Ngaba ugqirha wakho ukunike iGlasdegib (Daurismo) wena okanye umntu osapho lwakho onesifo somhlaza esibizwa ngokuba yiAcute Myelogenous Leukemia? Liyeza elinamandla kakhulu elinegama elintsonkothileyo. Ngoko ke, le yindlela elula kakhulu neyobuhlobo yokuthetha ngeli yeza, indlela elisetyenziswa ngayo, kunye nento ekufuneka siyilumkele ngakumbi.
Luhlobo luni lonyango iGlasdegib?
Ngamafutshane, iGlasdegib liyeza elijolise kwiiseli zomhlaza kwaye lizithintele ekukhuleni kwazo. Iiseli zomhlaza emzimbeni wethu zifuna iiproteni ezikhethekileyo ukuze zikhule. Oko kwenziwa leli yeza kukuyeka ukusebenza kwezo proteni. Ngale ndlela, xa iiseli zomhlaza zingakwazi ukukhula, sifumana uncedo olukhulu ekulawuleni umhlaza.
Eli yeza lisetyenziswa kakhulu ukunyanga uhlobo lomhlaza wegazi olubizwa ngokuba yi-acute myelogenous leukemia. Ngamanye amaxesha, ugqirha wakho angakunika eli yeza kwezinye iimeko. Ugqirha wakho uza kukuchazela oku ngokweenkcukacha.
Izinto ezibalulekileyo omele uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ekubeni iGlasdegib iliyeza elinamandla kakhulu, kubaluleke kakhulu ukwazisa ugqirha wakho ngezinye izifo onazo. Ukuba unayo nayiphi na kwezi meko zingezantsi, xelela ugqirha wakho ngayo ngaphambi kokuba uqale amayeza.
- Ukuba unesifo sentliziyo.
- Ukuba ukhe waba neentliziyo ezingaqhelekanga ngaphambili.
- Ukuba unembali yezifo ezinxulumene nezihlunu.
- Ukuba unesifo sezintso.
- Ukuba unesifo sesibindi.
- Ukuba inqanaba lee-electrolytes egazini (umz. i-potassium, i-magnesium) liphantsi kakhulu okanye liphezulu kakhulu.
- Ukuba ukhe waba ne-allergy kwi-Glasdegib, amanye amayeza, ukutya, iidayi, okanye izithinteli.
- Ukuba ukhulelwe, okanye uceba ukukhulelwa kungekudala.
- Ukuba ungumama oncancisayo.
Ukufihla olu lwazi kugqirha wakho kunokubeka impilo yakho emngciphekweni ongeyomfuneko, ngoko ungoyiki ukuthetha ngokukhululekileyo ngayo yonke into.
Indlela yokusebenzisa amayeza ngokuchanekileyo?
Kubaluleke kakhulu ukusela amayeza kanye njengoko ugqirha ewayalele, ngomlinganiselo ochanekileyo, ngexesha elifanelekileyo.
- Ginya le pilisi yonke ngeglasi yamanzi. Musa ukuyiqhekeza, ukuyityumza, okanye ukuyihlafuna.
- Ungayithatha le nto nokuba utya okanye ungenakutya. Kodwa eyona nto ibalulekileyo kukuyithatha ngendlela efanayo yonke imihla.Umzekelo, ukuba uqala ukuyithatha emva kokutya, yithathe yonke imihla emva kokutya. Ukuba uqala ukuyithatha ngaphambi kokutya, yithathe yonke imihla ngaphambi kokutya.
- Ungaze uyeke ukuthatha amayeza ngequbuliso ngaphandle kwengcebiso kagqirha wakho.
- Ukuba unika abantwana eli yeza, thetha nogqirha wabantwana ngalo kwaye ulisebenzise kuphela ngokwemiyalelo yakhe.
- Ukuba ngempazamo usele amayeza amaninzi kakhulu: Ukuba ucinga ukuba usele amayeza amaninzi kakhulu, fowunela iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (i-ETU) ekufutshane.
Wenza ntoni ukuba uphoswe yidosi?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula. Nangona kunjalo, ukuba kungaphantsi kweeyure ezili-12 ngaphambi kokuba uthathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.
Zithini iingongoma ezichasene nokusetyenziswa kweli yeza?
I-Glasdegib inokunxibelelana namanye amayeza, ngoko ke kubalulekile ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo.
Musa ukuthatha la mayeza kunye neGlasdegib:
- I-Cisapride
- i-dronedarone
- i-fluconazole
- i-pimozide
- i-posaconazole
- i-saquinavir
- i-thioridazine
La mayeza anokusebenzisana neGlasdegib:
- Amayeza okulwa nentsholongwane kaGawulayo okanye i-AIDS
- Amanye amayeza osulelo lwefungus (umz. i-itraconazole, i-ketoconazole)
- Amanye amayeza okubulala iintsholongwane (umz. i-clarithromycin)
- Amanye amayeza okuxhuzula (umz. i-carbamazepine, i-phenytoin)
- Amanye amayeza abangela ukubetha kwentliziyo okungahambelaniyo (okwandisa ixesha le-QT)
- Amayeza emveli afana neSt. John's Wort
- Ijusi yegrapefruit
Olu luhlu aluphelelanga. Ngoko ke nika ugqirha wakho uluhlu olupheleleyo lwamayeza, iivithamini, amayeza esintu, kunye nezongezo ozithathayo. Ungalibali ukumxelela ukuba utshaya okanye usela utywala.
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa iGlasdegib
- Uvavanyo lwegazi: Kuyimfuneko ukuba kwenziwe uvavanyo lwegazi (umsebenzi wegazi) njengoko ugqirha wakho ekuyalele ngelixa usebenzisa eli yeza.
- Ukukhulelwa: Abafazi bafanele bakuphephe ukukhulelwa ngelixa besebenzisa eli yeza kwaye ubuncinane iintsuku ezingama-30 emva kokuyeka eli yeza. Amadoda afanele akuphephe nokuba nguyise womntwana ngelixa besebenzisa eli yeza kwaye ubuncinane iintsuku ezingama-30 emva kokuyeka eli yeza. Eli yeza linokubangela ingozi enkulu kusana olungekazalwa.
- Ukuncancisa: Xa usela amayeza kwaye ubuncinane iintsuku ezingama-30 emva kokuyeka.Kuphephe ukuncancisa umntwana.
- Ukunikela ngesidoda kunye negazi: Kuphephe ukunikela ngesidoda okanye ngegazi ngelixa usela amayeza kwaye ubuncinane iintsuku ezingama-30 emva kokuyeka.
- Ukuzala: Eli yeza lisenokuchaphazela amandla akho okufumana abantwana. Ukuba uneengxaki malunga noku, thetha nogqirha wakho.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yamayeza
Njengalo naliphi na iyeza, iGlasdegib inokuba nemiphumo emibi. Eminye ifuna ingqalelo ekhawulezileyo, ngelixa eminye ixhaphakile.
| Imiphumela | Inkcazo |
|---|---|
| Izinto ekufuneka uzixele kugqirha wakho okanye kwiSebe leeNgxamiseko (ETU) ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ubunzima bokuphefumla | Ubunzima bokuphefumla. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, umphimbo obuhlungu, izilonda zomlomo. |
| Intlungu yemisipha | Intlungu yemisipha engachazekiyo neqatha. |
| Ukopha okungaqhelekanga | Indle emnyama okanye enegazi; ukuhlanza into ebonakala ngathi yikofu egayiweyo; amabala abomvu eluswini; ukopha empumlweni, kwiintsini, okanye emehlweni; ukugruzuka okungaqhelekanga eluswini. |
| Utshintsho kwisantya sentliziyo | Intlungu yesifuba, isiyezi, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga, ukuziva ubuthathaka, ukuphelelwa ngamandla. |
| Ukudinwa okungaqhelekanga | Ukuziva ubuthathaka kakhulu, ubuthathaka okanye udiniwe ngendlela engaqhelekanga. |
| Xelela ugqirha wakho ukuba iyaqhubeka okanye iyakukhathaza. | |
| Tshintsha incasa | Incasa yokutya iyatshintsha. |
| Ukuqhinwa | Ubunzima bokuphuma esitulweni. |
| Isicaphucaphu | Ukuziva ngathi uhlanza. |
| Ukudumba | Ukudumba kwamaqatha, iinyawo, okanye izandla. |
| Ukudinwa ngokubanzi | Ndiziva ndidiniwe kancinci. |
Ukuba ufumana naziphi na ezinye iimpawu ezingaqhelekanga ezingakhankanywanga kolu luhlu, nceda wazise ugqirha wakho ngazo.
Umyalezo Wokuya Ekhaya
- Soloko uthatha iGlasdegib njengoko ugqirha wakho ekuyalele, ngexesha elifanelekileyo, kwaye kwidosi efanelekileyo.
- Ngaphambi kokuba uqalise amayeza, xelela ugqirha wakho ngawo onke amayeza, iivithamini, amayeza esintu owasebenzisayo, kunye nazo naziphi na iingxaki zempilo onazo.
- Kuphephe ukukhulelwa, ukuncancisa, ukunikela ngegazi, kunye nokunikela ngesidoda ngelixa usela eli yeza kwaye emva kweentsuku ezingama-30 emva kokuyeka. Oku kusebenza kubasetyhini kunye namadoda.
- Ukuba kuvela iziphumo ebezingalindelekanga ezinzulu (umz., ubunzima bokuphefumla, ukopha okungaqhelekanga, iintlungu zesifuba), bona ugqirha ngoko nangoko okanye uye kwiSebe leNgxamiseko (ETU).
- Eli yeza limiselwe wena wedwa. Musa ukwabelana ngalo nabanye abantu nangasiphi na isizathu.
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