Ngaba ugqirha wakho ukunike ipilisi ebizwa ngokuba yiGuanidine okanye umntu omaziyo? Usenokuba nomdla kancinci, okanye woyike kancinci, xa usiva eli gama. Kuba eli asiloyeza esiliva rhoqo. IGuanidine liyeza elisetyenziselwa ukunyanga imeko ethile nengaqhelekanga yezonyango. Ke ngoko, kubaluleke kakhulu ukuqaphela oku. Ngoko ke, namhlanje siza kuthetha ngezi pilisi zeGuanidine, iimeko zonyango ezinyangayo, indlela yokuzisebenzisa, kunye nezinto ekufuneka uzilumkele.
Yintoni iGuanidine kwaye inyanga siphi isifo?
Ngamafutshane, iGuanidine liyeza elivuselela imithambo-luvo kwaye liphucula ukusebenza kwemisipha. Ngokwezonyango, likwiqela lamayeza abizwa ngokuba yi-'cholinergic muscle stimulants'.
Eli yeza lisetyenziswa kakhulu ukunyanga imeko engaqhelekanga yokuzikhusela komzimba ebizwa ngokuba yiLambert-Eaton Myasthenic Syndrome (LEMS) .
Masiqonde kancinci malunga nokuba yintoni i-LEMS.
Khawucinge nje, iintshukumo zomzimba wethu zilawulwa yimiyalezo evela engqondweni. Xa le miyalezo ihamba ngemithambo-luvo ize ifikelele kwimisipha, siyakwazi ukuhambisa iingalo nemilenze yethu size sihambe. Kwindawo apho imithambo-luvo kunye nemisipha kudibana khona, ikhemikhali ebizwa ngokuba yi-'Acetylcholine' ikhutshwa kwiziphelo zemithambo-luvo. Xa le khemikhali ifikelela kwimisipha, imisipha iyafinyela, oko kukuthi, iyasebenza.
Kodwa kumntu one-LEMS, inkqubo yomzimba yokuzikhusela ihlasela ngempazamo ezo ziphelo zemithambo-luvo. Ngenxa yoko, ubungakanani be-'Acetylcholine' efunekayo abukhutshwa. Isiphumo kukuba buthathaka kakhulu kunye nokudinwa okubangelwa kukungafumani umyalezo ngokufanelekileyo. Ubuthathaka bemisipha buqheleke kakhulu emilenzeni nasemaqakaleni.
I-Guanidine isebenza ngokuvuselela ukukhululwa kwesithunywa sekhemikhali (i-Acetylcholine) kwiziphelo zemithambo-luvo. Oku kuthetha ukuba inika amandla ukuhamba komyalezo ovalekileyo kwaye inceda izihlunu zisebenze kakuhle kwakhona.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
I-Guanidine liyeza elifanele lisetyenziswe ngononophelo. Kungoko ke, kubaluleke kakhulu ukwazisa ugqirha wakho ngembali yakho epheleleyo yezonyango ngaphambi kokuba umnike eli yeza. Qiniseka ukuba uyamxelela ukuba unayo nayiphi na kwezi meko zilandelayo:
- Isifo sezintso: Ufanele uxelele ugqirha wakho ukuba uneengxaki ezinxulumene nezintso, njengoko izintso zidlala indima enkulu ekususeni eli yeza emzimbeni.
- Isifo sesibindi: Ukuba kukho ubuthathaka ekusebenzeni kwesibindi, khankanya loo nto.
- Iingxaki zeeseli zegazi: Ukuba kuxelwe ukuba uneeseli ezimhlophe zegazi, iiseli ezibomvu zegazi, okanye iiplatelets ezisezantsi egazini lakho, olo lulwazi olubaluleke kakhulu.
- Isifo Sengqondo: Ukuba unyangwa okanye unembali yaso nasiphi na isifo sengqondo, nceda usazise.
- Ii-Allergies: Ukuba une-allergy kwi-guanidine okanye nakweyiphi na enye iyeza, ukutya, okanye idayi.
- Ukukhulelwa okanye ukulindela umntwana: Ukuba ukhulelwe okanye uceba ukukhulelwa, oku kufuneka ukukhankanye.
- Ukuncancisa: Kwazise nogqirha ukuba ungumama oncancisayo.
Ndingayisebenzisa njani le yeza?
Eyona nto ibalulekileyo kukulandela imiyalelo kagqirha wakho xa usebenzisa eli yeza.
- Ginya le pilisi ngeglasi yamanzi.
- Sebenzisa amayeza kanye njengoko kuyalelwe kwileyibhile kagqirha. Musa ukuthatha ngaphezulu okanye ngaphantsi komlinganiselo ochazwe ngugqirha wakho.
- Oku kungenziwa ngaphambi okanye emva kokutya. Nangona kunjalo, ukuba uziva uphazamisekile esiswini, ukukuthatha kunye nokutya kunokunceda ekunciphiseni.
- Ziqhelise ukusela amayeza akho ngexesha elifanayo yonke imihla, ngexesha elifanelekileyo.
- Eyona nto ibalulekileyo: Musa ukuyeka ukuthatha amayeza akho nangasiphi na isizathu ngaphandle kwengcebiso kagqirha wakho. Ukuyeka ngequbuliso kunokubangela ukuba iimpawu zakho zibuye kwaye zibe mandundu.
- Ukuba inikwa abantwana: Xa unika abantwana eli yeza, kubalulekile ukuba ubonane nogqirha wabantwana.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu? (Ukusebenzisa amayeza amaninzi kakhulu)
Ukuba ucinga ukuba ngempazamo uthathe amayeza amaninzi kunokuba ucinga, musa ukulibazisa. Tsalela umnxeba iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Masifunde nangemiphumo emibi kunye nokusebenzisana kwayo.
Njengayo nayiphi na iyeza, iGuanidine inokubangela iziphumo ebezingalindelekanga. Ingadibana nezinye iziyobisi.
Iziphumo ebezingalindelekanga ezinokubakho
Ezinye zezi zinokuba zizinto ezinzulu, ezinye ziqhelekile. Kubalulekile ukuzazi ezi zinto.
| Uhlobo lwesiphumo esibi | Iimpawu |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ezifuna unyango olukhawulezileyo | |
| Iimpendulo ze-allergy | Ukurhawuzelelwa lusu, ukurhawuzelelwa, ukudumba |
| Ubunzima bokuphefumla | Ubunzima bokuphefumla |
| Utshintsho kwisantya sentliziyo | Ukubetha kwentliziyo okukhawulezayo okanye okungaqhelekanga |
| Iimpawu zosulelo | Umkhuhlane, umphimbo obuhlungu |
| Utshintsho lwengqondo | Ukubona okanye ukuva izinto ezingezizo zokwenyani (Iingcamango ezingabonakaliyo) |
| Iingxaki zomchamo | Ubunzima bokuchama okanye utshintsho kubungakanani bomchamo owuvelisayo |
| Ubuthathaka obungaqhelekanga | Ukuziva udiniwe kakhulu kwaye ubuthathaka emzimbeni |
| Iziphumo kwisibindi | Ukutyheli kwamehlo okanye ulusu (njenge-jaundice) |
| Iziphumo ebezingalindelekanga eziqhelekileyo ekufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Iimpawu ngokubanzi | Umlomo owomileyo, isiyezi, intloko ebuhlungu, isisu esibuhlungu, isicaphucaphu/ukuhlanza, urhudo, ukungabi namdla wokutya |
| Iziphumo kwinkqubo yemithambo-luvo | Ukuba ndindisholo, ukurhawuzelela, okanye iintlungu emalungeni, utshintsho kwimo yengqondo |
Amanye amayeza asebenzisana neGuanidine (Ukusebenzisana kwamayeza)
Amanye amayeza owasebenzisayo anokuchaphazela indlela esebenza ngayo iGuanidine. Ngoko ke xelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini kunye neemveliso zezityalo), ingakumbi ukuba usebenzisa nayiphi na kwezi zilandelayo:
- Amanye amayeza asetyenziswa kumhlaza
- Amayeza anikwa ukulawula amasosha omzimba emva kokufakelwa amalungu omzimba
- Amanye amayeza okuxhuzula (umz., `iCarbamazepine`)
- Amayeza okugula ngengqondo afana ne-"Clozapine"
- IiPhenothiazines (umz. iChlorpromazine)
- Amayeza ohlobo lwe-steroid (umz. `i-Prednisone`, `i-Cortisone`)
- 'I-Sulfinpyrazone'
Khumbula ukuba olu luhlu aluphelelanga, ngoko ke ukuze ukhuseleke, kungcono ukuxelela ugqirha wakho ngayo yonke into oyithathayo.
Umyalezo Wokuya Ekhaya
- I-Guanidine liyeza elisetyenziselwa ukunyanga isifo esingaqhelekanga nesithile se-neuromuscular esibizwa ngokuba yiLambert-Eaton Myasthenic Syndrome (LEMS).
- Qiniseka ukuba uxelela ugqirha wakho ngayo yonke imithi oyithathayo, ingakumbi ukuba uneengxaki zezintso, zesibindi, okanye zegazi.
- Akufuneki uqale, uyeke, okanye utshintshe umthamo wamayeza ngaphandle kwengcebiso kagqirha wakho.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinje ngobunzima bokuphefumla, utshintsho kwisantya sentliziyo, ukutyheli kwamehlo, okanye umkhuhlane, funa ingcebiso kagqirha ngoko nangoko.
- Ukuba ukrokrela ukuba usela kakhulu, yiya kwiZiko loLwazi lwePoisons leSizwe okanye kwiSebe leNgxamiseko lesibhedlele (ETU) ngoko nangoko.
- Gcina iyeza kwindawo ekhuselekileyo kubushushu begumbi, kude nokufikelela kwabantwana.
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