Umuti mushya uvura hemophilia? Reka twige kuri Qfitlia (fitusiran)?

Niba ufite hemophilia, ushobora kuba uzi ukuntu bibabaza kandi biteye ubwoba kuva amaraso buri gihe, rimwe na rimwe nta mpamvu, kandi ukagorwa no guhagarika kuva amaraso no mu bisebe bito cyane. Ushobora kuba usanzwe ufata imiti yo kuvura kuva amaraso kwawe, cyangwa ushobora kuba ufata imiti yo kubikumira. Ariko, hamwe n'iterambere rya siyansi y'ubuvuzi, ubu hari uburyo bwinshi bwiza kandi bushya bwo kuvura iyi ndwara. None rero uyu munsi, reka tuvuge ku muti mushya, utandukanye. Witwa Qfitlia (fitusiran).

Reka tubanze turebe, kuki kuva amaraso bidahagarara mu gihe cy'indwara ya hemophilia?

Mu magambo make, hari poroteyine zidasanzwe zifasha amaraso yacu kuvura. Ibyo tubyita " ibintu bivura amaraso ." Nk'uko sima ikenewe kugira ngo amatafari afatanye mu kubaka urukuta, ibyo bintu bivura amaraso ni ingenzi kugira ngo amaraso ahagarike kuva. Umuntu urwaye hemophilia aba adafite kimwe muri ibyo bintu bivura amaraso.

• Abantu barwaye hemophilia A badafite ikintu cyitwa Factor VIII.
• Abantu barwaye hemophilia B babura ikintu cyitwa Factor IX.

Iyo ibi bintu bigabanuka, ikorwa ry'indi ntambwe y'ingenzi mu nzira yo kuvura amaraso, yitwa thrombin , riragabanuka. Thrombin ni yo mpamvu nyamukuru ituma amaraso acika kandi agahagarika kuva. Rero iyo thrombin igabanutse, biragorana guhagarika kuva amaraso iyo bibaye. Urabyumva? Ubusanzwe, icyo tumaze igihe kinini dukora nk'ubuvuzi ni ugukora mu buryo bw'ubukorano ikintu kivura amaraso (factor 8 cyangwa 9) kibura mu mubiri wawe hanyuma ukagitera nk'urushinge mu mitsi. Ariko umuti wa Qfitlia tuvuga uyu munsi ukora mu buryo butandukanye rwose.

None se uyu muti mushya witwa Qfitlia (fitusiran) ni uwuhe?

Uyu ni umuti ukora mu buryo butangaje cyane. Twavuze mbere ko amaraso akeneye ikintu cyitwa thrombin kugira ngo agire ubwoya. Mu mibiri yacu, hari indi poroteyine igenzura ikorwa ry'iyi thrombin, ni ukuvuga ko ihagarika ikorwa rya thrombin nyinshi. Yitwa antithrombin .Tekereza muri ubu buryo. Ufite ikintu gituma amaraso abumba (thrombin) mu mubiri wawe gifasha amaraso kubumba. Ariko hari ikindi kintu (antithrombin) kiyigenzura kikayibuza gukora. Muri hemophilia, umusaruro w'ikintu gifasha (thrombin) uba muke mu ntangiriro. Rero iyo ikintu gikingira (antithrombin) gikora neza, amaraso abumba arushaho kugabanuka. Icyo Qfitlia ikora ni ukugabanya ingano ya antithrombin iyibuza. Hanyuma, ingano ya thrombin umubiri wawe ukora mu buryo busanzwe yemererwa gukora neza nta mbogamizi. Ibi bivuze ko ikoresha sisitemu y'umubiri ubwayo kugira ngo itere amaraso kubumba, aho kuguha ikintu gikingira amaraso watakaje. Uyu ni wo muti wa mbere ugabanya thrombin ukoreshwa mu kuvura hemophilia.

Reka dusobanure itandukaniro riri hagati y'ubu buryo bubiri bwo kuvura.

Ushobora gusobanukirwa neza iri tandukaniro ukurikije imbonerahamwe iri hepfo.

Ese uyu muti ukwiriye kuri njye kandi nwukoresha nte?

