Yu gɛt dɛn sik ya bak? Sɔntɛm dis na Pellagra!

Sɔntɛnde yu kin fil lɛk se yu nɔ gɛt ɛnaji, yu kin gɛt bɛlɛ prɔblɛm ɔltɛm, sɔm tɛm dɛn kin gɛt dayarɛa? Nɔto dat nɔmɔ, bɔt yu gɛt prɔblɛm dɛn bak na yu skin, strenj sayn dɛn, ɛn ɔda tin dɛn? Dɛn tin ya kin rili bi sayn fɔ difrɛn sik dɛn. Bɔt, tide wi go tɔk bɔt wan difrɛn kɔndishɔn smɔl we kin kam togɛda sɔntɛnde. Dat na wan sik we dɛn kɔl pellagra .

Wetin na Pɛlagra?

Fɔ tɔk am simpul wan, Pɛlagra na sik we pɔsin kin gɛt we i nɔ gɛt wan vaytamɛn we dɛn kɔl niacin , we dɛn kin kɔl bak vaytamɛn B3 . Dis na wan kayn pɔsin bak we nɔ de it fayn. Spɛshal wan, na wan maykronutriɛnt dɛfisiɛns. Niacin impɔtant fɔ mek di sɛl dɛn na wi bɔdi wok. So we i smɔl, di tin dɛn we i kin du kin sho as sayn dɛn ɔlsay na wi bɔdi, mɔ na say dɛn lɛk di skin, mɔt, intestinal, ɛn bren. If dɛn nɔ trit am fayn, i kin mek di nervɔs sistɛm pwɛl fɔ ɔltɛm ɛn sɔntɛnde i kin ivin day. Naw yu kin de wɔnda if ɔlman kin gɛt dis. Bɔrku tɛm, pɔrsin wae de it fayn fayn it kin gɛt di niacin we i nid. Bɔt, praymari pellagra – we kin kɔmɔt frɔm we dɛn nɔ gɛt niacin na di it – stil na big prɔblɛm na say dɛn we po, we nɔ gɛt it. Bɔt na divɛlop kɔntri dɛn lɛk Sri Lanka, bɔku tɛm, di niacin we nɔ de na di bɔdi kin bi sɛkɔn tin to ɔda tin dɛn we kin mek pɔsin gɛt sik. Dat min se ɔda sik stet ɔ tin dɛn we de mek wi bɔdi nɔ ebul fɔ tek ɔ yuz niacin fayn fayn wan.

Wetin na Niacin? Wetin mek wi nid am?

Wi bɔdi de yuz niacin fɔ chenj di kalori dɛn we de insay di it we wi de it to ɛnaji. Tink bɔt di it we wi de it as di petrol we de gi wi motoka pawa. Fɔ mek da petrol de rɔn, dɛn nid fɔ rifin am fayn fayn wan. Na dat niacin de du. di niacin we wi kin gεt frכm di it we wi de it de abzכp insay wi bכdi in tisu dεm tru wi sכmכl intestכn. Na de, i kin bi wan kɔɛnzym we dɛn kɔl Nicotinamide Adenine Dinucleotide (NAD) . dis NAD de εp mכr dan 400 εnzym dεm na wi bכdi fכ wok. Fɔ tɔk am simpul wan, dis NAD na di men tin we de ɛp wi bɔdi in sɛl dɛn fɔ mek ɛnaji (dɛn kin kɔl am bak Adenosine Triphosphate (ATP) ). apat frכm dat, NAD de kכntribyut to plεnti imכtant wok dεm, lεk fכ ripa DNA εn kכmyunikeshn bitwin sεl dεm.

