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Choyamba, tiyeni tiwone, n’chifukwa chiyani kutuluka magazi sikutha mu hemophilia?
Mwachidule, pali mapuloteni apadera omwe amathandiza magazi kuundana. Timatcha izi " zinthu zolimbitsa thupi ." Monga momwe matope amafunikira kuti agwirizanitse njerwa pomanga khoma, zinthu zolimbitsa thupi izi ndizofunikira kuti magazi asiye kutuluka. Munthu amene ali ndi hemophilia amakhala ndi vuto la magazi kuundana.- Anthu omwe ali ndi hemophilia A alibe chinthu chotchedwa Factor VIII.
- Anthu omwe ali ndi hemophilia B alibe chinthu chotchedwa Factor IX.
Ndiye kodi mankhwala atsopanowa otchedwa Qfitlia (fitusiran) ndi chiyani?
Iyi ndi mankhwala omwe amagwira ntchito mwanjira yachilendo kwambiri. Tinakambirana kale za mfundo yakuti magazi amafunika chinthu chotchedwa thrombin kuti aundane. M'matupi athu, pali puloteni ina yomwe imayang'anira kupanga kwa thrombin iyi, ndiko kuti, imaletsa kupanga kwa thrombin yambiri. Imatchedwa antithrombin .Taganizirani izi motere. Muli ndi chinthu chothandiza magazi kuundana (thrombin) m'thupi lanu chomwe chimathandiza magazi kuundana. Koma pali chinthu china (antithrombin) chomwe chimalamulira ndikuletsa kugwira ntchito. Mu hemophilia, kupanga kwa chinthu chothandiza (thrombin) kumakhala kochepa poyamba. Chifukwa chake chinthu choletsa (antithrombin) chikagwira ntchito bwino, magazi kuundana kumachepa kwambiri. Chomwe Qfitlia imachita ndikuchepetsa kuchuluka kwa antithrombin komwe kumalepheretsa. Kenako, kuchuluka kwa thrombin komwe thupi lanu limapanga mwachilengedwe kumaloledwa kugwira ntchito bwino popanda kulepheretsedwa. Izi zikutanthauza kuti imagwiritsa ntchito dongosolo la thupi kuti lilimbikitse magazi kuundana, m'malo mokupatsani chinthu chothandiza magazi kuundana chomwe mwataya. Uwu ndiye mankhwala oyamba ochepetsa magazi oletsa magazi kugwiritsidwa ntchito pochiza hemophilia.Tiyeni tifotokozenso kusiyana pakati pa njira ziwirizi zochiritsira.
Mutha kumvetsa kusiyana kumeneku mosavuta kuchokera pa tebulo ili m'munsimu.| Khalidwe | Chithandizo chachikhalidwe (Kusintha Zinthu) | Chithandizo cha Qfitlia (fitusiran) |
|---|---|---|
| Magwiridwe antchito | Chomwe chimapangitsa magazi kuundana chomwe chilibe mphamvu m'thupi chimaperekedwa kunja. | Amachepetsa antithrombin, yomwe imaletsa magazi kuundana, ndipo imalola thupi kugwiritsa ntchito thrombin yakeyake. |
| Momwe mungaperekere | Kawirikawiri kudzera m'mitsempha. | Pansi pa khungu (pansi pa khungu). |
| Kuchuluka kwa nthawi | Zingakhale zofunikira kangapo pa sabata. | Kamodzi pamwezi kapena miyezi iwiri iliyonse (ka 6-12 pachaka). |
| Kwa iwo omwe ali ndi zoletsa | Chithandizo cha zinthu zachilendo sichigwira ntchito, ndipo mankhwala ena apadera (omwe amaletsa kugwiritsa ntchito mankhwala ena) amafunika. | Mankhwalawa angagwiritsidwenso ntchito bwino kwa anthu omwe ali ndi zoletsa (ma antibodies motsutsana ndi zinthu zomwe zimayambitsa matendawa). |
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Check Availability →Kodi mankhwalawa ndi oyenera kwa ine ndipo ndimawagwiritsa ntchito bwanji?
Ngati muli ndi hemophilia A kapena B ndipo muli ndi zaka zoposa 12, dokotala wanu angaganizire ngati mankhwalawa ndi oyenera kwa inu. Chofunika kwambiri ndichakuti angagwiritsidwenso ntchito kwa anthu omwe apanga zoletsa (kukana) chithandizo cham'mbuyomu. Komabe, musanayambe chithandizochi, dokotala wanu adzachita mayeso angapo a magazi . 1. Mlingo wa antithrombin: Izi zimayesa kuchuluka kwa antithrombin m'magazi mwanu. Mlingo wa Qfitlia umatsimikiziridwa kutengera mtengo uwu. 2. Kugwira ntchito kwa chiwindi: Chiwindi chanu chimayang'aniridwa musanayambe komanso panthawi ya chithandizo. Mankhwalawa amaperekedwa ngati jakisoni pansi pa khungu (pansi pa khungu). Izi zikutanthauza kuti saperekedwa mumtsempha. Inu kapena wosamalira wodwalayo angakupatseni kunyumba mutaphunzira. Amaperekedwa pakhungu la m'mimba, ntchafu, kapena kumbuyo kwa mkono wapamwamba. Muyenera kupewa malo omwe ali ndi mikwingwirima kapena mabala. Ngati mukumwa kale mankhwala ena a hemophilia, mungafunike kusiya kapena kusintha mankhwalawo mutayamba Qfitlia. Dokotala wanu adzakufotokozerani momveka bwino. Musasiye kumwa mankhwala omwe muli nawo panopa kapena kusiya kumwa Qfitlia popanda upangiri wa dokotala wanu. Kuchita zimenezi kungakulitse chiopsezo chanu chotaya magazi.Kodi tiyeneranso kudziwa za zotsatira zake? Kodi tingapewe bwanji?
Monga mankhwala ena aliwonse, Qfitlia ikhoza kukhala ndi zotsatirapo zina. Ndikofunikira kudziwa za izi ndikuchitapo kanthu kuti mupewe.- Magazi Oundana: Popeza mankhwalawa amalimbikitsa magazi kuundana, nthawi zambiri magazi kuundana osafunikira amapangika m'mitsempha. Dokotala wanu adzasankha mlingo woyenera wa kuchuluka kwa antithrombin yanu kuti achepetse chiopsezochi.
- Ma enzyme a chiwindi okwera: Anthu ena akhoza kukhala ndi ma enzyme a chiwindi okwera. Ichi ndichifukwa chake madokotala nthawi zonse amawunika momwe chiwindi chilili ndi kuyezetsa magazi .
- Miyala ya m'mimba ndi Kutupa kwa ndulu: Ngati mwadzidzidzi mukumva zizindikiro monga kupweteka kwambiri m'mimba, nseru, ndi kusanza , dziwitsani dokotala wanu nthawi yomweyo.
- Matenda: Pali chiopsezo chochepa cha matenda pamalo obayira jakisoni. Chifukwa chake, ndikofunikira nthawi zonse kubaya jakisoni mwaukhondo komanso monga momwe dokotala wanu walangizira. Njira zabwino zodzitetezera, monga kusamba m'manja pafupipafupi, ndizofunikanso.
Uthenga Wopita Nawo Kunyumba
- Qfitlia (fitusiran) ndi mankhwala atsopano a hemophilia A ndi B omwe amagwira ntchito mosiyana.
- Izi zimagwira ntchito pochepetsa kuchuluka kwa antithrombin, komwe kumaletsa magazi kuundana, m'malo mopatsa thupi mphamvu yochepa youndana magazi kunja.
- Mankhwalawa ndi jakisoni pansi pa khungu, osati m'mitsempha, ndipo nthawi zambiri amaperekedwa kawirikawiri, monga kamodzi pamwezi kapena miyezi iwiri iliyonse.
- Dokotala wanu adzaona ngati chithandizochi chili choyenera kwa inu mutayesa magazi kangapo.
- Pofuna kupewa zotsatirapo zoyipa, ndikofunikira kuyezetsa magazi (makamaka antithrombin ndi ntchito ya chiwindi) nthawi ndi nthawi monga momwe dokotala wanu wanenera.
- Pewani kusiya chithandizo cha Qfitlia popanda upangiri wa dokotala pazifukwa zilizonse.
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