt makrosaytɔsis?

Blɔd sɛl dɛn de kɔmɔt na wi bon mɛro. so, prכblεm we de fכ prodyuz rεd bכdi sεl dεm na dis bon mכro εn prכblεm we de fכ di strכkchכ fכ rεd bכdi sεl dεm kin mek Makrosaytosis. sכmtεm, if yu gεt tu mכch rεd bכdi sεl dεm we nכ machכ, we dεn kכl `rεtikulכsayt`, na yu bכdi, den di `MCV` valyu kin inkrεs bak. dis na biכs dεn `rεtikulכsayt dεm` ya big pas machכ rεd bכdi sεl dεm.

Sɔm pan di men tin dɛn we kin mek pɔsin gɛt makrosaytosis na:

Di tin dɛn we nɔ gɛt bɛtɛ tin fɔ it

di nyutriεnt dεm lεk vaytam in B12 εn fכlet (vitamin B9) na implεnt fכ wi bכdi fכ mek hεlty rεd bכdi sεl dεm. If yu nɔ gɛt dɛn tin ya we yu de it, ɔ if yu bɔdi nɔ ebul fɔ tek dɛn bikɔs ɔf sɔm sik, yu rɛd blɔd sɛl dɛn nɔ go gro fayn. if yu nכ gεt vaytam in B12 εn fכlet i kin mek yu gεt wan kכndyushכn we dεn kכl `Macrocytic Anemia`. Fɔ ɛgzampul, sɔm pipul dɛn nɔ kin it bɛtɛ grɛn vɛjitebul ɛn frut. Dis kin mek yu nɔ gɛt bɛtɛ folate. Dɔn bak, pipul dɛm wae nɔr de it pasmak kin gɛt vaytamɛn B12 dɛfisiɛns.

Sɔm mɛrɛsin dɛn

Makrosaytɔsis kin kam bak bay difrɛn mɛrɛsin dɛn. Di wan dɛn we kin bɔku pan dɛn na haydroksiyuria, we na wan mɛrɛsin we dɛn kin yuz fɔ mɛn siklɛt sik, difrɛn kayn kemotɛrapi mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn kansa, ɛn antiretroviral therapy (ART) we dɛn kin yuz fɔ mɛn pɔsin we gɛt HIV. If yu de tek ɛni wan pan dɛn mɛrɛsin ya, yu dɔktɔ go no bɔt dɛn.

Yuz rɔm

Fɔ drink pasmak na di men tin bak we kin mek pɔsin gɛt Makrosaytɔsis. Alkol de mek di bɔdi nɔ ebul fɔ tek di tin dɛn we i nid, mɔ di wan dɛn we i nid fɔ mek di rɛd blɔd sɛl dɛn we gɛt wɛlbɔdi.

Liva sik

Makrosaytɔsis kin bi sayn bak fɔ di liva sik. Bɔrku tɛm, liva sik kin gɛt fɔ du wit fɔ drink rɔm, bɔt nɔto ɔltɛm. Bɔt, liva sik kin apin bak fɔ ɔda rizin dɛn.

Ɛmolaytik anemia

insay wan kכndyushכn we dεn kכl ``Hemolytic anemia,'' yu rεd bכdi sεl dεm de day bifo tεm bikoz fכ wan כndalayn kכndyushכn. we dis apin, yu bכdi de rilis ``rεtikulכsayt dεm,'' (immature rεd bכdi sεl dεm) insay di bכdi fכ mek di sכt. Dɛn rɛd blɔd sɛl ya we nɔ machɔ nɔ ebul fɔ kɛr ɔksijɛn lɛk machɔ rɛd blɔd sɛl dɛn.

Blɔd we de kɔmɔt pasmak

If yu lɔs bɔku blɔd, ilɛksɛf na aksidɛnt, ɔpreshɔn, ɔ ɔda tin, yu bɔdi go ad rɛtiklɔsayt dɛn to yu blɔd fɔ mek di blɔd we yu lɔs. Jɔs lɛk aw i kin gɛt ɛmolaytik anemia, di sɛl dɛn we nɔ machɔ kin go insay di blɔd bifo tɛm.

