Ese nawe ntugira ikibazo cyo guhagarika kuva amaraso no mu gisebe gito? Reka tuvuge ku ndwara ya von Willebrand!

Ese hari igihe ugira agasebe gato kadahagarika kuva amaraso igihe kirekire? Cyangwa ukunda kuva amaraso mu mazuru? Wenda hari umuntu wo mu muryango wawe ufite ibibazo nk'ibyo? Niba ari uko bimeze, iki ni ikintu gishobora kuba ingenzi kuri wewe. Uyu munsi tugiye kuvuga ku ndwara idakunze kugaragara ariko ikunze kugaragara yitwa von Willebrand Disease .

Indwara ya von Willebrand ni iki?

Mu magambo make, indwara ya von Willebrand ni indwara aho amaraso yacu adafata neza, bivuze ko inzira ifasha guhagarika kuva amaraso iba idafite imbaraga. Ibi akenshi biba ari umurage , bivuze ko ababyeyi bashobora kwanduza abana babo indwara. Ariko ntugahangayike, hari uburyo bwo kuyivura. Abaganga bashobora kuguha imiti ifasha muri iyi nzira yo gufata amaraso.

Ni iki kibaho ku muntu urwaye indwara ya von Willebrand?

Umuntu urwaye iyi ndwara ashobora kuva amaraso menshi cyane kurusha uko bisanzwe. Tekereza gato, no gukomereka gato cyangwa gukuramo iryinyo bishobora gufata igihe kirekire kugira ngo amaraso ahagarike. Hari abantu bakunze kuva amaraso mu mazuru. Ku bagore, bashobora kuva amaraso menshi mu gihe cy'imihango, cyangwa se kuva amaraso menshi nyuma yo kubyara.

Mu bihe bikomeye cyane by’iyi ndwara, kuva amaraso rimwe na rimwe bishobora kugaragara mu ngingo cyangwa mu ngingo zoroshye nta mpamvu igaragara. Ibi bishobora gutera kubyimba no kubabara cyane. Ku bandi, bishobora no gutera kubura amaraso , ari byo kubura amaraso .

Iyi ndwara ikunze kugaragara gute?

Iyi ni yo ndwara yo kuva amaraso ikunze kugaragara cyane ku isi. Raporo zimwe na zimwe zigaragaza ko yibasira hafi 1% by'abaturage b'Abanyamerika. Ku isi yose, bivugwa ko hagati y'abantu 23 na 110 kuri miliyoni bashobora kuba bafite iyi ndwara. Ariko, iyi mibare irashobora gutandukana, kuko hari abantu bashobora kugira ibibazo byo kuva amaraso ariko ntibamenyekane barwaye indwara ya von Willebrand . Hari abantu bashobora kuba bamaze imyaka myinshi bafite ibi bibazo, ariko ntibabimenye kugeza igihe byarenze urugero.

Ese indwara ya von Willebrand na hemophilia ni kimwe?

Yego, nubwo byombi ari ibibazo byo kuvura amaraso, indwara ya von Willebrand ni indwara ikunze kugira ibimenyetso bike kandi ikaba idakomeye cyane nka hemophilia . Ariko ibyo ntibivuze ko ari ikintu cyo kwirengagiza.

Ni ibihe bimenyetso by'indwara ya von Willebrand?

Abantu benshi barwaye iyi ndwara bashobora kutagira ibimenyetso na gato , cyangwa bakaba bafite ibimenyetso byoroheje cyane. Ariko, abafite indwara zikomeye bashobora kugira ibimenyetso nka:

• Kuva amaraso mu mazuru : Uku si ukuva amaraso bisanzwe gusa. Gushobora kuva amaraso mu gihe kirenga iminota 10, cyangwa kuva amaraso mu mazuru inshuro zirenga eshanu mu mwaka.
• Kuva amaraso mu gikomere: Kuva amaraso mu gikomere gito cyangwa ikindi gikomere mu gihe kirenze iminota 10.
• Ibisebe: Abantu bafite iyi ndwara bahura n'ibisebe byoroshye cyane. Ibi bisebe ntibiba ku ruhu gusa, ahubwo bishobora kubyimba gato no kuzamuka nk'ikibyimba. Ibi bisebe bishobora kandi kuba binini kurusha igiceri cya rupiya eshanu.
• Kubura icyuma gikozwe mu bwoyaKubura amaraso mu mubiri bitewe n’ibura ry’icyuma: Kubura amaraso mu mubiri ni indwara aho umubiri utagira uturemangingo dutukura duhagije. Kubura amaraso mu mubiri bitewe n’ibura ry’icyuma bibaho iyo umubiri wacu udafite icyuma gihagije cyo gukora hemoglobin . Iki kintu cyitwa hemoglobin, gifasha uturemangingo dutukura gutwara umwuka wa ogisijeni. Rero, iyo dutakaje amaraso menshi, dushobora no gutakaza icyuma no kugira iyi ndwara.
• Kuva amaraso nyuma yo kubagwa: Abantu bafite iyi ndwara bashobora kuva amaraso menshi, ndetse no nyuma yo kubagwa gato, nko gukuramo iryinyo.
• Imihango myinshi: Ku bagore bamwe na bamwe, iyo kuva amaraso mu mihango yabo ari ku rugero runini ku buryo bagomba guhindura pad cyangwa tampon buri saha, cyangwa niba imihango yabo imara iminsi irenga irindwi, bishobora kuba ikimenyetso cy'iyi ndwara.
• Kuva amaraso menshi nyuma yo kubyara cyangwa gukuramo inda.
• Amaraso mu muyoboro: Waba ufite amaraso mu muyoboro wawe cyangwa amaraso umaze kwituma, bishobora kuba ikimenyetso cy'indi ndwara. Kubwibyo , ugomba kujya kwa muganga .
• Amaraso mu nkari (hematuria): Niba ubonye amaraso igihe urimo kunyara, cyane cyane niba amaraso aherekejwe no gushaka kunyara mu buryo butunguranye, bwira muganga ako kanya .

Igikuru ni uko niba ufite kimwe cyangwa byinshi muri ibi bimenyetso, ntubyirengagize ahubwo ujye kwa muganga kugira ngo akugire inama.

Ni iki gitera indwara ya von Willebrand?

Iyi ni indwara iterwa n'uturemangingo . Ibi bivuze ko iyi ndwara iterwa n'impinduka (mutation) mu turemangingo twacu. Bitewe n'izi mpinduka mu turemangingo, umubiri wacu ntushobora gukora neza poroteyine yitwa von Willebrand factor . Izi ni poroteyine zifasha amaraso yacu kubumba.

Iyi von Willebrand factor iboneka muri plasma (igice cy'amazi mu maraso yacu), plaquettes (uturemangingo dufasha kubumba amaraso), no ku nkuta z'imitsi y'amaraso . Ubusanzwe, iyo umutsi w'amaraso wangiritse, plaquettes zifata ku gice cyangiritse, zigakora ikibyimba cy'amaraso kandi zigahagarika kuva amaraso.Von Willebrand factor niyo ifasha izi platelets gufatana neza. Rero, iyo utakaje ibi bintu bihagije, cyangwa ukabitakaza burundu, platelets ntizishobora gufatana neza. Hanyuma bifata igihe kirekire kugira ngo amaraso agire icyo apfa.

Abantu benshi bandura iyi ndwara bakurana na gene yahinduwe n'umwe mu babyeyi babo . Iyi yitwa autosomal dominant inheritance . Abandi bashobora kuragwa gene yahinduwe n'ababyeyi bombi . Iyi yitwa autosomal recessive inheritance , kandi ni yo ndwara ikomeye cyane. Umuntu ufite iyi gene yahinduwe afite amahirwe ya 50% yo kwanduza abana be.

Nanone, rimwe na rimwe indwara ya von Willebrand ishobora kuba ikibazo cy’izindi ndwara, nka kanseri , indwara ziterwa n’ubwiyongere bw’umubiri , indwara z’umutima, n’indwara z’imitsi y’amaraso.

Ni gute abaganga basuzuma indwara ya von Willebrand?

Iyo ugiye kwa muganga, bazabanza kukubaza ibimenyetso byawe. Bashobora kandi kukubaza niba hari umuntu wo mu muryango wawe wigeze kugira ibimenyetso bisa cyangwa indwara zo kuva amaraso. Hanyuma bashobora gukora ibizamini bimwe na bimwe, urugero:

• Umubare wuzuye w'amaraso (CBC): Ibi bipima umubare w'uturemangingo dutukura tw'amaraso, ubwoko butandukanye bw'uturemangingo twera tw'amaraso, na plaquettes mu maraso yawe. Binapima ingano ya hemoglobin mu turemangingo dutukura tw'amaraso yawe. Abantu benshi barwaye indwara ya von Willebrand bafite CBC isanzwe. Ariko, abantu bava amaraso menshi bashobora kugira hemoglobin nkeya n'uturemangingo dutukura duke tw'amaraso.
• Ibipimo byo guteranya platelet: Ibi bipima uburyo platelet zawe zifatana neza kugira ngo bifashe mu gukora ibice by'amaraso.
• Ikizamini cya "activated partial thromboplastin time test" (APTT): Iki kizamini cya "von Willebrand factor" n'ibindi bintu bituma amaraso agwa bifasha mu kuvura amaraso. Iyo urugero rw'ibi bintu ruri hasi ugereranije n'ibisanzwe, bifata igihe kirekire kugira ngo amaraso agwa.
• Ikizamini cya Prothrombin (PT): Iki gipimo kandi gipima ibindi bintu bituma amaraso agwa.
• Ikizamini cya Fibrinogen:Fibrinogen ni indi poroteyine ifasha amaraso kubumba.
• Ikizamini cya Von Willebrand factor antigen: Iki gipimo cy'ingano ya poroteyine ya von Willebrand factor mu maraso yawe.
• Ikizamini cya Ristocetin cofactor: Iki gisuzuma imikorere ya von Willebrand factor.
• Ikizamini cya Von Willebrand factor multimers: Iki gikorwa kireba imiterere y'ikintu.

Muganga wawe ashobora gukenera gukora ibizamini byinshi by'amaraso kugira ngo yemeze ko arwaye indwara, kuko ibintu nk'urugero rw'imisemburo bishobora guhindura urugero rwa von Willebrand factor mu maraso yawe.

Hari ubwoko butandukanye bw'indwara ya von Willebrand. Abaganga bazakora ibizamini byinshi kugira ngo bamenye neza ubwoko bw'indwara ufite. Ubwo bwoko ni ubu:

• Ubwoko bwa 1: Ubu ni bwo bwoko bukunze kugaragara cyane. Hagati ya 60% na 80% by'abarwayi bafite ubwo bwoko. Aba bantu bafite urugero ruto rwa von Willebrand factor mu maraso yabo. Bashobora kutagira ibimenyetso. Iyo babibonye, ​​baba boroheje cyane.
• Ubwoko bwa 2: Muri ubu bwoko, von Willebrand factor ntikora neza. Aba bantu bashobora kuva amaraso make kugeza kuri make. Hagati ya 15% na 30% by'abarwayi bafite ubwo bwoko.
• Ubwoko bwa 3: Ubu bwoko ni bwo bukabije cyane. Bukunze kandi kugaragara cyane. Bugira ingaruka hagati ya 5% na 10% by'abarwayi. Aba bantu bafite urugero ruto cyane rwa von Willebrand factor mu maraso yabo, cyangwa nta na rumwe bafite. Ibi bishobora gutera ibibazo bikomeye byo kuva amaraso.

Ni ubuhe buryo bwo kuvura indwara ya von Willebrand?

Abaganga bavura iyi ndwara bakoresheje ubwoko butandukanye bw'imiti:

• (Desmopressin): Iyi ni imisemburo. Yongera urugero rwa von Willebrand factor mu maraso. Ubu ni bwo buryo bukunze kuvura iyi ndwara.
• Infusion ya Von Willebrand factor: Hari abantu bahabwa iyi factor binyuze mu mitsi kugira ngo bahagarike kuva amaraso. Ubu buvuzi bushobora gutangwa mbere yo kubagwa. Hari abantu bafite indwara zikomeye bashobora gukenera guhabwa ubu buvuzi buri gihe kugira ngo urugero rw'iyo factor mu maraso yabo rugume ruhagaze neza.
• (Imiti igabanya ububabare bw'imitsi):Iyi miti ikora mu gukumira kubyimba kw'amaraso. Muganga wawe ashobora kukwandikira iyi miti niba urimo kubagwa amenyo cyangwa niba urimo kuva amaraso menshi mu gihe cy'imihango.
• Ibinini byo kuboneza urubyaro: Ibi bifasha abafite kuva amaraso menshi mu gihe cy'imihango. Imisemburo ya estrogen iri muri ibi binini yongera urugero rwa von Willebrand factor mu maraso.

Ese nshobora kugabanya ibyago byo kurwara iyi ndwara?

Ibi akenshi biba ari umurage . Niba ababyeyi bawe bafite iyi ndwara, ushobora kuyikuramo umwe muri bo cyangwa bombi. Rero nta kintu twakora ngo tuyibuze.

Niba mfite iyi ndwara, ni iki nkwiye kwitega?

Abaganga bashobora kuvura indwara ya von Willebrand, ariko ntibashobora kuyivura burundu . Abantu benshi bafite ubwoko bwa mbere cyangwa ubwa kabiri. Bakenera kuvurwa gusa iyo bakomeretse cyangwa bakeneye kubagwa. Abantu bafite ubwoko bwa gatatu bashobora gukenera ubuvuzi buhoraho kugira ngo bagenzure kuva amaraso.

Mfite indwara ya von Willebrand. Nkwiye kwiyitaho nte ?

Kubera ko abantu benshi bafite ibimenyetso byoroheje kugeza ku biri hagati, kubana n'iyi ndwara bivuze kuzirikana ibintu bike:

• Irinde ibikorwa bishobora gutera imvune: Ni byiza kwirinda imikino ikomeye, nko gukina umupira w'amaguru, rugby na hockey.
• Bwira abaganga bawe bose, harimo n'umuganga w'amenyo, ko ufite iyi ndwara: bashobora gutegura uburyo bwo kugenzura kuva amaraso nyuma yo kubagwa.
• Ntugakoreshe aspirine cyangwa imiti irimo aspirine.
• Ntugakoreshe imiti igabanya ubukana itari iya steroide (NSAIDs) , nka ibuprofen, keretse ubibwiwe na muganga uzi neza ko urwaye indwara ya von Willebrand.
• Irinde gufata intungamubiri zirimo vitamine E, amavuta y'amafi, na turmeric.
• Tekereza ku ikarita iranga umuganga: Kwambara umukufi nk'uyu cyangwa gutwara ikarita iranga umuntu bishobora kugufasha kubona ubuvuzi bukwiye mu gihe cy'impanuka.

Ni ryari nkwiye kujya mu bitaro byihutirwa?

Jya kwa muganga vuba igihe cyose urimo kuva amaraso mu buryo butunguranye . Nubwo byaba ari imvune nto, niba kuva amaraso bitahagaze, jya kwa muganga.

Ni ibihe bibazo ngomba kubaza muganga?

Niba urwaye indwara ya von Willebrand, ushobora kuba ufite ibibazo ku bijyanye n'uburyo iyi ndwara izagira ingaruka ku buzima bwawe. Dore bimwe mu bibazo ushobora kubaza muganga wawe:

• Kuki narwaye iyi ndwara?
• Ese abana banjye bashobora kuragwa iyi ndwara?
• Ibi bizarushaho kuba bibi?
• Ni ubuhe buryo bwo kuvura ibi?
• Ingaruka mbi z'ubuvuzi ni izihe?
• Ese ntazashobora gukora ibintu bimwe na bimwe, nko gutembera cyangwa gukina siporo, kubera iyi ndwara?

Muri make, ibintu tugomba kwibuka ni

Indwara ya Von Willebrand ni indwara ikunze kugaragara cyane, iterwa no kuvura amaraso mu buryo bw’uturemangingo. Abantu benshi bagira ibimenyetso byoroheje kugeza ku biri hagati. Bashobora kuva amaraso kenshi mu mazuru, cyangwa se gukomereka guto bishobora gufata igihe kirekire kugira ngo amaraso ahagarike. Abandi bafite ibimenyetso bikomeye. Urugero, bashobora kuva amaraso mu ngingo no kubabara ingingo.

Hari abantu bashobora kuba batazi ko bafite iyi ndwara imyaka myinshi. Iyo uyifite, bishobora kugufasha kumenya impamvu ufite ibibazo byo kuva amaraso. Ushobora kandi guhangayikishwa n'uko abana bawe nabo bazayirwara. Nubwo abaganga badashobora kuyivura, bashobora kuyivura . Bashobora kandi gusubiza ibibazo byawe bijyanye no kumenya niba abana bawe bazayirwara. Bashobora kandi kuguha amakuru ukeneye kugira ngo ubane n'indwara ya von Willebrand kugira ngo itakubuza kubaho ubuzima busanzwe kandi bukora. Rero, ntugahangayike, niba uyisobanukiwe kandi ukayifata neza, ushobora kuyibana neza.