Ake sifunde ngomdlavuza webele kanye ne-BRCA gene endabeni yomlingisi odumile.

Cishe ungumbukeli wama-movie nochungechunge lwethelevishini lwaseHollywood. Khona-ke cishe uyamkhumbula umlingisi uChristina Applegate. Umlingisi onekhono kakhulu nodumile. Kodwa ngemuva kwalowo buso obumomothekayo, kunendaba enzima kakhulu abhekana nayo empilweni yakhe, futhi singafunda okuningi kuyo. Namuhla sikhuluma ngalokho. Lena akuyona nje indaba yomlingisi, kodwa isifundo esivula amehlo mayelana nomdlavuza webele kanye nezingozi zofuzo ezihambisana nawo.

Umdlavuza webele eneminyaka engu-36... Kungani lokhu kwenzeka?

Cabanga nje, ubungazizwa kanjani uma utholakale unomdlavuza webele uneminyaka engu-36, empilweni yakho yonke? UChristina kwadingeka abhekane nalolo lwazi. Kodwa lokhu akukusha emndenini wakhe. Unina naye wayenomdlavuza webele esemncane. Ngenxa yalo mlando womndeni, uChristina ubelokhu ehlolwa njalo umdlavuza webele kusukela eneminyaka engu-30. Lena yinto ebaluleke kakhulu eyasindisa impilo yakhe. Lokhu kusibonisa ukuthi kubaluleke kangakanani ukuqaphela uma othile emndenini wakho enomdlavuza futhi ahlolwe kusenesikhathi ngeseluleko sikadokotela. Ngisho noma ukuxilongwa kuqinisekisile ukuthi wayenomdlavuza ebeleni elilodwa kuphela, wenza isinqumo esinesibindi kakhulu. Lokho kwakuwukususwa kwamabele womabili ngokuhlinzwa ("i-double mastectomy"). Abantu abaningi bangase bazibuze, "Kungani wenze isinqumo esinjalo?" Isizathu salokhu umphumela wokuhlolwa kwakhe kwezakhi zofuzo.

Kuyini lokhu kuguqulwa kwezakhi zofuzo ze-BRCA?

Ake sikubeke kalula. Umzimba wethu ufana nesakhiwo esakhiwe ngendlela ehlelekile. Konke kulesi sakhiwo kulawulwa "yipulani" ebizwa ngokuthi izakhi zofuzo zethu. Ezinye zalezi zakhi zofuzo zifana "nabalindi" abavimba amangqamuzana omzimba wethu ekuhlukaneni ngokungalawuleki futhi bavimbele ukwakheka komdlavuza. I-BRCA1 ne-BRCA2 ziyizakhi zofuzo ezimbili ezinjalo. Uma nje zisebenza kahle, zinciphisa ingozi yokuthola umdlavuza webele nowesibeletho. Kodwa ngezinye izikhathi lezi zakhi zofuzo zingaba "eziguqukile" noma ezinephutha. Cabanga ngalokho okwenzekayo lapho uhlelo lwamabhuleki emoto luphuka. Imoto ayikwazi ukuma. Ngokufanayo, lapho kwenzeka ushintsho ku-BRCA gene, ilahlekelwa amandla ayo okuvimba amangqamuzana omdlavuza ekukhuleni. Ukuhlolwa kwezakhi zofuzo kukaChristina kuqinisekisile ukuthi une-BRCA1 gene mutation. Bheka ithebula elingezansi ukuze ubone ukuthi le ngozi ibukeka kanjani. Manje usuyabona ukuthi kungani uChristina anquma ukususwa womabili amabele? Ukuze agweme ingozi enkulu yokuba nomdlavuza kwelinye ibele esikhathini esizayo. Futhi, ngo-2017, wahlinzwa okunye okukhulu. Lokho kwakuwukususa ama-ovari akhe nama-tubes e-fallopian. Lokho kwakuwukugwema ingozi enkulu yokuba nomdlavuza we-ovari. Lezi izinqumo ezinzima kakhulu, zomuntu siqu. Kodwa wakwenza konke lokhu ngokubonisana nodokotela bakhe, nangolwazi oluphelele ngalesi simo.

Ukulwa nomdlavuza nendlela yokuphila

Impi kaChristina ayizange iphele ngokuhlinzwa. Wayishintsha ngokuphelele indlela yakhe yokuphila.

Ukudla okunempilo

Into eyodwa ayishoyo njalo ukunciphisa inani lokudla okuqukethe amakhemikhali kanye nezilondolozi ngangokunokwenzeka. Kunalokho, uhlala egcizelela ukubaluleka kokudla ukudla kwemvelo okuningi njengezithelo nemifino emisha .

Ukuphathwa kokucindezeleka

Ngaphambi komdlavuza, wayengumuntu "ocindezeleke kakhulu". Kodwa ngemva kwalokhu okuhlangenwe nakho, waqaphela ukubaluleka kokulawula ukucindezeleka. Manje uzama ukubona "uhlaka oluhle" kukho konke. Impilo yethu yengqondo ithinta ngqo amasosha omzimba. Ngakho-ke, ukuhlala sizolile ngokwengqondo nakho kuyasiza ekulweni nezifo.

Ukusiza abanye

UChristina, owayenomuzwa wokuthi bekungeke kube ukulunga ukuvumela lokho adlule kukho kwenzeke komunye umuntu, waze waqala inhlangano ebizwa ngokuthi "Isenzo Esifanele Sabesifazane." Le nhlangano inikeza usizo lwezezimali kwabesifazane abasengozini enkulu yomdlavuza ukuze bahlolwe ngendlela ebiza kakhulu, njenge-MRIs.

Enye inselele empilweni kanye nesibindi sengqondo esingantengantengi

Ngokuhamba kwesikhathi, impilo kaChristina yafika nenye inselele. Lokho kwaba ukuxilongwa ukuthi unesifo esibizwa ngokuthi "Multiple Sclerosis (MS)``, esithinta uhlelo lwezinzwa. Ukuphila nalokhu kunzima kakhulu. Kodwa akazange ayeke. Wathi, "Lo mgwaqo unzima kakhulu. Kodwa sonke siyazi, umgwaqo uyaqhubeka." Lawa magama ambalwa asinika umbono wamandla akhe engqondo angaguquki.

Lokho esingakufunda endabeni kaChristina

Kunezifundo ezibalulekile eziningana okufanele uzithathe kule ndaba. 1. Yazi umlando womndeni wakho: Ingabe umama wakho, udadewenu, u-anti wakho, noma ugogo wakho babenomdlavuza webele noma umdlavuza wesibeletho? Uma kunjalo, qiniseka ukuthi ukhuluma nodokotela wakho ngakho. 2. Ukutholwa kusenesikhathi kusindisa izimpilo: Uma udokotela wakho ekuncoma, thola izivivinyo ezifana ne-"mammogram" ngesikhathi. Futhi, funda ukuthi ungazenza kanjani izivivinyo zebele ekhaya. Uma uzizwa noma yiziphi izinguquko noma amaqhubu , ungesabi futhi ubone udokotela ngokushesha. 3. Ukuhlolwa Kwezakhi Zofuzo: Uma unomlando oqinile womndeni womdlavuza, buza udokotela wakho mayelana nokuhlolwa kwezakhi zofuzo njenge-BRCA. Akuwona wonke umuntu okudingayo lokhu, kodwa kungabaluleka kakhulu kulabo abasengozini enkulu. 4. Indlela yokuphila enempilo: Ukudla okunempilo, ukuzivocavoca umzimba, kanye nokulawula ukucindezeleka kuyizivikelo ezinhle kakhulu kunoma yisiphi isifo.