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MELAS Syndrome hi eng nge ni? A awlsam zawngin i hrethiam ang u!
A awlsam zawngin sawi ila, MELAS Syndrome hi kan cell chhunga mitochondria an tih peng te tak te te hian hna an thawk tha lo a nih chuan a lo awm thin a ni. Kan cell-te tana chakna siamtu heng power plant te tak te ang hian han ngaihtuah teh. Heng power plant te hian hna an thawk tha lo a nih chuan taksa pumin a hre thin. MELAS tih thumal hi he natna thil pawimawh engemaw zat inzawmkhawm atanga siam a ni a:- Mitochondrial encephalomyopathy: Hei hian mitochondria nena inzawm thluak leh taksa peng hrang hrangte nghawng thei natna a kawk a ni .
- Lactic acidosis: Hei hi kan taksaah chemical lactic acid an tih a lo awm khawm hian a ni. A tlangpuiin lactic acid hi kan ei carbohydrates hmanga chakna siam chhuah hian byproduct angin a lo piang a, mahse he natnaah hian a tam lutuk a ni.
- Stroke -like episodes: Hei hi a tam ber a ni. Stroke ang chi symptoms an nei niin a lang , mahse a takah chuan stroke an ni lo. Chûngte chu a thleng nawn leh thei a ni.
Hetiang dinhmun hi engtiang chiahin nge a awm?
MELAS Syndrome hi a hluar vak lo. Mi 4,000 zinga pakhat velin he natna hi an vei nia chhut a ni. Tu pawh a nghawng thei a, mahse a bik tak chu he natna hi nu atanga rochun chauh a ni. Pa hnen atanga naute hnena pek chhuah a ni lo.
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Check Availability →MELAS Syndrome natna lan chhuah dante chu engte nge ni?
Kan sawi tawh ang khan mitochondria hi kan taksa cell zawng zawngah te hian a awm vek avangin MELAS Syndrome hian eng organ emaw tissue emaw a nghawng thei a ni. Chumi avang chuan mi hrang hrangah symptoms a inang lo thei hle. Mahse, mi tam tak tan chuan a natna lan chhuah dan hi a na lo hle a, neurologic symptoms a thlen thei lo.Diabetes Mellitus leh hriatna hloh a hmuh theih. Hei pawh hi he natna ngaihtuah tur hian a tlem hle.Thluak kaihhnawih (neurological) lama harsatna leh a lan chhuah dan
Hengte hi stroke ang chi episode vang a ni ber. Thil thleng thei thenkhat chu hetiang hi a ni:- Thiltih danah pawh inthlak danglamna a awm nghal .
- Rilru chu a buai ta , thil thleng chu a hrethiam thei lo.
- Luak chhuak emaw balance hloh emaw .
- Taksa peng pakhat, entirnan kut emaw ke emaw chu a paralyzed (paralysis) .
- Taksa sir khatah rilru hah emaw, tingling emaw ang maiin a awm.
- Lu na hi a lo thleng a, a kal zel a, a châng chuan mit emaw, thusawi emaw a inthlâk danglam thei bawk .
- Fit a lo thleng dawn ( seizures ) .
- Thusawi slurred , tawng harsa.
- Mit lama harsatna a awm – mit pahnih emaw, mit hmuhna hloh vek emaw.
- Taksa sir khatah chak lohna hriat.
Vawi khata heng symptoms pakhat emaw a aia tam emaw i tawn chuan ngaihthah suh. Damdawi lam thurawn lak nghal a tha ber.
Taksa peng dang nghawng thei symptoms
Thluak kaihhnawih symptoms bakah hian he natna hian taksa peng dang a nghawng thei bawk.- Short stature – Mi thenkhat chu a tlangpui aia tawi zawk an ni thei.
- A rilru a buai em em a .
- Pum natna .
- I feel very tired , engmah tih theihna chakna ka nei lo ang maiin.
- Muscle cramps , chu chu taksa ruhte a inthlak danglam ang maia hriatna a ni.
Engvangin nge MELAS Syndrome hi a lo awm? Eng nge a chhan?
Hei hi a chhan ber chu kan genes (genetic variations) inthlak danglamna thenkhat vang a ni. Kan cell zawng zawngte hnathawh tûra an mamawh thupêk chu kan DNA- ah a awm tih i hria a ni . He DNA an tih information store-ah hian inthlak danglamna, a nih loh leh mutation a awm chuan cell te hi an thawk tha thei lo. MELAS Syndrome-ah pawh hetiang bawk hian a thleng thin. A pawimawh ber chu, MELAS Syndrome i neih chuan chu genetic variation chu i nu hnen atangin i rochun a ni.Hei hi mitochondria-a DNA inthlak danglam vang a ni.Hemi atan hian tute nge hlauhawm ber?
