Mankhwala a Amvuttra a matenda osowa ofooketsa mitsempha (haATTR Polyneuropathy)

Kodi mumangomva dzanzi kapena kumva kupweteka m'manja ndi m'mapazi? Kapena muli ndi kufooka kwa minofu komanso kuyenda movutikira? Nthawi zina, zizindikirozi zimatha kuchitika chifukwa cha matenda osowa omwe sitinamvepo. Lero, tikambirana za vuto limodzi lotere komanso chithandizo chatsopano cha matendawa.

Kodi hATTR ndi chiyani? Kodi Amvuttra imagwira ntchito bwanji?

Mwachidule, hATTR (Hereditary Transthyretin-Mediated Amyloidosis) ndi matenda obadwa nawo. Ndi a m'gulu la matenda otchedwa amyloidosis. M'matendawa, mapuloteni ena m'thupi lathu amasintha mawonekedwe awo, amasonkhana m'njira zachilendo, ndipo amaikidwa m'ziwalo zosiyanasiyana.

Mu matenda a hATTR, puloteni yotchedwa Transthyretin (TTR) imayikidwa motere. TTR ndi puloteni yabwino yomwe imapangidwa m'chiwindi chathu ndipo imathandiza kunyamula mahomoni a chithokomiro ndi vitamini A m'thupi lonse. Komabe, munthu amene ali ndi matenda a hATTR amakhala ndi kusintha pang'ono mu jini ya TTR, ndiko kuti, kusintha kwa majini. Zotsatira zake, puloteni ya TTR yomwe imapangidwa imakhala yolakwika. Puloteni yolakwika iyi imasonkhana ndipo imayikidwa m'malo monga mitsempha, mtima, ndi dongosolo logaya chakudya monga malo otchedwa amyloid .

Pamene mitsempha iyi ikusonkhana mozungulira mitsempha, imawonongeka. Timatcha izi polyneuropathy . Apa ndi pamene zizindikiro zomwe tatchula kale, monga kutupa, dzanzi, kupweteka, ndi kuvutika kuyenda, zimachitika.

Mankhwala a Amvuttra amagwira ntchito pochepetsa kuchuluka kwa mapuloteni a TTR osazolowereka omwe amapangidwa ndi chiwindi. Izi zimachepetsa kuchuluka kwa amyloid m'thupi, zomwe zimathandiza kuchepetsa zizindikiro ndikuletsa kapena kuchedwetsa matendawa kuti asakule kwambiri.

Dokotala wanu adzakulangizaninso kusintha zakudya zanu ndi zochita zanu zolimbitsa thupi, pamodzi ndi kuchiza zizindikiro zanu. Mpaka posachedwapa, njira zokha zochiritsira matendawa zinali kuchepetsa zizindikiro ndipo, ngati pakufunika, kuyika chiwindi kapena mtima. Koma mankhwala amakono monga Amvuttra tsopano amakulolani kuwongolera matendawa pochepetsa puloteni ya TTR, yomwe ndi chifukwa chachikulu cha matendawa.

Kodi mumagwiritsa ntchito bwanji mankhwalawa?

Amvuttra ndi jakisoni yomwe imaperekedwa pansi pa khungu . Imaperekedwa ndi katswiri wazachipatala, monga dokotala kapena namwino wophunzitsidwa bwino. Nthawi zambiri imaperekedwa kanayi pachaka (miyezi itatu iliyonse) . Mutha kukonza zoti mulandire katemera ku ofesi ya dokotala wanu, kuchipatala, kapena ngakhale kunyumba.

Kodi mankhwala awa afufuzidwa bwanji?

Monga mankhwala atsopano aliwonse, Amvuttra yayesedwa m'mayesero azachipatala kuti adziwe momwe imagwirira ntchito komanso chitetezo chake. Mu kafukufukuyu, gulu la odwala omwe adalandira Amvuttra adayerekezeredwa ndi gulu la odwala omwe adalandira placebo , chithandizo chongopeka chomwe sichinali ndi chosakaniza chogwira ntchito. Umu ndi momwe tingadziwire ngati mankhwalawa amagwiradi ntchito.

Kafukufukuyu anaphatikizapo odwala omwe ali ndi matenda a hATTR komanso polyneuropathy yomwe inabwera chifukwa cha matendawa. Kufooka kwawo kwa mitsempha, mphamvu ya minofu, ndi luso lawo lochita zinthu za tsiku ndi tsiku zinayesedwa pogwiritsa ntchito njira zapadera zowerengera.

Malinga ndi zotsatira za kafukufukuyu, odwala omwe adalandira Amvuttra adasintha magwiridwe antchito a mitsempha ndi moyo wawo. Ngakhale kuti kuchuluka kwa mitsempha yawo kudachepa ndipo zizindikiro zidakwera, omwe adalandira placebo adawona kuwonjezeka kwa zizindikiro.

Kodi ndiyamba liti kumva zotsatira za mankhwala?

Iyi si njira yothetsera vutoli mwachangu. Pamene mankhwala akuyamba kugwira ntchito pang'onopang'ono m'thupi lanu, mungazindikire kuchepa kapena kusintha pang'ono kwa zizindikiro zanu mkati mwa miyezi ingapo . Cholinga cha nthawi yayitali cha chithandizochi ndikuchepetsa kupitirira kwa matendawa. Chifukwa chake, ndikofunikira kwambiri kuyang'anira zizindikiro zanu.

Uzani dokotala wanu kuti asamale ndi zinthu izi:

• Kutha kuyenda popanda thandizo
• Kusanza ndi kumva kuwawa m'miyendo
• Kusinkhasinkha kwa thupi
• Kulamulira kuthamanga kwa magazi mutaimirira

Ngakhale mutasintha mwadzidzidzi, musaphonye kulandira katemera wanu pa nthawi yake. Dokotala wanu angachitenso mayeso osiyanasiyana a magazi, ma scan, kapena mayeso akuthupi kuti aone momwe matenda anu akuyendera.

Zotsatirapo zake ndi momwe mungathanirane nazo?

Zotsatira zoyipa zomwe zimapezeka kwambiri ndi Amvuttra ndi izi:

• Ululu m'manja kapena m'miyendo
• Kupweteka kwa mafupa
• Kuvuta kupuma

Kuphatikiza apo, Amvuttra imatha kuchepetsa kuchuluka kwa vitamini A m'magazi mwanu . Chifukwa chake, dokotala wanu adzakuyezani magazi kuti awone kuchuluka kwa vitamini A m'magazi anu musanayambe komanso panthawi ya chithandizo. Ngati muwona kusintha kulikonse m'masomphenya anu, makamaka mavuto a masomphenya ausiku , dziwitsani dokotala wanu nthawi yomweyo.

Izi si zotsatirapo zokha zomwe zingachitike. Ngati muli ndi zizindikiro zatsopano zomwe zimakupangitsani kumva kuti simukusangalala, uzani dokotala wanu nthawi yomweyo.

Kodi pangakhale mavuto ndi mankhwala ena?

Amvuttra sakudziwika kuti imayambitsa kuyanjana kwakukulu ndi zakudya zina, zakumwa, kapena mankhwala. Komabe, ndi bwino kuuza dokotala wanu za mankhwala onse, mavitamini, mankhwala azitsamba, ndi zowonjezera zomwe mukumwa.