Mwinanso mungakhale mukuvutika ndi nkhawa pang'ono kapena kuvutika maganizo masiku ano. Pa nthawi ngati imeneyi, dokotala wanu mwina anakupatsani mankhwala otchedwa Vilazodone (omwe amadziwikanso ndi dzina loti Viibryd). Uwu ndi mankhwala omwe amagwiritsidwanso ntchito pochiza kuvutika maganizo. Koma ndi wosiyana pang'ono ndi mankhwala ena. Chifukwa chake lero, tiyeni tikambirane za zinthu zofunika kwambiri zomwe muyenera kudziwa zokhudza mankhwala a Vilazodone awa.
Kodi Vilazodone (Viibryd) imachiza matenda otani?
Mankhwalawa, otchedwa Vilazodone, amaperekedwa makamaka ngati mankhwala a Major Depression Disorder (MDD) . Ichi ndi chomwe nthawi zambiri timachitcha "depression".
Komanso, nthawi zina madokotala amatha kupereka mankhwala awa pa matenda ena. Mwachitsanzo:
- Matenda Oda Nkhawa
- Matenda ovutika maganizo pambuyo pa zoopsa (PTSD)
- Kuvutika Maganizo kwa Bipolar
- Ululu wina wosatha
- Kutentha komwe kumachitika ndi kusamba
Ngakhale kuti Vilazodone sivomerezedwa mwalamulo kuti ichite matenda amenewa, odwala ena akhala ndi zotsatira zabwino nayo, kotero madokotala amalimbikitsa kuti ikhale "yopanda chizindikiro," kutanthauza kuti sivomerezedwa mwalamulo pa matendawo, kuti wodwalayo apindule.
Chofunika kwambiri ndichakuti mankhwalawa amavomerezedwa kwa akuluakulu okha . Saperekedwa kwa ana. Nthawi zambiri, madokotala amapatsa anthu omwe sanapeze zotsatira zabwino pogwiritsa ntchito mankhwala ena oletsa kuvutika maganizo .
Kodi mankhwalawa amagwira ntchito bwanji m'thupi?
Kuti timvetse izi, choyamba tiyenera kudziwa pang'ono za serotonin muubongo mwathu. Mwachidule, serotonin ndi mankhwala omwe amalamulira zinthu zambiri muubongo mwathu, kuphatikizapo momwe timamvera, chisangalalo, ndi tulo. Amakhulupirira kuti anthu omwe ali ndi vuto la kuvutika maganizo ali ndi serotonin yochepa.
Chomwe chimapangitsa Vilazodone kukhala yosiyana ndi ina n’chakuti imawonjezera kuchuluka kwa serotonin m’njira ziwiri.
1. Kugwira ntchito ngati SSRI:Vilazodone ndi mankhwala omwe ali m'gulu la mankhwala otchedwa Selective Serotonin Reuptake Inhibitors (SSRIs) . Serotonin ikatulutsidwa, nthawi zambiri imabwereranso m'maselo a mitsempha . Koma SSRI imaletsa kuyamwanso. Izi zimathandiza kuti serotonin ikhalebe muubongo nthawi yayitali, zomwe zimathandiza kuti maganizo athu akhale bwino.
2. Kugwira ntchito ngati 5-HT1A Partial Agonist: Mankhwalawa amathandizanso ma receptors omwe amalandira mauthenga a serotonin. Izi zimawonjezeranso ntchito ya serotonin.
Chifukwa chakuti imawonjezera kuchuluka kwa serotonin muubongo m'njira zonse ziwiri , Vilazodone ikhoza kukhala yothandiza kwambiri kwa anthu ena.
Kodi Vilazodone (Viibryd) imagwiritsidwa ntchito bwanji?
Mankhwalawa amabwera ngati piritsi. Chofunika kwambiri ndichakuti piritsili lizimwedwa nthawi zonse ndi chakudya. Imwani ndi kapu ya madzi mukatha kudya.
Dokotala wanu nthawi zambiri amayamba kumwa 10mg (mamiligramu) patsiku. Pambuyo pa masiku 7 mutamwa, adzawonjezera mlingo kufika pa 20mg ngati pakufunika kutero. Anthu ena angafunike kuwonjezera mlingo kufika pa 40mg. Komabe, payenera kukhala kusiyana kwa masiku 7 pakati pa mlingo uliwonse. Zonsezi zidzachitika motsatira malangizo a dokotala wanu.
Zimatenga nthawi yayitali bwanji kuti mupeze zotsatira?
Funso limene anthu ambiri amafunsa ndi ili. Mukatha sabata imodzi kapena ziwiri mutayamba kumwa mankhwala, mudzazindikira kuti chilakolako chanu, kugona kwanu, ndi mphamvu zanu zidzachepa pang'ono. Izi zikutanthauza kuti mankhwalawa akuyamba kugwira ntchito. Komabe, zingatenge milungu 6 mpaka 8 kuti vuto la kuvutika maganizo lithe kwathunthu komanso kuti chidwi chanu pantchito chibwererenso. Chifukwa chake khalani oleza mtima ndipo gwiritsani ntchito mankhwalawa.
Chofunika kwambiri: Mankhwalawa ayenera kugwiritsidwa ntchito mosamala, monga momwe ziyenera kukhalira kusiya. Musasiye kumwa mwadzidzidzi popanda upangiri wa dokotala. Kuchita izi kungayambitse zotsatirapo zoyipa (discontinuation syndrome) monga nseru, kusanza, nkhawa, mutu, kumva kuyabwa, komanso thukuta. Ngati musiya kumwa mankhwalawo, muyenera kuchepetsa pang'onopang'ono mlingo. Dokotala wanu adzakufotokozerani momwe mungachitire izi.