He natna vei theihna tur ber chu chhungkaw history a ni . Chumi awmzia chu nu emaw, nu lam atanga chhungte emaw hian he natna hi an vei a nih chuan naupangte pawhin an vei theihna tur hlauhawmna engemaw chen a awm tihna a ni.MELAS Syndrome avanga harsatna awm thei te chu engte nge ni?
MELAS Syndrome hi symptom tlemte chauh lantir a, tihtawp mai mai a ni lo. It can lead to further complications , chu chu hriselna lama harsatna dang a thlen thei a ni.- Thinlung lama harsatna a thlen thei a , dementia pawh a thlen thei bawk .
- Zunthlum (Diabetes Mellitus) natna (Diabetes Mellitus) .
- Hearing problems , hriatna hloh vek pawh a ni thei.
- Muscle issues – muscle spasm, taksa ruh control hloh ang chi thil.
- Gait leh balance chungchang .
- Mit hmuhna hloh .
- Liver lama harsatna a awm .
Engtin nge doctor-te hian hei hi an hriat chian?
Heng symptoms te hi i neih chuan doctor chuan i symptoms te leh i chhungte zingah hian hetiang natna hi an nei tawh em tih te (medical history) a zawt hmasa ang che. Tichuan test hrang hrang an order ang.Diagnostic test hrang hrang: 1.1.
- Genetic tests: Hei hian genetic variation a awm leh awm loh chiang takin a hril a ni.
- Imaging tests: Entirnan , MRI (Magnetic Resonance Imaging) scan hmangin thluak dinhmun enfiah theih a ni. Hei hian stroke ang chi dinhmun avanga thluak chhiatna a enfiah thei bawk.
- Cerebrospinal fluid, zun leh thisen test: Hengte hian lactic acid level ang chi thil a check thei a ni.
- Muscle biopsy: A chang chuan a tul chuan taksa peng te tak te chu lak a ni a, microscope hmangin mitochondria-ah danglamna a awm em tih enfiah a ni.
MELAS Syndrome hi eng enkawlna nge ni?
Vanduaithlak takin tun dinhmunah MELAS Syndrome hi damdawi a la awm lo. Chumi awmzia chu damdawi awm reng a awm lo tihna a ni. Mahse, natna lan chhuah dan thunun thei leh nunphung tichangtlung thei enkawlna a awm . Doctor-te chuan heng symptoms te hian nghawng a neih chu tihziaawm an tum thin.Symptoms hriat theihna tur damdawi: 1.1.
I doctor chuan hetiang damdawi hi a rawn rawt thei ang:- Antiseizure damdawi: Mahse, seizure damdawi valproate hi heng damlote tan hian a tha lo a , chuvangin doctor-te chuan damdawi tha dang an pe leh ang.
- Coenzyme Q10 emaw L-carnitine: Hengte hi vitamin ang chi, mitochondria-a chakna siam chhuahna tipungtu leh natna kal chakna tikhawtlai thei nia rin a ni.
- L-arginine leh L-citrulline: Hengte hi amino acid an ni. Research atanga a lan dan chuan stroke ang chi episode awm tam lutuk tihtlem nan leh thluaka chhiatna an thlen thin pawh tihtlem nan an pui thei a ni.
- Insulin emaw Metformin: Zunthlum i vei chuan heng damdawi te hi a control theih nan pek theih a ni.
- Vaccine: MELAS Syndrome vei te chuan an naupan laia vaccine an lak thuai thuai tur a ni. Kum tin COVID-19 vaccine, flu vaccine, leh pneumonia vaccine lak a pawimawh bawk a, hri kai hian an dinhmun a tichhe zual thei a ni.
Damdawi hmang lo enkawlna: 1.1.
Damdawi bakah hian doctor chuan hetiang hi a rawt thei bawk:- Muscle tihchakna tur leh hnathawh thatna tur exercise routine.
- I hriatna lama harsatna i neih chuan cochlear implants ang chi hmanrua aṭangin ṭanpuina i dawng thei ang .
MELAS Syndrome ka neih chuan eng nge ka beisei ang?
Hei hi dam theih loh natna a nih avangin i dam chhung zawngin i dinhmun hi i enkawl a ngai dawn a ni . A awlsam lo hle a, mahse damdawi lam thurawn leh puihna mumal tak nen chuan tih theih a ni. He natna hian taksa peng emaw, taksa peng emaw eng pawh a nghawng thei avângin, healthcare provider team ṭanpuina i mamawh mai thei . Entir nan:- Neurologist te an ni
- Geneticist te chuan an ti a
- Cardiologist te an ni
- Physical therapists – taksa ruh leh ruhkawr hnathawh dan tur
- Occupational therapists – nitin hna awlsam zawka thawk thei tura puitu
- Speech therapist – thusawi harsatna nei tan
- Social worker-te – rilru lam leh khawtlang puihna atan
MELAS Syndrome nen hian eng chen nge i dam theih ang?
