Kan in chhungah hian rat hi a tam hle a ni lawm ni? A chang chuan heng rannungte hi kan ngaihven vak lo. Mahse, heng thil nung te te hian natna khirh tak tak min thlen thei tih i hria em? Vawiin hian natna pakhat, rannungte’n rat ang maia an kai theih, kan nervous system pawh a nghawng thei chungchang kan sawi dawn a ni. Hei hi Lymphocytic Choriomeningitis, a tawi zawngin LCM kan ti a.
A awlsam zawngin, he LCM hi eng nge ni?
Hei hi virus avanga natna a ni. He virus (LCM virus) hi `(RNA virus)` chi khat a ni. A tlangpuiin rannung, mice, hamster, leh guinea pig te a kai hmasa ber thin. Kan in chhunga kan hmuh thin common mouse (`Mus musculus`) hi he hri kaitu ber a ni. Ngaihtuah teh, heng rannungte hi hri kai ni mahse, hrisel takin an lang fo thin. Ran thenkhat chuan an dam chhungin he hri hi an taksaah an keng tel a, natna lanchhuahna engmah an lantir lo. Chumi awmzia chu an dam chhungin he natna hi an darh thei tihna a ni.
Engtin nge he natna hi kan kai theih ang?
Hei hi a pawimawh ber a ni. He virus hi rannung
hri kai chuan zun, hmui, ek leh thil dang dangah a awm thei a ni. Tunah chuan han ngaihtuah teh, i in i tifai a, rulhut bawlhhlawh i paih a nih chuan, i kutah hliam te tak te emaw, hliam emaw i neih chuan, chu hmang chuan virus chu i taksaah a lut thei a ni. Tin, heng thil bawlhhlawh khawihtu kut hmanga i mit, hnar emaw, i hmui emaw i khawih chuan chuta tang chuan i kai thei bawk. Rannungin a seh che a nih chuan chu pawh chu hlauhawm tak a ni.
A tha ber chu he natna hi mi pakhat atanga mi dang kai a ni lo . So even if you get this infection , i chhungte emaw hnathawhna hmuna awmte emaw chuan i lakah hlauh tur an nei lo.
Mahse,
kan fimkhur bîk ngaina hmun pakhat a awm . Nu naupaiin he natna hi a vei chuan nausen pum chhunga naute hnenah nausen (placenta) kaltlangin a kai thei a ni. Hei hi naute tan chuan a hlauhawm hle. Chutiang a nih chuan naute hian harsatna a nei thei a, chungte chu:
- Congenital hydrocephalus: Hei hian naute lu chu a pangngai lo takin a ti lian thei a ni.
- Thluak thanlenna avanga rilru lama harsatna nei
- Mit tichhe (Chorioretinitis): Mit mit (retina) leh mit chhung lam (internal structures) te hi a chhe thei hle.
- Lu te tak tak (Microcephaly): Hetiang dinhmun hi nausen pum chhunga thluak a lo thang tha lo a nih chuan a lo awm thin.
- Mit lama harsatna nei
Tin, he virus hi organ transplant laiin a kai theih bawk.
Miin an neih hian eng symptoms nge a neih?
Mi tam tak (mipui 5% vel) he hri kai hian symptom an nei lo. I immune system a chak chuan i damlo tih pawh i hre lo mai thei. Mahse, taksa chak lohna nei, naupai ang chi tan chuan a pawi thei hle. Symptoms a lan tak tak chuan virus kai atanga ni 8 leh ni 13 inkarah a lang tlangpui. Natna hi
biphasic a ni . Chumi awmzia chu symptoms stage hmasa ber a lo lang a, ni engemaw zat a reh a, chutah chuan stage pahnihna chu a intan leh tihna a ni.
| Natna stage | Symptoms beisei tur a awm |
|---|
| Phase 1 ( kar khat vel a awh) . | Khawsik, taksa na, chaw ei chak lohna, lu na na tak, luak chhuak, leh luak chhuak. Mi thenkhat chuan ril na, khuh, rilru na, leh ruh na te an nei thei bawk. |
| Phase 2 (nervous system nghawng thei) 1.1. | Hei hi a dinhmun a nasat berna stage a ni. Meningitis emaw encephalitis emaw a thlen thei. • Meningitis: Khawsik sang, lu na, kawr khauh. • Encephalitis: Buaina, mutthilh, paralysis. A châng chuan ruhro (spinal cord) a nghawng (myelitis) a, chu chuan taksa ruh a tichak lo va, hriatna a hloh phah bawk. |
He virus hian thluak cell te chu direct-in a that lo. Mahse, kan immune system-in a chhân lêt chuan thluaka thisen var tam tak a pung khawm a ni. Chemical an siam chhuah hian thluak leh thluak khuh tu membrane (meninges) te chu a ti na a, a tichhe thei bawk. Thu lawmawm tak chu mi hrisel chu hei atang hian a dam chhuak vek thei tih hi a ni. Thi zat hi 1% aia tlem a ni. Mahse, natna dang ang bawkin, mi thenkhat chuan an dam hnuah hun rei tak chhung harsatna (e.g., bengchheng, ruh natna) an nei thei a ni.
Engtin nge hei hi i hmuh theih, Doctor?
Rat ang chi ran vulh i neih chuan, emaw, rat awmna hmuna i awm a, kan sawi tawh ang chi symptoms i neih chuan,
Doctor hmu ngei ang che. Heng symptoms te hi virus natna dang tam tak nen a inang avangin i doctor hian test eng emaw zat a neih a ngai mai thei a, chu chu a dik taka a hriat theih nan a ni.- Thisen test ( Full Blood Count ): Hei hian thisen var (leukopenia) a tlahniam a, thisen platelet a tlahniam (thrombocytopenia) a lantir thei bawk.
- Liver Function Test: Liver enzyme level a sang thei.
- Spinal Tap/CSF Study: He test hian cerebrospinal fluid-a thisen var a san leh glucose level a tlahniam leh awm loh a enfiah thin.
- Antibody Tests: Heng test te hian thisen leh cerebrospinal fluid-ah he virus laka antibody bik an zawng thin.
- PCR test: Hei hian virus genetic material (polymerase chain reaction - PCR) a awm leh awm loh dik takin a hriat theih a ni.
Enkawlnate chu engte nge ni?
Natna tenau i neih chuan i doctor chuan in lama enkawl dan tur a hrilh ang che. Hei hian khawsik, lu na, leh luak chhuak ang chi symptoms control nan damdawi pek che a huam a ni. Hei hi supportive treatment an ti a . Mahse, meningitis emaw encephalitis emaw ang chi natna khirh tak i neih chuan damdawi inah i awm a ngai dawn a ni . A châng chuan acute hydrocephalus veiah chuan pressure tihziaawmna turin emergency surgery neih a ngai thei bawk. Tunah hian he natna atana hman tur bik antiviral damdawi, mipui tana hman tur a awm lo. Laboratory test-ah damdawi ribavirin hi a thawk tha hle tih hmuhchhuah ni mahse, mihringah a thawk tha tih finfiahna a awm lo. A pawimawh ber chu: Engtin nge he thil hi i dam khawchhuah theih ang?
Damdawi aiin invenna hi a tha zawk fo. He natna hlauhawm tak laka inven nan hian thil awlsam tak tak i tih theih a awm.- I in chhunga mice lut kha titawp rawh: I in chhunga hawnna awm zawng zawng, bang leh crevice-a crack awm te, mice luh theihna hmun te chu seal up rawh.
- Faina: Rat awmna hmun leh an bawlhhlawh awmna hmun tihfai hian kutkawr vuah fo ang che . I kut i tihfai zawhah sahbawn hmangin uluk takin sil thin ang che.
- I ran vulhte enkawl rawh: Hamster emaw, rodent dang emaw i neih chuan an cage-ah vawn fai rawh. Cage i tihfai hian pawnah emaw, boruak luh theihna hmunah emaw tih tur a ni.
- Ramsa lakah inthiarfihlim rawh: Ramsa rulhut nena inhnaih loh tur.
- I ran vulh hmangaih dan: I ran vulh rat emaw hamster emaw chu i hmai hnaih taka fawh emaw, chelh emaw loh tur.
Mi hlauhawm bikte chuan rat hi an khawih loh vek tur a ni: hmeichhe naupai, naupai thuai tumte, leh cancer, HIV emaw damdawi dang ang chi natna avanga taksa hriselna chak lo nei te. In chhunga mi dangin i ran vulh te enkawl tir hi a tha ber.
Take-Home Thuchah a ni
- LCM hi rannung, rat ang chi ek leh zun atanga kai theih natna hrik a ni.
- Mi tam zawkin symptom an neih loh laiin, thenkhat chuan khawsik, taksa na an nei thei a, a nasat chuan thluak khawsik a awm thei bawk.
- Hei hi nu naupai tan chuan a hlauhawm hle a , nausen piang lai tan harsatna lian tak a thlen thei a ni.
- Rodent infestation laka invenna tha ber chu invenna a ni. In chhunga rulhut (rodents) control leh faina vawn that a pawimawh hle.
- Rat nena inhriat hnua symptoms a lo awm chuan doctor pan hmasa phawt tur a ni.
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