Thisen i tlem em? Megaloblastic Anemia chungchang hi han sawi ila!

Nang pawhin i chau reng em? Nilengin i muhil a, i taksa pawhin engmah ti thei lovin nunna nei lo niin i inhria em? A chang chuan i vun a rawn sen a, thawk a harsa deuh thin em? Hengte hi thil pangngai anga hnawl mai mai suh. Chûngte chu i thisenah harsatna i neih chhinchhiahna a ni thei. Vawiin hian Megaloblastic Anemia , hetiang symptoms thlentu, a bik takin vitamin B12 leh vitamin B9 (folate tia hriat bawk) i tlakchham hunah kan sawi dawn a ni.

Megaloblastic Anemia tih hi eng nge ni?

A awlsam zawngin sawi ila, megaloblastic anemia hi thisen chhunga thisen sen (red blood cells) tichhe thei anemia chi khat a ni. Hemi a thil thleng chu kan ruhro atanga thisen sen lo chhuak chu a tlangpui aia lian a lo ni ta a ni . Chuvang chuan ‘macrocytic anemia’ an ti bawk a, chu chu thisen cell lian tak tak tlakchhamna tihna a ni.

Phên dangin sawi ila, hei hi vitamin tlakchhamna thisen tlakchhamna a ni. Hetiang dinhmun hi taksain ei tur tha pahnih vitamin B12 leh vitamin B9 ( folate ) a neih tlem chuan a thleng thin . Mahse lungngai suh, doctor ten he natna hi vitamin B12 leh B9 supplement pein an enkawl thei a ni.

Engtin nge megaloblastic anemia hian kan taksa a nghawng?

Tunah chuan en teh, kan taksa hian thisen zam hrisel engemaw zat a mamawh a ni. A chhan chu heng red cells te hi lung atanga taksa pum chhunga tissue thlenga oxygen phurtu an ni a, carbon dioxide an phur let leh bawk. Thisen cell dang zawng zawng ang bawkin thisen sen (red blood cells) hi kan ruhro (bone marrow)-a stem cell angin a intan a.

Vitamin B12 leh Vitamin B9 te hi thisen sen (red blood cells) siam that nan a pawimawh hle. An tel lo chuan kan taksa hian cell chi danglam tak, megaloblasts , a siam chhuak thin.

Ngaihtuah teh, heng megaloblast, cell hrisel ang maia inthen darh leh pung zel te hian cell thar an siam lo. Chumi awmzia chu ruhro (bone marrow)-a thisen sen (red blood cells) a tlahniam tihna a ni. A chhan dang chu heng cell pangngai lo tak takte hi an lian hle a ni. A lian em em a, a nihna takah chuan a chang chuan ruhro atang pawhin an chhuak thei lo va, thisenah pawh an lut thei lo. An tih pawhin heng cell pangngai lote hi red cell hrisel aiin an thi rang zawk a ni. Heng zawng zawng hi a inzawm khawm chuan taksaa thisen sen (red blood cells) a tlahniam a, thisen tlakchhamna (anemia) a thlen a, chu chu thisen tlakchhamna a ni.

Hei hi natna khirh tak a ni em?

Megaloblastic anemia thlentu pakhat chu vitamin B12 tlakchham vang a ni. Enkawl loh chuan vitamin B12 tlakchhamna hian thluak lam harsatna a thlen thei a ni . Entirnan, hriatrengna hloh, balance hloh, leh ke ruh chhunga tingling emaw prickling sensation, ‘paresthesia’ tia hriat. Chuvangin hei hi ngaihthah tur a ni lo.

He natna hi engtiang chiahin nge a hluar?

Megaloblastic anemia hi natna hmuh tur awm lo tak a ni lo a, mahse doctor-te chuan mi engzat nge vei tih chiang taka sawi theihna tur data an nei tlem hle.

Eng thilin nge megaloblastic anemia hi a thlen?

A hmaa kan sawi tawh ang khan a chhan ber chu kan ruhro hian vitamin B12 emaw vitamin B9 emaw a neih tlem vang a ni a, chu chuan taksa pum puia oxygen phur thei thisen sen hrisel tak a siam thei a ni.

Vitamin B12 tlakchhamna chhante chu engte nge ni?

Mi thenkhat chuan vitamin B12 tlakchhamna an nei a, a chhan chu vitamin B12 tamna ei tur, sa, sangha, artui leh bawnghnute te an ei tlem vang a ni. Mi dangte chuan vitamin B12 hi ei kawngah harsatna an nei a, chu chu damdawi lam thil engemaw vang emaw, damdawi lam enkawlna avang emaw pawh a ni thei. Chutiang dinhmunte chu:

• Pernicious anemia: Hei hi autoimmune disorder a ni a, taksain vitamin B12 a ei theih loh phah a ni.
• Gastrectomy: Hei hi surgery a ni a, pum chhung hmun thenkhat lakchhuah a ni. Hei hian vitamin B12 lakluhna a nghawng thei a ni.
• Zollinger-Ellison syndrome: Hei hi natna awm lo tak a ni a, taksain vitamin B12 a hip theih loh phah bawk.
• Blind loop syndrome: Hei hi kan ei tur ei tur chu intestine kaltlangin a kal tha lo va, hmun khatah a tang a, chutah chuan bacteria te an lo thang lian a, vitamin B12 an hmang zo vek a ni.
• Fish tapeworm infestation: He tapeworm infection hi sangha tui lo, hri kai ei avanga kai theih a ni. Heng tapeworms te hi vitamin B12 hip in an nung a ni.
• Pancreatic insufficiency: Hetiang dinhmunah hian i pancreas hian chaw ei tur digestive enzymes a siam tling thei lo. Hei hian i mamawh tur nutrient zawng zawng, vitamin B12 emaw B9 emaw i hmu tling lo mai thei tihna a ni.

Vitamin B9 (folate) tlakchhamna chhante chu engte nge ni?

Vitamin B9 (folate) tlakchhamna hi nitin kan ei leh inah thlai hring, thei, sa, leh legumes kan telh loh chuan emaw, folic acid hmanga tihchak ei tur emaw kan telh loh chuan a awm thei a ni. A chhan dang pawh a awm bawk:

• Digestive system natna: Crohn ’s disease emaw celiac disease ang chi natna i neih chuan i digestive system hian folic acid a hip tha lo mai thei.
• Zu in tam lutuk : Zu in tam lutuk te hian a chang chuan chaw aiah zu in an thlak thin. Chuvang chuan folate an hmu tlem hle.
• I thei leh thlai ei tam lutuk: Thei leh thlai i lum lutuk chuan a lumna chuan a pianphung anga awm folate chu a tichhia thei a ni.
• Hemolytic anemia: Hei hi thisen natna a ni a, i thisen sen (red blood cells) te chu a chhe vek a, i ruhro (bone marrow) chuan rang tawkin a siam leh thei lo.
• Damdawi thenkhat: Seizure damdawi thenkhat leh intestinal ulcer teUlcerative colitis damdawi pek hian folate hi a hip lut dik thei lo.
• Dialysis: Dialysis hmang mekte hian a chang chuan kal (kidney failure) vangin ei duhna a tlahniam thin. Hei hian ei leh in atanga vitamin B12 an hmuh zat a nghawng thei a ni. (Hetah hian B9 chungchang pawh i chhiar tur a ni, original article-ah B12 tih ni mah se, a context a zirin B9 pawh a ni thei bawk.)

Megaloblastic anemia natna lan chhuah dan chu engte nge ni?

Megaloblastic anemia natna lan chhuah dan hi thisen tlakchhamna chi dang nen a inang a:

• Chauhna: Nitin hna thawk thei lo khawpa chau anga inhriatna.
• Chak lohna: Mi taksa chu nunna nei lo, che thei lo leh engmah ti thei lo ang maia inhriatna.
• Pallor: I vun chu a tlangpui aiin a rawn sen deuh thin.
• Dyspnea: Thâwk harsa tih hriatna, thawk thûk taka lak harsat.
• Dizziness or fainting: Inher emaw, hriatna hloh emaw tihna.

