Damdawi i ei hian i beng a tichhe em? Ototoxicity chungchang hi han sawi ila!

Damdawi thenkhat, a bik takin natna khirh tak enkawlna atana hman thinte hian kan beng a tichhe thei a, chu chu kan hriatna leh balance tihna a ni tih i ngaihtuah ngai em? Hei hi thil awm thei tak a ni. Damdawi lamah chuan he dinhmun hi ototoxicity kan ti a. Lungngai suh, hei hi hriat chian a pawimawh. Chipchiar takin sawi ila.

Ototoxicity chu eng nge ni?

A awlsam zawngin, ototoxicity chu damdawi thenkhat side effect angin kan beng chhung lam tihchhiatna a ni. "Ototoxicity" tih thumal awmzia kan en chuan "oto" tih awmzia chu "beng" tihna a ni a, "toxicity" tih awmzia chu "poisoning" tihna a ni. Chu chu beng rimchhia ang chi dinhmun a ni. Kan beng chhungril hian sensory cells nalh tak tak a nei a. Heng cell te hian kan hriatna leh taksaah balance kan neih theih nan min pui thin. Damdawi thenkhat, entirnan, hri kai na tak damdawi leh cancer ang chi natna damdawi te hian heng sensory cell te hi a tichhe thei a ni. Chutah chuan he ototoxicity an tih hi a lo awm ta a ni.

Ototoxicity symptoms te chu engte nge ni?

Heng symptoms te hi mi zawng zawng tan a inang vek lo. A chang chuan damdawi ei tan hnuah symptoms a lang nghal thei bawk. Mi dangte tan chuan symptoms hi zawi zawiin leh zawi zawiin a lo lang thei bawk. Mak tak maiin damdawi thenkhat chuan damdawi an ei tan atanga kum nga chhungin heng natna lanchhuahna hi a thlen thei a ni. Vawi tam tak chu chhinchhiahna hmasa ber chu beng chhunga ri ri hriat hi a ni. Mi pakhatin midang a biak ang mai a ni thei a, "ringing" sound emaw "whooshing" sound emaw mai a ni thei bawk. Doctor te chuan hei hi tinnitus an ti a . Tinnitus hi hriatna hloh chhinchhiahna hmasa ber a ni thei bawk. A lan chhuah dan dangte chu:

• Hriatna hloh (beng pakhat emaw, beng pahnih emaw-ah).
• Kal laiin i balance hloh ang maia inhriatna, a bik takin stairs i chhoh hian.
• Zanah emaw, hmun thimah emaw kal harsa .
• Balance vawng reng turin ke inhlat taka kal a ngai.
• Oscillopsia chu thil che lote chu a inher ang maia hriatna a ni. Hei hi oscillopsia an ti a .
• Luak chhuak ang maia, i lu a inher ang maia, i kut a inher ang maia, emaw, chau deuha inhriatna.

Nitin hna i thawh laiin i luak chhuak nghal a, a nih loh leh i kal laiin i muhil tan a nih chuan eng ang nge a nuam lo ang tih han ngaihtuah teh? Hengte hi kan ngaihven tur chhinchhiahnate chu a ni.

Chu chuan naupang tê tête chu engtin nge a nghawng?

Hetiang dinhmun hi naupang tê tê, a bîk takin thusawi zir thei khawpa upa tawhteah a lo awm a nih chuan an zirlai leh mi dangte nêna inbiakpawhna daltu lian tak a ni thei a ni. Nu leh pa kan nih angin heng symptoms te hi kan ngaihven hle tur a ni:

• Sikul-ah emaw, thil dang zir lai emaw pawh ni se, ngaihtuahna seng reng harsa.
• Hun rei tak ngaihthlak a ngaih huna chau vat.
• Midang thusawi hriatthiam harsa, thusawi hreh, emaw, tawng lo tak tak emaw. A châng chuan hei hi naupang thusawi tihkhawtlai chhan pawh a ni thei bawk.

Naupangin thil zir a duh em em a, mahse a ngaihvenna a hloh thut a nih chuan, a nih loh leh an chau tih an sawi fo chuan, hei hi thil sual tih mai mai ai chuan tlem tal i ngaihtuah tur a ni.

Engvangin nge he ototoxicity hi a lo awm?

Doctor-te sawi dan chuan kan beng chhung (ototoxic drugs) tichhe thei damdawi chi 200 chuang a awm a. Heng damdawi thenkhat hi doctor hnen atanga prescription lak a ngai a ni. Mahse ṭhenkhat, entirnan, natna tidamtu ṭhenkhat chu damdawi dawrah damdawi ziakna tel lovin lei theih a ni.

A pawimawh ber chu beng tichhe thei nia sawi damdawi tam tak hi a takah chuan nunna chhanhimna damdawi pawimawh tak an ni. Entirnan, cancer damdawi te, a nih loh leh bacteria infection na tak damdawi te. Chutiang hunah chuan, nunna chhanhimna tûr damdawi ei hlawkna chuan beng chunga chhiatna tê tê a thlen theih aiin a tam zâwk daih a ni.

Tin, `(ototoxic)` damdawi thenkhat hian a tam lutuk a ei chuan a tichhe thei chauh a ni. Chutiang dose sang chu kan ei tlangpui lo. Beng tichhe thei damdawi chi hrang hrang chi hrang hrang a awm a:

Aminoglycoside antibiotics hmanga tihdam theih a ni

Hengte hi antibiotic chi khat, bacteria infection enkawlna atana pek thin a ni. Cancer damdawi te nen hian he damdawi chi (aminoglycosides) hi ototoxicity thlentu ber nia ngaih a ni. Entirna thenkhat chu hetiang hi a ni:

• `(Amikacin)` tih a ni
• `(Gentamicin)` tih a ni
• `(Kanamycin)` tih a ni
• `( Neomycin )` tih a ni
• `(Netilmicin)` tih a ni
• `(Streptomycin) hmanga siam a ni`
• `(Tobramycin)` tih a ni
• `(Vancomycin)` (Hei pawh hi a chang chuan he category-ah hian a tel ve bawk)

Chemotherapy damdawi hman tur

Cancer chi hrang hrang enkawlna atana hman tur damdawi. Chung zinga ṭhenkhat chu beng tan a chhiat phah thei a ni:

• `(Carboplatin) tih a ni
• `( Cisplatin )` tih a ni

Loop diuretics - "tui pills" tih a ni.

Heng damdawi te hi kal (kidney) in taksa atanga chi leh tui tam lutuk chu zun hmanga paih chhuah tir thei damdawi te an ni. Mi thenkhat chuan "tui pill" an ti bawk. Chung zinga ṭhenkhat chu:

• `(Bumetanide)` tih a ni
• `(Ethacrynic acid)` tih a ni
• `( Furosemide )` (He damdawi hi mi tam takin an hriat chian em em a ni)
• `(Torsemide)` tih a ni

Damdawi dang leh chemical chi hrang hrang

A tlem hle nachungin, ototoxicity hi hetiang hian a awm thei bawk:

• Quinine chu: 1.1.Malaria enkawlna atana damdawi pek thin te.
• Salicylates : Hengte hi over-the-counter natna tidamtu an ni . Kan hriat vek Aspirin hi salicylate chi khat a ni. Mahse, a dose sang leh rei tak ei a nih chuan harsatna a awm thei a ni.
• Environment-a chemicals : A châng chuan he dinhmun hi boruak chhunga mercury , tin, lead, leh carbon monoxide ang chi thilte vang a ni thei.

Risk factors te chu engte nge ni?

Hetiang ototoxicity natna vei theihna hi mi zawng zawng tan a inang vek lo. I damdawi ei dan azirin i doctor chuan heng risk factors te hi a hrilhfiah ang che. Thil awm dan tlangpui thenkhat chu:

• Damdawi i ei tur chi: Damdawi thenkhat chuan a dang aiin hetiang hi an keng tel zawk a ni.
• Damdawi hman dan tur: Engzat nge ei tur.
• Eng chen nge damdawi ei tur.
• Beng tichhe thei damdawi engemaw zat ei dun tur nge ei dun loh. Chutiang a nih chuan a hlauhawmna chu a pung lehzual thei a ni.

Chu bâkah, scientist-te chuan mi ṭhenkhat gene (DNA) pawhin nghawng a nei thei tih an hmu chhuak bawk . A bik takin, mi thenkhat genetic makeup (or structure) hian aminoglycoside antibiotics thenkhat ei hian ototoxicity an neih theihna a tipung thei a ni.

Ototoxicity avanga harsatna awm thei

Heng ``ototoxic`` damdawi hmanga beng chhung lam chhiatna hi ``ireversible`` a ni fo thin . Chumi awmzia chu hun rei tak chhunga hriatna leh balance lama harsatna a awm thei tihna a ni. A bîk takin naupang tê têteah chuan heng hriatna lama harsatnate hian an thusawi thiamna te, ṭawng zir theihna te, mi dangte nêna inbiakpawhna atana an mamawh thiamna te pawh a tikhawlo thei a ni. Ngaihtuah teh, naupangin thu a hriat thiam loh chuan engtin nge chu thute chu thusawi nan hman a zir ang? Mahse, chhiatna chu tihdanglam theih loh pawh ni se, doctor-te chuan i dinhmun chu an enfiah thei a, symptoms a lo awm chuan an enkawl thei a, a tul angin puihna an pe thei bawk.