Maylodysplastik sindrom we gɛt di sik

Dis na wan kayn kansa we kin kam na di bon mכro. dis kכndyushכn de mek di bon mכro nכ de mek hεlty rεd bכdi sεl dεm.

Di sik we dɛn kɔl haypotayroyd

Makrosaytosis kin apin bak pan pipul dɛm wae gɛt haypotayroydism, we na wan tayroyd gland we nɔ de wok fayn. I kin apin wit ɔ atɔl anemia.

sכmtεm, dεn kin fכnshכn nכ klia kכz fכ makrosaytosis, spεshal wan if yu nכ gεt makrosaytosis we nכ gεt anemia.

Aw yu go no if yu gɛt makrosaytɔsis?

As wi bin dɔn tɔk, makrosaytɔsis na wɔd we de tɔk bɔt di rɛd blɔd sɛl dɛn we dɔn big, nɔto ɔfishal sik. If di MCV valyu na yu CBC ripɔt pas 100 fL, dat min se yu rɛd blɔd sɛl dɛn big pas aw i fɔ bi.

Sɔntɛnde, dɔktɔ dɛn kin gɛs wetin kin mek pɔsin gɛt Makrosaytɔsis bay aw di sik rili bad. fכ egzampl, if di MCV rili hכy (arawnd 110 – 115 fL), i kin bi sayn fכ mכr siriכs makrosaytik anemia, lεk megaloblastic anemia.

Tεst dεm fכ fכnshכn di kכz fכ makrosaytosis

If yu dɔktɔ de wɔri bɔt yu rɛd blɔd sɛl dɛn we dɔn big, i go aks yu kwɛstyɔn dɛn fɔ no wetin mek yu gɛt am. I kin aks bɔt yu mɛrɛsin istri, di mɛrɛsin dɛn we yu de tek, di it we yu de it, ɛn di we aw yu de drink rɔm . Apat frɔm dat, i kin du sɔm ɔda tɛst dɛn bak:

• Pɛriferal blɔd smyuɛl:Dis min se yu fɔ tek wan sɛmpul pan yu blɔd ɛn luk am ɔnda maykroskɔp fɔ si if ɛnitin de we nɔ fayn we go de mek yu gɛt Makrosaytɔsis, lɛk prɔblɛm wit di rɛd blɔd sɛl dɛn we de gro.
• Vitamin B12 εn folate lεvεl tεst: If di bכdi lεvεl fכ vaytam in B12 כ folate lכw, dat min se di nyutrishכn dεm we nכ de gεt di nyutriεnt dεm we i nid fכ fכm rεd bכdi sεl dεm fayn fayn wan.
• rεtikulכsayt kכnt: Dis tεst de mכsu di nכmba fכ di rεd bכdi sεl dεm we nכ machכ na yu blכd sεmpl. Dis kin ɛp fɔ no if na dis kin mek yu gɛt ay MCV.
• Liva fכnshכn tεst: Dis de tεst aw yu liva de wok fayn fכ abzכp di nyutriεnt dεm we yu nid fכ mek hεlty rεd blכd sεl dεm.
• Bone marrow biopsy: Dɛn kin du dis tɛst if yu dɔktɔ tink se yu gɛt wan sik we de ambɔg yu rɛd blɔd sɛl. Dis min se yu fɔ tek smɔl smɔl pan yu bon mɛrɔ ɛn chɛk di sɛl dɛn ɔnda maykroskɔp fɔ si if ɛnitin de we nɔ fayn.

Aw dɛn kin trit Makrosaytɔsis?

If yu nɔ gɛt ɛni sayn fɔ lɛ yu nɔ gɛt blɔd, ɛn yu tɛst rizɔlt nɔ sho ɛni ɔda tin we nɔ fayn, yu nɔ go nid ɛni tritmɛnt. If nɔto dat, di tritmɛnt go dipen pan wetin mek yu gɛt bɔku bɔku rɛd blɔd sɛl.

• If yu makrosaytɔsis na bikɔs yu nɔ gɛt bɛtɛ tin fɔ it, yu go nid fɔ chenj di it we yu de it ɔ tek vaytamɛn sɔpɔtmɛnt .
• If di prɔblɛm na wit wan mɛrɛsin we yu de tek, yu dɔktɔ go ebul fɔ chenj di doz ɔ gi yu ɔda mɛrɛsin .
• If yu gɛt siriɔs anemia wit makrosaytɔsis, yu kin nid fɔ transfyushɔn blɔd .

Di tin we impɔtant pas ɔl na fɔ fala di tritmɛnt plan we yu dɔktɔ gi yu ɛksaktɔli, ilɛk wetin mek yu makrosaytɔsis.

Yu tink se dɛn kin mɛn Makrosaytɔsis?

bכku tεm, makrosaytosis go rivεs insεf we dεn trit di כndalayn kכz. Aks yu dɔktɔ aw di tritmɛnt go afɛkt yu wɛlbɔdi.

Aw fɔ ridyus di risk fɔ mek yu gɛt makrosaytɔsis?

Wi nɔ go ebul fɔ stɔp ɔltin we kin mek yu gɛt makrosaytɔsis. Bɔt wi kin ridyus di prɔblɛm we wi gɛt bay we wi de du tin dɛn we go mek wi gɛt wɛlbɔdi. Fɔ ɛgzampul:

• If yu ad it dɛn we gɛt vaytamɛn B12 ɛn folate – fish, dairy prodakt, eg , lif grɛn, ɛn fɔtifayt siriɔs – to yu it kin ridyus di risk fɔ gɛt makrosaytik anemia.
• I rili impɔtant fɔ lɛ yu nɔ drink rɔm .
• Dɔn bak, nɔ skip fɔ du blɔd tɛst ɛvri ia. Bɔku tɛm dɛn kin si makrosaytɔsis bay we dɛn de du blɔd tɛst ɔltɛm. If yu no di sik kwik kwik wan ɛn trit am, dat kin mek yu nɔr wɔs.

Wetin kin apin if dɛn nɔ trit makrosaytɔsis?

Na dɔktɔ nɔmɔ go ebul fɔ no if yu Makrosaytɔsis na sɔntin we yu fɔ wɔri bɔt. If yu gɛt Makrosaytɔsis wit anemia, i impɔtant fɔ go to tritmɛnt. If dɛn nɔ trit am, Macrocytic Anemia kin mek yu gɛt siriɔs wɛlbɔdi prɔblɛm.

Wetin a fɔ aks di dɔktɔ?

If yu kam fɔ no se yu rɛd blɔd sɛl dɛn big pas aw i fɔ bi, fala yu dɔktɔ in advays bɔt wetin fɔ du. Yu kin aks kwɛstyɔn dɛn lɛk:

• A fɔ wɔri bɔt mi ay MCV?
• Us tɛst dɛn a go nid fɔ no di kɔz fɔ makrosaytɔsis?
• A go nid fɔ trit di tin we mek mi rɛd blɔd sɛl dɛn dɔn big?
• Us chenj dεm na layf stεyl a kin mek fכ mεnεj dis Makrosaytosis kכndishכn?

Fɔ dɔn, mɛmba (Take-Home Message) .

Makrosaytɔsis ɔ wan ay MCV nɔto ɔltɛm na sɔntin we kin mek pɔsin wɔri. So nɔ ala if yu CBC ripɔt sho dɛn valyu ya. Gɛt yu dɔktɔ in gayd fɔ aw fɔ ɛksplen yu rizɔlt. Dipen pan yu rizulyt, yu dɔktɔ kin tɛl yu fɔ chenj di it ɔ fɔ tek vaytamɛn. Nɔ fred fɔ aks aw yu tritmɛnt go afɛkt yu blɔd sɛl ɛn ɔl yu wɛlbɔdi. Fɔ gɛt wɛlbɔdi na di tin we impɔtant pas ɔl!