Kodi zotsatirapo zake ndi ziti?
Monga mankhwala ena oletsa kuvutika maganizo, Vilazodone ingayambitse mavuto ena. Ena ndi ofala, koma ena akhoza kukhala oopsa. Zinthu monga nseru ndi kuvutika m'mimba zimatha thupi lanu likazolowera mankhwalawo. Koma pali zizindikiro zina zomwe muyenera kuuza dokotala wanu.
| Mtundu wa zotsatira zoyipa | Zizindikiro zomwe zingatheke |
|---|---|
| Zotsatira Zofala | |
| Mavuto a m'mimba | Kutsegula m'mimba (kudzimbidwa), nseru, kusanza. |
| Mavuto ogona | Kusowa tulo kapena kusokonezeka kwa tulo. |
| Zotsatira Zochepa Zofala | |
| Mavuto okhudzana ndi kugonana | Kuchepa kwa chilakolako chogonana, kuvutika kupeza kapena kusunga chigololo, kuchedwa kutulutsa umuna. (Komabe, mankhwalawa ali ndi zotsatirapo zochepa zogonana poyerekeza ndi mankhwala ena a SSRI.) |
| Kukonda/Kusaganiza bwino | Ngati muli ndi matenda a bipolar, mungakumane ndi zizindikiro monga kumva mphamvu zambiri, khalidwe losasamala, komanso kuganiza mofulumira. |
| Zotsatirapo Zazikulu zomwe zimafuna chithandizo chamankhwala mwachangu | |
| Matenda a Serotonin | Serotonin yochuluka m'thupi. Zizindikiro zake ndi monga kugwedezeka, kuona zinthu molakwika, thukuta kwambiri, kugunda kwa mtima mofulumira, kuuma kwa minofu, kunjenjemera, kusanza, ndi kutsegula m'mimba. Izi ndi zadzidzidzi. |
| Maganizo odzipha | Maganizo odzipha kapena kudzivulaza, makamaka mukayamba kumwa mankhwalawo kapena mlingo wake ukasinthidwa. Ngati muli ndi maganizo amenewa, uzani dokotala wanu kapena munthu wina wapafupi nanu nthawi yomweyo. |
| Kugwidwa ndi khunyu | Chiwopsezo chimakhala chachikulu ngati mudadwalapo khunyu kale kapena muli ndi khunyu. |
| Kutuluka magazi kosazolowereka | Chiwopsezo chimakhala chachikulu chikamwedwa ndi mankhwala ochepetsa ululu monga aspirin, NSAIDs (monga Ibuprofen, Diclofenac), kapena mankhwala ena ochepetsa magazi. |
| Glaucoma Yotsekeka ndi Ngodya | Kupweteka kwa maso, kusawona bwino, kuona mphete zamitundu mozungulira magetsi. |
| Kuchepa kwa sodium m'magazi (Hyponatremia) | Mutu, mavuto okumbukira, chisokonezo, kusakhazikika poyenda. Pa milandu yoopsa, kutaya chidziwitso ndi khunyu zimatha kuchitika. |
Machenjezo oyenera kuwadziwa mukamagwiritsa ntchito Vilazodone (Viibryd)
Musanayambe kumwa mankhwalawa, onetsetsani kuti mwauza dokotala wanu za izi.
- Mankhwala ena omwe mukumwa: Uzani dokotala wanu za mankhwala aliwonse, mavitamini, kapena mankhwala azitsamba omwe mukumwa, makamaka aspirin, NSAIDs (monga ibuprofen), ndi mankhwala ena ochepetsa magazi.
- Mimba ndi kuyamwitsa: Onetsetsani kuti mwauza dokotala wanu ngati muli ndi pakati, mukukonzekera kutenga pakati, kapena mukuyamwitsa.
- Matenda ena: Chonde tidziwitseni ngati muli ndi matenda a bipolar, khunyu kapena khunyu, glaucoma, matenda a chiwindi kapena impso.
- Madzi a mphesa: Uzani dokotala wanu ngati mumamwa madzi a mphesa nthawi zonse, chifukwa zingakhudze momwe mankhwalawa amagwirira ntchito.
- Mankhwala a MAOI: Ndi bwino kusagwiritsa ntchito Vilazodone ngati mukumwa mankhwala ena oletsa kuvutika maganizo otchedwa Monoamine Oxidase Inhibitor (MAOI) kapena mwasiya kumwa posachedwapa. Madokotala amalangiza kuti mudikire masiku osachepera 14 mutasiya kumwa MAOI musanayambe kumwa mankhwalawa.
Uthenga Wopita Nawo Kunyumba
- Vilazodone (Viibryd) ndi mankhwala omwe amachiza matenda aakulu ovutika maganizo (MDD) ndipo amawonjezera kuchuluka kwa serotonin mu ubongo m'njira ziwiri.
- Mankhwalawa ayenera kumwedwa nthawi zonse ndi chakudya .
- Zingatenge milungu 6-8 kuti mumve zotsatira zonse za mankhwalawo, choncho khalani oleza mtima ndipo pitirizani kuwagwiritsa ntchito.
- Musasiye kumwa mankhwala mwadzidzidzi pazifukwa zilizonse popanda upangiri wa dokotala.
- Dziwani mavuto aakulu monga serotonin syndrome, maganizo ofuna kudzipha, komanso khunyu. Ngati mukukumana ndi zizindikiro izi, pitani kuchipatala nthawi yomweyo.
- Uzani dokotala wanu za mankhwala ena onse omwe mukumwa komanso matenda ena aliwonse omwe mungakhale nawo musanayambe kumwa mankhwalawo.
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