Engtin nge he dinhmun hi kan hriat theih ang?

Heng symptoms te hi i neih chuan beng, hnar leh kawr lam specialist (otolaryngologist emaw ENT specialist) emaw, audiologist emaw i pan a ngai mai thei. I beng chhung lam enfiah turin test hrang hrang an ti ang a, i symptoms a zirin. A pawimawh ber chu i doctor hian ototoxic nia rinhlelh damdawi a pek hmain i hriatna leh balance a test hmasa thei ang.Tin, damdawi i ei lai hian heng test te hi a hun hunah i ti thei bawk. Chutiang chuan damdawi side effect anga inthlak danglamna a awm chuan rang takin i hre thei ang.

Eng test nge tih thin?

I beng chhungril hnathawh dan hriat duh chuan i doctor chuan hetiang test hi a ti thei ang:

• Audiogram: Hei hian aw hrang hrang, i.e. aw nem tak, aw ri nasa tak, aw sang leh hniam (pitch) i hriat that dan leh thumal i hriatthiam dan a test thin.
• Auditory Brainstem Response (ABR) test: Hei hian i auditory nerve-in aw a chhan dan leh chu chhanna chu thluaka a kal dan a test thin.
• Otoacoustic Emissions (OAEs) test: Beng chhung lam (cochlea-a sam cell)-a sam ang chi, a fim tak tak te hian aw chhanna atan vibrations (sound vibrations) zawi tak tak (sound vibrations) an tichhuak thin. He test hian heng vibrations te hi a teh a, cell te hian engtiang chiahin nge hna an thawh tih a enfiah thin.
• Vestibular test battery: Hei hi test pakhat chauh a ni lo va, balance lama harsatna awm leh awm loh enfiah nan test hrang hrang a ni. Entirnan, hei hian `(Videonystagmography - VNG)` (mit che vel en), `(Vestibular Evoked Myogenic Potentials - VEMPs)` (balance-a inrawlh nerve-te chhanna en), `(Rotary chair test)` (rotating chair-a thu chunga test), leh `(video Head Impulse Testing - vHIT)` tih ang chi test te pawh a huam thei.

Engtin nge ototoxicity hi enkawl a nih?

Vanduaithlak takin ototoxic damdawi tihtawp hian chhiatna lo thleng tawh chu a tidanglam thei lo. Mahse, damdawi tihtawp emaw, a dose tihtlem emaw (a theih chuan) hian chhiatna dang a thlen loh nan a pui thei a ni. Mahse, kan sawi tawh ang khan heng ototoxic damdawi te hian nunna a chhanhim fo thin. Chuvangin, tihtawp emaw, i enkawlna ruahmannaah inthlak danglamna lian tham siam emaw chu thil theih a ni lo. Chutiang hunah chuan i doctor chuan damdawi i dawn dan chu a enfiah ang a, i natna lan chhuah dan tur a enkawl ang che.

Symptoms enkawlna atana puitu hmanrua leh hmanraw

A chhiatna chu tihdanglam theih ni lo mah se, a natna lan chhuah dan nena nunpui theih dan tur a awm a:

• Hearing aids: Heng hmanrua te hian hriatna lama harsatna nei te, a bik takin hriatna lama harsatna nei te chu thil hriatna tha zawk leh inbiakpawhna awlsam zawka siam turin a pui thin.
• Cochlear implants: Hei hi electronic hmanrua a ni a, surgery hmanga beng chhungah dah a ni. Hriatna lama harsatna nasa tak nei, hriatna hmanrua pangngai hmanga chhanna tha lote tan an hmang fo thin.
• Vestibular siamthatna tur: 1.1.Hei hi training bik a ni. Vestibular therapist emaw physical therapist emaw nen thawk hovin i taksa chu beng chhung lam harsatna avanga balance lama harsatna awmte a insiamrem theih nan leh a hmachhawn theih nan exercise leh technique hrang hrang i zir ang. Hei hian symptoms, luak chhuak leh kal harsatna te a tihziaawm thei a ni.

Ototoxicity hi a veng thei ang em?

Hetiang dinhmun hi ven theih vek a ni ngai lo. A chang chuan, i nunna chhanhim nan ototoxic damdawi pek a ngai thin. Mahse, a natna lan chhuah dan i hriat hmasak chuan i doctor chuan rang takin a pui thei che a, chhiatna dang tihziaawmna turin hma a la thei bawk. I beng tichhe thei zawk damdawi i ei a nih chuan i doctor chuan a lo en reng ang che. Tin, eng symptom nge fimkhur tur tih leh i hriat chuan eng sign nge doctor pan tur tih a hrilh bawk ang che.

Hetiang dinhmun hi eng chen nge a daih ang?

Ototoxicity avanga beng chhung lam chhiatna chu a let leh thei lo . Chumi awmzia chu a chhiatna chu a awm reng tihna a ni. Mahse, i dinhmun azirin i doctor chuan i enkawlna ruahmanna (a theih chuan) chu a thlak danglam thei a, chu chuan chhiatna dang leh natna lan chhuah dan a zual zel loh nan a titawp thei a ni. Mahse, damdawi ei kha tihtawp theih a nih loh fo avangin i doctor chuan i natna lan chhuah dan tur enkawl dan tur ruahmanna rei tak a siam ang. I natna hmuhchhuah leh damdawi i pek dan azirin i doctor chuan ototoxic damdawi ei avanga hlauhawmna chungchang a sawipui ang che.

Engtin nge keimah leh ka fa ka enkawl ang?

• Damdawi eng pawh pek i nih chuan a hlauhawmna leh a nghawng dan tur chu i doctor nen sawiho rawh. Zawhna zawh hreh suh.
• Damdawi i ei tan hnua i hriatna, i balance emaw, i symptom dang emaw a danglamna thar i hmuh chuan, ototoxic nia i rinhlelh, a tenau pawh ni se, doctor pan nghal rawh.
• Naupang tê tê hnêna he damdawi hi pe tu nu leh pa emaw, enkawltu emaw i nih chuan i fate chunga thil danglam a awm chuan fimkhur hle ang che. Naupang tê têah chuan natna lan chhuah dan hriat a harsa thei hle. Hriatna emaw, inthlauhna lama harsatna emaw chhinchhiahna zawng bâkah, i fain ngaihtuahna a buaipui emaw, a chau reng emaw tih lantîrna eng pawh chu hre reng ang che. I fain lungngaihna a tawh mek hi hriatna lama harsatna vang pawh a ni thei. Thil ngaihtuah tur i neih chuan doctor pan la, thurawn la rawh.

Engtiang chiahin nge ototoxicity hi a intan?

Mi tin a inang lo. Mi thenkhat chuan damdawi an ei tan tirh hian side effect an nei nghal mai thei. Midang tan chuan heng symptoms te hi enkawl tan atanga kum nga hnuah chauh a lang lo thei bawk. Enkawlna leh damdawi thenkhat chuan nghawng a nei tlai hle. Hei vang hian i hriatna enfiah nan i doctor-in a rawt angin hriatna test neih fo a pawimawh hle.

Ototoxicity nena inzawm damdawi tam tak, antibiotics leh chemotherapy damdawi te hi nunna atana pawimawh tak a ni tih hre reng ang che. Beng chhung lam tichhe thei mahse, an ei a hlawkna, natna enkawlna emaw, nunna chhanhim emaw pawh nise, a hlauhawmna aiin a tam zawk daih.

I beng tana hlauhawm nia hriat damdawi i ei a nih chuan i beng chhungril lama vaukhânna chhinchhiahna lo awm thei chu i doctor nen sawiho rawh. Inthlâk danglamna i hriat hma chuan i doctor chuan a ṭanpui thuai thei che a, enkawlna ruahmanna fel tak a pe thei bawk che a ni.

Kan hriat reng tur pawimawh ber chu! (In lama hruai tur thuchah)

Okay, chuvangin thu pawimawh tak tak i hriat reng theih nan kan sawi tawhte khaikhawm ila:

• Ototoxicity chu damdawi thenkhat avanga beng chhung lam chhiatna a ni. Hei hian hriatna leh balance a nghawng thei a ni.
• Tinnitus (beng a ri), hriatna hloh, leh luak chhuak ang chi symptoms te chu fimkhur rawh.
• Nunna chhanhim thei damdawi ei hian hlauhawmna awm mah se, chu damdawi hlawkna chuan a hlauhawmna aiin a tam zawk fo thin. Mahse, a hlauhawmna hriat chian a pawimawh hle.
• Ototoxic damdawi pek i nih chuan i doctor nen sawiho la, test ruahman saah pawh tel ve rawh.
• Symptom thar i hmuh chuan, a tenau pawh nise, i doctor hnenah hrilh nghal rawh. Enkawlna rang tak hian natna a zual zel loh nan a pui thei a ni.

I hriselna enkawl hi i mawhphurhna a ni. He thu hian chutianga i tih theih nan a puih ngei kan beisei!