Depression damdawi (Monoamine Oxidase Inhibitors) chungchanga MAOI damdawi chungchanga i hriat tur

Nangmah emaw, i hnaih ber tu emaw hian lungngaihna i vei a nih chuan, a nih loh leh kan hriat vek angin lungngaihna i vei a nih chuan, chutiang damdawi an pek chungchang chu i hre tawh ngei ang. Vawiin hian chutiang damdawi chi khat, hlui deuh, mahse chak tak tak, Monoamine Oxidase Inhibitors , a tawi zawngin MAOIs tih chu kan sawi dawn a ni. Heng damdawite hi hman tlanglawn tawh lo mah se, doctor-te chuan special case thenkhatah chuan an la rawt reng a ni. Chuvangin eng nge an nih chiang taka hriat a pawimawh hle.

A awlsam zawngin, he MAOI hi eng nge ni?

MAOIs hi depression enkawlna atana hman thin damdawi chi khat a ni. Kan thluak chhungah hian chemical messenger bik an awm a, chu chuan kan mood control a, chu chu hlim leh hahdam taka min awmtir tihna a ni. Hengte hi neurotransmitter kan ti a. Serotonin, dopamine, leh norepinephrine tih ang chi hming i hre tawh mai thei. Chungte chu chu tirhkohte chu an ni.

Tunah chuan kan thluak ah hian enzyme pakhat Monoamine Oxidase kan nei ta a. Brain cleaner ang mai a ni a, he enzyme hian chu messenger te chu a paih chhuak thin. Depression nei mi pakhatah chuan thluaka heng messengers level hi a hniam thei hle.

Chuvangin MAOI damdawi hian a tih chu chu tifai enzyme hnathawh chu a titawp a ni. Tichuan chu thuchah hlim tak tak ( neurotransmitters ) te chu thluak chhungah rei zawk an awm a, an hna chu uluk takin an thawk ta a ni. Hei hian zawi zawiin depression symptoms a tihziaawmna chu a ni.

He category-a tel damdawi dang thenkhat chu:

• Isocarboxazid (Marplan) hmanga siam a ni.
• Phenelzine (Nardil) te hi a awm a.
• Selegiline (Emsam) tih a ni.
• Tranylcypromine (Parnate) tih a ni.

Antidepressant dang ang bawkin , he MAOI damdawi hian kar tlemte chhung a thawk thei a ni. Chutih lai chuan i doctor chuan i lungkhamna leh mut theih lohna thunun nân damdawi dang a pe thei a ni.

MAOIs hian eng side effect nge a neih tlangpui?

Damdawi dang ang bawkin hengte hian side effect engemaw zat a nei thei a ni. Mahse mi zawng zawng hian an hmu vek lo. Mi thenkhat chuan pakhat emaw pahnih emaw an dawng thei a, thenkhat chuan engmah an hmu lo thei bawk. Chuvangin hengte hi hmuh hlau suh. Hemi chungchang hi i doctor nen sawiho rawh.

MAOI hman huna hriat tur thil

Hei hi a pawimawh ber a ni. Thil thenkhat chu he damdawi nena inkawp hian side effect hlauhawm tak tak a thlen thei a ni. Chuvangin nang leh i chhungte tan he thil hi hriat chian a pawimawh hle.

1. Ei leh in lama harsatna (Food Interactions) .

MAOI i ei laiin ei tur thenkhat i ei chuan i thisen sang chu rang tak leh hlauhawm takin a sang thei a ni. Hei hi ‘Hypertensive Crisis’ an ti a. Hei hi medical emergency a ni. Chuvangin, he damdawi eitu tu emaw chuan a ti tur a niDiet bik i zawm a ngai a ni.

Chaw ei loh tur: 1.1.

• Cheese upa tawh: Cheddar, blue cheese, leh mozzarella ang chi cheese upa tawh, fermented.
• Sa hmin: salami, sausage, ham ang chi thil.
• Smoked or dried: Smoked fish, salmon, sangha hring, sardines.
• Zu thenkhat: red wine, beer thenkhat.
• Soy atanga siam chhuah: soy sauce, tofu.
• Thlai puitling banana leh avocado ang chi (a puitling kim chuan).

He list hi a kim lo. He damdawi hi i pek hunah chuan i doctor leh nutritionist te chuan ei loh tur ei tur list kimchang tak an pe ang che . A dik takin zawm rawh.

2. Damdawi dang nena harsatna (Drug Interactions) .

Chaw ei ang bawkin damdawi thenkhat hi MAOI nena ei hian a hlauhawm thei hle. Hei hian thisen sang a tisang nghal thei a ni.

A bik takin, antidepressant dang, natna tidamtu leh allergy damdawi te hian hei hi an inzawm thei a ni.

3. Serotonin Syndrome natna a ni

Hei hi thil awm lo mahse pawi tak, nunna atana hlauhawm thei a ni. Thluaka serotonin level hlauhawm taka a san chuan a thleng thin. He hlauhawmna hi MAOI hi serotonin level tisangtu damdawi dang (antidepressant dang, migraine damdawi, emaw, natna tidamtu thenkhat) nen i ei chuan a sang hle.

Serotonin syndrome natna lan chhuah dan:

• Hahdam lo leh lungkhamna nasa tak neia inhria
• Heart rate a sang, thisen sang a sang
• Diarrhea, luak chhuak, luak chhuak
• Thil awm lo hmuh emaw hriat emaw (Hallucinations) .
• Khawsik, thawk hah lutuk
• Ei duhna thunun theih lohna, taksa khur

Heng symptoms te hi i neih chuan damdawi in Emergency Treatment Unit (ETU) ah kal nghal rawh. A tul chuan Colombo National Hospital-a National Poisons Information Center- ah pawh thurawn dil theih a ni.

4. Mahni intihhlum tumna

FDA chuan antidepressant zawng zawng tan warning a tichhuak a ni. Chu chu, heng damdawi i ei tan tirh emaw, a dose thlak danglam emaw hian mahni intihhlum tumna a awm thei tihna a ni. Hetiang hlauhawmna hi thalai zingah a sang hle. Nangmah emaw, i hmangaih tu emaw pawhin chutiang ngaihtuahna a neih chuan, rei lo tein i doctor hnenah hrilh rawh.

Damdawi ei leh naupai tihtawp

Enkawlna tihtawp

MAOI damdawi ei khap nghal mai hi a hlauhawm hle. Chutianga tih chuan withdrawal symptoms a awm thei.

• Khawsik emaw, flu emaw chhinchhiahna, khawsik, taksa na, leh thawk hah te
• Mu thei lo
• Restlessness a awm
• Rilru tibuai
• Psychosis (Psychosis) a ni

Chuvangin damdawi ei khap a ngai nia i hriat chuan i doctor nen inbia hmasa phawt ang che. Zawi zawiin a ei tur tihtlem dan tur leh i hriselna tichhe lovin damdawi tihtawp dan tur a hrilh thei ang che.

Naupai lai hian

Naupai lai hian MAOIs hi a him leh him loh chungchang hi hriat tur a tlem hle. He damdawi i ei lai hian nau i pai a nih chuan, emaw, naupai i tum a nih chuan doctor hnenah hrilh nghal rawh. Doctor nen inbia hmasa lovin damdawi ei kha bansan ngai suh.