Ingaba inani leeseli zakho ezibomvu zegazi liphezulu ngendlela eyingozi? Masithethe ngePolycythemia Vera (PV)!

Ngaba uhlala uziva udiniwe, ngamanye amaxesha uziva urhawuzelelwa, okanye uva nje ingxolo ezindlebeni zakho? Nangona ezi zinto zinokubonakala ngathi zizinto eziqhelekileyo, ngamanye amaxesha kunokubakho esinye isizathu sazo. Ngoko ke, isifo esiza kuthetha ngaso namhlanje yiPolycythemia Vera (PV) , imeko ebangelwa kukuveliswa kakhulu kweeseli ezibomvu zegazi emizimbeni yethu. Nangona eli ligama elide, masiliqonde ngokulula.

Yintoni iPolycythemia Vera (PV)? Ngamafutshane...

Ngamafutshane, iPolycythemia Vera (PV) yimeko apho umzimba wakho, ingakumbi umongo wakho wethambo (esiwubiza ngokuba yi-"Bone Marrow"), uvelisa iiseli ezibomvu zegazi ezingaphezulu kunokuba kufanele . Njengemigxobhozo yezithuthi, xa kukho iimoto ezininzi endleleni, ukuhamba kwegazi kuyavaleka. Oku kubangela ukuba igazi lijiye kwaye lihambe kancinci. Oku kwandisa umngcipheko wokuqhekeka kwegazi. Oku kunokukhokelela kwiimeko ezinzulu ezifana nokuhlaselwa yintliziyo kunye nokubetha .

Akupheleli nje apho, ngamanye amaxesha iimpawu ezifana nolusu olurhawuzelelayo, ukukhala ezindlebeni (`(Tinnitus)`), iintlungu zesisu, ukopha empumlweni, kunye nokungaboni kakuhle nazo zinokubakho.

I-Polycythemia Vera (PV) yimeko engapheliyo engenakunyangeka ngokupheleleyo. Kodwa ungakhathazeki. Ngonyango olufanelekileyo, ungazilawula iimpawu kwaye unciphise umngcipheko weziphumo ebezingalindelekanga. Abanye abantu bayibiza ngokuba yi-'primary polycythemia', 'polycythemia rubra vera', 'erythema' kunye 'nesifo se-Osler-Vaquez'.

Ngaba iPolycythemia Vera (PV) ngumhlaza?

Ewe, olu luhlobo lomhlaza ngokwenene. Kodwa alubi nzulu okanye lusasazeka ngokukhawuleza njengoko sinokucinga xa sisiva igama elithi umhlaza. Lo ngumhlaza wegazi okwiqela elibizwa ngokuba yi -`myeloproliferative neoplasm (MPN) . I-`MPN` ibhekisa kwiqela lezifo ezibangela ukuveliswa ngokugqithisileyo kweentlobo ezahlukeneyo zeeseli zegazi.

Eyona nto ibangela iPolycythemia Vera (PV) lutshintsho (uguquko) kwijini emzimbeni wethu. Oku akusiyonto esizalwa nayo, kodwa yinto eyenzeka ebomini bethu ngesizathu esingaziwayo. Esi sifo sikhula kancinci kakhulu. Sihlala sichongwa emva kweminyaka engama-60. Lo mhlaza awufane ubangele ukufa ngokuthe ngqo. Umngcipheko ophambili uvela kwiingxaki ezibangelwa kukuqhekeka kwegazi. Kwakhona, kwipesenti encinci kakhulu, unokujika ube zezinye iintlobo zomhlaza wegazi ezinzulu.

Ngubani ochaphazeleka kakhulu yile meko?

I-Polycythemia Vera (PV) sisifo esingaqhelekanga kakhulu. Kwilizwe elifana ne-United States, sivela kubantu abamalunga nama-50 kwi-100,000. Sixhaphake kakhulu kubantu abangaphezu kweminyaka engama-60 ubudala.

