Kodi khansa yanu ya m'mawere ndi PR-Positive? (PR-Positive Breast Cancer) Tiyeni tikambirane izi mwachidule.

Mukapezeka ndi khansa ya m'mawere, dokotala wanu adzachita mayeso angapo kuti adziwe zambiri zokhudza maselo a khansa. Izi nthawi zambiri zimachitika potenga chidutswa cha minofu ya khansa kudzera mu opaleshoni kapena biopsy. Chimodzi mwa mayesowa ndikuwona ngati maselo a khansa ali ndi ' ma hormone receptors '. Ganizirani za ma receptor awa ngati 'ma loko' ang'onoang'ono pamwamba pa maselo. Pamene 'makiyi' otchedwa mahomoni alowa m'ma loko awa, maselo amalandira uthenga woti akule.

Progesterone ndi mahomoni omwe amapangidwa mwachibadwa m'matupi athu. Ndi ofunikira kwambiri pazinthu monga kutha msinkhu, kusamba, ndi mimba mwa akazi. Maselo ena a khansa ya m'mawere ali ndi ma receptors pamwamba pawo omwe amatha kumangirira ku mahomoni awa. Mtundu uwu wa khansa umatchedwa progesterone-receptor positive, kapena khansa ya m'mawere ya PR-positive (PR+). Chomwe chimachitika pankhaniyi ndichakuti mahomoni a progesterone amabwera ndi kumangirira ku maselo a khansa ndikuwathandiza kukula kwambiri. Chifukwa chake, mankhwala a izi amayesa kuletsa njira iyi ya mahomoni.

Homoni ina yomwe imagwira ntchito mofanana ndi estrogen. Ngati maselo a khansa ali ndi ma estrogen receptors, imatchedwa estrogen-receptor positive, kapena khansa ya ER-positive (ER+).

Ndani ali pachiwopsezo chachikulu cha matendawa?

Ngati maselo anu a khansa ali ndi PR-positive, ER-positive, kapena onse awiri, nthawi zambiri amatchedwa khansa ya m'mawere ya hormone-receptor (HR+). Mwamwayi, pafupifupi khansa 7 mwa 10 zomwe zapezeka ndi zamtunduwu. Ngakhale kuti khansa yamtunduwu imatha kufalikira pa msinkhu uliwonse, imapezeka kwambiri mwa akazi omwe adasiya kusamba.

Kawirikawiri, zinthu zomwezo zomwe zimakhudza khansa ya m'mawere zimakhudzanso khansa ya HR-positive. Tiyeni tiwone zomwe zili.

Kodi zizindikiro zake ndi ziti?

Nthawi zambiri, akazi ambiri samakhala ndi zizindikiro zilizonse akapezeka ndi khansa ya m'mawere, koma imapezeka mwangozi akamachitidwa mammogram nthawi zonse.

Zizindikiro za khansa ya m'mawere yokhala ndi HR-positive zimafanana ndi za mitundu ina ya khansa ya m'mawere . Nazi zina mwa zizindikiro zodziwika bwino.

Kodi chithandizo cha ma hormone chimagwiritsidwa ntchito bwanji?

Pokonza dongosolo lanu la chithandizo, dokotala wanu adzaganizira za momwe khansa yanu ilili ndi mahomoni. Chithandizo cha mahomoni ndicho chithandizo chachikulu komanso chofunikira kwambiri cha khansa yokhala ndi PR. Cholinga chake ndikuletsa maselo a khansa kugwiritsa ntchito mahomoni kuti akule.

Mwachidule, chithandizo cha mahomoni chimalepheretsa kupezeka kwa 'chakudya' (mahomoni) omwe khansa imafuna.

Izi zitha kuchitika m'njira ziwiri zazikulu:

• Kuchotsa mazira m'mazira obadwa kumene: Izi zimachepetsa kupanga mahomoni m'thupi.
• Mapiritsi kapena jakisoni wothandiza ndi mahomoni: Mankhwalawa amaletsa thupi kupanga mahomoni, kapena kuletsa ma receptors (kutseka) maselo a khansa, kuwaletsa kuti asagwirizane ndi mahomoni (makiyi).

Mtundu wa chithandizo cha mahomoni chomwe mumalandira chidzadaliranso ngati mwadutsa nthawi yosiya kusamba. Chithandizochi chingagwiritsidwe ntchito pa gawo lililonse la khansa. Kutengera ndi gawo la khansa, chithandizo cha mahomoni chimaperekedwa pamodzi ndi mankhwala ena, monga opaleshoni kapena chemotherapy.

Kodi mankhwala ena ndi ati?

Kuwonjezera pa chithandizo cha mahomoni, mungapatsidwe chimodzi kapena zingapo mwa zotsatirazi za khansa ya m'mawere yokhala ndi PR.

• Opaleshoni: Opaleshoni yochotsera maselo a khansa. Mwachitsanzo, kuchotsa chotupa chokha (Lumpectomy) kapena kuchotsa bere lonse (Mastectomy).
• Chemotherapy: Mankhwala amphamvu omwe amaperekedwa kuti awononge maselo a khansa.
• Chithandizo cha radiation : Chimagwiritsa ntchito mphamvu zambiri kuti chiwononge maselo otsala a khansa.
• Chithandizo Cholunjika: Mankhwala omwe amakhudza mapuloteni enaake omwe amathandiza maselo a khansa kukula. Izi zingathandizenso kupititsa patsogolo mphamvu ya mankhwala a mahomoni.

Kodi chiyembekezo cha matendawa ndi chiyani?

Nayi nkhani yabwino kwa inu. Khansa ya hormone-receptor-positive (HR+) imakonda kukula pang'onopang'ono kuposa khansa ya hormone-receptor-negative (HR-Negative). Komanso, muli ndi mwayi wopeza chithandizo chifukwa imatha kuletsa ntchito ya mahomoni ndikuletsa khansa kukula. Komabe, monga momwe zilili ndi khansa ina iliyonse, mankhwala amtsogolo amadalira momwe angapezekere msanga.

Koma pali chinthu choti mukumbukire. Ngakhale kuti chithandizo cha mahomoni chimatha kulamulira kukula ndi kufalikira kwa khansa, nthawi zina chingachitike patapita zaka zambiri kuchokera pamene chithandizo chaperekedwa. Ichi ndichifukwa chake madokotala nthawi zina amapereka chithandizo cha mahomoni kwa nthawi yayitali, nthawi zina kwa zaka 5 kapena 10.

Choncho, ndikofunikira kwambiri kulankhula momasuka komanso momveka bwino ndi dokotala wanu za momwe mahomoni amakhudzira khansa yanu komanso momwe ingakhudzire dongosolo lanu la chithandizo komanso njira yopitira patsogolo.