Ngaba ngamanye amaxesha uziva nje iintlungu emathanjeni nasemalungeni akho? Okanye uziva ngathi intloko yakho iyakhula kancinci kwaye imilenze yakho iya imfutshane njengoko ukhula? Usenokucinga ukuba ezi zizinto eziqhelekileyo zokwaluphala. Kodwa ngasemva kwezi zinto, kusenokuba yimeko efihlakeleyo, engathethwayo ebizwa ngokuba yi-'Paget's Disease of the Bone'. Eli gama lisenokuba litsha kuwe. Kodwa le yimeko enokuchaphazela impilo yamathambo ethu buthule. Namhlanje, siza kuthetha ngayo ngokulula, ngendlela onokuyiqonda.
Ngamafutshane, yintoni iPaget's Disease of the Bone?
Ukuze siqonde oku, masiqale sijonge indlela amathambo ethu asebenza ngayo. Amathambo ethu asizozinto ezingaphiliyo nje kuphela. Ziithishu eziphilayo ezihlala zizihlaziya, zisusa iiseli ezindala kwaye zenze ezintsha. Le nkqubo siyibiza ngokuba kukuguqulwa kwamathambo. Kufana nokudiliza indlu endala nokwakha entsha, enamandla endaweni yayo. Oku kubaluleke kakhulu ekugcineni amathambo ethu eqinile.
Nangona kunjalo, kumntu onesifo sikaPaget samathambo, le nkqubo ayisebenzi kakuhle. Nantsi into eyenzekayo:
1. Ukuqhekeka ngokukhawuleza kwethambo elidala: Iiseli zamathambo amadala ziqhekeka ngokukhawuleza kunesiqhelo.
2. Ukwakheka okungaqhelekanga kwethambo elitsha: Umzimba ukhawuleza wenze ithambo elitsha ukuze uzalise umsantsa. Nangona kunjalo, ithambo elitsha elenziweyo libuthathaka, aliqhelekanga, likhulu, kwaye libuthathaka. Imo yalo nayo yahlukile.
Ngamafutshane, kufana nento eyenzekayo xa umdlali we-bass onamava engxama emsebenzini angawaziyo. Nokuba wakha udonga, luya kolulwa, lube buthathaka, kwaye luqhekeke ngokukhawuleza. Yiloo nto eyenzekayo kumathambo ethu kwesi sifo. Ngenxa yoku, amathuba okuba amathambo aqhekeke ngokulula (aqhekeke) kunye nentlungu yamalungu (i-arthritis) aphezulu kakhulu. Elinye igama lesi sifo yi-`(Osteitis Deformans)`.
Ingaba esi sifo ngumhlaza? Musa ukusibhidanisa nesinye 'isifo sikaPaget'!
Le yingxaki abantu abaninzi abanayo. Abanye abantu bayoyika ngenxa yokufana kweli gama.
Khumbula ngokucacileyo: Isifo sikaPaget samathambo asingomhlaza.
Nangona kunjalo, kukho into encinci ekufuneka uyazi apha. Amathuba ambalwa kakhulu , oko kukuthi, xa amathuba ephantsi kakhulu, kukho ithuba elincinci lokuba umhlaza wamathambo (`osteosarcoma`) unokuvela kwithambo elichaphazelekileyo sisifo sikaPaget. Kodwa kubalulekile ukukhumbula ukuba oku kunqabile kakhulu.
Kukho ezinye izifo ezininzi ezibizwa ngokuba yi-'Paget's', kodwa azinanto yakwenza nesi sifo samathambo.
- Isifo sikaPaget sebele: Olu luhlobo olungaqhelekanga lomhlaza webele oluvela kwindawo yeengono.
- Isifo sikaPaget se-vulva:Olu luhlobo olungaqhelekanga lomhlaza wesikhumba oluvela emlonyeni welungu lobufazi kubafazi.
Ngoko ke, qonda ukuba nangona ezi zifo zintathu zinamagama afanayo, ezi ziimeko ezintathu ezahlukeneyo zezonyango ezingenanto yakwenza.
Ngubani osengozini enkulu yokuhlaselwa sesi sifo?
Izazinzulu azikafumani unobangela ochanekileyo wesi sifo, kodwa kukholelwa ukuba sibangelwa kukudibana kwezinto ezimbini zemfuza , oko kukuthi, iimpembelelo zelifa, kunye nezinto ezisingqongileyo .
Le theyibhile ingezantsi idwelisa ezinye zezinto eziphambili ezibangela umngcipheko ekukhuleni kwesi sifo.
| Into enobungozi | Inkcazo |
|---|---|
| Ubudala | Abantu abangaphezu kweminyaka engama-50 ubudala basengozini enkulu yokuhlaselwa sesi sifo. Le ngozi iyanda xa abantu bekhula. |
| Imbali yoSapho | Ukuba omnye wezalamane zakho ezisondeleyo (umama, utata, umntakwenu) unale sifo, nawe unokuba naso. |
| Imvelaphi yeSizwe | Esi sifo sixhaphake kakhulu kubantu baseYurophu, ingakumbi amazwe afana neNgilane, i-Itali, neSpain. |
| Isondo | Amadoda anamathuba amancinci okufumana esi sifo kunabafazi. |
Zithini iimpawu zesi sifo? Uzibona njani?
Into emangalisayo ngesi sifo kukuba abantu abaninzi abanazo iimpawu konke konke . Okanye baneempawu ezincinci kakhulu nezingenamsebenzi. Ngenxa yesi sizathu, esi sifo sidla ngokufunyanwa ngengozi xa kwenziwa uvavanyo lwe-X-ray okanye lwegazi ngesinye isizathu.
Nangona kunjalo, ukuba iimpawu ziyabonakala, zinokwahluka ngokuxhomekeke kwithambo elichaphazelekileyo. Iimpawu eziqhelekileyo ziquka:
- Intlungu yamathambo okanye amalungu: Olu lolona phawu luphambili noluqhelekileyo. Lunokuvakala njengentlungu engapheliyo, enzulu kwithambo elichaphazelekayo okanye ilungu elikufutshane.
- Ukukhubazeka kwamathambo: Ekuhambeni kwexesha, imilo yamathambo inokutshintsha. Umzekelo, ukuba ukhakhayi luchaphazelekile, intloko inokuba nkulu kancinci, okanye ukuba imilenze ichaphazelekile, imilenze inokugoba.
- Ukwaphuka kwamathambo: Ngenxa yokuba amathambo amatsha abuthathaka, anokwaphuka lula nokuba awile kancinci okanye enze ingozi.
- Intloko ebuhlungu kunye nokulahlekelwa kukuva: Ukuba isifo sichaphazela amathambo entloko, ukuqina kwala mathambo kunokubangela ukucinezelwa kwemithambo-luvo, iintloko ezibuhlungu, kunye nokulahlekelwa kukuva.
- Intlungu yomqolo: Ukuba umqolo uchaphazelekile, iimpawu ezifana neentlungu zomqolo kunye nokungakhululeki emilenzeni zinokubakho.
Ugqirha uxilonga njani esi sifo?
Njengoko kukhankanyiwe apha ngasentla, oku kudla ngokufunyaniswa ngengozi. Ugqirha wakho angakuthumela kwezi mvavanyo ukuba uneempawu okanye ukuba uvavanyo ngesinye isizathu lubangela ukurhaneleka.
- Uvavanyo lwegazi lweAlkaline Phosphatase (ALP): Olu luvavanyo lokuqala olunika ingcaciso. Le enzyme ebizwa ngokuba yi-'ALP' iveliswa xa iiseli zamathambo zisakhiwa. Kwisifo sikaPaget, kuba inkqubo yokwakheka kwamathambo igqithisile, inqanaba le-'ALP' egazini liphezulu kakhulu.
- Ii-X-reyi: Eyona ndlela ilungileyo yokuqinisekisa isifo kukusebenzisa i-"X-reyi". Imifanekiso ye-"X-reyi" ingakwazi ukwahlula ngokucacileyo amathambo achaphazelekileyo kwamanye amathambo aphilileyo. Ungabona indlela akhule ngayo ngobukhulu kwaye atshintshe ngayo imo.
- Ukuskena Amathambo: Oku kwenzelwa ukubona ukuba ngawaphi amathambo emzimbeni achatshazelwa sesi sifo kunye nokuba sibi kangakanani. Idayi encinci ye-radioactive ifakwa emthanjeni kwaye iindawo ezinesifo zibonwa 'njengeendawo ezikhanyayo' xa ziskenwa.
Zithini iindlela zokunyanga oku? Ngaba kunokunyangwa ngokupheleleyo?
Okokuqala, iindaba ezimnandi. Okwangoku akukho nyango lwesi sifo. Kodwa ungakhathazeki. Kukho unyango olusebenzayo kakhulu lokucothisa ukuqhubela phambili kwesi sifo, ukulawula iimpawu, kunye nokuthintela iingxaki.
Unyango lufuneka kuphela kwabo baneempawu, okanye abo isifo sabo sichaphazele iindawo ezibalulekileyo ezifana nentloko kunye nomqolo.
Amayeza
Udidi oluphambili lwamayeza asetyenziselwa le njongo yi- bisphosphonates . La mayeza alawula inkqubo yokuqhekeka kwamathambo ngokukhawuleza.
- Okwangoku lelona yeza lisebenzayo nelisetyenziswa kakhulu kolu didi.I-Zoledronate . Le yinaliti encinci (`infusion`) efakwa emthanjeni. Ngokufakwa kanye kweli yeza, esi sifo sinokulawulwa iminyaka.
- Kodwa khumbula, la mayeza ayayithintela kuphela into yokuba isifo singasasazeki ngakumbi, kodwa awanakukwazi ukulungisa ukukhubazeka kwamathambo okusele kwenzeke.
Utyando
Utyando luyadingeka xa kukho iingxaki ezibangelwa sesi sifo. Umzekelo:
- Ukuba kukho ukwaphuka, yibeke.
- Ukuba ilungu litshabalaliswe ngokupheleleyo sisifo, yenza utyando lokutshintsha ilungu ledolo okanye lesinqe.
- Ukulungiswa kwamathambo angalungi kakuhle.
- Ukuba kukho uxinzelelo lwemithambo-luvo, yehlisa olo xinzelelo.
Okukhona esi sifo siqatshelwa kwaye sinyangwa ngokukhawuleza, kokukhona iingxaki ezifana nokuqhekeka kwamathambo kunye ne-arthritis zinokuthintelwa ngokukhawuleza. Ke ngoko, kubaluleke kakhulu ukuqaphela iimpawu.
Umyalezo Wokuya Ekhaya
- Isifo sikaPaget seThambo asingomhlaza, kodwa sisifo esingapheliyo esenza amathambo abe buthathaka.
- Abantu abaninzi abanazo iimpawu. Iimpawu eziphambili zisenokuba ziintlungu zamathambo, ukukhubazeka, kunye nokuqhekeka kwamathambo ngokulula.
- Esi sifo sinokuchongwa ngokulula ngokusebenzisa amanqanaba aphezulu e-alkaline phosphatase egazini nakwiimvavanyo ze-X-ray .
- Nangona esi sifo singenakunyangwa ngokupheleleyo, amayeza anjenge -bisphosphonates angasetyenziswa ukulawula esi sifo ngempumelelo nokuthintela iingxaki.
- Ukuba uneminyaka engaphezu kwama-50 ubudala, unembali yosapho lwakho yesi sifo, okanye unentlungu engaqhelekanga nengapheliyo emathanjeni, musa ukuyityeshela kwaye ngokuqinisekileyo bonana nogqirha wakho ukuze akunike ingcebiso.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho