Kodi inunso simukuvutika kuletsa kutuluka magazi ngakhale mutadula pang'ono? Tiyeni tikambirane za matenda a von Willebrand!

Kodi nthawi zina mumadula pang'ono koma sikusiya kutuluka magazi kwa nthawi yayitali? Kapena mumatuluka magazi m'mphuno pafupipafupi? Mwina wina m'banja mwanu ali ndi mavuto ofanana? Ngati ndi choncho, ichi ndi chinthu chomwe chingakhale chofunikira kwa inu. Lero tikambirana za matenda osowa koma ofala kwambiri otchedwa von Willebrand Disease .

Kodi matenda a von Willebrand ndi chiyani?

Mwachidule, matenda a von Willebrand ndi matenda omwe magazi athu sauma bwino, zomwe zikutanthauza kuti njira yothandizira kuletsa kutuluka kwa magazi imafooka. Izi nthawi zambiri zimakhala zobadwa nazo , zomwe zikutanthauza kuti makolo amatha kupatsira matendawa kwa ana awo. Koma musadandaule, pali mankhwala a izi. Madokotala angakupatseni mankhwala omwe amathandiza ndi njira iyi youndana magazi.

Kodi chimachitika ndi chiyani kwa munthu amene ali ndi matenda a von Willebrand?

Munthu amene ali ndi matendawa amatha kutuluka magazi ambiri kuposa masiku onse. Tangoganizani, ngakhale kudula pang'ono kapena kuchotsa dzino kungatenge nthawi yayitali kuti magazi asiye kutuluka. Anthu ena amatuluka magazi pafupipafupi m'mphuno. Kwa akazi, amatha kutuluka magazi ambiri panthawi ya msambo, kapena amatha kutuluka magazi ambiri akabereka.

Pa milandu yoopsa kwambiri ya matendawa, kutuluka magazi nthawi zina kungachitike popanda chifukwa chomveka m'mafupa kapena minofu yofewa. Izi zingayambitse kutupa ndi kupweteka kwambiri. Kwa ena, zimatha kuyambitsa kuchepa kwa magazi m'thupi , komwe ndi kusowa kwa magazi .

Kodi vutoli ndi lofala bwanji?

Iyi ndi matenda ofala kwambiri okhudza magazi padziko lonse lapansi. Malipoti ena akusonyeza kuti imakhudza pafupifupi 1% ya anthu aku America. Padziko lonse lapansi, akuti anthu pakati pa 23 ndi 110 pa anthu miliyoni akhoza kukhala ndi vutoli. Komabe, ziwerengerozi zimatha kusiyana, chifukwa anthu ena akhoza kukhala ndi mavuto okhudza magazi koma osapezeka ndi matenda a von Willebrand . Anthu ena akhoza kukhala ndi mavutowa kwa zaka zambiri, koma sapezeka mpaka atachedwa.

Kodi matenda a von Willebrand ndi hemophilia ndi chinthu chimodzi?

Inde, ngakhale kuti zonsezi ndi vuto la magazi kuundana, matenda a von Willebrand ndi matenda omwe nthawi zambiri amakhala ndi zizindikiro zochepa ndipo sali oopsa kwambiri monga hemophilia . Koma sizikutanthauza kuti ndi chinthu chonyalanyazidwa.

Kodi zizindikiro za matenda a von Willebrand ndi ziti?

Anthu ambiri omwe ali ndi matendawa sangakhale ndi zizindikiro konse , kapena zizindikiro zochepa chabe. Komabe, omwe ali ndi matenda oopsa kwambiri akhoza kukhala ndi zizindikiro monga:

