Ngaba uva ukudumba ngequbuliso emzimbeni wakho, ingakumbi imilenze, amaqatha, izandla, okanye ubuso? Okanye ngaba ubona igwebu elingakumbi kumchamo wakho kunesiqhelo? Ngamanye amaxesha ezi zinokuba ziimpawu zengxaki kwenye yezona zitho zibalulekileyo emzimbeni wethu, izintso. Namhlanje siza kuthetha ngemeko echaphazela izintso, engaqhelekanga kakhulu, kodwa kubaluleke kakhulu ukuyazi. Oku kubizwa ngokuba yiGlomerulosclerosis.
Ngamafutshane, yintoni iGlomerulosclerosis?
Izintso zethu zifana nee-super filters ezimbini. Zihluza inkunkuma esegazini lethu kwaye ziyikhuphe emzimbeni njengomchamo. Le nkqubo yokucoca yenzeka kwinethiwekhi yemithambo yegazi emincinci
kakhulu ngaphakathi kwezintso. Ezi zizinto esizibiza ngokuba yi-'Glomeruli'.
I-Glomerulosclerosis yimeko apho ezo nethiwekhi zokucoca igazi zincinci
ziba namabala okanye zibe ngqindilili. Kanye njengokuba isilonda senzeka xa ulusu lwethu lonzakele, xa ezi nethiwekhi zokucoca igazi zonakele, ziba namabala. Xa oku kusenzeka, ezo nethiwekhi azikwazi ukusebenza kakuhle.
Ngenxa yoko, iiproteni ezibalulekileyo ekufuneka zibe segazini lethu ziqala ukuvuza ngesihluzo zize ziphume kumchamo . Kwezonyango, le meko siyibiza ngokuba yi- 'Proteinuria' .
Le meko inokuchaphazela abantwana, abantu abadala, kunye nabani na. Nangona kunjalo, ixhaphake kancinci kumadoda.
Yintoni enokubangela le meko?
Kukho iimeko apho kungekho sizathu sithile se-glomerulosclerosis. Kodwa uninzi lwexesha, ibangelwa zezinye iimeko zonyango okanye izinto. Isizathu esiphambili yimeko ebizwa ngokuba yi-'FSGS' (Focal Segmental Glomerulosclerosis). Oku kuthetha ukuba ayizizo zonke izicwili ezihluzwayo kwizintso ezonakeleyo, kodwa ziindawo ezithile kuphela (Focal). Kwaye apho loo monakalo uvela khona, yinxalenye kuphela (Segmental) yesicwili esonakeleyo, hayi isicwili sonke. Nazi ezinye izizathu ezinokuchaphazela le meko ye-'FSGS' kunye ne-Glomerulosclerosis ngokubanzi:
- Isifo seswekile : Isifo seswekile esingalawulekiyo sisona sibangela umonakalo omkhulu kwizintso.
- Ukutyeba kakhulu : Ubunzima bomzimba obugqithisileyo bubeka uxinzelelo olungaphezulu kwizintso.
- Usulelo lwe-HIV :Le ntsholongwane inokonakalisa ngqo iiseli zezintso.
- Izifo ezizikhusela ngokwazo emzimbeni ezifana ne-lupus: Kwezi, inkqubo yomzimba yokuzikhusela ihlasela izintso.
- Isifo seSickle cell: Esi sisifo esibangelwa lufuzo esinokonakalisa izintso.
- I-Reflux nephropathy: Kule meko, umchamo ubuyela umva usuka kwisinyi uye kwizintso, wonakalisa izintso.
- I-Glomerulonephritis: Okwenzekayo apha kukuba iinethiwekhi zokucoca igazi (i-Glomeruli) esizikhankanyileyo ngaphambili ziyadumba, oko kukuthi, ziyadumba.
- Amayeza athile kunye neekhemikhali: Amayeza athile kunye neekhemikhali eziyingozi kwizintso nazo zinokubangela oku.
Zithini iimpawu zoku?
Kwinqanaba lokuqala lesi sifo, kusenokungabikho
zimpawu zicacileyo . Yiyo leyo into eyingozi kakhulu. Kodwa ngokuhamba kwexesha, iimpawu ezithile ziqala ukubonakala. Kubaluleke kakhulu ukuzazi ezi mpawu.
| Uphawu | Icacisiwe ngokulula |
|---|
| Ukudumba | Amanzi ayaqokelelana emzimbeni kuba izintso aziwuhluzi kakuhle. Ungaphawula ukudumba, ingakumbi emilenzeni, emaqatheni, ezandleni, esiswini, nasemacaleni kwamehlo . Oku kudumba kudla ngokungabi nantlungu. |
| Utshintsho kumchamo | Umchamo onegwebu okanye onamaqamza uyenzeka kuba iproteni ikhutshwa kumchamo. |
| Igazi elonyukayo | Xa izintso zonakele, uxinzelelo lwegazi luyanyuka. Ngamanye amaxesha, olu xinzelelo lwegazi luba nzima ukululawula ngamayeza. |
| I-Cholesterol ephezulu | Xa inqanaba leproteni egazini lincipha, isibindi sivelisa i-cholesterol engakumbi. Oku kubangela ukuba inqanaba le-cholesterol egazini linyuke. |
Esi sifo sidla ngokufumaneka xa kusenziwa uvavanyo lwezonyango rhoqo ngenxa yesinye isizathu. Uvavanyo lomchamo lunokubonisa amanqanaba aphezulu eeproteni (iProteinuria) okanye uvavanyo lwegazi lunokubonisa amanqanaba aphantsi eeproteni (iHypoproteinemia).
Ungayixilonga njani ngokuchanekileyo le sifo?
Ekubeni iimpawu ezikhankanyiweyo apha ngasentla zinokubonakala nakwezinye izifo, eyona ndlela ilungileyo yokuqinisekisa le meko kukwenza
i-biopsy yezintso .
Yintoni le Biopsy yezintso?
Ungakhathazeki. Oku kuquka ukuthatha iqhekeza elincinci
kakhulu lesicwili esisezintsoni zakho usebenzisa isixhobo esincinci kakhulu esifana nenaliti. Emva koko, isicwili sihlolwa ngemakroskopu ukuze kubonwe ukuba akukho nanye kwezi zilonda zikhankanyiweyo apha ngasentla.
Ngamanye amaxesha kunokufuneka i-biopsy engaphezulu kwesinye. Ngenxa yokuba olu hlobo lwenxeba alufani kuyo yonke intso, ugqirha unokufuneka athathe iisampulu kwiindawo ezahlukeneyo de afumane indawo eyonakeleyo.
Ukongeza, ugqirha wakho unokucebisa kwakhona iimvavanyo ezilandelayo:
- Uvavanyo lweGlomerular Filtration Rate (GFR): Olu vavanyo lulinganisa indlela ezisebenza ngayo izintso zakho.
- Iskeni se-Kidney Ultrasound: Jonga ubungakanani, imilo, kunye nokuba kukho naziphi na iingxaki ezikwizintso.
- Uvavanyo lwemfuza: Kwezinye iimeko ezingaqhelekanga, ukuze kubonwe ukuba kukho unobangela wemfuza.
Zithini iindlela zonyango zoku?
Ngelishwa,
akukho nyango lwe-glomerulosclerosis. Akukho mayeza athile avunyiweyo ngenxa yaso.
Kodwa ungakhathazeki! Kukho unyango oluninzi olunokunceda ukulawula ukuqhubela phambili kwesi sifo, ukulawula iimpawu, nokuphila ubomi obuqhelekileyo. Injongo ephambili yonyango kukuthintela isifo ukuba singaqhubeki nokuthintela ukungasebenzi kakuhle kwezintso. Unyango luhlala luquka:
- Amayeza oxinzelelo lwegazi: Amayeza afana ne-ACE inhibitors kunye nee-ARB awagcini nje ngokulawula uxinzelelo lwegazi, kodwa akwanceda ekunciphiseni ukulahleka kweproteni kumchamo.
- Amayeza okunciphisa amajoni omzimba: Ii-steroids ezifana ne-Prednisolone kunye nezinye amayeza zinceda ukulawula ukusebenza kwenkqubo yomzimba yokuzikhusela, ukunciphisa ukukhutshwa kweeproteni, kunye nokuphucula ukusebenza kwezintso.
- Amayeza okulawula i-cholesterol (Statins): Alawula amanqanaba aphezulu e-cholesterol.
- I-Diuretics: Susa amanzi agqithisileyo kunye netyuwa emzimbeni kwaye unciphise ukudumba.
- Izinto ezithintela ukugabha kwegazi.
- Utshintsho kwindlela yokuphila: Ukutya ukutya okunetyuwa encinci , ukuzilolonga, kunye nokusela iivithamini kubaluleke kakhulu.
Eyona nto ibalulekileyo kukuba ukuba imeko ibangelwa sisifo esithile, esifana nesifo seswekile okanye ukutyeba kakhulu, isifo esisisiseko kufuneka sinyangwe ngokufanelekileyo. Kubalulekile nokujonga imeko yezintso ngokuvavanya igazi nomchamo rhoqo.
Nangona kukho unyango olupheleleyo, kwezinye iimeko esi sifo sinokuqhubeka siye ekungasebenzini kwezintso. Kwimeko enjalo, i-dialysis okanye ukufakelwa kwezintso kungafuneka.
Umyalezo Wokuya Ekhaya
- I-Glomerulosclerosis yimeko apho iityhubhu ezincinci zokucoca igazi ezikwizintso zonakala, nto leyo ebangela ukuba izintso ziyeke ukusebenza kakuhle.
- Lumka ngeempawu ezinje ngokudumba komzimba, ingakumbi imilenze nobuso, umchamo onamagwebu, kunye noxinzelelo lwegazi oluphezulu.
- Ukuba unale mpawu, bonana nogqirha wakho ngokukhawuleza ukuze akunike icebiso.
- Kufuneka i-biopsy yezintso ukuqinisekisa ukuxilongwa ngokuchanekileyo.
- Nangona ingenakunyangwa ngokupheleleyo, kukho unyango olusebenzayo lokulawula ukuqhubela phambili kwesi sifo kunye nokulawula iimpawu. Kubaluleke kakhulu ukuqala unyango kwangethuba.
I-Glomerulosclerosis IsiSinhala, isifo sezintso, amanxeba ezintso, iiproteni kumchamo, i-proteinuria IsiSinhala, ukudumba kwemilenze, i-biopsy yezintso
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