A bik takin vitamin B12 tlakchhamna hian a chang chuan i nerve a tichhe thei a, i ke ruhte a ti na thei a, i taksa peng hrang hrang a ti na a, i hriatna a hloh a, i taksa ruh a tichak lo bawk.

Engtin nge doctor-te hian hei hi chiang taka an chhui chhuah?

Doctor-te chuan megaloblastic anemia hi taksa enfiahin, i natna lan chhuah dan zawhna zawtin an hmuchhuak thin. Thisen test pawh an order thei a, chungte chu:

• Full blood count (FBC): He test hian i thisen sen zat leh an hnathawh dan a enfiah thin.
• Peripheral blood smear (PBS): Hei hian i thisen cell te chu microscope hmanga en a huam a ni. Thisen test ṭhenkhat chu machine hmanga zirchiang ni mah se, hetiang hunah hian doctor chuan cell-te chu a en a, thutlukna a siam ṭhin.
• Reticulocyte count: Hei hian i ruhro chhunga thisen sen (reticulocyte) puitling lo awm zat a teh a ni. Hei hian doctor-te chu i ruhro hian thisen sen hrisel tak tak a siam chhuak tawk em tih hriat nan a pui a ni.

Hei hi engtin nge enkawl a nih?

Doctor ten megaloblastic anemia hi vitamin supplement pein an enkawl thin. Hei hi lo en ve teh:

• Vitamin B12 tlakchhamna enkawl dan: I doctor chuan vitamin B12 level a normal leh hma loh chuan kar tlemte chhung vitamin B12 injection a rawt thei ang. I vitamin B12 tlakchhamna hi i taksain B12 a lakluh theihna lama harsatna avanga lo awm a nih chuan i dam chhung zawng thla engemaw zat danah B12 injection i ei a ngai mai thei. Tin, pernicious anemia an tih natna avanga B12 tlakchhamna nei te chuan an dam chhung zawng B12 supplement an ei a ngai thei bawk.
• Vitamin B9 tlakchhamna enkawlna: I doctor chuan vitamin B9 tlakchhamna siamthat nan folic acid tablet a pe thei ang. Tin, i vitamin B12 level chu a normal limit chhungah a awm em tih an enfiah bawk ang. Hei hi a chhan chu a chang chuan vitamin B9 supplement hian megaloblastic anemia symptoms a tihziaawm thei a, a hnuaia vitamin B12 tlakchhamna (nerve tichhe thei) chu a khuh thei bawk.

Engtin nge he natna vei theihna hi kan tihziaawm theih ang?

A hlauhawmna tihtlem dan kawng hrang hrang a awm a:

• Vitamin B12 leh vitamin B9 awmna ei tur ngaih pawimawh hmasak ber tur ei leh in inthlau tak ei tum ang che .
• Zu in hi tihtlem rawh. Zu in fo hian i chaw ei dan a nghawng thei a, i taksain vitamin B12 a hip lut thei lo bawk.
• Heng vitamin te hi i ei theih lohna tur damdawi lam natna i neih chuan chu natna chu enkawl turin i doctor nen thawk ho rawh.

Vitamin B12 awmna ei tur:

• Ran chaw: Sa sen, sangha, vawk, artui, bawnghnute leh bawnghnute atanga siam thil dangte hian vitamin B12 a pai tam hle.
• Fortified foods: Hei hi ei tur chi hrang hrang, a pianphung anga awm lo vitamin leh nutrient thenkhat hmanga artificial taka tihchak a ni. Entirnan, chawhmeh chi hrang hrang, nutritional yeast, thlai hnute thenkhat, leh chhang thenkhat te hi a ni. Food package-a nutrition facts label hi enfiah a pawimawh a, chu chuan ei tur chu vitamin B12 a nei em tih enfiah a pawimawh hle.

