Ngaba umjikelo wakho wokuya exesheni ngequbuliso uye waba yinto engahambelaniyo? Okanye ngaba kukho ukukhupha okumhlophe okufana nobisi emabeleni akho, nokuba awukhulelwe okanye awuncancisi? Ukuba uyindoda, ngaba ukhe wahlangabezana nokuncipha komdla wesondo okanye ezinye iimeko ezinengxaki? Isizathu sezi zinto sisenokuba yinto ongazange uyicinge. Namhlanje sithetha ngemeko enjalo, oko kukuthi, isifo esibizwa ngokuba yiProlactinoma.
Ngamafutshane, yintoni iProlactinoma?
I-Prolactinoma sisimila esikhula kwi-gland encinci ekufutshane kakhulu nengqondo yethu, ezantsi kwengqondo, ebizwa ngokuba yi-pituitary gland. Ngoku, musani ukoyika xa sithi "i-tumor." Esi sisimila esingengomhlaza (esingenobungozi). Oko kuthetha ukuba asisimila esisongela ubomi esisasazeka emzimbeni wonke njengomhlaza. Olu lolona hlobo luqhelekileyo lwesimila esikhula kwi-pituitary gland.
Le thumba ibangela ukuba umzimba wethu uvelise ihomoni ebizwa ngokuba yi-prolactin ngaphezu kokuba kufanele. Ngokwesiqhelo, le homoni ye-prolactin ibaluleke kakhulu ekuphuhlisweni kwamabele kwabasetyhini kunye nokuveliswa kobisi lokuncancisa (ukuncancisa). Kodwa xa le homoni isanda, kuvela imeko ebizwa ngokuba yi-hyperprolactinemia, inokubangela iingxaki ezahlukeneyo kubasetyhini nakumadoda.
Ukukhankanywa kwethumba elikufutshane nobuchopho kunokoyikisa. Kodwa khumbula, i-prolactinoma ayisongeli ubomi. Nangona kunjalo, ngenxa yeengxaki zempilo enokubangelwa yiyo, kubalulekile ukufuna uncedo lwezonyango ukuba kuvela iimpawu.
Ngaba kukho iintlobo zeprolactinoma?
Ewe, la mandongomane ahlulwe abe ziintlobo ezimbini eziphambili ngokobukhulu bawo. Ukuze uqonde oku, jonga itheyibhile engezantsi.
| Uhlobo lwethumba | Ubungakanani | Eyona ibonwa rhoqo |
|---|---|---|
| Ii-Microprolactinomas | Ezi zincinci kakhulu, zingaphantsi kwesentimitha enye ngobukhulu. | Ixhaphake kakhulu kubasetyhini. Ama-90% abasetyhini abane-prolactinoma banolu hlobo luncinci lwethumba. |
| IiMacroprolactinomas | Ezi zinkulu kune-1 centimeter. | Ixhaphake kakhulu kumadoda. Malunga nama-60% amadoda ane-prolactinoma anolu hlobo lwethumba elikhulu. |
Zithini iimpawu zoku?
Iimpawu zixhomekeke kubungakanani be-prolactin hormone eveliswayo kunye nobukhulu bethumba. Makhe sibone ukuba zeziphi ezi mpawu.
| Uhlobo oluneempawu | Inkcazo |
|---|---|
| Iimpawu eziqhelekileyo ezibangelwa yi-hormone ephezulu yeprolactin | |
| Iimpawu kubafazi |
|
| Iimpawu kumadoda | |
| Iimpawu eziqhelekileyo kumaqela omabini | |
| Iimpawu ezibangelwa sisimila esikhulu (iMacroprolactinoma) | |
| Iimpawu ezinxulumene nentloko kunye nokubona |
|
Abafazi banamathuba amaninzi okuyibona le meko kwangethuba ngenxa yeempawu ezifana notshintsho kumjikelo wabo wokuya exesheni okanye ukuphuma kwesisu emabeleni. Nangona kunjalo, abantu abathatha iipilisi zokulawula ukuzala okanye ezinye iindlela zonyango lweehomoni basenokungaziboni ezi mpawu. Kwakhona, iimpawu zinokulibaziseka kubafazi nakumadoda asele eqhelile ukuya exesheni, nto leyo enokulibazisa ukuxilongwa.
Yintoni isizathu soku?
Enyanisweni, abaphandi abakafumani sizathu sithile seProlactinoma. Uninzi lwexesha, yenzeka ngamaxesha athile, ngaphandle kwesizathu esithile. Nangona kunjalo, ezinye iimeko zemfuza zinokunyusa umngcipheko.
- ``I-Multiple endocrine neoplasia (MEN) uhlobo 1''
- `Uhlobo lwamadoda 4`
- ``Ii-Familial isolated pituitary adenomas (FIPA)''
Uyifumana njani le nto, Gqirha?
Ugqirha wakho uza kuqala ajonge iimpawu zakho kunye nembali yakho yezonyango. Emva koko, uza kwenza uvavanyo lomzimba. Emva koko angacebisa iimvavanyo ezininzi ukuqinisekisa ukuxilongwa.
- Uvavanyo lwegazi lweprolactin: Olu lolona vavanyo lusisiseko. Ukuba olu vavanyo luqinisekisa ukuba amanqanaba akho eprolactin aphezulu kakhulu kunesiqhelo, uya kuthunyelwa kwiimvavanyo ezongezelelweyo ukuze kuhlolwe ithumba.
- I-MRI okanye i-CT scan: Ezi scan zinokubonisa ngqo ukuba kukho ithumba le-pituitary na, kwaye ukuba likho, likhulu kangakanani. Oogqirha badla ngokucebisa ukuba kwenziwe i-MRI scan.
- Uvavanyo lwegazi lwenqanaba le-Testosterone: Ukuba uyindoda, ugqirha wakho unokucebisa ukuba uvavanye amanqanaba e-hormone yakho ye-testosterone.
Ukuba isifo siqinisekisiwe, kunokucetyiswa ukuba ujonge amanqanaba amanye amahomoni kwi-pituitary gland kwaye uhlolwe amehlo yingcali yamehlo ukuze ubone ukuba umbono wakho uchaphazelekile na ukuba unethumba elikhulu (macroprolactinoma).
Zithini iindlela zonyango zoku?
Iindaba ezimnandi zezokuba kukho unyango olusebenzayo kakhulu koku. Kwiimeko ezininzi, le meko inokulawulwa ngamayeza.
Amayeza (amayeza)
Oogqirha badla ngokunika amayeza abizwa ngokuba yi-dopamine agonists. La mayeza anokunciphisa i-prolactinoma aze abuyisele amanqanaba e-prolactin kwisiqhelo.
- I-Cabergoline kunye neBromocriptine: La ngamayeza amabini aphambili asetyenziswayo. Kula mayeza, i-cabergoline lolona khetho luphambili koogqirha kuba isebenza ngakumbi kwaye ineziphumo ebezingalindelekanga ezimbalwa.
- Iziphumo ebezingalindelekanga: La mayeza anokubangela iziphumo ebezingalindelekanga ezincinci ezifana nokucaphuka, ukuhlanza, kunye nesiyezi.
- Ubude bonyango: Ukuze uthintele ukuba ithumba lingabuyi, kuya kufuneka ulithathe rhoqo eli yeza ubuncinane iminyaka emibini . Emva kweminyaka emibini, ukuba amanqanaba akho e-prolactin abuyele esiqhelweni kwaye ithumba alisabonakali kwiiskeni, ugqirha wakho uya kunciphisa kancinci umthamo weyeza aze ekugqibeleni aliyeke.
Utyando
Utyando alufuneki rhoqo. Oku kwenzeka kwiimeko ezifana nezi:
- Ukuba iyeza linemiphumo emibi kakhulu.
- Ukuba ithumba alinciphi ngamayeza.
- Ukuba eli yeza lidibana namanye amayeza owasebenzisayo.
- Ukuba unethumba elikhulu kwaye kufuneka lisuswe ngaphambi kokuba uzame ukukhulelwa.
Kukho iintlobo ezimbini zotyando.
1. Utyando lwe-transsphenoidal: Olu lolona tyando luqhelekileyo. Apha, ithumba lisuswa ngomngxuma omncinci ngaphakathi kwempumlo okanye phantsi komlomo ongaphezulu.
2. Utyando lwe-transcranial: Ukuba ithumba likhulu kakhulu, ithumba lisuswa ngomngxuma omncinci ekhakhayini.
Unyango ngemitha
Unyango ngemitha lukhetho lwesithathu xa umhlaza ungaphenduli kumayeza okanye kutyando. Olu lunyango olungaqhelekanga kakhulu.
Iyintoni imbonakalo yesi sifo?
Ithemba le-prolactinoma lihle kakhulu. Ngonyango lwezonyango, abantu aba-4 kwaba-5 abaneethumba ezincinci banokuphucula amanqanaba abo e-prolactin kwaye ithumba linokuncipha.
Utyando ludla ngokuphumelela. Xa lwenziwa ngugqirha onamava, amanqanaba e-prolactin anokubuyiselwa kwisiqhelo kubantu abamalunga nama-90% abaneethumba ezincinci kunye nama-50% abantu abaneethumba ezinkulu.
Umyalezo Wokuya Ekhaya
- I-Prolactinoma sisimila esingengomhlaza (esingenobungozi), ngoko ke musa ukuyoyika ngokungeyomfuneko.
- Ukuba uneempawu ezifana nokungaqheleki kwemijikelo yokuya exesheni, ukuphuma kolwelo olufana nobisi emabeleni, okanye iingxaki zesondo, musa ukuba neentloni ngaloo nto kwaye ubone ugqirha ngokukhawuleza.
- Esi sifo sinokuchongwa lula ngokuhlolwa kwegazi kunye neeskeni ezifana neMRI.
- Amayeza adla ngokuba lolona nyango luphambili, kwaye asebenza kakuhle kakhulu. Utyando alufuneki rhoqo.
- Le yimeko engabulaliyo, enyangekayo nenganyangekayo. Ngoko ke landela imiyalelo kagqirha wakho uze ufumane unyango.
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