Unyango olutsha lwesifo sikaParkinson: Masifunde ngeCarbidopa; iLevodopa Suspension!

Isifo sikaParkinson ngamanye amaxesha sinokwenza kube nzima ukwenza imisebenzi yemihla ngemihla , akunjalo? Ukuphila neempawu ezifana nokuqina nokungcangcazela akulula. Nangona kunjalo, ngokuhambela phambili kwesayensi yezonyango, unyango olutsha luyandiswa ukulawula ezi mpawu. Namhlanje siza kuthetha ngolunye unyango olunjalo. Olu yi-'Carbidopa; iLevodopa Suspension '. Olu alufani neepilisi eziqhelekileyo, kodwa liyeza elinikwa umzimba ngendlela eyahlukileyo kancinci.

Yintoni le yeza? Isebenza njani?

Ngamafutshane, i-'Carbidopa; iLevodopa' liyeza elinikwa ukunciphisa iimpawu zesifo sikaParkinson. Ubusazi na, kukho ikhemikhali ebizwa ngokuba yi'Dopamine' enceda ukulawula iintshukumo zengqondo yethu. Kwisifo sikaParkinson, inqanaba le'Dopamine' engqondweni liyehla. Ngoko ke, eli yeza lonyusa ubungakanani be'Dopamine' engqondweni kwaye linciphisa iimpawu ezifana nokuqina kunye nokungcangcazela emzimbeni.

Oogqirha ngamanye amaxesha banokukunika eli yeza kwezinye iimeko. Ukuba unemibuzo ngalo, buza ugqirha wakho okanye ikhemisti. Elinye igama lemveliso yale yeza yi-'Duopa'.

Ndimele ndimxelele ntoni ugqirha ngaphambi kokuba ndithathe eli yeza?

Ngaphambi kokuba uqale olu nyango, kubaluleke kakhulu ukuxelela iqela lakho lokhathalelo ngezinto ezithile. Ukuba unenye yezi meko zilandelayo, ngokuqinisekileyo kufuneka ubaxelele:

• Isifo seswekile
• Ukuba ungumntu onxila kakhulu
• Imeko yeGlaucoma
• Isifo sentliziyo
• Igazi elonyukayo
• Ukuba ukhe waba neentliziyo ezingaqhelekanga ngaphambili
• Isifo sezintso
• Isifo sesibindi
• Uxinzelelo lwegazi oluphantsi
• Izifo zemiphunga okanye zokuphefumla (umz. i-asthma)
• Utshintsho kwindlela yokuziphatha okanye kwindlela yokuziphatha
• I-Narcolepsy
• Ukuphelelwa ngamandla kokulala
• Iingxaki zesisu okanye zamathumbu
• Iingcinga zokuzibulala, izicwangciso, okanye iinzame; ukuba wena okanye ilungu losapho lwakho likhe lenza njalo
• Ukuba ukhe waba nempendulo engaqhelekanga okanye ye-allergy kwi-levodopa, i-carbidopa, amanye amayeza, ukutya, iidayi okanye izithinteli
• Ukuba ukhulelwe okanye uzama ukukhulelwa
• Ukuba ungumama oncancisayo

Xa ugqirha esazi ngezi zinto, uya kukwazi ukukunyanga ngeyona ndlela ifanelekileyo.

Ndingayisebenzisa njani le yeza?

Ekubeni eli liyeza elikhethekileyo, kubalulekile ukuliqonda kakuhle.

Umthamo wakho wamayeza owumiselweyo uza kulungiswa liqela lakho lezonyango uze ufakwe kwi-'pump' encinci. Uza kuqala uboniswe indlela yokusebenzisa le 'khasethi' kunye nepompo. Kufuneka ufunde `Imiyalelo Yokusetyenziswa' ngononophelo. Liqela lakho lezonyango kuphela eliza kutshintsha umthamo wakho wamayeza, kwaye kuphela xa ekhona. Musa ukuyeka ukuthatha la mayeza okanye utshintshe umthamo ngaphandle kwengcebiso kagqirha wakho.

Eli yeza lifanele lisetyenziswe kubushushu begumbi. Khupha ikhasethi yeyeza efrijini uze uyikhuphe ebhokisini imizuzu engama-20 ngaphambi kokuyisebenzisa. Lisebenzise emva kokuba lifikelele kubushushu begumbi, kungenjalo usenokungafumani idosi echanekileyo yeyeza.

Eli yeza liza kuqhubeka linikwa umzimba wakho iiyure ezili-16. Oku kwenziwa kusetyenziswa ipompo encinci, efana ne-CADD-Legacy 1400. Le mpompi iza kuhambisa iyeza lisuka kwikhasethi liye kwityhubhu yakho ye-PEG-J (ityhubhu ekhethekileyo efakwa esiswini sakho iye emathunjini akho amancinci). Ikhasethi nganye ingasetyenziswa kube kanye kuphela. Musa ukuyisebenzisa kwakhona ikhasethi evuliweyo. Kwakhona, akukhuthazwa ukusebenzisa ikhasethi ngaphezulu kweeyure ezili-16.