Aw niacin we nɔ gɛt bɛtɛ tin kin afɛkt mi bɔdi?

biכs NAD na di men tin we de gi enεji to di sεl dεm, we i dכn dכn, i fכs afekt di sistεm dεm we nid di εnεji mכst כ we de divayd kwik kwik wan. Dat min se yu skin, di layn we de na yu bɛlɛ (frɔm yu mɔt to yu intestinal), ɛn yu bren. Dɔktɔ dɛn kin kɔl di men sayn dɛm fɔ pellagra di "3 Ds":Dayarɛa, dɛmatitis, ɛn dimɛnshɔn. Sɔm kin ivin ad wan nɔmba 4 "D": day . If dɛn nɔ trit am fɔ lɔng lɔng tɛm, i kin day.

1. Dayarɛa (Gastrointestinal mucositis) .

Dayarɛa kin apin we di layn na yu intestinal (mucosa) nɔ de rigenera fayn fayn wan. Tink bɔt am lɛk sɔntin we de protɛkt yu insay yu insay. We i dɔn go, yu insay nɔ kin ebul fɔ dayjɛst it fayn ɔ protɛkt insɛf frɔm infɛkshɔn ɔ injuri. Dis kin mek yu kɔntinyu fɔ inflamɛns frɔm yu mɔt to yu insay. Dis kin mek yu gɛt sɔm sayn dɛn lɛk bɛlɛ pen, yu nɔ kin it fayn, yu mɔt kin gɛt wund, ɛn yu tɔŋ kin rɛd ɛn swel .

2. Dɛmatitis (Skin fotosɛnsitiviti) .

Pɛlagra na wan patikyula kayn sik we de ambɔg di skin, mɔ di fes, nɛk, an, leg, an, ɛn fut, we de na di san. We di sɛl dɛn nɔ gɛt pawa igen, di sɛl dɛn na di skin kin rili fil bad we di san de shayn. Fɔs, di skin kin tɔn rɛd ɛn i kin tan lɛk se dɛn dɔn bɔn am wit san. Leta, di say dɛn kin rɔf, dɛn kin gɛt skel, ɛn sɔntɛnde blak (hyper-pigmented) plek dɛn kin apia. Wan pan de mak dɛm fɔ dis sik na wan dak band rawnd di nɛk. Dɛn kɔl am "Casal in kɔla." Dɛn gi dis in nem to di dɔktɔ we nem Dɔn Gaspa Kasal, we bin fɔs no di sik pan Spanish pipul dɛn we de wok na fam insay 1735.

3. Dimɛnshɔn (Bren ɛn nerve damej) .

Pɛlagra na wan sik we de ambɔg di wan ol bɔdi. Bikɔs ɔl di sɛl dɛn na di bɔdi kin lɔs di ɛnaji we i nid fɔ du in wok, i kin dɔn afɛkt di bren ɛn di nervɔs sistɛm. Di fɔs sayn dɛm nɔr kin rili klia. Yu kin jɔs fil lɛk se yu taya, yu nɔ bisin bɔt ɔda pipul dɛn, ɛn i nɔ kin izi fɔ yu fɔ pe atɛnshɔn . Ɔ yu kin gɛt sɔm sayn dɛm lɛk fɔ wɔri ɛn pwɛl hat . As tɛm de go, dɛn sik ya kin go bifo te dɛn kɔnfyus ɛn mek dɛn nɔ no wetin fɔ du . If yu gɛt siriɔs prɔblɛm, yu kin gɛt dis maynia sik fɔ ɔltɛm, ɛn yu kin gɛt prɔblɛm wit yu nyurolɔjik lɛk aw i nɔ kin ebul fɔ balans ɛn waka, yu mɔsul dɛn kin shek shek, ɛn yu kin shek .

Usay dɛn kin si Pɛlagra mɔ?

Frɔm trade trade, dɛn dɔn si pellagra pan po pipul dɛn ɔlsay na di wɔl, na kɔntri dɛn lɛk Yurop, Afrika, Eshia, ɛn Sawt Amɛrika. Bɔku tɛm dɛn dɔn si am pan pipul dɛn we nɔ de it bɛtɛ tin fɔ it. Ɛspɛshali pan di wan dɛn we nɔ bin gɛt bɔku prɔtin ɛn we bin de it kɔn. dis na biכs niacin nid fכ mek di bכdi tek di protin εn amino asid dεm fayn fayn wan. pan ɔl we kɔn gɛt niacin, i de insay "bound" fכm we wi bɔdi nɔ kin ebul fɔ absɔb izi wan.

Na Sɛntral ɛn Sawt Amɛrika, frɔm trade tradeWe dɛn de mek tɔti wit kɔn , dɛn kin sok di kɔn fɔ wan nɛt insay laym wata. dis prכsεs de rilis di niacin insay di kכn εn mek i abzכb mכr. Na dat mek pellagra nɔ kin bɔku na dɛn rijyɔn dɛn de.

Naw, Pellagra nɔ bɔku na di divɛlɔp Wɛstinian kɔntri dɛn lɛk Amɛrika. Dis na bikɔs ɔf di fɔtifikeshɔn fɔ bred ɛn rays wit niacin. Bɔt dɛn stil de si praymari Pɛlagra na di rijyɔn dɛn we nɔ de divɛlɔp bɛtɛ na di wɔl, mɔ pan trayb pipul dɛn we de it mays as dɛn men it. Dis sik stil de na India, Chaena, ɛn sɔm pat dɛn na Afrika. Pan ɔl we praymari Pɛlagra nɔ kin bɔku na kɔntri dɛn lɛk Sri Lanka, wi fɔ wɔri bɔt Pɛlagra we sɛkɔndari kɔz kin mek .

Wetin na di sayn dɛm fɔ Pellagra?

Na sɔm kɔmɔn sayn dɛm fɔ pellagra:

• Dayrɛa we nɔ de dɔn , sɔntɛnde i kin gɛt blɔd.
• Bɛlɛ pen ɛn nɔ de it fayn .
• I nɔ kin want fɔ it igen , i kin nɔs , ɛn i kin vɔmit .
• Eczema rash wit it ɔ pen na di skin .
• Mɔt sos ɛn wan rɛd, swel tɔng.
• Taya pasmak, wik, ɛn taya.
• Mud swing, pwɛl hat.
• di simptom dεm na di nεv sεstem - fכ egzampl, di limb dεm de shek εn sכmtεm sכmtεm.
• Delirium ɛn dis maynia sik.

Wetin na di tin dɛn we kin mek pɔsin gɛt Pɛlagra?

Di men tin we kin mek i apin na di it we nɔ gɛt bɔku niacin. Wi kin gɛt vaytamɛn B3 (niacin) frɔm difrɛn it dɛn. Bɔt pipul dɛn we nɔ kin it bɛtɛ tin fɔ it kin gɛt sɔm tin dɛn we de ɛp dɛn fɔ it. Pɛlagra kin divɛlɔp bak bikɔs ɔf sɛkɔndari kɔz dɛm . Dat min se ɔda wɛlbɔdi prɔblɛm dɛn we de mek yu bɔdi nɔ ebul fɔ tek ɔ yuz niacin fayn fayn wan. Sɔm ɛgzampul dɛn na:

• di sik dεm we de na di gεstכ intestinal we de mek i nכ de sכp di bכdi - fכ egzampl , Inflammatory Bowel Disease (IBD) כSirosis na di liva.
• Disɔda fɔ yuz rɔm: If pɔsin drink pasmak, i kin pwɛl di ɔgan dɛn lɛk di liva ɛn i kin mek di bɔdi nɔ ebul fɔ tek tin dɛn lɛk niacin. Dis kin mek i nɔ gɛt bɛtɛ it.
• Gastric bypass surgery: Afta sɔm ɔpreshɔn fɔ fat, di intestinal mucosa kin pwɛl, we kin mek i nɔ gɛt difrɛn maykronutriɛnt dɛn, inklud niacin.
• Iron deficiency anemia: Di bɔdi nid ayɔn bak fɔ chenj ɛn yuz niacin.
• Hartnup sik: Dis na sik we pɔsin kin gɛt we i kam pan jɛnɛtiks. I de mek di bɔdi nɔ ebul fɔ tek di amino asid dɛn. Dɛn amino asid ya impɔtant fɔ mek vaytamɛn dɛn.
• Carcinoid syndrome: Insay dis, di prodakshכn fכ niacin we di kεnsar sεl dεm de mek de rεdכks.
• Sɔm mɛrɛsin dɛn: Sɔm mɛrɛsin dɛn, mɔ di mɛrɛsin dɛn we de mek pɔsin nɔ spasmodik ɛn di mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn pipul dɛn we gɛt kemotɛrapi, kin ambɔg di we aw niacin de wok.
• HIV infεkshכn: HIV infεkshכn de mek di niacin lεvεl dεm na di bכdi dכn.

Aw dɛn kin no se pɔsin gɛt Pɛlagra?

We yu go to dɔktɔ, i go chɛk yu ɛn aks yu bɔt di sik dɛn we yu gɛt, yu mɛrɛsin istri, ɛn di tin dɛn we yu de it. If dɛn sɔprayz se dɛn gɛt pellagra, dɛn kin du urine test fɔ kɔnfirm di diagnosis. di lεvεl dεm fכ sכm kεmεkal dεm na yu urine kin tεl yu if yu gεt inof niacin na yu bכdi. Yu dɔktɔ kin gi yu niacin supamakit bak fɔ si if dɛn kin ɛp yu. Dat na wan we fɔ no di sik.

Wetin na di tritmɛnt dɛm fɔ Pellagra?

Pɛlagra kin kam bikɔs i nɔ gɛt bɛtɛ niacin ɔ vaytamɛn B3. So, di bɛst tritmɛnt fɔ am na fɔ ful-ɔp di bɔdi wit di tin we nɔ de. Dat min se yu fɔ gi niacin supamakit. Bɔrku pipul kin bigin fɔ wɛl kwik wans dɛn bigin fɔ tek dɛn tin ya. Bɔt dɛn kin nid ɔda tritmɛnt fɔ tin dɛn lɛk skin lɛsin ɛn mɔt ɔlsa.

Di tin we impɔtant pas ɔl na dat if yu gɛt pellagra bikɔs ɔf sɛkɔndari kɔz, dat na ɔda sik, den yu nid fɔ trit da ɔndalayn sik de fayn fayn wan bak.

Ɛni bad tin de we kin apin to di tritmɛnt?

If yu tek di mɛrɛsin lɛk aw yu dɔktɔ tɛl yu, bɔku tɛm, di niacin supamakit nɔ kin mek yu gɛt ɛni big big sayd ɛfɛkt. Bɔt if yu tek di mɛrɛsin pasmak, sɔm sayd ɛfɛkt dɛn kin apin. Bɔt, pɔsin we nɔ gɛt bɛtɛ tin na in bɔdi nɔ go izi fɔ tek am pasmak. If dat apin, dɛn tin ya kin apin:

• Skin we de flash.
• It ɛn ɛkzema rash.
• Bloating ɛn indigest.
• Ed we de at ɛn diziz.

Aw fɔ mek yu nɔ gɛt Pɛlagra?

