Kodi mwapezeka ndi matenda a Primary Biliary Cholangitis ( PBC ) , kapena monga momwe madokotala amanenera? Ngati ndi choncho, mwina mwayamba kale kulandira chithandizo. Koma kodi nthawi zina mumamva ngati mankhwala omwe mukumwa sakuthandiza monga momwe mukuganizira, ndipo matendawa ndi momwe alili? Ndizachibadwa kumva choncho, ndipo musadandaule nazo. Lero, tikambirana zomwe zimachitika ngati chithandizo chanu cha PBC sichikugwira ntchito, momwe mungachizindikire, ndi zomwe mungachite kenako.
Choyamba, kodi PBC ndi chiyani mwachidule?
Taganizirani za chiwindi chathu ngati chimodzi mwa mafakitale akuluakulu m'thupi lathu. Madzi ofunikira omwe amapangidwa mufakitale iyi amatchedwa 'bile'. Bile iyi imatithandiza kugaya chakudya chomwe timadya. Bile iyi imatuluka kuchokera m'chiwindi kudzera mu njira yofewa kwambiri ya machubu ang'onoang'ono ( njira za bile ).
Mu matenda otchedwa PBC, vuto la chitetezo chamthupi chathu limaukira njira zofewa za ndulu izi ndipo zimapangitsa kuti zituluke kuchokera mkati. Zili ngati chitoliro chamadzi chomwe chikutsekeka. Kenako, ndulu singathe kuyenda bwino ndipo imayamba kusonkhana mkati mwa chiwindi.
Poyamba, sipangakhale zizindikiro. Koma ndulu iyi ikachulukana pakapita nthawi, imawononga maselo a chiwindi ndi kuyambitsa zipsera. Vutoli likakula kwambiri, limatchedwa cirrhosis . Ngati silinalandire chithandizo choyenera, lingayambitsenso kulephera kwa chiwindi . Ndicho chifukwa chake ndikofunikira kwambiri kuyamba chithandizo mwachangu momwe mungathere.
Mankhwala oyamba omwe dokotala amapereka - UDCA
Mukapezeka ndi matenda a PBC, mankhwala oyamba omwe dokotala wanu nthawi zambiri amakuyambitsani ndi Ursodeoxycholic acid . Popeza n'zovuta kukumbukira dzina lalitali, tonsefe timalitcha UDCA mwachidule.
Zimene mankhwala a UDCA awa amachita zimathandiza kuti ndulu yomwe yasonkhana m'chiwindi ituluke mosavuta. Izi zimachepetsa kuwonongeka kwa chiwindi. Koma pali chinthu chimodzi chofunikira chomwe tonsefe tiyenera kumvetsetsa.
Mankhwala a UDCA awa sangachiritse matenda a PBC kwathunthu. Komabe, amatha kuletsa matendawa kuti asapitirire mofulumira, kulamulira kuwonongeka kwa chiwindi, ndikukuthandizani kukhala ndi moyo wabwinobwino.
Koma vuto ndilakuti, mankhwalawa sagwira ntchito mofanana kwa aliyense. Anthu ena sapeza zotsatira zomwe amayembekezera kuchokera kwa iwo.
Kodi mungadziwe bwanji ngati mankhwalawo sakugwira ntchito?
Kafukufuku wapeza kuti pafupifupi 40% ya anthu omwe amatenga UDCA, kapena anthu anayi mwa khumi, sapeza phindu lomwe amayembekezera kuchokera ku mankhwalawa. Anthu ochepa amakumana ndi zotsatirapo zoyipa monga kuvutika m'mimba ndi kutsegula m'mimba, zomwe zimapangitsa kuti zikhale zovuta kupitiriza kugwiritsa ntchito mankhwalawa.
Ngati chithandizo chanu sichikugwira ntchito bwino, mungapitirize kukhala ndi zizindikiro ngati izi kapena kuipiraipira.
| Chizindikiro | Momwe zimamvekera |
|---|---|
| Kumva kutopa kwambiri nthawi zonse | Kumva ngati wopanda moyo ngakhale mutagona bwino osachita chilichonse. |
| Kukanda khungu | Kuyabwa kosapiririka thupi lonse, makamaka usiku. |
| Khungu ndi maso zimakhala zachikasu | Zoyera za maso ndi khungu zimasanduka zachikasu, monga momwe zimakhalira ndi jaundice. |
| Maso ndi pakamwa pouma | Pakamwa pouma nthawi zonse komanso kumva kuuma, ngati mchenga m'maso. |
| Ululu m'mimba pamwamba kumanja | Ululu wosawoneka bwino wochokera ku chiwindi, kutanthauza, kumbali yakumanja ya mimba, pansi pa nthiti. |
| Kutupa kwa miyendo ndi mimba | Makamaka kutupa m'miyendo, m'mabondo, kenako m'mimba. |
Ndani amene ali ndi mwayi waukulu wosatenga UDCA?
Madokotala aona kuti anthu ena angakumane ndi zotsatira zochepa kuchokera ku UDCA. Izi zikuphatikizapo:
- Anthu omwe ali kale ndi matenda a chiwindi otchedwa cirrhosis.
- Anthu omwe ali ndi ma enzyme ambiri a chiwindi otchedwa gamma-glutamyl transferase ndi alkaline phosphatase m'magazi awo.
- Amuna (ngakhale kuti PBC ndi yofala kwambiri mwa akazi, imatha kukhala yoopsa kwambiri mwa amuna).
- Azimayi omwe adapezeka ndi matenda a PBC asanakwanitse zaka 45.
Kodi mungatsimikizire bwanji izi, dokotala?
Ngakhale zizindikiro zanu zitapitirira, dokotala sangaganize nthawi yomweyo kuti "mankhwalawo sakugwira ntchito." Pali njira yodziwira motsimikiza.
Mukayamba kulandira chithandizo, dokotala wanu adzakuyang'anirani nthawi zonse. Nthawi zambiri amalamula kuti muyesedwe magazi miyezi itatu kapena isanu ndi umodzi iliyonse. Koma nthawi zina zimatenga chaka chimodzi kuti mudziwe ngati mankhwalawa akukuthandizanidi.
Mayeso a magazi amenewa makamaka amayang'ana kuchuluka kwa ma enzyme a chiwindi chanu, makamaka Alkaline Phosphatase (ALP) ndi Bilirubin . Ngati kuchuluka kumeneku kukadali kwakukulu kuposa kwachizolowezi patatha miyezi ingapo mutatenga UDCA, kungakhale chizindikiro chakuti chithandizocho sichikugwira ntchito monga momwe amayembekezera.
Ngati zimenezo zitachitika, dokotala wanu angasankhe kuwonjezera mankhwala atsopano ku UDCA yanu kapena kukambirana nanu za njira ina yothandizira.
Ndiye ndiyenera kuchita chiyani?
Ichi ndi chinthu chofunikira kwambiri chomwe muyenera kudziwa kuchokera m'nkhaniyi.
Kulankhulana momasuka komanso moona mtima ndi dokotala wanu.
Ngati zizindikiro zanu sizikusintha kapena zikuoneka kuti zikuipiraipira, onetsetsani kuti mwauza dokotala wanu nthawi ina mukadzamuona. Musabise mfundo, kuganiza kuti, "Izi ziyenera kuti ndi zachilendo," kapena kuganiza kuti zidzasokoneza dokotalayo. Chilichonse chomwe mumaona kuti ndi chofunikira popanga zisankho za chithandizo.
Kumbukirani, kungoti mankhwala oyamba sanagwire ntchito sizikutanthauza kuti zonse zatha. Mankhwala apita patsogolo kwambiri. Pali njira zambiri komanso mankhwala atsopano oti akuthandizeni kuthana ndi vuto lanu. Chofunika kwambiri ndichakuti inu ndi dokotala wanu mugwire ntchito limodzi.
Uthenga Wopita Nawo Kunyumba
- PBC ndi matenda omwe amawononga machubu ang'onoang'ono omwe amanyamula ndulu kupita ku chiwindi. Ngati sachiritsidwa bwino, amatha kuwononga chiwindi kwambiri pakapita nthawi.
- UDCA ndiye chithandizo chachikulu komanso choyamba cha matenda a PBC, koma sichigwira ntchito mofanana kwa aliyense.
- Ngati zizindikiro monga kutopa pafupipafupi, kuyabwa kwa khungu, ndi chikasu cha maso zikupitirirabe ngakhale mutagwiritsa ntchito mankhwala, zingatanthauze kuti chithandizocho sichili choyenera kwa inu.
- Kulankhula ndi dokotala wanu za zizindikiro zanu ndi momwe mukumvera ndiye chinthu chabwino kwambiri chomwe mungachite kuti mukhale ndi thanzi labwino.
- Ngakhale chithandizo chimodzi sichikugwira ntchito, pali njira zina ndi mankhwala ochiritsira matenda anu. Choncho musachite mantha kapena kuchita mantha.
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