Ndiyayiqonda indlela ovakalelwa ngayo luloyiko, ixhala, kunye nokungaqiniseki xa ugqirha wakho ekuxelela okanye umntu omthandayo ukuba unomhlaza. Kwangaxeshanye, xa ugqirha wakho ekuxelela ngonyango olubizwa ngokuba yi-“R-CHOP,” mhlawumbi unemibuzo emininzi efika engqondweni yakho, efana nokuthi, “Yintoni le? Isebenza ntoni?” Ungakhathazeki. Namhlanje, siza kuthetha ngokuba yintoni i-R-CHOP, yintoni eyenzayo, kunye nendlela yokujongana nayo ngendlela elula kakhulu onokuyiqonda.
Kalula nje, yintoni i-R-CHOP?
I-R-CHOP yindibaniselwano yamayeza amahlanu abulala iiseli zomhlaza . Lunyango olusebenzayo kakhulu kuhlobo lomhlaza olubizwa ngokuba yi-non-Hodgkin lymphoma . Unobumba ngamnye egameni ubhekisa kwiyeza elisetyenziswa kolu nyango.
| Ileta | Iyeza kunye nesenzo salo |
|---|---|
| R | I-Rituximab: Olu lunyango olujoliswe kulo. Ngokukodwa, eli yeza linamathela kwiproteni ekhethekileyo kumphezulu weeseli zomhlaza. Oku kuvumela amajoni omzimba wethu ukuba azibone kwaye azitshabalalise ngokulula ezi seli zomhlaza. |
| C | I-Cyclophosphamide: Eli liyeza le-chemotherapy. Amayeza e-chemotherapy asebenza ngokutshabalalisa iiseli ezahlulahlula ngokukhawuleza, ezifana neeseli zomhlaza. |
| H | I-Doxorubicin hydrochloride (Hydroxydaunomycin): Le ikwaliyeza le-chemotherapy. |
| O | I-Vincristine sulfate (i-Oncovin): Eli lelinye iyeza le-chemotherapy. |
| P | I-Prednisone: Olu luhlobo lwe-steroid (i-corticosteroid). Ikwabulala iiseli zomhlaza. Ikwanceda ekunciphiseni ii-allergy ezinokwenzeka ngamanye amayeza e-R-CHOP. |
Njengoko ubona, oku kubandakanya amayeza e-chemotherapy kunye neyeza elijolise kumajoni omzimba (i-Rituximab). Yiyo loo nto oogqirha ngamanye amaxesha bebiza olu nyango ngokuthi "yi-immuno-chemotherapy."
Zeziphi iintlobo zomhlaza ezisetyenziselwa unyango lwe-R-CHOP?
Olu nyango lunikezelwa ikakhulu kuhlobo lomhlaza olubizwa ngokuba yi-non-Hodgkin lymphoma . Lusebenza kakhulu nakwi- lymphoma ye-B-cell esasazeka kakhulu (i-DLBCL) . Ukongeza, i-R-CHOP ikwasetyenziswa kwezi ntlobo zilandelayo zomhlaza :
- I-follicular lymphoma ephucukileyo
- I-Mantle cell lymphoma
- I-Waldenstrom macroglobulinemia
Kwezinye iimeko, ugqirha wakho unokugqiba ekubeni anike i-R-CHOP kunye nonyango lwezinye iintlobo zomhlaza.
Lusebenza njani unyango?
Unyango lwe-R-CHOP lunikwa “ngemijikelo.” Umjikelo ngamnye uhlala iiveki ezintathu (iintsuku ezingama-21). Kukho iinxalenye ezimbini kulo mjikelo:
1. Iintsuku zonyango: Iintsuku onikwa ngazo amayeza.
2. Iintsuku zokuphumla: Iintsuku zokuvumela umzimba wakho ukuba uphilise kwaye uphile ngaphambi komjikelo olandelayo.
Iintsuku zonyango
Eli yeza linokunikwa kangangeentsuku ezintlanu. I-Prednisone (i- steroid ) yipilisi oyiginyayo. Amanye amayeza amane anikwa njengesicombululo setyuwa emthanjeni (i-intravenous infusion - IV). Oku kuya kufuna ukuba uye esibhedlele okanye ekliniki. Apho uya kuhlala esitulweni ngelixa umatshini ufaka eli yeza kancinci emthanjeni emzimbeni wakho. Eli yeza lisenokuba sengalweni yakho, esandleni, okanye esifubeni. Ukuba unyango lunikezelwa ngesifuba, isixhobo esincinci esibizwa ngokuba yi-'port-a-cath' (i-chemo port) sinokufakwa phantsi kolusu.
