Kukho iintsuku apho siziva ngathi asenze nto, size sizive sibuhlungu kakhulu kwaye sithwele umthwalo. Yinto eqhelekileyo leyo. Kodwa ukuba le mvakalelo iqhubeka kangangeeveki ezingaphezu kwezimbini, ukuba yonke into ibonakala ingenathemba kwaye ingenathemba, isenokuba yinto enzulu kunentlungu nje. Sithetha ngokudakumba, okanye njengoko oogqirha beyibiza , 'iMajor Depression Disorder' . Esi sisifo sengqondo esixhaphakileyo ehlabathini. Kodwa ungakhathazeki, awuwedwa ekuthetheni ngale nto kwaye ucela uncedo.
Yintoni kanye kanye ingcinezelo?
Ngamafutshane, ukudakumba sisifo sengqondo esichaphazela indlela ovakalelwa ngayo. Asikuko ukugula ngengqondo okanye into oyicingayo. Yimeko yokwenyani yezonyango. Nangona kungekho sizathu sithile sifunyenweyo, izazinzulu zikholelwa ukuba sinokubangelwa zizinto ezahlukeneyo, kuquka utshintsho lweekhemikhali engqondweni, iimpembelelo zemfuza, kunye neziganeko zobomi ezibuhlungu.
Ukuze ufumanise esi sifo, kufuneka ube neempawu ezilandelayo ubuncinane iiveki ezimbini zilandelelana:
- Usizi olunzulu kunye nokungabi nanto okubonakala ngathi kuhlala imini yonke.
- Ukulahlekelwa ngumdla kwizinto obukade uzonwabela.
- Ndiziva ndidiniwe kakhulu, ndingenabomi.
- Ubuthongo buyatshintsha (ukulala kakhulu okanye ukungalali konke konke).
- Utshintsho ekutyeni (ukulahlekelwa yinkanuko okanye ukutya kakhulu).
- Ukuzijongela phantsi, ukuziva ungento yanto.
- Ubunzima bokugxila.
Into ebalulekileyo kukuba le yimeko enokulawulwa ngcono ngonyango, ngoko ke akukaze kube kudala ukucela uncedo.
Unyango lwalusenziwa njani ngaphambili? Iindlela zonyango lwakudala
Kangangexesha elide, malunga neminyaka engama-50, xa kufikwa ekunyangeni ukudakumba, izazinzulu bezigxile kakhulu kwiikhemikhali ezikwiingqondo zethu ezibizwa ngokuba zii-neurotransmitters. Zicinge 'njengemiqondiso' evumela iiseli zemithambo-luvo ezikwiingqondo zethu ukuba zithethe. Ukuba ezi mpawu azisebenzi kakuhle, imeko yethu yeemvakalelo inokuphazamiseka.
Amayeza amaninzi amadala, abizwa ngokuba 'zii-antidepressants', enzelwe ukulinganisela umsebenzi wee-chemical messengers ezintathu ngokukodwa : i-serotonin, i-norepinephrine, kunye ne-dopamine . La mayeza abe neziphumo ezilungileyo kubantu abaninzi, kodwa hayi kubo bonke abantu.
Kutheni le nto eli yeza lingasebenzi kubo bonke abantu?
Nantsi ingxaki. Malunga nabantu abathathu kwabalishumi abanesifo sokudakumba abafumani kuphumla kangako nokuba batshintshe kungekuphela nje iyeza elinye, kodwa ababini. Oogqirha bayibiza le meko ngokuthiIbizwa ngokuba yi-'Theatment-Resistant Depression'.
Yiyo loo nto, kwiminyaka engamashumi amabini edlulileyo okanye ngaphezulu, izazinzulu ziye zatshintsha ngokupheleleyo indlela ezicinga ngayo ngoxinzelelo. Ziye zaqonda ukuba uxinzelelo aluyongxaki nje yezo zithunywa ezintathu zeekhemikhali esithethe ngazo ngaphambili. Ibhayoloji yengqondo iyinkimbinkimbi kakhulu kunoko. Kwaye oko kuvula indlela entsha yokufumana amayeza amatsha.