Esi sifo siyichaphazela njani imizimba yethu?

Njengoko besitshilo ngaphambili, iPolycythemia Vera (PV) ibangela ukuba umzimba uvelise iiseli ezibomvu ezininzi kakhulu. Oku kugqithisela kweeseli kwandisa umngcipheko wokopha, ukukrweleka, kunye nokuqhekeka kwegazi. Ngenxa yokuba igazi liqina kwaye lihamba kancinci, izicubu kunye namalungu omzimba wethu awafumani ioksijini ayidingayo.

Oku kubeka umsebenzi omninzi kwi-spleen yomzimba wethu. Omnye wemisebenzi ephambili ye-spleen kukucoca igazi nokususa iiseli zegazi ezindala. Xa iiseli ezibomvu zegazi zisanda, i-spleen nayo iyasebenza kakhulu, nto leyo enokubangela ukudumba kunye nentlungu. Oku kubizwa ngokuba yi-`(Splenomegaly)`. Ekuhambeni kwexesha, le meko inokubangela iimpawu ezahlukeneyo ezingathandekiyo. Kwakhona, i-PV inokubangela ezinye iimeko zesibini.

Zithini iingozi kunye neengxaki zePolycythemia Vera (PV)?

Nangona i-PV sisifo esiqhubekayo, kukho umngcipheko wokuqhekeka kwegazi ngequbuliso ngenxa yokuveliswa kakhulu kweeseli zegazi. Ekuhambeni kwexesha, i-PV inokubangela nezinye iimeko zesibini. Amaxesha amaninzi, inokujika ibe ngumhlaza onzima.

Amahlwili egazi

Le yeyona ngozi iphambili neyona ikhawulezileyo ye-PV. Ukuba ihlwili legazi lenzeka lize liye entliziyweni okanye ebuchotsheni, lingabangela ukuhlaselwa yintliziyo okanye isifo sohlangothi . Ukuba lihamba liye emiphungeni (i-Pulmonary Embolism - PE), linokubangela uxinzelelo lwegazi oluphezulu emiphungeni (i-pulmonary hypertension) kunye nokusilela kwentliziyo. Ukuba ihlwili legazi libambeka emthanjeni (i-Venous Thromboembolism - VTE), linokubangela ukufa kwezicubu okanye ukungasebenzi kakuhle kwemithambo yegazi. Ukuba ihlwili legazi libambeka emthanjeni wegazi oyintloko oya esibindini (i-hepatic vein thrombosis), linokubangela ihlwili legazi esibindini (i-Budd-Chiari syndrome), i-jaundice kunye nokusilela kwesibindi.

Iimeko zesibini

Xa iiseli ezibomvu zegazi ziveliswa ngokugqithisileyo kwaye ziqhekeka, inqanaba le-'uric acid' emzimbeni liyakhula. Oku kunokubangela iingxaki ezininzi:

• Amatye ezintso: Xa i-uric acid ifakwa kwizintso.
• I-Gout: Imeko ebuhlungu ye-arthritis eyenzeka xa i-uric acid iqokelelana emalungeni.
• Izilonda zesisu: Iiseli ezibomvu zegazi ezingaphezulu zikwanyusa ubungakanani be-asidi yesisu. Iiseli ezibomvu zegazi ezingaphezulu zibangela ukuba umzimba ukhuphe ikhemikhali ebizwa ngokuba yi-histamine, nto leyo ebangela ukuba isisu sivelise i-asidi engakumbi yokulwa nosulelo. Abantu abane-PV banamathuba aphindwe kane okuba nezilonda zesisu (isifo sesilonda se-peptic).

Ukujika kwiLeukemia

I-Polycythemia Vera ngumhlaza womongo wamathambo, kodwa ayisiyonto ibeka ubomi esichengeni. Ngonyango olufanelekileyo, inokulawulwa kakuhle iminyaka. Nangona kunjalo, kwabanye abantu, i-PV inokwenza, nangona kunqabile,Ingaguquka ibe ngumhlaza wegazi onzima njenge-'Acute Leukemia'.