Emva kokuba ixesha leeyure ezili-16 leyeza liphelile, susa ipompo kwityhubhu ye-PEG-J. Emva koko, hlambulula ityhubhu yakho ye-PEG-J ngesirinji egcwele amanzi obushushu begumbi. Emva kolu tyando lwemihla ngemihla, kufuneka uthathe iipilisi zakho ze-carbidopa-levodopa zomlomo eziqhelekileyo ebusuku njengoko kuyalelwe. Ukuba awukwazi ukuthatha olu tyando nangasiphi na isizathu, gcina ezinye iipilisi ze-carbidopa-levodopa eziqhelekileyo esandleni.

Eli yeza alinikwa abantwana abancinci.

Kubalulekile: Eli yeza lelakho kuphela. Musa ukwabelana ngalo nabanye.

Ungenza ntoni ukuba uthatha amayeza amaninzi kakhulu?

Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, fowunela iziko lokulawula ityhefu okanye igumbi longxamiseko ngokukhawuleza.

Kuthekani ukuba ndiphoswa lidosi leyeza?

Ukuba nangasiphi na isizathu ukumnika kwakho kuyekiswe kangangeeyure ezingaphezu kwezi-2 ngexesha leeyure ezili-16, fowunela iqela lakho lezempilo kwaye uthathe iipilisi zakho ze-carbidopa-levodopa njengoko kuyalelwe de kuphinde kuqalwe ukumnika kwakhona. Ukuba ukumnika kuyekiswe ngaphantsi kweeyure ezi-2, akufuneki uthathe iipilisi, kodwa iqela lakho lezempilo linokukuxelela ukuba uthathe idosi eyongezelelweyo yokumnika.

Hlala ugcina iipilisi ze-carbidopa-levodopa ezikhutshwa ngoko nangoko kufutshane ukuba awukwazi ukufumana utyando.

Ngawaphi amanye amayeza anokusebenza kunye nale mithi?

Amanye amayeza anokusebenzisana neCarbidopa; iLevodopa. Oku kuthetha ukuba iingxaki zinokubakho xa zisetyenziswa kunye. Ke ngoko, kubalulekile ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka iivithamini, amayeza emifuno, kunye nezongezo.

Musa ukuthatha eli yeza kunye namayeza alandelayo:

• `MAOI` uhlobo lwamachiza (umz. `Marplan`, `Nardil`, `Parnate`)
• `I-Reserpine`
• `I-Tetrabenazine`

La mayeza anokusebenzisana:

• Utywala
• `I-Droperidol`
• `I-Entacapone`
• Izongezo zesinyithi okanye ii-multivitamins ezinesinyithi
• `Isoniazid (INH)`
• `I-Linezolid`
• Amayeza okudakumba, ixhala, okanye ukuphazamiseka kwengqondo
• Amayeza oxinzelelo lwegazi oluphezulu
• Iipilisi zokulala
• 'I-Metoclopramide'
• 'I-Papaverine'
• `I-Procarbazine`
• `I-Tedizolid`
• `Rasagiline`
• `Selegiline`
• `I-Tolcapone`

Olu luhlu lusenokungaphelelanga, ngoko ke xelela ugqirha wakho ukuba uyatshaya, usela utywala, okanye usebenzisa iziyobisi ezingekho mthethweni.

Izinto ekufuneka uzilumkele xa usebenzisa eli yeza

Iqela lakho lezonyango liza kujonga impilo yakho rhoqo ngelixa usela eli yeza. Qiniseka ukuba uyayigcina imiyalelo yakho. Xelela ugqirha wakho ukuba iimpawu zakho aziphucuki okanye ukuba zibonakala zisiba mandundu. Musa ukuyeka ukuthatha iyeza ngaphandle kwengcebiso kagqirha wakho. Ukwenza njalo kunokubangela impendulo eqatha.

Indlela yokunyamekela ityhubhu ye-PEG-J

Iqela lakho lezonyango liza kukuxelela indlela yokunyamekela indawo yakho yetyhubhu ye-PEG-J. Yijonge rhoqo indawo leyo ukuze ubone iimpawu zosulelo. Inkqubo yokufaka ityhubhu ye-PEG-J inokubangela iingxaki zesisu okanye zamathumbu. Ukuba unentlungu esiswini, ukuqhina kwesisu kangangeentsuku ezininzi, isicaphucaphu, ukuhlanza, umkhuhlane, okanye isitulo esimnyama, xelela iqela lakho lezonyango ngoko nangoko.

Ukuba ityhubhu ye-PEG-J iyaqhekeka, ixabene, okanye ibambeke, iimpawu zikaParkinson zinokuba mandundu okanye ukutshintshatshintsha kwemithambo kungabuya. Ukuba oku kuyenzeka, thetha nogqirha wakho.

Ukutya

Ukutya ukutya okuneproteni eninzi kunokuchaphazela indlela eli yeza elisebenza ngayo. Ukuba utshintsha indlela otya ngayo, thetha nogqirha wakho ngaloo nto.

Ukozela kunye nesiyezi

Ungaziva ulele okanye unesizungu. Musa ukuqhuba, ukusebenzisa oomatshini, okanye ukwenza nantoni na efuna ukugxininiswa ude wazi ukuba eli yeza likuchaphazela njani. Musa ukuvuka okanye ukuhlala phantsi ngokukhawuleza, ingakumbi ukuba sele ukhulile. Oku kunokunciphisa umngcipheko wokuba nesizungu kunye nokuwa. Utywala bunokuphazamisa indlela eli yeza elisebenza ngayo. Ngoko ke kuphephe ukusela utywala.

Ukulala ngequbuliso

Xa usela eli yeza, ungalala ngequbuliso ngaphandle kwesilumkiso. Ungalala ngelixa uqhuba imoto, uthetha, okanye usitya. Usenokungaziva ulele ngaphambi kokuba ulale. Ukuba oku kuyenzeka kuwe, xelela ugqirha wakho ngoko nangoko.

Ukuziphatha ngokungxama

Abanye abantu baye baxela ukuba baneminqweno yesondo eyandayo okanye eminye iminqweno enamandla, njengokungcakaza okanye ukutya kakhulu, ngelixa besebenzisa eli yeza. Ukuba ufumana nayiphi na kwezi, xelela ugqirha wakho ngokukhawuleza.

Impilo Yengqondo

Izigulana kunye neentsapho zazo kufuneka ziqaphele ukudakumba okutsha okanye okubi ngakumbi kunye neengcinga zokuzibulala. Ukuba uziva udandathekile okanye uneengcinga zokuzibulala, fowunela iqela lakho lezempilo ngokukhawuleza.

Iziphumo 'zokwaphuka' kunye 'nezokungasebenzi'

Ngaphambi kokuba kufike ixesha lokuthatha idosi yakho elandelayo, ungaziva iyeza liphela (isiphumo 'sokudinwa'). Kwakhona, ngamanye amaxesha iyeza lisenokuyeka ukusebenza imizuzu embalwa ukuya kwiiyure ezimbalwa lize liqale ukusebenza kwakhona ngequbuliso (isiphumo 'sokudinwa'). Ukuba unezi mpawu, xelela ugqirha wakho. Idosi yakho inokufuneka ilungiswe.

Kwabo banesifo seswekile

Ukuba unesifo seswekile, ungafumana iziphumo ezingalunganga xa uvavanya iswekile kumchamo wakho. Thetha nogqirha wakho ngale nto.

Utshintsho kumbala womchamo okanye ukubila

Eli yeza linokubangela ukuba umchamo okanye ukubila kwakho kube mnyama okanye kube bomvu ngombala. Oku akusosizathu sokuxhalaba. Nangona kunjalo, linokungcolisa impahla.

IVithamin B6

Eli yeza lisenokunciphisa amanqanaba akho evithamini B6. Ngoko ke, kufuneka uqiniseke ukuba ufumana ivithamini B6 eyaneleyo ngelixa usebenzisa eli yeza. Thetha nogqirha wakho malunga nokutya kunye neevithamini ozisebenzisayo.

Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?

Njengazo zonke amayeza, le inokuba nemiphumo emibi. Eminye iyingozi, eminye ayibi yingozi kangako.

Iziphumo ebezingalindelekanga ezifuna unyango olukhawulezileyo:

• Iimpendulo ze-allergy - ukurhawuzelela kwesikhumba, ukurhawuzelela, amaqhuqhuva, ukudumba kobuso, imilebe, ulwimi okanye umqala
• Ukuvaleka kwamathumbu - ukuqaqamba okukhulu kwesisu, ukungakwazi ukukhupha indle okanye ukuphuma umoya, ukungabi namdla wokutya, ukuhlanza
• Ukulala ngexesha lomsebenzi wemihla ngemihla
• Utshintsho lwesingqi sentliziyo - ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo, isiyezi, ukuquleka, iintlungu zesifuba, ubunzima bokuphefumla
• Uxinzelelo lwegazi oluphantsi - isiyezi, ukuquleka, umbono ofipheleyo
• Utshintsho kwindlela ovakalelwa ngayo kunye nokuziphatha - ixhala, ukungazinzi, ukudideka, ukubona izinto ezingekhoyo, ukucaphuka, ubutshaba, iingcinga zokuzibulala, ukudakumba
• Iintshukumo ezintsha okanye ezinzima ezingalawulekiyo zobuso, umlomo, okanye umzimba ongasentla
• Intlungu, ukurhawuzelela, okanye ukuba ndindisholo kwamalungu
• Usulelo lwendawo - ukubomvu, ukudumba, ubushushu, okanye intlungu kwindawo yokufaka ityhubhu
• Ukopha kwesisu - indle emnyama enegazi okanye engapheliyo, ukuhlanza izinto ezimdaka ezibonakala ngathi zicoliwe ngekofu
• Intlungu yamehlo ngequbuliso okanye utshintsho lombono (umz., umbono ofipheleyo, ukubona imigca ejikeleze izibane, ukulahleka kombono)
• Unesifiso esingaqhelekanga sokuzibandakanya kwiindlela zokuziphatha ezingacwangciswanga, njengokungcakaza, ukutya kakhulu, ukwenza imisebenzi yesondo, okanye ukuthenga.

Iziphumo ebezingalindelekanga ezihlala zingadingi ngcebiso kagqirha (kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka okanye ziyakhathaza):

• Ukutshintsha kombala wamathe, ukubila, okanye umchamo okubomvu okanye okumnyama
• Isiyezi
• Ukozela
• Intloko ebuhlungu (Oku kubonakala ngathi kuvela kolunye ulwimi, igama elichanekileyo lesiSinhala leli: Intloko ebuhlungu )
• Isicaphucaphu

Olu luhlu lusenokungaphelelanga. Thetha nogqirha wakho ukuze akunike iingcebiso malunga nemiphumo emibi.

Ndingaligcina njani eli yeza?

• Gcina kude nokufikelela kwabantwana.
• Gcina iikhasethi ezingavulwanga efrijini kumaqondo obushushu obuyi-2 ukuya kwi-8 degrees Celsius (36 ukuya kwi-46 degrees Fahrenheit). Musa ukuyiqandisa. Khusela ikhasethi ekukhanyeni kwaye uyigcine ebhokisini ide isetyenziswe. Sebenzisa ngaphambi komhla wokuphelelwa. Lahla amayeza aphelelwe lixesha.
• Lahla ibhokisi emva kweeyure ezili-16 uyikhuphe efrijini, emva kokuyivula, okanye ngexesha lokuyisebenzisa, nokuba isenamayeza. Sebenzisa ngaphambi komhla wokuphelelwa.

Kufuneka kuqatshelwe:Eli nqaku lisisishwankathelo kuphela. Lisenokungabi nalo lonke ulwazi. Ukuba unemibuzo malunga nale yeza, thetha nogqirha wakho, ikhemisti, okanye omnye umboneleli wezempilo.

Umyalezo Wokuya Ekhaya

Kulungile, masiphinde sichaze ezona zinto zibalulekileyo esithethe ngazo:

• Le "Carbidopa; Levodopa Suspension" lunyango oluthile olunceda ukulawula iimpawu zeParkinson's.
• Oku kunikwa umzimba nge `pump` kunye ne `PEG-J tube`.
• Ngokuqinisekileyo kufuneka uxelele ugqirha wakho ngazo naziphi na ezinye iimeko zempilo onazo kunye nazo naziphi na ezinye iziyobisi ozisebenzisayo.
• Landela imiyalelo kagqirha wakho ngqo malunga nendlela yokusebenzisa iyeza kunye nendlela yokunyamekela ityhubhu ye-PEG-J.
• Lumka ngezinto ezinje ngokozela, ukulala ngesiquphe, utshintsho kwimo yakho, kunye nokuziphatha ngokungxama. Ukuba ubona into engaqhelekanga , xelela ugqirha wakho ngoko nangoko.
• Musa ukuyeka ukuthatha iyeza ngequbuliso.
• Ukuba kuvela iziphumo ebezingalindelekanga, ingakumbi ukuba zinzima kakhulu, funa ingcebiso kagqirha ngoko nangoko.

Nangona ukuhlala nesifo sikaParkinson kunokuba nzima, ngonyango olufanelekileyo kunye neengcebiso zonyango, ungazilawula iimpawu zakho kwaye uphile ubomi obungcono. Thetha ngokukhululekileyo nogqirha wakho ngayo nayiphi na imibuzo, uloyiko, okanye iinkxalabo onokuba nazo. Ngaleyo ndlela, unokufumana uncedo olufunayo.

I- Carbidopa, iLevodopa, isifo sikaParkinson, iDopamine, ityhubhu ye-PEG-J, Iziphumo ebezingalindelekanga zamayeza, unyango lukaParkinson