Njengoko ubhubhane weCovid-19 uqhubeka, besisoloko sisiva amagama amatsha kunye neentlobo ezintsha zamayeza, akunjalo? Phakathi kwawo, usenokuba ukhe weva igama elithi 'Monoclonal Antibodies'. Usenokuba ukhe weva ugqirha wakho ethetha ngale nto, okanye usenokuba uyibonile ezindabeni. Ngoko ke, yintoni kanye kanye le ndlela yonyango? Kwenzeka ntoni ngayo? Ngaba le yindlela yonyango yomntu wonke? Masithethe ngayo ngokulula nangokucacileyo.
Zithini iiMonoclonal Antibodies (mAbs)?
Ngamafutshane, ezi ziiproteni ezikhethekileyo ezenziwe kwilebhu, oko kukuthi, kwilebhu. Zenzelwe ukusebenza njengee-antibodies eziveliswa yimizimba yethu ngokwendalo.
Khawuthelekelele, xa imizimba yethu igula, umzekelo, xa sifumana umkhuhlane, imizimba yethu yenza amajoni amancinci abizwa ngokuba 'zii-antibodies' ukulwa nentsholongwane eyibangeleyo. La majoni ayahamba aye kuyibamba loo ntsholongwane aze ayithintele ukuba ingasasazeki emizimbeni yethu. Yiloo nto eyenziwa zezi Monoclonal Antibodies (mAbs). Xa zinikwa imizimba yethu zivela ngaphandle, ezi antibodies zenziwe ngokwenziwa zingena emizimbeni yethu, zifumane intsholongwane ebangela iCovid-19 (SARS-CoV-2), ziyibambe, kwaye zincede ekuyithinteleni ekonakaliseni iiseli zomzimba wethu.
Ukuchaneka, oku kufana nomkhosi oqeqeshwe ngokukodwa olethwe uvela ngaphandle ukuze ulwe nesifo.
Olu nyango lusebenza njani ngaphakathi emzimbeni?
Ukuze siqonde oku, masithathe umzekelo omncinci. Khawucinge ukuba intsholongwane yeCovid-19 lisela elizama ukungena ezindlwini ezibizwa ngokuba ziiseli emizimbeni yethu. Eli sela linesitshixo esikhethekileyo sokuvula iingcango zeeseli zethu. Ngokwesayensi, esi sitshixo sibizwa ngokuba yi -'spike protein' . Le ntsholongwane isebenzisa esi sitshixo ukungena kwiiseli zethu kwaye ibangele isifo.
Ngoku, into eyenziwa leli yeza elibizwa ngokuba yiMonoclonal Antibody kukuzincamathelisa kwisitshixo sesela (iproteni yespike) size siyivale ukuze singasebenzi. Kufana nokuncamathelisa itshungama kwindawo yokuvula isitshixo. Emva koko intsholongwane ayinakungena kwiiseli zethu. Oko kuthetha ukuba, amandla entsholongwane okwanda emzimbeni, oko kukuthi, ukusasazeka, ayancitshiswa. Oku kunceda kakhulu ekuthinteleni isifo ukuba singabi yingozi. Uyaqonda?
Kodwa kukho into ebalulekileyo. Intsholongwane yeCovid-19 itshintsha rhoqo uhlobo lwayo. Kukho iintlobo ezintsha ezivelayo. Olu nyango lusenokungasebenzi kangako kwezinye iintlobo ezintsha. Ke ngoko, iingcebiso zezi ndlela zonyango nazo ziyatshintsha ngamanye amaxesha. Ngoko ke ukuba ufuna ukwazi nantoni na ngale nto, eyona nto ilungileyo nekhuselekileyo kukuthetha nogqirha wakho, ungathembi nje ulwazi olukwi-intanethi.
Ngubani onikwa olu nyango?
Olu asilonyango lomntu wonke ofumana i-COVID.. Ngokwesiqhelo inikwa kuphela abantu abasengozini enkulu yokuba ne-COVID-19 enzima . Inikwa nakwiintsuku zokuqala emva kokuba iimpawu ziqalile. Kungcono inikwe ngaphambi kokuba imeko ibe mandundu kakhulu ukuba ingadinga ukulaliswa esibhedlele.
Makhe sibone ukuba zeziphi iingozi ezicetyiswayo kolu nyango.
| Iqela loMngcipheko | Inkcazo |
|---|---|
| Abantu abadala | Ngokwesiqhelo abantu abangaphezu kweminyaka engama-65 ubudala. |
| Abantu abatyebe kakhulu | Abo bane-body mass index ephezulu (BMI). |
| Abantu ababuthathaka kwi-immune system | Umzekelo, abantu abafumana unyango lomhlaza, abo bafakelwe amalungu omzimba, okanye abo banezinye izifo ezinciphisa amajoni omzimba. |
| Abantu abanezinye izifo ezingapheliyo | Abantu abaneengxaki ezifana nesifo seswekile esingalawulekiyo, isifo sezintso esinganyangekiyo, isifo sentliziyo esinzulu, kunye nesifo semiphunga esinganyangekiyo. |
| Oomama abakhulelweyo | Kwezinye iimeko, olu nyango lunokuthathwa ingqalelo nakoomama abakhulelweyo. |
Eyona nto ibalulekileyo kukuba ukuze olu nyango luphumelele, kufuneka luthathwe kwiintsuku zokuqala emva kokuqala kweempawu . Ngoko ke ukuba une-COVID kwaye uwela kweli qela lomngcipheko, musa ukulibazisa kwaye uthethe nogqirha wakho ngokukhawuleza. Uza kuqwalasela ubudala bakho, imeko yempilo, kunye nohlobo lwesifo ukuze abone ukuba olu nyango lukulungele na.
Ngaba kukho naziphi na iziphumo okanye iingozi ngolu nyango?
Ewe. Njengayo nayiphi na iyeza, olu nyango lunokubangela ezinye iziphumo ebezingalindelekanga. Nangona kunjalo, ezi zinto azenzeki kuwo wonke umntu. Ezona zixhaphakileyo zezi:
- Ububomvu, ukudumba, okanye intlungu kwindawo yokufakwa kwe-intravenous.
- Umkhuhlane, ukuziva ubanda, iintlungu zomzimba.
- Intloko ebuhlungu, isicaphucaphu, okanye ukuhlanza.
- Amaxesha amaninzi, iimpembelelo ezinkulu ze-allergy zinokwenzeka. Ezi zinokubandakanya ubunzima bokuphefumla, iintlungu zesifuba, ukubetha kwentliziyo ngokukhawuleza, kunye nokudumba kobuso okanye umphimbo.
Ngenxa yesi sizathu, olu nyango lunikwa esibhedlele. Uza kugcinwa phantsi kweliso likagqirha kangangeyure emva kokuba unikwe iyeza, kwaye naziphi na iimpembelelo ze-allergy kufuneka zinyangwe ngokukhawuleza.
Khumbula, ugqirha wakho uza kugqiba ekubeni akunike olu nyango kuphela xa eqinisekile ukuba iingenelo kuwe zingaphezulu kweengozi.
Umyalezo Wokuya Ekhaya
- IiMonoclonal Antibodies (mAbs) ngamayeza akhethekileyo enziwe kwilebhu asebenza njengee-antibodies zendalo zomzimba wethu.
- Oku kuyayithintela intsholongwane yeCovid-19 ukuba ingangeni kwiiseli zomzimba wethu.
- Olu nyango lunikwa kuphela abantu abasengozini enkulu yokufumana izifo ezinzulu ukuba bafumana i-COVID-19 (umz., abantu abadala, abo banezifo ezingapheliyo).
- Ukuze ufumane iziphumo ezilungileyo kunyango, kufuneka luthathwe kwiintsuku zokuqala emva kokuqala kweempawu.
- Ukuze ubone ukuba olu nyango lufanelekile kuwe okanye kumntu othile kusapho lwakho, qiniseka ukuba uxoxa ngalo nogqirha wakho. Musa ukusekela izigqibo zakho kulwazi olufumaneka kwi-Intanethi kuphela.
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