I taksa defence system, chu chu immune system a chak loh chuan eng nge thleng ang? Very simple, i damlo tan fo thin. Taksain natna hrik a do theihna a tlahniam a. IVIG hi doctor-te’n heng natna vei te tanpui nan damdawi bik a ni. He hming hi i hre tawh mai thei. Chuvangin vawiin hian engkim hi awlsam tak leh friendly takin sawi ila.
A awlsam zawngin IVIg chu eng nge ni?
IVIg awmzia kimchang chu Intravenous Immunoglobulin tih a ni. Intravenous tih awmzia chu "vein kaltlangin" tihna a ni. Immunoglobulin hi kan thisena protein chi khat bik a ni a , natna dotu a ni . Heng antibodies te hi kan ti bawk .
Chuvangin, IVIg enkawlnaah chuan heng antibodies concentration pakhat, mi hrisel thisen atanga lakchhuah te hi vein kaltlangin immune system chak lo tak nei taksaah pek a ni. A awlsam zawngin, i taksaah natna do turin sipai sipai tam zawk pek ang mai a ni.
He enkawlna hi damdawi dang (entir nan, immunosuppressants , corticosteroids, emaw biologic drugs) aiah pek a ni \hin. Mi thenkhat chuan heng damdawi te nen hian IVIg pawh an dawng thei bawk. Hei hi i doctor-in a ruat a ni.
IVIg treatment hi eng condition nge pek a nih?
IVIg treatment hi immune system tichhe thei natna enkawl nan an hmang fo thin. I immune system a thawk tha lo a, chu chu antibody a siam tlem tihna a nih chuan bacteria infection i vei theihna a sang zawk tihna a ni. IVIg hian chu gap chu a luah khat a, infection lakah a venghim bawk.
A hnuaia table-ah hian IVIg therapy hman dan tlangpui thenkhat tarlan a ni.
| Dinhmun | IVIg-in a \anpui dan |
|---|---|
| Immune tlakchhamna - e.g. Immune Thrombocytopenia (ITP) a awm thei lo a ni. | Taksa ngei pawh hian thisen platelet tihchhiat a veng a, thisen chhuah thunun nan a pui a ni. |
| Kawasaki natna a ni | Thinlung thisen kalna kawngte chhiatna a tiziaawm a, a bik takin naupangte zinga he natna hi a tihchhiat a ni. |
| Guillain-Barré natna a ni | Immune system hian nerve a beih avanga chak lohna leh hnathawh that lohna chu a thunun a ni. |
| Autoimmune natna - e.g. Lupus, Polymyositis tih a ni | Taksa mahni cell (red blood cells, muscle cells) tihchhiatna a thunun. |
| Neurological natna - e.g. Myasthenia gravis, Multiple Sclerosis, Peripheral Neuropathy te a awm bawk | Nervous system chhiatna leh hnathawh that lohna control nan a pui thin. |
| Bone marrow transplant hnuah | Taksa invenna a chak lo hle laiin pawn lam natna laka invenna a pe a ni. |
Engtin nge he enkawlna hi tih a nih?
Hei hi thil pawimawh tak a ni. He tui Immunoglobulin an tih hi thisen petu hrisel tak takte thisen plasma atanga lak chhuah a ni. He plasma hi Hepatitis leh HIV ang chi natna khirh tak tak a awm leh awm loh lakkhawm leh test khauh tak a ni . Tichuan a fai a, a tithianghlim a, enkawlna atan hman a ni. Chuvangin a himna tur ngaihtuah tur a awm lo.
I enkawl ni chuan trained nurse chuan i kut chhunga vein pakhatah cannula te tak te a dah ang a, chuta tang chuan damdawi chu saline bag ang maiin i taksaah a lut ang. Hetiang hian darkar 2 leh darkar 4 inkar a awh thei tlangpui .
A tam zawkah chuan he enkawlna hi damdawi inah emaw, clinic-ah emaw, infusion center-ah emaw pek a ni. Mahse, a then phei chuan damdawi lam thiam trained tak chu i inah lo kal a, he enkawlna hi a pe thei che a ni.
He enkawlna hi eng chen nge i dawn a ngai tih hi thil tam takah a innghat a, chutah chuan i damdawi lam dinhmun leh i taksain a chhân lêt dân te pawh a tel a ni. Mi tam zawk chu kar 3-4 danah he enkawlna hi pek an ni tlangpui.
IVIg enkawlna hian side effect a nei em?
Mi tam zawk chuan he enkawlna hi an tuar tha hle. Mahse, damdawi dang ang bawkin side effect engemaw zat a nei thei a ni. A tam zawkah chuan hengte hi thil tenau tak a ni a, enkawl hnu lawkah a thleng thei bawk.
| IVIg enkawlna avanga side effects awm thei | |
|---|---|
| Side effect awm fo (non-serious) te | |
| Lu na | Chau tih hriatna, taksa ruh na |
| Khua a lum deuh, khawsik a awm | Vun a hring, a sen, a hring chhuak |
| Upper abdominal na a awm | Vung |
| Side effect na tak tak, doctor hnena report nghal tur (hengte hi a tlem hle) . | |
| Lu na nasa tak, kawr na tak | Thâwk harsa, rilru thawm, thawk hah |
| Thil danglam tak, hliam emaw thisen chhuak emaw | Hmai na, mit vel, khuh leh phlegm te |
| Pawimawh: Allergy symptoms (e.g., hives, chest tightness, wheezing) i neih chuan Emergency Department (ETU) hnai ber pan nghal rawh. | |
Thil dang pakhat chu, enkawl hnu ni hmasa berah chuan i dam tha hle mai thei. Chu chu i taksa antibody level sang ber a nih vang a ni. Mahse, enkawlna lo awm tur a hnaih deuh deuh chuan, chu antibody te chu i taksaah a luh hnu chuan, tlem chuan i chau a, i chak lo deuh mai thei. Hei hi thil pangngai a ni.
Engtin nge enkawl turin i inbuatsaih thin?
I enkawl ni-ah inbuatsaih leh hahdam taka awm a pawimawh hle. I tanpui theihna tur tips thenkhat chu hetiang hi a ni:
- Tui tam tak in rawh: I enkawl hma ni khatah, enkawl lai leh enkawl zawh ni khatah tui leh tui tam tak in thin ang che. Hei hian lu na ang chi side effects a thlen theihna chu nasa takin a tihziaawm dawn a ni.
- I damdawi chungchang zawt rawh: Natna dang atana damdawi i ei a nih chuan i doctor emaw nurse emaw hnenah i enkawl ni-ah chu damdawi chu ei tur leh ei loh tur zawt rawh.
- I intihhlimna tur thil rawn keng rawh: Hmun khatah darkar engemaw zat i awm dawn avangin, i phone-a lehkhabu, magazine, a nih loh leh movie ang chi intihhlimna tur thil rawn ken chuan i buai reng thei a ni.
- Thawmhnaw nuam tak ha rawh: Thawmhnaw nuam leh cannula dah awlsam tur ha rawh. Treatment centre-ah AC a awm avangin i vawt mai thei. Chuvangin inkhuh tur thil emaw, sweater emaw keng tel a tha.
- Thil tawn tawhte sawi rawh: Tun hmaa IVIg enkawlna avanga side effects i neih tawh chuan nurse hnenah enkawlna i tan hmain hrilh la, chutiang chuan an lo thlir reng thei ang.
Take-Home Thuchah a ni
- IVIg hi mi hrisel thisen atanga lak chhuah antibody hmanga taksa hriselna chak lo nei tan thisen kal tlanga pek thin a ni.
- Hei hian i taksa chu natna hrik do turin chakna a pe belh leh a ni.
- He enkawlna hi autoimmune natna leh thluak lam harsatna hrang hrang, Lupus, ITP, leh Myasthenia Gravis te tan hman a ni.
- Enkawlna hi darkar tlemte a ni a, side effect tenau te pawh a awm thei a, mahse a nasat erawh a awm lo. I doctor nen harsatna i neih chuan sawipui rawh.
- Enkawl hmaa inbuatsaih tha (a bik takin tui tam tak in) chuan side effects a tlem thei hle.
- He enkawlna hi i tan a tha em tih leh a thatna leh that lohna te chu i doctor nen zalen takin sawiho rawh.
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