Okudingeka ukwazi ngokuhlolwa kwe-ACTH

Ingabe udokotela wakho ukutshelile ukuthi wenze ukuhlolwa kwe-ACTH? Ungase ukhathazeke kancane uma uzwa igama. Ungase ucabange, "Luhlobo luni lokuhlolwa okungajwayelekile lolu?" Kodwa asikho isidingo sokwesaba. Kuwukuhlolwa kwegazi okulula kakhulu. Namuhla, sizoxoxa ngokuhlolwa kwe-ACTH, ukuthi kwenziwa kanjani, nokuthi ungakulungiselela kanjani ngendlela elula kakhulu ongayiqonda.

Kalula nje, iyini i-ACTH?

Kulungile, ake sikucabange ngale ndlela. Umzimba wakho ufana nenkampani enkulu. Kunezinto eziningi ezibalulekile ezenzekayo kule nkampani.

• Umphathi Oyinhloko: Ngaphansi kobuchopho bakho, kukhona indlala encane engangosayizi wephizi encane. Lokhu sikubiza ngokuthi indlala ye-pituitary. Lona umphathi oyinhloko wendaba yethu.
• Umlayezo: Lo mphathi, i-pituitary gland, uthumela umyalezo okhethekile. Lowo myalezo yilokho esikubiza ngokuthi i-ACTH (i-Adrenocorticotropic hormone).
• Isisebenzi: Lo myalezo we-ACTH uya ngqo ezindlaleni ezimbili ezincane phezu kwezinso zakho. Sizibiza ngokuthi izindlala ze-adrenal. Laba yizisebenzi zendaba yethu.
• Umkhiqizo: Lapho kutholwa umyalezo we-ACTH, la ma-adrenal glands akhiqiza i-hormone ebaluleke kakhulu ebizwa ngokuthi i-cortisol.

Ngakho-ke i-ACTH yi-hormone esitshela ukuthi senze i-cortisol. Le hormone ye-cortisol ibaluleke kakhulu emizimbeni yethu. Isisiza ukulawula umfutho wegazi wethu , siphendule kahle ezifweni , futhi isisize sihlukanise ushukela, amafutha, namaprotheni ekudleni esikudlayo kube amandla .

Uyaqonda manje? Uma udokotela wakho esola ukuthi kukhona okungahambi kahle ngalesi simiso, uzokucela ukuthi uhlole igazi ukuze uhlole amazinga akho e-ACTH kanye ne-cortisol.

Kungani udokotela angancoma lolu vivinyo?

Ukuhlolwa kwe-ACTH akuvamile ukwenziwa kodwa. Cishe njalo kwenziwa kanye nokuhlolwa kwe-cortisol. Lokhu kungenxa yokuthi izimpawu esizizwayo lapho amazinga e-ACTH ephezulu noma ephansi zihlobene ngqo noshintsho emazingeni e-cortisol.

Manje ake sibone ukuthi lezi zici ziyini.

Ngokubheka lezi zimpawu nokuhlola amazinga akho e-ACTH kanye ne-cortisol, udokotela wakho anganquma ukuthi unanoma yiziphi izimo ezilandelayo:

• I-Cushing's syndrome: Amazinga aphezulu e-cortisol emzimbeni.
• Isifo sika-Addison: Amazinga e-cortisol aphansi kakhulu emzimbeni.
• Kungakhathaliseki ukuthi kukhona isimila e-pituitary gland noma kwenye indawo .
• Kungakhathaliseki ukuthi izindlala zakho ze-pituitary noma ze-adrenal azisebenzi kahle.

Ungalungiselela kanjani ukuhlolwa?

Ukuze uthole umphumela onembile kulolu vivinyo, udinga ukulungiselela kancane. Landela lezi zinyathelo kahle.

• Ama-Steroids: Uma uthatha ama-steroid (isib. i-Prednisolone), kuzodingeka uyeke ukuwathatha cishe emahoreni angu-48 ngaphambi kokuhlolwa. Le mithi ingathinta imiphumela. Kodwa-ke, ungalokothi uyeke ukuwathatha ngaphandle kokubonisana nodokotela wakho kuqala. Uzokweluleka ngalokhu.
• Ukudla Nokuphuza: Udokotela wakho angase akutshele ukuthi ungadli noma uphuze lutho ngemva kwamabili ebusuku ngaphambi kokuhlolwa. Ngezinye izikhathi, bazokutshela nokuthi unciphise ukudla okunama-carbohydrate amaningi (ama-starch) cishe izinsuku ezimbili ngaphambi kokuhlolwa.
• Lala kahle: Lala kahle ebusuku ngaphambi kokuhlolwa.
• Ukuzivocavoca: Gwema ukuzivocavoca okunzima amahora ayi-12 ngaphambi kokuhlolwa.
• Ukucindezeleka: Zama ukuphumula ngangokunokwenzeka. Gwema ukucindezeleka ngokweqile amahora ayi-12 ngaphambi kokuhlolwa.

Indlela yokwenza isivivinyo kanye nezingozi

Lokhu kulula kakhulu. Njengokunikela ngegazi okuvamile, umhlengikazi uzothatha isampula encane yegazi emthanjeni osengalweni yakho.

Ngenxa yokuthi amazinga ethu ama-hormone ayashintsha phakathi nosuku, udokotela wakho angase acele ukuhlolwa kwegazi kanye ekuseni bese ephinda futhi kusihlwa . Amazinga e-ACTH avame ukuba phezulu cishe ngo-8 ekuseni bese ehla kusihlwa. Lokhu kuhlola kabili kusiza udokotela wakho ukuthola isithombe esiphelele.

Ngemva kokukhishwa kwegazi, isampula ifakwa ngokushesha eqhweni bese ithunyelwa elabhorethri.

Izingozi zimane nje ziyizingozi ezivamile zokukhishwa kwegazi ngenaliti. Lokho kusho ubuhlungu obuncane endaweni yenaliti, ukuklwebheka okuncane, noma, okungajwayelekile, ukutheleleka.

Ungayiqonda kanjani imiphumela?

Amanani embikweni wakho wokuhlolwa angahluka kancane kusuka kwelinye ilabhorethri kuya kwelinye. Imiphumela iyahlukahluka kuye ngesikhathi igazi elikhishwe ngaso.

Ngokuvamile, amazinga e-ACTH kumuntu omdala onempilo aphakathi kuka-10-50 pg/mL (ama-picogram nge-milliliter) cishe ngo-8 ekuseni. Ngobusuku, lokhu kwehla kube ngaphansi kuka-5-10 pg/mL.

Kodwa ungasheshi ufinyelele eziphethweni ngokusekelwe kulezi zinombolo. Ezinye izici zingathinta imiphumela yakho.

• Indlela olale ngayo ngobusuku bangaphambi kokuhlolwa.
• Ukucindezeleka okungaphansi kwakho.
• Kungakhathaliseki ukuthi ukhulelwe noma usesikhathini.
• Eminye imithi oyithathayo (isib. ama-hormone, i-insulin, ama-steroid).
• Ingozi yomzimba noma ukulimala kwamuva nje.
• Ukuthi isampula yegazi iqoqwe kahle futhi yagcinwa eqhweni.

Udokotela wakho uzoqhathanisa umbiko we-ACTH nombiko we-cortisol bese ewufanisa nezimpawu zakho ukuze afinyelele esiphethweni sokugcina. Uma kukhona okungajwayelekile ezingeni lakho le-ACTH, angase acele ukuhlolwa okwengeziwe ukuze kutholakale imbangela eqondile.