Vitamin B9 (folate) tamna ei tur:

• Thlai: Thlai dum dum (spinach, kale ang chi), peas, bean, leh legumes te.
• Thei: Citrus thei (orange leh tangerine ang chi).
• Ran chaw: thin, tuifinriat thil, sa leh vawk.
• Egg leh bawnghnute atanga siam ei tur.
• Chaw chakna (fortified foods): Chhangphut, chhangphut, pasta, buhfai leh buhfai thenkhatah hian folic acid a awm a. Tin, ei tur package-a label en la, ei tur chu vitamin B9 (folic acid) a ni em tih enfiah bawk ang che.

Megaloblastic anemia ka neih chuan eng nge ka beisei theih ang?

Mi tam tak chuan vitamin supplement an ei hnuah megaloblastic anemia an dam leh thin. I doctor chuan i vitamin level chu a hun hunah a enfiah ang a, vitamin B12 leh vitamin B9 i ei tlem em tih a enfiah ang. Entirnan, enkawlna i tan atanga kar tlemte hnuah thisen test i nei thei a, chu chu supplement te hian i vitamin B12 leh/ emaw B9 level a tisang em tih i enfiah thei ang.

Engtin nge ka in enkawl ang?

Hetiang hian i in enkawl thei ang:

• Vitamin supplement hi doctor-in a tih ang chiah khan ei thin ang che.
• Vitamin B12 leh vitamin B9 i hmuh theih nan ei leh in hrisel siam rawh.
• I hriselna enkawl la , thisen tlakchhamna (anemia symptoms) i neih leh ang tih i hriat chuan doctor pan rawh.

Hriat reng tur chu, megaloblastic anemia i neih chuan vitamin B12 leh/ emaw vitamin B9 i dawng tlem tihna a ni. Heng vitamin te hian i taksain thisen sen hrisel tak tak siam turin a pui thin. Thisen sen hrisel tak takte hian i taksa pum puia oxygen phurh chhuahna hna pawimawh tak chu an thawk a ni. Vanneihthlak takin doctor te chuan he tlakchhamna hi an siam tha thei a, i vitamin B12 leh vitamin B9 level tihsan nan supplement an pe che a ni. Vitamin tamna diet i ei thei bawk a, i doctor hnenah vitamin B12 leh vitamin B9 i ei tlem em tih hriat theih dan tur i zawt thei bawk.

Thupui tawi (Take-Home Message) 1.1.

Okay, chuvangin vawiin a kan sawi tawh kha han recap leh ila. Megaloblastic anemia hi taksain vitamin B12 emaw vitamin B9 (folate) a tlakchham chuan ruhroah thisen sen lian tak tak, pangngai lo tak tak a siam chhuak thin a ni.

• A lan chhuah dan ber chu hah lutuk, chak lohna, vun dum, leh thawk harsatna te hi a ni. B12 tlakchhamna hian nervous system a nghawng thei bawk.
• A chhan chu ei leh in atanga heng vitamin te hi a tam tawk loh vang emaw, taksain a ei theih lohna damdawi lam thil vang emaw a ni.
• Thisen test hmanga hriat theih a ni a , a bik takin CBC leh Peripheral Blood Smear ang chi te hmanga hriat theih a ni.
• Enkawlnaah hian vitamin B12 leh folic acid supplement te a tel a, mi thenkhat chuan hun rei tak an ei a ngai mai thei.
• A ven leh enkawl dan tha ber chu vitamin B12 leh B9 tamna ei leh in inthlau tak ei te, zu tihtlem te, leh a hnuaia awmte dik taka enkawl te hi a ni.

Chuvangin, heng symptoms te hi i neih chuan a rang thei ang bera doctor thurawn lak hi a finthlak hle ang. A chhan chu a hmaa hriatchhuah a nih chuan enkawl a awlsam a, dam lehna a rang zawk.