Ngaba ugqirha wakho ukunike iyeza elibizwa ngokuba yiTamoxifen njengonyango lomhlaza webele? Okanye uxelelwe ukuba ulisebenzise eli yeza ukuze ulithintele kuba usengozini enkulu yokuba nomhlaza webele? Usenokuba uzive usoyika kancinci xa usiva eli gama. Usenokuba nemibuzo emininzi efana nethi, "Luhlobo luni lweyeza eli? Kuza kwenzeka ntoni kum?" Yinto eqhelekileyo leyo. Ke namhlanje, masithethe ngokuba yintoni iTamoxifen, indlela esebenza ngayo emzimbeni wethu, zithini izibonelelo zayo, kunye neziphumo ebezingalindelekanga ekufuneka uzazi ngendlela elula neqondakalayo.
Yintoni iTamoxifen? Isebenza njani?
Ngamafutshane, iTamoxifen liyeza elithintela ukusebenza kwehomoni yabasetyhini i-estrogen emizimbeni yethu. Ngoku mhlawumbi ucinga, "Uyinyanga njani umhlaza ngokuthintela ihomoni?"
Cinga ngale ndlela. Ezinye iiseli zomhlaza wamabele zifana nezityalo ezincinci. Ezi zityalo zifuna 'amanzi' ukuze zikhule, zikhule, zisasazeke. Kwimeko enjalo, loo 'manzi' yi-hormone estrogen. Ezi ntlobo zeeseli zomhlaza zikhula ngokukhawuleza xa zifumana i-estrogen.
I-Tamoxifen liyeza elilula kakhulu. Kufana nokucima amanzi angena kwiseli yomhlaza. Ngamanye amazwi, ithintela amandla e-hormone estrogen okunamathela kwiseli yomhlaza. Ngoko ke ngaphandle kwe-estrogen, iiseli zomhlaza azinakukhula. Akunjalo kuphela, kodwa ngamanye amaxesha i-Tamoxifen inokubulala neeseli zomhlaza ezingaxhomekekanga kwi-estrogen.
Kangangeminyaka engaphezu kwama-30, oogqirha bebesebenzisa eli yeza ngempumelelo ukunyanga umhlaza webele oxhomekeke kwi-estrogen.
Ziziphi iimeko apho oogqirha bamisela iTamoxifen?
I-Tamoxifen ayiloyeza elinikwa ngesizathu esinye kuphela. Kusenokuba nezizathu ezininzi zokuba unikwe eli yeza. Makhe sijonge ukuba lisetyenziselwa ntoni na.
| Imeko yokusetyenziswa | Ingcaciso elula |
|---|---|
| Ukunyanga umhlaza webele nokuthintela ukuphinda kwawo ubuye | Eli yeza linikwa ukunciphisa umngcipheko wokubuya komhlaza emva kotyando okanye unyango lwemitha. |
| Ukuthintela umhlaza kwelinye ibele ukuba ungasasazeki uye kwelinye ibele | Oku kunceda ukunciphisa umngcipheko womhlaza kwelinye ibele eliphilileyo kumntu okhe waba nomhlaza kwelinye ibele. |
| Ukuthintela umhlaza kwabo basengozini enkulu | Inikwa njengendlela yokuthintela abasetyhini abangenayo imbali yomhlaza webele kodwa abasengozini enkulu ngenxa yezizathu ezifana nembali yosapho. |
| Ukunyanga umhlaza wesigaba sokuqala (i-DCIS) | Inikwa emva kotyando lweDuctal Carcinoma in Situ (DCIS), inqanaba lokuqala lomhlaza webele. |
| Kweminye imihlaza | Ngamanye amaxesha ikwasetyenziswa nakwezinye iintlobo zomhlaza, njengomhlaza wesibeleko kunye nomhlaza wesibeleko. |
| Kwiingxaki zokuzala | Kukho iimeko apho eli yeza likwasetyenziswa ukulawula ukukhutshwa kweqanda kwabanye abafazi. |
Enye inzuzo ekhethekileyo yeTamoxifen kukuba ingasetyenziswa kumanqanaba angaphambi kokuya exesheni nasemva kokuya exesheni ebomini bomfazi.