Ngosuku lokuqala lonyango, uza kunikwa amayeza okuthintela isicaphucaphu. Uza kunikwa namayeza okuthintela i - allergies.Kuqhelekile ukuba nesiyezi kancinci kwaye ufudumale xa unikwa iyeza. Yiyo loo nto eli yeza linikwa ngononophelo olukhulu ekuqaleni. Kodwa akukho nto ibalulekileyo, njengoko uza kunikwa amayeza afunekayo kwangaphambili ukuthintela i-allergies enzulu.
Iintsuku zokuphumla
Kwimijikelo eqhelekileyo, uya kuba neentsuku ezili-16 zokuphumla emva konyango. Umzimba uziva udiniwe kakhulu njengoko unyango lwe-R-CHOP lutshabalalisa iiseli zomhlaza. Ngoko ke kuqhelekile ukuziva udiniwe kakhulu kwezi ntsuku. Ngeli xesha, kulungile kakhulu ukucela uncedo kusapho nakubahlobo ngemisebenzi yemihla ngemihla.
Ngezi ntsuku zokuphumla, ukuba uziva ukulungele, ugqirha ucebisa ukuba wenze umthambo olula, njengokuhamba. Kubaluleke kakhulu ukusela amanzi amaninzi nokutya ukutya okunesondlo .
Zithini iingozi kunye nemiphumo emibi yolu nyango?
Njengalo naluphi na unyango, i-R-CHOP inokubangela iziphumo ebezingalindelekanga. Kodwa khumbula, ugqirha wakho uza kukunika amayeza owadingayo ukuthintela okanye ukulawula uninzi lweziphumo ebezingalindelekanga. Asinguye wonke umntu ofumana zonke ezi ziphumo ebezingalindelekanga. Ziyahluka kumntu nomntu. Makhe sijonge ezinye zezona ziphumo bezingalindelekanga ziqhelekileyo.
| Iziphumo ebezingalindelekanga eziqhelekileyo | Oko kufuneka ukwazi noko ukwenzayo |
|---|---|
| Umchamo obomvu/opinki | I-Doxorubicin ibomvu ngombala. Umchamo wakho unokuba bomvu/pinki ukuya kuthi ga kwiiyure ezingama-48 emva konyango. Oku kuqhelekile, ungakhathazeki. |
| Isicaphucaphu nokuhlanza | Nokuba usela amayeza okunyanga isicaphucaphu, usenokuziva unesicaphucaphu kancinci. Endaweni yokutya ukutya okukhulu, okunamafutha, okuneziqholo, yitya ukutya okuncinci, rhoqo. |
| Ukulahleka kweenwele | Oku kuqhelekile kwi-chemotherapy. Ukulahleka kweenwele kunokuqala kwiiveki ezintathu emva kokuthatha idosi yokuqala. Nangona kunjalo, iinwele ziyakhula kwakhona emva kokuba unyango luphelile. |
| Ukugodola kunye nomkhuhlane | Unyango lwe-chemotherapy lunokunciphisa inani leeseli ezimhlophe zegazi lakho, nto leyo eyandisa umngcipheko wokosuleleka. Uza kunikwa inaliti ebizwa ngokuba yi-G-CSF, enceda iiseli zakho ezimhlophe zegazi zikhule. Nangona kunjalo, ukuba unesicaphucaphu, xelela ugqirha wakho ngoko nangoko. |
| Ukudinwa kakhulu (Ukudinwa) | Unyango lunokubangela ukwehla kweeseli ezibomvu zegazi, nto leyo enokubangela i-anemia. Ukuba uziva udiniwe, phumla. Cela uncedo ngemisebenzi yemihla ngemihla. |
| Ukukrweleka/ukopha okulula | Le meko inokwenzeka ngenxa yokuncipha kweeplatelets. Lumka ungonzakali. Xelela ugqirha wakho ukuba ubona imivumbo emininzi emzimbeni wakho. |
| Ukungaziva/ukurhawuzelela kwamalungu omzimba | Oku kubizwa ngokuba yi-peripheral neuropathy. Ukuba uziva urhawuzelelwa okanye utshile ezandleni okanye ezinyaweni zakho, xelela ugqirha wakho. |
Khumbula, umkhuhlane unokuba luphawu losulelo olukhulu. Ukuba umkhuhlane wakho ungaphezulu kwe-100.4°F (38°C), fowunela ugqirha wakho okanye isibhedlele ngokukhawuleza.