Hei hi mi tam takin an zawh thin a ni. "MELAS Syndrome vei hi eng chen nge a dam theih ang?", tih zawhna hi chhanna dik tak pek a harsa hle. Hei hi mi tin a inang lo em em vang a ni. Mi thenkhat chuan symptoms an nei tlem zawk a, thenkhat chuan an nei tam zawk. Enkawlna an dawn dan pawh a inang lo. Chhungkaw khat chhungah pawh natna lan chhuah dan leh a zual zel dan a inang lo thei hle. Amaherawhchu, thudik kan hriatthiam a ngai a ni. MELAS Syndrome hi natna thenkhatah chuan thihna thlen thei a ni. Chu chu nunna atana hlauhawm pawh a ni thei tihna a ni. Chuvang chuan he natna chungchang hi hriat chian a, a tha thei ang bera enkawl a pawimawh.Hei hi ven theih a ni em?
Vanduaithlak takin tunah hian MELAS Syndrome hi genetic condition a nih avangin ven theih dan tur a awm lo. Amaherawhchu, chhungkuaa mi tu emaw hian hetiang ang chi thlahtu natna a neih chuan chu chhungkuaa awmte tan chuan genetic counselor hmuin thurawn lak a pawimawh hle. Nakin lawka naupangte’n he natna hi an rochun theih dan tur leh a venna atana hmalak dan tur te an pe thei a ni.MELAS Syndrome vei angin engtin nge ka in enkawl ang?
MELAS Syndrome i neih chuan i in enkawl that a pawimawh hle.- I doctor thupek ang chiah kha zawm rawh. A hun takah clinic-ah kal la, damdawi pek dik tak ei rawh. Doctor chuan kum khatah vawi khat tal hmu turin a hrilh mai thei che.
- Kum tin test thenkhat tih a ngai dawn a ni . Entir nan:
- Lung lam dinhmun
- Thisen sugar level a awm
- Hriatthiamna
- Mit
- Zu leh zu in hi i bansan vek tur a ni a, heng thilte hian mitochondria a tichhe zual thei a ni.
- Kum tin flu shot, pneumonia shot leh doctor-in a rawt shot dangte chu a hun takah la rawh.
Doctor hnenah eng zawhna nge ka zawh ang?
Nangmah emaw i fa emaw hian mitochondrial disease an nei tih i hriat hian i rilru a buai tih hi thil pangngai tak a ni. Mitochondria chungchang pawh i la hre lo mai thei. Chuvangin MELAS Syndrome chungchang leh a neih awmzia chiang tak hriat a pawimawh hle. Heng zawng zawng hi i medical team te zawt rawh. Zawhna zawh hreh ngai suh. Zawhna i zawh theih ṭhenkhat chu hetiang hi a ni:- "Engte nge medical emergency hnaih tawh tih tilangtu symptom emaw chhinchhiahna emaw?"
- "Chutiang thil a lo thleng a nih chuan Doctor ka call nge emergency room-ah ka kal nghal ang?"
- "Hetiang dinhmun hi a pui thei tur special food plan a awm em?"
- "Eng damdawi nge ka tan i rawt? Eng side effect nge awm thei?"
- "Ka chhungte hian genetic counseling an neih a ngai em?"
- "Clinical trial-ah hian ka tel thei em?"
- "Kei leh ka chhungte kan tel theihna tur support group i rawn rawt thei ang em?"
Hemi atang hian kan hriat reng tur thil (Take-Home Message) .
Okay, chuvangin vawiin a kan sawiho pawimawh tak tak thenkhat hi han sawi nawn leh ila:- MELAS Syndrome hi genetic condition awm lo mahse na tak a ni a , kan cell-a energy siamtu cell mitochondria te hnathawh that loh vang a ni.
- Nervous system leh muscle te a nghawng ber a ni. A lan chhuah dan ber chu stroke ang chi natna leh taksaa lactic acid awmkhawm hi a ni.
- He natna hi nu atanga naute rochun theih a ni.
- Tunah hian damdawi kimchang awm lo mah se, natna lan chhuah dan enkawl dan tur leh nunphung tihchangtlunna tur enkawlna a awm.
- He natna vei kan neih hian specialist medical team te puihna te, chhungkaw tanpuina te, leh support group te hi a pawimawh hle.
- Zawhna zawh te, thu hriat tur zawng te, leh i mamawh tanpuina dawng te chu hreh ngai suh.
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