• Kutuluka magazi m'mphuno : Uku si kutuluka magazi wamba kokha. Kungatuluke magazi kwa mphindi zoposa 10, kapena kutuluka magazi m'mphuno nthawi zoposa zisanu pachaka.
• Kutuluka magazi kuchokera pachilonda: Kutuluka magazi kuchokera pachilonda chaching'ono kapena bala lina kwa mphindi zoposa 10.
• Mabala: Anthu omwe ali ndi matendawa amabala mosavuta. Mabala awa samangokhala pakhungu lokha, komanso amatha kutupa pang'ono ndikukwera ngati chotupa. Mabala awa amathanso kukhala akulu kuposa ndalama ya rupee zisanu.
• Kusowa kwa chitsuloKuchepa kwa magazi m'thupi chifukwa cha kusowa kwa ayoni: Kuchepa kwa magazi m'thupi ndi vuto lomwe thupi limakhala lopanda maselo ofiira okwanira. Kuchepa kwa magazi m'thupi chifukwa cha kusowa kwa ayoni kumachitika pamene thupi lathu lilibe ayoni okwanira kuti lipange hemoglobin . Chinthu ichi, chotchedwa hemoglobin, chimathandiza maselo ofiira kunyamula mpweya. Chifukwa chake, tikataya magazi ambiri, tikhozanso kutaya ayoni ndikukhala ndi vutoli.
• Kutuluka magazi pambuyo pa opaleshoni: Anthu omwe ali ndi matendawa amatha kutuluka magazi ambiri, ngakhale atachitidwa opaleshoni yaying'ono, monga kuchotsa dzino.
• Kusamba kwambiri: Kwa akazi ena, ngati kutuluka magazi m'mimba mwawo kuli kolemera kwambiri moti amafunika kusintha pedi kapena tampon ola lililonse, kapena ngati kusamba kwawo kumatenga masiku opitilira asanu ndi awiri, kungakhale chizindikiro cha vutoli.
• Kutuluka magazi ambiri pambuyo pobereka kapena kutaya mimba.
• Magazi mu ndowe: Kaya muli ndi magazi mu ndowe yanu kapena magazi mutamwa ndowe, izi zitha kukhala chizindikiro cha matenda ena. Chifukwa chake , muyenera kuwona dokotala .
• Magazi mu mkodzo (hematuria): Ngati muwona magazi mukamakodza, makamaka ngati magaziwo akubwera chifukwa cha chilakolako chofuna kukodza mwadzidzidzi, uzani dokotala nthawi yomweyo .

Chofunika kwambiri ndichakuti ngati muli ndi chimodzi mwa zizindikiro izi, musanyalanyaze ndipo pitani kwa dokotala kuti akupatseni upangiri.

Kodi n’chiyani chimayambitsa matenda a von Willebrand?

Uwu ndi matenda a majini . Izi zikutanthauza kuti matendawa amayamba chifukwa cha kusintha kwa majini athu. Chifukwa cha kusintha kwa majini kumeneku, thupi lathu silingathe kupanga bwino puloteni yotchedwa von Willebrand factor . Zinthu zimenezi ndi mapuloteni omwe amathandiza magazi athu kuundana.

Chomwe chimapangitsa kuti magazi aziundana chimapezeka mu plasma (gawo lamadzimadzi la magazi athu), ma platelets (maselo omwe amathandiza magazi kuundana), ndi makoma a mitsempha yamagazi . Kawirikawiri, mitsempha yamagazi ikawonongeka, ma platelets amamatira pamalo owonongekawo, ndikupanga magazi kuundana ndikuletsa kutuluka kwa magazi.Von Willebrand factor ndi yomwe imathandiza kuti ma platelet awa amamatirane bwino. Chifukwa chake, mukataya chinthu ichi mokwanira, kapena mukataya kwathunthu, ma platelet sangamatirane bwino. Kenako zimatenga nthawi yayitali kuti magazi aziundana.

Anthu ambiri amalandira matendawa mwa kulandira jini yosinthika kuchokera kwa m'modzi mwa makolo awo . Izi zimatchedwa autosomal dominant inheritance . Ena amatha kulandira jini yosinthika kuchokera kwa makolo onse awiri . Izi zimatchedwa autosomal recessive inheritance , ndipo ndi mtundu woopsa kwambiri wa matendawa. Munthu amene ali ndi jini yosinthikayi ali ndi mwayi wa 50% wopatsira ana awo kusinthaku.

Komanso, nthawi zina matenda a von Willebrand amatha kuchitika ngati vuto la matenda ena, monga khansa , matenda a autoimmune , matenda a mtima, ndi matenda a mitsempha yamagazi.

Kodi madokotala amazindikira bwanji matenda a von Willebrand?

Mukapita kwa dokotala, adzakufunsani kaye za zizindikiro zanu. Angafunsenso ngati pali wina m'banja mwanu amene wakhala ndi zizindikiro zofanana kapena matenda otuluka magazi. Kenako angachite mayeso ena, monga:

• Kuchuluka kwa magazi (CBC): Izi zimayesa kuchuluka kwa maselo ofiira a magazi, mitundu yosiyanasiyana ya maselo oyera a magazi, ndi ma platelet m'magazi anu. Zimayesanso kuchuluka kwa hemoglobin m'maselo ofiira a magazi anu. Anthu ambiri omwe ali ndi matenda a von Willebrand ali ndi CBC yabwinobwino. Komabe, anthu omwe amatuluka magazi ambiri amatha kukhala ndi hemoglobin yochepa komanso kuchuluka kwa maselo ofiira a magazi ochepa.
• Mayeso a kusonkhanitsa ma platelet: Izi zimayesa momwe ma platelet anu amagwirirana kuti athandize kupanga magazi kuundana.
• Mayeso a nthawi yogwiritsira ntchito gawo la thromboplastin (APTT): Izi zimayesa von Willebrand factor ndi zinthu zina zotsekereza magazi zomwe zimathandiza kutsekereza magazi. Ngati kuchuluka kwa zinthuzi kuli kotsika kuposa kwachibadwa, zimatenga nthawi yayitali kuti magazi atseke.
• Kuyesa kwa Prothrombin (PT): Izi zimayesanso zinthu zina zolimbitsa magazi.
• Kuyesa kwa Fibrinogen:Fibrinogen ndi puloteni ina yomwe imathandiza kupanga magazi ambiri.
• Kuyesa kwa Von Willebrand factor antigen: Izi zimayesa kuchuluka kwa mapuloteni a von Willebrand factor m'magazi anu.
• Kuyesa kwa Ristocetin cofactor: Izi zimayesa ntchito ya von Willebrand factor.
• Mayeso a Von Willebrand factor multimers: Izi zimayang'ana kapangidwe ka chinthucho.

Dokotala wanu angafunike kuyezetsa magazi kangapo kuti atsimikizire matendawa, chifukwa zinthu monga kuchuluka kwa mahomoni zimatha kusintha kuchuluka kwa von Willebrand factor m'magazi anu.

Pali mitundu ingapo ya matenda a von Willebrand. Madokotala adzachita mayeso ambiri kuti adziwe mtundu weniweni wa matenda omwe muli nawo. Mitundu iyi ndi iyi:

• Mtundu 1: Uwu ndi mtundu wofala kwambiri. Pakati pa 60% ndi 80% ya odwala ali ndi mtundu uwu. Anthu awa ali ndi kuchuluka kochepa kwa von Willebrand factor m'magazi mwawo. Mwina sangakhale ndi zizindikiro. Ngati ali ndi zizindikiro, zimakhala zochepa kwambiri.
• Mtundu wachiwiri: Mu mtundu uwu, von Willebrand factor sigwira ntchito bwino. Anthuwa amatha kutuluka magazi pang'ono mpaka pang'ono. Pakati pa 15% ndi 30% ya odwala ali ndi mtundu uwu.
• Mtundu wachitatu: Uwu ndi mtundu woopsa kwambiri. Umapezekanso kawirikawiri. Umakhudza pakati pa 5% ndi 10% ya odwala. Anthuwa ali ndi von Willebrand factor yochepa kwambiri m'magazi mwawo, kapena alibe. Izi zingayambitse mavuto aakulu otuluka magazi.

Kodi mankhwala a matenda a von Willebrand ndi ati?

Madokotala amachiza matendawa ndi mitundu yosiyanasiyana ya mankhwala:

• (Desmopressin): Iyi ndi homoni. Imawonjezera kuchuluka kwa von Willebrand factor m'magazi. Iyi ndi njira yodziwika bwino yochizira matendawa.
• Kulowetsedwa kwa Von Willebrand factor: Anthu ena amapatsidwa factor iyi kudzera mu mtsempha kuti asiye kutuluka magazi. Chithandizochi chikhoza kuperekedwa opaleshoni isanachitike. Anthu ena omwe ali ndi matenda aakulu angafunike kulandira chithandizochi nthawi zonse kuti asunge kuchuluka kwa factor m'magazi mwawo kukhala kokhazikika.
• (Ma antifibrinolytics):Mankhwalawa amagwira ntchito poletsa magazi kuundana. Dokotala wanu angakulembereni mankhwala awa ngati mukuchitidwa opaleshoni ya mano kapena ngati mukutuluka magazi ambiri m'mimba.
• Mapiritsi oletsa kubereka: Awa amathandiza anthu omwe akutuluka magazi ambiri m'mimba. Homoni ya estrogen yomwe ili m'mapiritsiwa imawonjezera kuchuluka kwa von Willebrand factor m'magazi.

Kodi ndingachepetse chiopsezo chotenga matendawa?

Izi nthawi zambiri zimakhala zobadwa nazo . Ngati makolo anu ali ndi matendawa, mutha kuwatengera kwa mmodzi kapena onse awiri. Choncho palibe chomwe tingachite kuti tisawatengere.

Ngati ndili ndi vutoli, ndiyenera kuyembekezera chiyani?

Madokotala amatha kuchiza matenda a von Willebrand, koma sangathe kuwachiza kwathunthu . Anthu ambiri ali ndi mtundu woyamba kapena wachiwiri. Amafunika chithandizo chokha ngati avulala kapena akufunika opaleshoni. Anthu omwe ali ndi mtundu wachitatu angafunike chithandizo chamankhwala chopitilira kuti achepetse kutuluka kwa magazi.

Ndili ndi matenda a von Willebrand. Kodi ndiyenera kudzisamalira bwanji ?

Popeza anthu ambiri ali ndi zizindikiro zochepa mpaka zochepa, kukhala ndi matendawa kumatanthauza kuganizira zinthu zingapo:

• Pewani masewera omwe angayambitse kuvulala: Ndi bwino kupewa masewera omwe amakhudza kwambiri thupi, mwachitsanzo mpira wamiyendo, rugby, ndi hockey.
• Uzani madokotala anu onse, kuphatikizapo dokotala wa mano, kuti muli ndi vutoli: kenako akhoza kukonzekera momwe angachepetsere kutuluka magazi pambuyo pa opaleshoni.
• Musagwiritse ntchito aspirin kapena mankhwala okhala ndi aspirin.
• Musagwiritse ntchito mankhwala oletsa kutupa omwe si a steroidal (NSAIDs) , monga ibuprofen, pokhapokha ngati dokotala amene akudziwa kuti muli ndi matenda a von Willebrand wakupatsani.
• Pewani kumwa zakudya zowonjezera zomwe zili ndi vitamini E, mafuta a nsomba, ndi turmeric.
• Ganizirani za chidziwitso cha dokotala: Kuvala chibangili ngati ichi kapena kunyamula khadi lozindikiritsa kungakuthandizeni kupeza chithandizo choyenera chamankhwala pakagwa ngozi.

Kodi ndiyenera kupita kuchipatala mwachangu liti?

Pitani kuchipatala nthawi yomweyo nthawi iliyonse mukatuluka magazi mosalamulirika . Ngakhale ngati ndi kuvulala pang'ono, ngati kutuluka magazi sikusiya, onetsetsani kuti mwapeza upangiri wa dokotala.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala?

Ngati muli ndi matenda a von Willebrand, mungakhale ndi mafunso okhudza momwe matendawa angakhudzire moyo wanu. Nazi mafunso ena omwe mungafunse dokotala wanu:

• N’chifukwa chiyani ndinadwala matendawa?
• Kodi ana anga angalandire matendawa?
• Kodi izi zidzaipiraipira?
• Kodi mankhwala ochizira izi ndi otani?
• Kodi zotsatirapo zake ndi ziti?
• Kodi sindingathe kuchita zinthu zina, monga kuyenda kapena kusewera masewera, chifukwa cha matendawa?

Mwachidule, zinthu zomwe tiyenera kukumbukira ndi izi:

Matenda a Von Willebrand ndi matenda ofala kwambiri, omwe amabadwa nawo chifukwa cha kutsekeka kwa magazi m'thupi. Anthu ambiri amakhala ndi zizindikiro zochepa mpaka zochepa. Akhoza kutuluka magazi m'mphuno pafupipafupi, kapena ngakhale mabala ang'onoang'ono angatenge nthawi yayitali kuti magazi asiye kutuluka. Ena amakhala ndi zizindikiro zoopsa. Mwachitsanzo, akhoza kutuluka magazi m'malo olumikizirana mafupa ndi kupweteka kwa mafupa.

Anthu ena sangadziwe kuti ali ndi vutoli kwa zaka zambiri. Ngati muli nalo, zingakhale zotsitsimula kudziwa chifukwa chake muli ndi mavuto otuluka magazi. Mungakhalenso ndi nkhawa kuti ana anu nawonso adzadwala matendawa. Ngakhale madokotala sangathe kuchiza vutoli, akhoza kulichiza . Angayankhenso mafunso anu okhudza ngati ana anu adzalandira matendawa. Angakupatseninso chidziwitso chomwe mukufuna kuti mukhale ndi matenda a von Willebrand kuti asakulepheretseni kukhala ndi moyo wabwinobwino. Chifukwa chake, musadandaule, ngati mumvetsetsa ndikuwongolera bwino, mutha kukhala nawo bwino.