Zithini iziphumo ebezingalindelekanga zeTamoxifen? Ngaba kufuneka soyike?
Njengayo nayiphi na imithi, iTamoxifen inokubangela ezinye iziphumo ebezingalindelekanga. Kodwa into ebalulekileyo ekufuneka uyiqonde apha kukuba kwiimeko ezininzi, iingenelo zale mithi zingaphezulu kakhulu kuneengozi zeziphumo ebezingalindelekanga, ingakumbi xa kunyangwa umhlaza.
Iziphumo ebezingalindelekanga zingahlulwahlulwa zibe ziindidi ezimbini.
1. Iziphumo ebezingalindelekanga ezinzulu, kodwa ezingaqhelekanga
Amathuba okuba ezi zinto zenzeke aphantsi kakhulu, kodwa ukuba ziyenzeka, kufuneka ufune ingcebiso kagqirha ngoko nangoko.
- Amahlwili egazi: ingakumbi emilenzeni okanye emiphungeni.
- Izibetho
- Umhlaza wesibeleko:Lo mngcipheko mncinane kakhulu, ngoko ke kufuneka uxelele ugqirha wakho ukuba unayo nayiphi na into engaqhelekanga yokopha kwilungu lobufazi.
- IiCataracts
2. Iziphumo ebezingalindelekanga eziqhelekileyo nezingembi kangako
Ezi zifana neempawu ezenzeka ngexesha lokuya exesheni.
- Ubushushu obugqithisileyo: Ukuziva ubushushu nokubila ngequbuliso.
- Ukoma kwesisu
- Ukuqaqamba kwemilenze
- Intlungu yamalungu
- Abanye abantu banokuba nemijikelo yokuya exesheni engacwangciswanga kakuhle kunye neengxaki ezithile ngobomi babo besondo.
Eyona nto ibalulekileyo kukuthetha nogqirha wakho ukuba uziva into engaqhelekanga ngolu hlobo, nokuba incinci okanye inkulu kangakanani. Zikho iindlela zokulawula ezi zinto.
Isebenza kangakanani iTamoxifen ekuthinteleni umhlaza?
Uphando lufumanise ukuba xa abafazi abasengozini enkulu yomhlaza webele bethatha iTamoxifen iminyaka emi-5, umngcipheko wabo wokuba nomhlaza uyancipha malunga nama-50%. Oko kuphantse kube sisiqingatha!
Kufunyenwe nenye inzuzo eyongezelelweyo: Eli yeza linciphisa umngcipheko wokuqhekeka kwesinqe, esihlahleni, kunye nomqolo okubangelwa yi-osteoporosis.
Nangona kunjalo, xa ekunika eli yeza ngenjongo yokuthintela umhlaza, ugqirha uya kwenza isigqibo emva kokuqwalasela imeko yakho yempilo iyonke, izinto ezinobungozi, kunye nemiphumo emibi yale yeza.
Umyalezo Wokuya Ekhaya
- I-Tamoxifen liyeza elibaluleke kakhulu elithintela ukukhula kweeseli zomhlaza webele ezixhomekeke kwi-hormone ye-estrogen.
- Isetyenziselwa ukunyanga umhlaza webele, ukuthintela umhlaza ukuba ungabuyi, kunye nokuthintela umhlaza ukuba ungaphuhli kubantu abasengozini enkulu.
- Njengazo zonke amayeza, le inokuba nemiphumo emibi. Nangona kunjalo , iingenelo zokunyanga umhlaza zihlala zingaphezulu kakhulu kuneengozi zemiphumo emibi.
- Ungaze ulibale ukuxelela ugqirha wakho ngazo naziphi na iziphumo ebezingalindelekanga ozifumanayo, nokuba zincinci kangakanani na.
- Wena nogqirha wakho nifanele nixoxe ngezinto ezilungileyo nezingalunganga zale mithi kunye ukuze nenze isigqibo esifanelekileyo. Ningaze ningoyiki okanye nithandabuze.
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