Makhe sijonge umahluko phakathi konyango lwamandulo nolwanamhlanje ngale ndlela.
| Uphawu | Unyango oludala (uninzi lweziyobisi ezithintela uxinezeleko) | Iindlela zonyango zamva nje |
|---|---|---|
| Injongo ephambili | Ii-neurotransmitters ezifana ne-serotonin, i-norepinephrine, kunye ne-dopamine | Ezinye iinkqubo zokubonisa kunye neesekethe ze-neural engqondweni, ezifana nee-GABA receptors |
| Ixesha leziphumo | Kungathatha iiveki ezimbalwa okanye inyanga. | Iziphumo ezikhawulezayo kwiiyure okanye kwiintsuku ezimbalwa |
| Indlela yokunika | Iipilisi ezithathwa imihla ngemihla rhoqo | Ukufakwa kwe-IV okanye i-spray ekhethekileyo yempumlo |
Iyeza lamva nje elisebenza ngokukhawuleza
Ingcamango yokuba ukudakumba kuthatha iiveki okanye iinyanga ukuze kuphole iyatshintsha. Unyango olutsha nolukhawulezayo luye lwandisa imida yoko kunokwenziwa kweli candelo.
Iyeza elikhethekileyo lokudakumba emva kokubeleka
Ngo-2019, iyeza elibizwa ngokuba yiBrexanolone lavunywa. Lenzelwe ngokukodwaUxinzelelo emva kokubeleka luhlobo lwesifo esiphambili sokudakumba.
- Isebenza njani? Nangona ingacaci ngokupheleleyo indlela esebenza ngayo, yikopi eyenziweyo ye-steroid eveliswa yimizimba yethu ngokwendalo. Isebenza ngokuchaphazela ii-receptors ezikwingqondo ezibizwa ngokuba yi-GABA, ezinceda ekulawuleni imeko yethu yeemvakalelo.
- Ulithatha njani? Eli yeza alilula ukulisebenzisa njengezinye izidambisi-ntlungu. Lifanele linikwe njenge-IV infusion (njenge-saline) kangangeeyure ezingama-60 , esibhedlele, phantsi kweliso likagqirha.
- Iziphumo? Okumangalisayo kukuba, iziphumo zikhawuleza kakhulu. Iimpawu zakho zokudakumba zisenokuqala ukwehla kwangoko nje ukuba unyango lugqityiwe.
Ngokufanayo, uphando luyaqhubeka kwamanye amayeza amatsha anokubonelela ngeziphumo ezikhawulezayo zokudakumba okunganyangekiyo kunyango, oko kuthetha ukuba sinokulindela unyango olungcono nangakumbi kwixesha elizayo.
Ngoko ke, ndimele ndenze ntoni?
Ukuba ufunda eli nqaku kwaye unezinye zezi mpawu, nceda ungabi wedwa. Musa ukugqiba kwelokuba unesifo ngokujonga kwi-intanethi.
Eyona nto ingcono onokuyenza kukubona ugqirha wakho omthembileyo uze uthethe ngale nto.
Ngugqirha wakho kuphela onokuxilonga imeko yakho ngokuchanekileyo aze amisele unyango olulungele wena. Oku kungabandakanya amayeza aqhelekileyo, ingcebiso/unyango, okanye ukuthunyelwa kwingcali yezempilo yengqondo ukuba kuyimfuneko. Khumbula, ukucela uncedo luphawu lwamandla.
Umyalezo Wokuya Ekhaya
- Ingxaki Yokudandatheka Okukhulu ayibobuthathaka, yimeko yokwenyani yezonyango ekufuneka inyangwe.
- Nangona amayeza amadala enceda abantu abaninzi, awasebenzi kubo bonke abantu.
- Ngokuhambela phambili kwesayensi, ngoku kukho unyango lwanamhlanje olujolise kwezinye iinkqubo zokubonisana engqondweni kwaye lubonelele ngeziphumo ezikhawulezayo.
- Kukho unyango olusebenza kakhulu nolukhawulezayo ngoku olufumanekayo kwiimeko ezithile, ezinje ngokudakumba emva kokuzalwa.
- Ungaze uzixilonge okanye uzinyange. Ukuba ukrokrela ukuba unesifo sokudakumba, funa ingcebiso kagqirha ngoko nangoko.
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