Fɔ it tin dɛn we balans na di simpul we fɔ mek yu gɛt gud it. If di it dɛn we yu kin pik nɔ bɔku, it dɛn we gɛt bɔku bɔku tin dɛn fɔ it ɛn tin dɛn we yu kin it kin ɛp. Na lɛk 15 miligram niacin fɔ wan de na inof fɔ big pɔsin we gɛt wɛlbɔdi. dis amount kin kכmכt frכm wan B-kכmpleks vaytam in supliment. Sɔm pan di it dɛn we gɛt bɔku niacin na:

• Bif liva
• Bitrut (Bit) .
• Brewer in yist
• Bred ɛn siriɔs tin dɛn we dɛn dɔn ɛnrich
• Fish we gɛt ɔyl, lɛk salmɔn ɛn tuna
• Pinat dɛn we dɛn kin yuz fɔ mek tin dɛn
• Pɛtetɛ
• Pɔltri dɛn
• Res
• Sanflawa sid dɛn
• Spaghetti sos we dɛn kin mek

If yu gɛt wan sik wae de mɛk yu gɛt plɛnti sik wae de mek yu gɛt pellagra, tɔk to yu dɔktɔ bɔt aw fɔ avɔyd am fɔ lɔng tɛm. Dis kin min fɔ chenj di tin dɛn we yu de it, di tin dɛn we yu de it, ɔ di mɛrɛsin dɛn we yu de tek.

Aw lɔng i kin tek fɔ mek yu wɛl pan Pellagra?

We yu bigin fɔ tek niacin supamakit, bɔku pipul dɛn kin bigin fɔ fil fayn insay sɔm dez. Di dijestiv simptom dɛm (lɛk dayarɛa) kin bɛtɛ fɔs , bɔku tɛm insay di fɔs wik. Di skin ɛn mɔt sos kin tek tu wiks fɔ wɛl. Sɔm siriɔs kes kin tek lɔng tɛm. Bɔrku nerve damej ɛn dis maynia sik kin nɔr kin ebul fɔ chenj. Fɔ mek yu nɔ gɛt mɔ praymari pellagra, dɔktɔ dɛn kin se yu fɔ it tin dɛn we balans. Bɔku tɛm, we pɔsin nɔ gɛt niacin, i kin go wit ɔda maykronutriɛnt dɛn we nɔ gɛt bɛtɛ tin fɔ it. Yu kin kɔrɛkt ɔl dɛn tin ya if yu it gud it. Fɔ trit sɛkɔndari pellagra kin bi smɔl mɔ kɔmplikɛt. Pan ɔl we supamakit kin ɛp, if di bɔdi nɔ ebul fɔ mɛtabolayz niacin fayn fayn wan, dat ɛp nɔ kin inof. Insay dɛn kayn tin ya, fɔ wɛl kin dipen pan fɔ no ɛn trit di ɔndalayn kɔndishɔn we mek di pellagra. Dis kin tek lɔng tɛm, i kin dipen pan di sik.

Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .

Pan ɔl we dɛn dɔn pul di praymar pellagra bɔku pan di divɛlɔp kɔntri dɛn, i stil de pan po pipul dɛn we nɔ gɛt bɛtɛ tin fɔ it. Insay kɔntri dɛm lɛk wi yon, sɛkɔndari niacin dɛfisiɛns stil de bi risk bikɔs ɔf yus rɔm ɛn sɔm mɛdikal kɔndishɔn dɛm (espɛshali di wan dɛm we de ambɔg di nyutriɛnt absɔpshɔn).

Di tin we impɔtant pas ɔl na fɔ mɛmba se pan ɔl we di it kin bigin wit it, i kin dɔn insay di bɔdi.Bɔku tin dɛn we de insay yu bɔdi nid fɔ de wok fayn fayn wan. If yu gɛt ɛni sayn we de sho se sɔntin nɔ rayt, mɔ if yu gɛt prɔblɛm wit yu dijestiv sistɛm, mek shɔ se yu go to dɔktɔ. Ivin if yu nɔ gɛt bɛtɛ vaytamɛn, dat kin rili afɛkt yu wɛlbɔdi. So, it fayn it, liv fayn layf, ɛn go to dɔktɔ kwik kwik wan if yu gɛt ɛni prɔblɛm.

Pɛlagra, niacin, vaytamɛn B3, nɔ gɛt bɛtɛ tin fɔ it, sik dɛn na di skin, dayarɛa, dimɛnshɔn