Amanqanaba eSifo sePolycythemia Vera (PV)

Isifo se-PV siqhubeka ngolu hlobo lulandelayo:

• Inqanaba lokuqala (`I-PV yasekuqaleni`): Ngeli nqanaba, kukho iimpawu ezimbalwa okanye akukho kwaphela.
• Ukuqhubela phambili kwe-PV: Njengoko i-PV isiba mandundu, unokuqala ukufumana iimpawu ezingathandekiyo, okanye ezinye iimeko zinokuvela.
• Isigaba sokuchitha: Oku kubizwa ngokuba “sisigaba sokuchitha.” Kule ndawo, iiseli zegazi ezingaqhelekanga ezibangela esi sifo ziyanda zingalawuleki kwaye zivale ngokupheleleyo umongo wethambo, nto leyo eyenza iiseli zegazi. Xa ezi seli zingaqhelekanga zisifa, kuvela izicubu zesilonda endaweni yazo. Xa uninzi lomongo wethambo luzaliswe yile zicubu zesilonda, awukwazi ukwenza iiseli zegazi eziphilileyo. Okumangalisayo kukuba, oku kubangela i-anemia - ukungabikho kweeseli zegazi ezibomvu eziphilileyo. Kwakhona kwandisa umngcipheko wokopha.

Ezinye izifo zegazi ezinokwenzeka emva kwe-PV

Xa i-PV iba mandundu, inokukhokelela kwezinye izifo zegazi.

• I-Myelofibrosis (MF): Akukho mahluko mkhulu phakathi kwe-"spent phase" ye-PV kunye ne-"Myelofibrosis (MF)" , olunye uhlobo lomhlaza wegazi. Abanye oogqirha bacinga ukuba ziyafana. I-"Myelofibrosis" kuxa iiseli ezingaqhelekanga zenza izicubu ezikrwelekileyo kumongo wethambo zize ziwuzalise. Ezi seli ezingaqhelekanga zinokusasazeka ngaphandle komongo wethambo ziye kwezinye iindawo zomzimba. I-"MF" ikwayi-"myeloproliferative disorder." Malunga ne-10% yezigulana ze-"MF" ziba ne-"Acute Myeloid Leukemia."
• I-Myelodysplastic Syndrome (MDS): Amaxesha amaninzi, i-PV inokukhula ibe yimeko ebizwa ngokuba yi -Myelodysplastic Syndrome (MDS) . Le yimeko apho iiseli zegazi zingakhuli kakuhle, zikhule ngendlela engaqhelekanga, kwaye zife ngokukhawuleza. Umzimba awukwazi ukwenza iiseli eziphilileyo nezivuthiweyo, nto leyo ebangela ukwehla kwenani leentlobo ezahlukeneyo zeeseli zegazi. I-MDS inzima kakhulu kune-PV okanye i-MF, kwaye inomngcipheko we-30% wokufumana i-Acute Myeloid Leukemia (AML).
• I-Acute Myeloid Leukemia (AML): Malunga ne-3% yabantu abanePolycythemia Vera bafumana i-Acute Myeloid Leukemia (AML) kwiminyaka eli-10 emva kokufunyaniswa kwesifo. I-AML ngumhlaza wegazi onzima oqala kumongo wethambo kwaye unokusasaza ngokukhawuleza uye egazini uze uye kwezinye iindawo zomzimba. Ifuna unyango olukhawulezileyo, kodwa amathuba okusinda aphezulu.

Zithini iimpawu zePolycythemia Vera (PV)?

Iimpawu zihlala zibonakala kancinci kakhulu, kwaye ngamanye amaxesha zisenokungabikho kwaphela iimpawu. Okokuqala, iimpawu ezingacacanga eziqhelekileyo kwizifo ezininzi:

• Intloko ebuhlungu.
• Isiyezi.
• Ukudinwa.
• Igazi elonyukayo.
• Umbono ofipheleyo okanye umbono ophindwe kabini.
• Ukuva isandi ezindlebeni (`(Tinnitus)`).

Ngokuhamba kwexesha, iimpawu ezithile zinokuvela:

• Ukubila, ingakumbi ebusuku.
• Ubunzima bokuphefumla, ingakumbi xa ulele phantsi.
• Ulusu olurhawuzelelayo, ingakumbi emva kokuhlamba ngamanzi ashushu. (Olu luphawu oluthile lwe-PV)
• Ububomvu, ubushushu, ukungaziva mnandi, okanye ukutsha kwamalungu omzimba.
• Ukopha kakhulu okanye ukukrweleka.
• Ukopha okuphuma empumlweni nasezintsinini.
• Ukuba mncane ngaphandle kwesizathu.

Ukuba i-PV iba mandundu ize iqhubekele kwiimeko zesibini, iimpawu ezinxulumene noko zinokuvela. Umzekelo:

Iimpawu ze-Splenomegaly:

• Intlungu efana nento ethile inamathele kwinxalenye ephezulu yasekhohlo yesisu.
• Amava okugcwalisa isisu.
• Nokuba nditye kancinci, ndiziva ndihluthi.

Iimpawu zezilonda zesisu (`Isifo sesilonda sePeptic`):

• Intlungu ehambisana nentlungu yesisu.
• Isitshiso sentliziyo.
• Ukubuyela kwe-asidi.

Iimpawu zeGout:

• Ukudumba okubuhlungu kwamalungu.
• Ukuqina kwamalungu.
• Ukudumba kobhontsi omkhulu.

Iimpawu zamatye ezintso:

• Intlungu esiswini esisezantsi okanye emqolombeni.
• Intlungu xa uchama.
• Ukufuna ukuchama rhoqo.

Iimpawu zesifo sikaBudd-Chiari:

• Ukudumba kwesibindi, iintlungu kwicala eliphezulu lasekunene lesisu, kunye nokudumba.
• Ukutyheli kwamehlo nolusu (i-jaundice).
• I-Ascites kunye ne-Edema.

Iimpawu zeDeep Vein Thrombosis (DVT):

• Ukudumba engalweni okanye emlenzeni kunye nentlungu xa uchukunyiswa.
• Kukho ubomvu okanye ubushushu kuloo ndawo.
• Ukubonakala kwemithambo yegazi evuvukileyo phezu kolusu.

Iimpawu zokuqhekeka kwegazi emiphungeni (Pulmonary Embolism - PE):

• Intlungu yesifuba ngequbuliso.
• Ukuqhawukelwa ngumphefumlo.
• Isantya sentliziyo siyanda.

Iimpawu ze-Anemia (kwinqanaba lokugqibela lesifo se-PV):

• Isiyezi (vertigo).
• Ulusu oluphaphathekileyo.
• Ukudinwa.

Yintoni ebangela iPolycythemia Vera (PV)?

I-Polycythemia Vera (PV) iqala kwinxalenye ethambileyo nethambileyo yamathambo ethu ebizwa ngokuba yi-bone marrow. Kulapho kwenziwa khona iiseli ezintsha zegazi. I-PV iqala ngokuguqulwa kwe-gene enye kwiseli enye ye-stem kwi-bone marrow. Ngaphezulu kwe-90% yexesha, olu tshintsho lukwi-gene ebizwa ngokuba yi-JAK2.

Le gene iguqukileyo ixelela i-stem cell ukuba iqhubeke nokuzala. Yonke iseli eveliswayo iyaqhubeka nokuzala. Ekugqibeleni, ezi seli zingaqhelekanga zizalisa umongo wethambo, zingashiyi ndawo yeeseli eziqhelekileyo.

Kwiimeko ezininzi, olu tshintsho lwe-'JAK2' aluyonto esiyizuz’ ilifa. Luyinto eyenzeka ebomini bethu, ngezizathu ezingaziwayo. Nangona kunjalo, kunqabile kakhulu, kubekho iingxelo zamalungu amaninzi osapho afumana i-PV.

Ifunyanwa njani iPolycythemia Vera (PV)?

I-World Health Organisation (WHO) iphakamise iindlela ezintathu eziphambili zokuxilonga i-Polycythemia Vera (PV). Ugqirha kufuneka aqinisekise zonke ezi ndlela zintathu.

Ikhrayitheriya 1: Uvavanyo lwegazi olubonisa inani eliphezulu leeseli ezibomvu zegazi:

Iiseli ezibomvu zegazi zinokulinganiswa:

• Amanqanaba aphezulu e-hemoglobin (iproteni efumaneka kwiiseli ezibomvu zegazi).
• Inqanaba eliphezulu le-hematocrit (ipesenti yeeseli ezibomvu zegazi egazini).
• Umthamo wegazi ophezulu (ubunzima beeseli ezibomvu).

Ikhrayitheriya yesi-2: Uvavanyo lwe-bone marrow biopsy olubonisa enye yezi zilandelayo:

• Iiseli zegazi ezininzi kakhulu kumongo wethambo, okanye
• Ukubakho ngokugqithisileyo kwee-megakaryocytes ezivuthiweyo (iiseli ezenza iiplatelets zegazi).

Ikhrayitheriya 3: Ikhrayitheriya yesithathu inokufezekiswa ngokubonisa nayiphi na kwezi zimbini:

• Ukuqinisekiswa kobukho bokuguqulwa kwezakhi zofuzo ze-JAK2 ngovavanyo lweemolekyuli, okanye
• Uvavanyo lwegazi luqinisekisa ukuba inqanaba le -`erythropoietin' (ihomoni evuselela ukuveliswa kweeseli ezibomvu zegazi zizintso) egazini liphantsi kakhulu.

"Ugqirha uza kuzijonga zonke ezi zinto ukuze akuxelele ukuba unayo na iPolycythemia Vera okanye akunjalo. Ngoko ke ukuba uneempawu, kungcono ukubona ugqirha ukuze ufumane ingcebiso."

Inyangwa njani iPolycythemia Vera (PV)?

Kwinqanaba lokuqala le-PV, unyango lulula kakhulu. Unyango oluqhelekileyo luquka:

I-Phlebotomy (ukukhupha igazi)

Olu lolona nyango luphambili noluqhelekileyo lwe-PV. Lwenziwa ngendlela efanayo naleyo ubuya kunikela ngayo ngegazi. Umboneleli wezempilo ufaka inaliti emthanjeni osengalweni yakho aze asuse igazi elincinci (ngesiqhelo malunga nepayinti, kodwa ubungakanani bungahluka ngokuxhomekeke kwimeko yakho). Oku kunciphisa umthamo wegazi lakho lilonke kunye nenani leeseli zegazi ezongezelelweyo.

I-aspirin yedosi ephantsi

Eli liyeza onokulithenga kwikhemesti. Lidla ngokunikwa umlinganiselo wokunciphisa umngcipheko wokuqhekeka kwegazi. Xa lithathwa ngedosi ephantsi kanye ngemini, i-aspirin ithintela iiplatelets zegazi ukuba zinganamatheli. Ikwanceda ekunciphiseni iimpawu ezifana nokudumba kwamalungu. Nangona kunjalo, linzima kancinci esiswini kwaye lonyusa ukopha. Ngoko ke oku akulunganga ukuba unezilonda zesisu.

Ukuba iimpawu zakho zinzima, okanye ukuba unembali yokuqhekeka kwegazi ngaphambili (thrombosis), ungabekwa kwiqela elinomngcipheko ophezulu kwaye ezinye iindlela zonyango zingacetyiswa. Ezinye zezi ziquka:

Unyango lokunciphisa ukurhawuzelela:

Xa i-PV iba mandundu, ugqirha angakunika amayeza afana nala ukunyanga ukurhawuzelelwa:

• Ii-Antihistamines: La ngamayeza aqhelekileyo anikwayo kubantu abane-allergies.
• I-Phototherapy: Unyango oludibanisa ukukhanya kwe-ultraviolet (UVA) kunye nekhemikhali ebizwa ngokuba yi-psoralen (ikhompawundi yendalo evuselela ulusu kunyango lokukhanya).
• Ii-SSRI (Selective Serotonin Reuptake Inhibitors): Ezi luhlobo lwamayeza adla ngokunikwa uxinezeleko. Nangona kunjalo, xa zinikwa ngeedosi eziphantsi kakhulu, zifunyenwe zisebenza kakuhle kwiimpawu zomzimba ezihlala zihleli ezifana nokurhawuzelelwa.

Amayeza anciphisa inani leeseli ezibomvu zegazi:

Ezi zingasetyenziswa zodwa okanye xa zidibene. Imizekelo:

• `I-Hydroxyurea`
• `I-Interferon alfa`
• `Ruxolitinib`
• `Busulfan`

Uvavanyo lwezonyango

Oku kunika abantu ithuba lokuzama unyango lwamva nje kunye negalelo kuphando lwezonyango. Amanye amayeza akwisigaba sophando okwangoku ngala:

• `I-Peginterferon alfa-2a`
• `I-Givinostat`
• `Idasanutlin`

Ukufakelwa komongo wethambo

Kwezinye iimeko, kunokucetyiswa ukuba utyando lwethambo lufakwe kwithambo. Ugqirha uya kwenza esi sigqibo ngokusekelwe kwizinto ezahlukeneyo, njengobunzima besifo sakho kunye nokukwazi komzimba wakho ukuphiliswa.

Inkathalo exhasayo

Ukuba i-PV yakho iyaqhubeka nokuba mandundu nangona unyango luqhubeka, ugqirha wakho uya kugxila ekulawuleni iimpawu zakho. Kwinqanaba lokugqibela le-PV, unokufumana i-anemia kunye nokwanda kwepleen. Unokufumana unyango olufana nolu:

• Izibulali-ntlungu.
• Utofelo-gazi.
• Unyango lwemitha oluphantsi kwi-spleen.

Ingakanani iminyaka yobomi bomntu onePolycythemia Vera (PV)?

Izifundo zakutshanje zibonisa ukuba umyinge wobomi emva kokufunyaniswa unePolycythemia Vera (PV) umalunga neminyaka engama-20. Umyinge wobudala bokufa umalunga neminyaka engama-77. Unobangela ophambili wokufa ziingxaki ezibangelwa kukuqhekeka kwegazi (malunga nama-33%). Unobangela wesibini ophambili ngumhlaza (malunga ne-15%).

"Musa ukoyika ezi zibalo. Ezi zizinto eziqhelekileyo. Ukuba ufumana unyango olufanelekileyo kwaye wenze utshintsho kwindlela ophila ngayo, ungahlala usempilweni ixesha elide."

Ndingazinyamekela njani kwaye ndilawule iimpawu zam?

Ukuba uphila nePolycythemia Vera (PV), kubalulekile ukuhlala unxibelelana nogqirha wakho rhoqo. Oku kuya kunceda ugqirha wakho ukuba ajonge indlela imeko yakho eqhubeka ngayo. Ungamxelela ugqirha wakho indlela osabela ngayo kunyango kunye nokuba kukho naziphi na iziphumo ebezingalindelekanga. Ungaphila ixesha elide ngaphandle kweempawu ezinzulu.

Ukongeza kwiimvavanyo kunye nonyango oluqhelekileyo, ugqirha wakho uya kucebisa utshintsho olulula lwendlela yokuphila olunokunceda ukuthintela ukuqhekeka kwegazi kunye nezinye iingxaki. Umzekelo:

• Ukuzilolonga. Nokuba ukwenza umthambo omncinci kunokunceda ukuphucula ukujikeleza kwegazi.
• Kuphephe ukutshaya. Ukutshaya kuyayinciphisa imithambo yegazi yakho.
• Ziphephe iindawo ezineoksijini ephantsi. Ukuphakama okuphezulu kunokubangela amanqanaba eoksijini ephantsi egazini.
• Lawula uxinzelelo lwakho lwegazi. Ukugcina ubunzima obusempilweni kuya kunceda koku.

Nangona iPolycythemia Vera (PV) luhlobo lomhlaza, abantu abaninzi baphila kakuhle amashumi eminyaka emva kokuba befunyaniswe benale ntsholongwane. Lo mhlaza uvela kuba iiseli ziveliswa zingalawuleki. Nangona kunjalo, kuthatha ixesha elide ukuba imveliso engalawulekiyo yeeseli ezibomvu zegazi iqale ukukuchaphazela. Nokuba wenza njalo, ungayilawula imeko ixesha elide ngokususa inxalenye yegazi lakho eligqithisileyo.

Eyona ngozi inkulu evela kwiPolycythemia Vera (PV) ayiveli kumhlaza ngokwawo, kodwa kumngcipheko wokuqhekeka kwegazi. Ukuba uphila nePV, ​​qiniseka ukuba ubona ugqirha wakho rhoqo. Kwaye ungalibali ukuzinyamekela "ngezinto ezincinci" - oko kukuthi, imikhwa yokuphila enempilo. Ezi zinceda ukugcina impilo jikelele yenkqubo yakho yentliziyo, enokuba ibaluleke ngaphezu kwalo naluphi na unyango lwePolycythemia Vera.

Sithini isigidimi esifuna ukusithatha sibuyele ekhaya kweli bali?

Kulungile, ngoko ke sithethe kakhulu ngePolycythemia Vera (PV). Nazi ezinye zezinto ezibalulekileyo ekufuneka uzikhumbule:

• I-PV sisifo segazi apho umzimba uvelisa iiseli ezibomvu zegazi ezininzi kakhulu kwaye zikhula ngendlela engaqhelekanga. Sikwiqela leemhlaza ezibizwa ngokuba yi-`myeloproliferative neoplasm (MPN)`.
• Ingozi ephambili ivela ekuqineni kwegazi kunye nokujiya kwegazi, okunokukhokelela kwiimeko ezinzulu ezifana nokuhlaselwa yintliziyo kunye nokubetha kwentliziyo.
• Iimpawu zingabandakanya ulusu olurhawuzelelayo (ingakumbi emva kokuhlamba), ukuziva udiniwe, intloko ebuhlungu, kunye nesiyezi.
• Nangona ingenakunyangwa ngokupheleleyo, inokulawulwa kakuhle ngonyango olufanelekileyo, utshintsho kwindlela yokuphila, kunye namayeza. I-Phlebotomy (ukukhupha igazi) kunye ne-aspirin yedosi ephantsi zezona ndlela ziphambili zonyango.
• Utshintsho lwe-gene lwe-`JAK2` ludla ngokuba yimbangela yoku.
• Ukuba unayo nayiphi na kwezi mpawu, qiniseka ukuba ubona ugqirha ukuze akunike iingcebiso. Ukuchongwa kwangoko kwandisa amathuba akho okuphepha iingxaki nokuphila ubomi obusempilweni.

Musa ukoyika, kodwa ungakuthathi lula. Nyamekela impilo yakho. Thetha nogqirha wakho rhoqo, ufumane uvavanyo olufunekayo kunye nonyango ngexesha. Emva koko ungahlala usempilweni nangona unale meko!

I- Polycythemia Vera, Iiseli zegazi ezibomvu, Amahlwili egazi, i-MPN, i-JAK2, i-Phlebotomy, umhlaza