Ukongeza kwezi, usenokuba nezilonda emlonyeni, ukurhawuzelelwa lusu, intloko ebuhlungu, ukuqhina okanye urhudo, iintlungu zesifuba, ukungalali, kunye nokutshintsha kweemvakalelo. Thetha nogqirha wakho ngayo nayiphi na kwezi.
Ndifanele ndimtsalele umnxeba nini ugqirha?
Xelela ugqirha wakho ngokukhawuleza ukuba ufumanisa naziphi na iimpawu ezintsha okanye ukuba naziphi na iimpawu zakho ziba mandundu ngexesha lonyango, ingakumbi ukuba unesifo somkhuhlane.
Kwimeko yongxamiseko efana nobunzima bokuphefumla okanye iintlungu zesifuba ngequbuliso, yiya kwiSebe lezeMpilo eziNgxamisekileyo (ETU) lesibhedlele esikufutshane ngoko nangoko.
Ndingenza njani ukuba eli xesha lonyango libe lula kum?
Le mfazwe ayifanele uyilwe wedwa. Zimbalwa izinto onokuzenza ukuze wenze eli xesha libe lula.
- Yaziswa: Thetha nogqirha wakho malunga nonyango lwakho kunye noko unokukulindela. Musa ukoyika ukubuza imibuzo.
- Cela uncedo: Cela uncedo kusapho nakubahlobo ngemisebenzi yasekhaya, ekulungiseleleni ukutya, nasekuyeni esibhedlele.
- Yitya kwaye usele kakuhle: Yitya ukutya okunesondlo. Sela amanzi amaninzi kunye nolwelo.
- Fumana inkxaso: Buza ugqirha wakho malunga namaqela enkxaso apho abanye abafumana unyango olufanayo nolwakho bejongene nomhlaza. Kungumthombo wamandla ukuba nomntu onokubelana naye ngamava akho.
Iiveki zokuqala zonyango lwe-R-CHOP zinokuba lixesha elinzima. Iintsuku zamayeza zinokuba zinde kwaye iziphumo ebezingalindelekanga zinokuba nzima ukujongana nazo. Kodwa kubantu abaninzi, iziphumo ze-R-CHOP zibaluleke kakhulu. Ukudibanisa la mayeza mathathu (ajoliswe kuwo, i-chemo, kunye ne-steroids) kusebenza ukubulala iiseli zomhlaza ngempumelelo kakhulu. Ngokuxhomekeke kwisifo sakho, oku kunokukhokelela ekuphumleni ngokupheleleyo komhlaza.
Umyalezo Wokuya Ekhaya
- I-R-CHOP yindibaniselwano esebenzayo kakhulu yamayeza ama-5 asetyenziselwa ukunyanga umhlaza njenge-non-Hodgkin lymphoma.
- Unyango lunikwa “ngemijikelo.” Ngeli xesha, kuqhelekile ukuba neziphumo ebezingalindelekanga ezifana nokudinwa, isicaphucaphu, kunye nokulahlekelwa ziinwele.
- Iziphumo ezininzi ezingalindelekanga zinokulawulwa. Soloko uthetha neqela lakho lezonyango ngazo.
- Ukuba uqalisa ukuba nomkhuhlane ngexesha lonyango, cinga ukuba yingxamiseko kwaye ufune ingcebiso kagqirha ngoko nangoko.
- Akunyanzelekanga ukuba uhambe wedwa kolu hambo. Fumana inkxaso kusapho, kubahlobo, nakwiqela lakho lezonyango. Unamandla. Ungakwenza oku.
I-R-CHOP, umhlaza, i-Non-Hodgkin lymphoma, i-chemotherapy, unyango olujoliswe kulo, unyango lomhlaza, iziphumo ebezingalindelekanga
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho