Cut te tak te atanga thisen chhuak tihtawp pawh i harsat lo em ni? Von Willebrand Disease chungchang hi han sawi ila!

A chang chuan cut te tak te, rei tak thisen chhuak lo tur i nei thin em? A nih loh leh hnar thisen chhuak fo i nei em? I chhungkuaa mi tu emaw pawhin chutiang harsatna chu an nei ve mai thei em? Chutiang a nih chuan hei hi i tan thil pawimawh tak a ni mai thei. Vawiin hian natna hmuh tur awm lo mahse a tlanglawn em em von Willebrand Disease tih kan sawi dawn a ni.

Von Willebrand Natna hi eng nge ni?

A awlsam zawngin sawi ila, von Willebrand Disease hi kan thisen a inzawm tha lo tihna a ni a, chu chu thisen chhuah tihtawp tura puitu process chu a chak lo tihna a ni. Hei hi hereditary a ni fo , chu chu nu leh pate chuan an fate hnenah natna hi an kai thei tihna a ni. Mahse, lungngai suh, hei hi enkawl dan tur a awm. Doctor-te chuan he thisen zam chhuahna atana pui thei damdawi an pe thei che a ni.

Von Willebrand Disease vei chu engtin nge a awm?

He natna vei hian a tlangpui aia thisen a chhuah tam thei. Ngaihtuah teh, ha tê tê tê emaw, ha lak chhuah emaw pawhin thisen chhuah a reh theih nân hun rei tak a daih thei a ni. Mi thenkhat chuan hnar thisen an nei fo thin. Hmeichhia tan chuan thlasik laiin thisen a chhuak nasa thei a, a nih loh leh nau neih hnuah thisen a chhuak nasa thei bawk.

Natna nasat ber berteah chuan a chhan hriat lohvin thisen a chhuak thei a, chu chu ruh emaw, taksa peng (soft tissue) emaw-ah a lut thei a ni. Hei hian a hring thei a, natna nasa tak a thlen thei bawk. Mi dangte tân chuan thisen tlakchhamna , thisen tlakchhamna pawh a thlen thei a ni.

Hetiang dinhmun hi engtiang chiahin nge a awm?

Hei hi a takah chuan khawvela thisen chhuahna natna awm tam ber a ni. Report thenkhat chuan American mipui 1% vel a nghawng niin an sawi. Khawvel pumah mi maktaduai khatah 23 leh 110 inkar velin he natna hi an vei thei niin an chhut. Mahse, heng zat hi a inang lo thei a, mi thenkhat chuan thisen chhuah harsatna nei mahse von Willebrand Disease . Mi thenkhat chuan kum tam tak chhung chu heng harsatna te hi an lo nei tawh mai thei a, mahse a tlai lutuk hma chuan hriatchhuah an ni lo.

Von Willebrand natna leh hemophilia hi thil inang an ni em?

Ni e, an pahnih hian thisen zam harsatna an nih laiin, von Willebrand Disease hi natna a ni a, a tlangpuiin a lan chhuahna a tlem zawk a, hemophilia aiin a na lo zawk bawk. Mahse, chu chu ngaihthah tur thil a ni tihna erawh a ni lo.

Von Willebrand Disease natna lan chhuah dan chu engte nge ni?

Natna vei tam tak chuan symptoms an nei lo thei lo , a nih loh leh symptoms na lo tak tak chauh an nei thei. Mahse, natna khirh zawk nei te chuan hetiang ang chi hi an nei thei a ni:

• Hnar thisen chhuak : Hei hi thisen chhuak pangngai mai a ni lo. Minute 10 aia tam thisen chhuak a ni thei a, kum khatah vawi nga aia tam hnar atanga thisen chhuak a ni thei bawk.
• Hliam atanga thisen chhuak: Hliam te tak te emaw, hliam dang emaw atanga minute 10 aia tam thisen chhuak.
• Hriselna: He natna vei te hian hliam an tuar awlsam hle. Heng hliamte hi vunah a flat mai ni lovin, a hring deuh a, a hring ang maiin a sang thei bawk. Heng hliamte hi cheng nga pawisa lem aiin a lian thei bawk.
• Iron tlakchhamnaIron-deficiency anemia : Anemia hi taksain thisen sen (red blood cells) a neih tlem vang a ni . Iron deficiency anemia hi kan taksain hemoglobin siamna tur iron a neih loh vang a ni . He thil, hemoglobin tia koh hian thisen sen (red blood cells) oxygen phur turin a pui a ni. Chuvangin, thisen kan hloh tam lutuk hian iron pawh kan hloh thei a, he natna hi kan nei thei bawk.
• Operation hnua thisen chhuak: He natna vei te hian thisen an chhuah nasa thei hle a, operation tenau, ha lak chhuah ang chi hnuah pawh thisen an chhuak nasa thei hle.
• Heavy menstruation : Hmeichhe thenkhat tan chuan an thlasik thisen chhuak a nasat em avangin darkar tin an pad emaw tampon emaw thlak a ngai a, emaw, an period ni sarih aia rei a daih chuan he natna lanchhuahna a ni thei.
• Nau neih hnua thisen chhuak nasa emaw, nau pai emaw.
• Thluak chhunga thisen : I ek chhunga thisen awm emaw, i ek chhuah hnua thisen awm emaw pawh nise, damdawi lam dinhmun dang chhinchhiahna a ni thei. Chuvangin doctor pan ngei ngei tur a ni .
• Zun chhunga thisen (hematuria): I zun laiin thisen i hmuh chuan, a bik takin thisen chu zun chhuah duhna nghal a nih chuan doctor hnenah hrilh nghal rawh

A pawimawh ber chu heng symptoms pakhat emaw a aia tam emaw i neih chuan ngaihthah suh la, doctor hnenah thurawn la rawh.

Eng thilin nge von Willebrand Natna hi a thlen?

Hei hi genetic disease a ni a . Chumi awmzia chu he natna hi kan genes inthlak danglam (mutation) avanga lo awm a ni tihna a ni. Heng genetic changes avang hian kan taksa hian von Willebrand factor tih protein chu a siam tha thei lo. Heng thilte hi kan thisen zam tura puitu protein an ni.

He von Willebrand factor hi plasma (kan thisen tui lam), platelet (thisen tichhe thei cell) leh thisen kalna kawng bang-ah te a awm a ni . A tlangpuiin thisen kalna kawng a chhiat chuan platelet te chu a chhiat hmunah a innghat a, thisen zam a siam a, thisen chhuah chu a titawp thin.Von Willebrand factor hi heng platelet te hi a inzawm tlat theih nan a pui a ni. Chuvangin, he factor hi i hloh tawk a nih chuan, emaw, i hloh vek chuan platelet te hi a inzawm tha thei lo. Tichuan thisen zam (blood clot) a lo awm theih nan hun a duh rei zawk.

Mi tam zawk chuan an nu leh pa pakhat hnen atanga mutated gene an rochun atanga natna hi an vei thin . Hei hi autosomal dominant inheritance an ti a . Mi dangte chuan nu leh pa pahnih aṭangin mutated gene hi an rochun thei bawk . Hei hi autosomal recessive inheritance an ti a, natna khirh ber a ni. He mutated gene kengtu hian a fate hnenah mutation hi a thlen theihna chance 50% a nei a ni.

Tin, a châng chuan von Willebrand natna hi damdawi lam thil dang, cancer , autoimmune disorders , thinlung natna, leh thisen kalna lam natna te avânga harsatna angin a lo awm thei bawk.

Engtin nge doctor-te hian von Willebrand Disease hi an hriat theih?