Niba ufite hemophilia A cyangwa B kandi ukaba ufite imyaka irenga 12, muganga wawe ashobora gusuzuma niba uyu muti ukubereye. Ikintu cy'ingenzi ni uko ushobora no gukoreshwa ku bantu bafite imiti igabanya ubukana bw'indwara zo mu maraso. Ariko, mbere yo gutangira ubu buryo, muganga wawe azakora ibizamini byinshi by'amaraso . 1. Igipimo cya antithrombin: Ibi bipima ingano ya antithrombin mu maraso yawe. Igipimo cya Qfitlia kigenwa hakurikijwe iki gipimo. 2. Imikorere y'umwijima: Umwijima wawe ukurikiranwa mbere no mu gihe cyo kuvurwa. Uyu muti utangwa nk'urushinge munsi y'uruhu (mu buryo bworoshye). Ibi bivuze ko udashyirwa mu mitsi. Wowe cyangwa umuganga wawe mushobora kuwuguha mu rugo nyuma yo kwitoza. Utangwa mu ruhu rwo mu nda, mu itako, cyangwa inyuma y'ukuboko. Ugomba kwirinda ahantu hari ibikomere cyangwa ibikomere. Niba usanzwe ufata ubundi buryo bwo kuvura hemophilia, ushobora gukenera guhagarika cyangwa guhindura ubwo buryo nyuma yo gutangira Qfitlia. Muganga wawe azagusobanurira neza. Ntukareke gufata imiti usanzwe ufata cyangwa ngo ureke gufata Qfitlia utabanje kugirwa inama na muganga. Kubikora bishobora kongera ibyago byo kuva amaraso.

Ese natwe twagombye kumenya ingaruka mbi zishobora kubaho? Twakwirinda dute?

Kimwe n'indi miti iyo ari yo yose, Qfitlia ishobora kugira ingaruka zimwe na zimwe. Ni ngombwa kubimenya no gufata ingamba zo kubikumira.

• • Udukoko tw'amaraso: Kubera ko uyu muti utuma amaraso abumba, ni gake cyane ko amaraso adakenewe atangira kubumba mu mitsi. Muganga wawe azagena igipimo gikwiye cy'urugero rwa antithrombin yawe kugira ngo agabanye ibi byago.

Ni ngombwa cyane gupimisha amaraso buri gihe nk'uko muganga abivuga. Igipimo cya antithrombin gikunze kugenzurwa mu kwezi kwa mbere, ukwa gatatu, ukwa gatanu, n'ukwa gatandatu k'ubuvuzi. Uku ni ko ushobora kumenya ingano ikwiye y'umuti n'uburyo bwo kugabanya iyi ngaruka.

• Imisemburo y'umwijima iri hejuru: Hari abantu bashobora kuba bafite imisemburo y'umwijima iri hejuru. Niyo mpamvu abaganga bakurikirana buri gihe umwijima umeze neza bakoresheje ibizamini by'amaraso .

• Indwara y'imisemburo n'ububyimbirwe bw'imisemburo: Niba ugize ibimenyetso nk'ububabare bukabije mu gifu, isesemi no kuruka , bimenyeshe muganga wawe ako kanya.

• Kwandura: Hari ibyago bike byo kwandura aho watewe inshinge. Kubwibyo, ni ngombwa guhora utera inshinge neza kandi nk'uko muganga yabigutegetse. Isuku nziza, nko gukaraba intoki kenshi, nabyo ni ingenzi.

Ubushakashatsi bwagaragaje ko abantu barwaye hemophilia (baba bafite imiti igabanya ubukana n'abatayifite) bafata Qfitlia bagiraga ibihe byo kuva amaraso bike cyane ugereranyije n'abatafashe imiti iyo ari yo yose yo kwirinda. Nanone, abantu bafite imiti igabanya ubukana bahinduye ubuvuzi bakajya muri Qfitlia bagiraga ibihe byo kuva amaraso bike. Ariko ibuka ko ibi bisubizo bishobora gutandukana bitewe n'umuntu ku wundi.

Ubutumwa bwo kujyana mu rugo

• Qfitlia (fitusiran) ni uburyo bushya bwo kuvura hemophilia A na B bukora mu buryo butandukanye.
• Ibi bikora mu kugabanya ingano ya antithrombin, ibuza amaraso kuvura, aho gutanga ubushobozi buke bwo kuvura umubiri hanze.
• Uyu muti ni urushinge munsi y'uruhu, ntabwo ushyirwa mu mitsi, kandi akenshi utangwa gake cyane, nko rimwe mu kwezi cyangwa buri mezi abiri.
• Muganga wawe azasuzuma niba ubu buryo bw'ubuvuzi bukubereye nyuma yo gupimwa amaraso inshuro nyinshi.
• Kugira ngo wirinde ingaruka mbi, ni ngombwa gupimwa amaraso (cyane cyane antithrombin n'imikorere y'umwijima) buri gihe nk'uko muganga yabigutegetse.
• Irinde guhagarika kuvurwa na Qfitlia nta nama za muganga ku mpamvu iyo ari yo yose.

Hemofiliya, Hemofiliya, Qfitlia, fitusiran, kuvura amaraso, kuva amaraso, ikintu gituma amaraso agwa, antithrombin, kuvura hemofiliya, umuti mushya, ingaruka mbi