Doctor i hmuh hunah i symptoms te an zawt hmasa ang che. I chhungkuaah hian hetiang natna lan chhuah dan emaw, thisen chhuahna lama harsatna nei emaw an awm em tih an zawt thei bawk. Tichuan test thenkhat an ti thei a, chungte chu:

• Complete blood count (CBC): Hei hian i thisena thisen sen, thisen var chi hrang hrang leh platelet awm zat a teh a ni. Tin, i thisen sen (red blood cells)-a hemoglobin awm zat a teh bawk. Von Willebrand natna vei tam zawk chuan CBC pangngai an nei a. Amaherawhchu, thisen chhuak tam mite chuan hemoglobin an hniam a, thisen zam (red blood cell) an tlem thei bawk.
• Platelet aggregation tests: Hei hian i platelet te chu thisen zam siamna tura pui turin engtiang chiahin nge a inzawm tlat tih a test thin.
• Activated partial thromboplastin time test (APTT): Hei hian von Willebrand factor leh thisen zam tura puitu clotting factor dangte a test thin. Heng thilte level hi a tlangpui aia hniam a nih chuan thisen a inzawm rei zawk a ni.
• Prothrombin time (PT) test: Hei hian thisen zam thei thil dang a teh bawk.
• Fibrinogen test: 1.1.Fibrinogen hi thisen zam tura puitu protein dang a ni bawk.
• Von Willebrand factor antigen test: Hei hian i thisena von Willebrand factor protein awm zat a teh a ni.
• Ristocetin cofactor test: Hei hian von Willebrand factor hnathawh dan a teh a ni.
• Von Willebrand factor multimers test: Hei hian factor awm dan a en a.

I doctor hian thisen test vawi tam tak a neih a ngai mai thei a, a chhan chu hormone level ang chi thilte hian i thisena von Willebrand factor level a tidanglam thei a ni.

Von Willebrand natna hi chi hrang hrang a awm a. Doctor-te chuan eng type nge i neih chiah tih hriat tumin test tam zawk an ti ang. Heng chi hrang hrangte hi:

• Type 1: Hei hi a tam ber a ni. Damlo 60% leh 80% inkar chuan hetiang chi hi an nei a ni. Heng mite hian an thisenah von Willebrand factor a hniam hle. Symptoms an nei lo mai thei. An tih chuan an nêm hle.
• Type 2: Hetiang type-ah hian von Willebrand factor hian hna a thawk tha lo. Heng mite hian thisen chhuah nasat lo atanga thisen chhuak tlem an nei thei. Damlo 15% leh 30% inkar chuan hetiang chi hi an nei a ni.
• Type 3: Hei hi a na ber chi a ni. A tlem hle bawk. Damlo 5% leh 10% inkar a nghawng a ni. Heng mite hian an thisenah von Willebrand factor level hniam tak tak an nei a, a nih loh leh engmah an nei lo. Hei hian thisen chhuahna kawngah harsatna nasa tak a thlen thei a ni.

Von Willebrand Disease enkawlna tur engte nge ni?

Doctor ten he natna hi damdawi chi hrang hrang hmangin an enkawl a:

• (Desmopressin): Hei hi hormone a ni. Thisen a von Willebrand factor level a tisang a ni. Hei hi he natna enkawlna atana hman tlanglawn ber a ni.
• Von Willebrand factor infusions: Mi thenkhat chu thisen chhuah tihtawp nan he factor hi vein hmangin an pe thin. He enkawlna hi zai hmain pek theih a ni. Natna khirh tak nei thenkhat chuan an thisena factor level a awm reng theih nan he enkawlna hi an dawng fo a ngai mai thei.
• (Antifibrinolytics) tih hi a awm a.Heng damdawi te hian thisen zam (blood clots) lo awm tur venna hmangin hna an thawk a ni. I doctor chuan ha zai i nih emaw, thlasik thisen chhuak nasa tak i neih emaw chuan heng damdawi te hi a pe thei che a ni.
• Birth control pills: Hengte hian thlasik thisen chhuak nasa tak nei te tan a pui thin. Heng pill-a estrogen hormone hian thisenah von Willebrand factor level a tisang a ni.

He natna vei theihna hi ka ti tlem thei ang em?

Hei hi rochun atanga lo chhuak a ni fo thin . I nu leh pate hian he natna hi an vei a nih chuan an zinga pakhat emaw, an pahnih emaw hnen atangin i rochun thei a ni. Chuvangin a lo thang zel tur venna tur engmah kan tih theih a awm lo.

Hetiang dinhmun hi ka neih chuan eng nge ka beisei ang?

Doctor-te chuan von Willebrand natna hi an enkawl thei a, mahse an tidam kim thei lo . Mi tam zawk chuan type 1 emaw type 2 emaw an nei a, hliam an neih emaw, operation an mamawh emaw chauhvin enkawl an mamawh. Type 3 vei te hian thisen chhuahna control nan damdawi lam enkawl chhunzawm zel an mamawh mai thei.

von Willebrand Disease ka nei a. Engtin nge ka in enkawl ang?

Mi tam zawk chuan natna lan chhuah dan na lo leh na lo tak tak an neih avangin he natna nena nun hian thil tlemte ngaihtuah a ngai a ni:

• Hliam thlen thei thil tih loh tur: Infiamna nasa tak, entirnan football, rugby, leh hockey te atanga inthiarfihlim a tha ber.
• I doctor zawng zawng, i ha enkawltu pawh tiamin, he natna hi i nei tih hrilh rawh: chutah chuan operation hnua thisen chhuahna control dan tur an ruahman thei ang.
• Aspirin emaw, aspirin awmna damdawi emaw hmang suh.
• Von Willebrand natna i vei tih hria doctor-in a pek loh chuan nonsteroidal anti-inflammatory drugs (NSAIDs) , ibuprofen ang chi hi hmang suh.
• Vitamin E, sangha hriak, leh turmeric awmna nutritional supplement ei loh tur.
• Medical alert identification ngaihtuah rawh: Hetiang bracelet bun emaw, identification card ken emaw hian emergency-a damdawi lam enkawlna \ha tak i hmuh theih nan a pui thei che a ni.

Engtikah nge damdawi inah hmanhmawh taka ka kal ang?

I thisen chhuahna chu thunun theih lohvin damdawi inah kal nghal rawh . Hliam tenau a nih pawhin thisen chhuah a reh loh chuan damdawi lam thurawn la ngei ngei tur a ni.

Doctor hnenah eng zawhna nge ka zawh ang?

Von Willebrand natna i neih chuan he natna hian i nun a nghawng dan tur zawhna i nei thei. Doctor i zawh theih tur zawhna thenkhat chu hetiang hi a ni:

• Engvangin nge he natna hi ka neih?
• Ka fate hian he natna hi an rochun thei ang em?
• Hei hi a chhe zual dawn em ni?
• Hei hi eng enkawlna nge ni?
• Enkawlna hian eng side effect nge a neih?
• He natna avang hian thil thenkhat, zin emaw, infiamna emaw te hi ka ti thei dawn lo em ni?

A tawi zawngin, kan hriat reng tur thilte chu

Von Willebrand natna hi a hluar hle a, genetic blood clotting disorder a ni. Mi tam zawk chuan symptoms mild to moderate an nei thin. Hnar thisen chhuak fo an nei thei a, a nih loh leh hliam tenau te pawhin thisen chhuah tihtawp nan hun rei tak a la ngai thei bawk. Mi dangte chuan symptom na tak tak an nei bawk. Entirnan, an ruh chhungah thisen a chhuak thei a, ruh a na thei bawk.

Mi thenkhat chuan kum tam tak chhung chu he natna hi an nei tih an hre lo mai thei. I neih chuan thisen chhuah harsatna i neih chhan hriat chu a hahdamthlak mai thei. I fate pawhin he natna hi an nei ve mai ang tih pawh i hlau mai thei bawk. Doctor-te chuan chu natna chu tidam thei lo mah se, an enkawl thei a ni . I fate’n an rochun dawn em tih chungchanga i zawhnate pawh an chhang thei bawk. Von Willebrand natna vei tura i mamawh information te pawh an pe thei che a, chutiang chuan active, normal life i neih chu a titawp lo che a ni. Chuvangin, lungngai suh, i hriatthiam a, i enkawl thiam chuan i nunpui thei ang.