Ngezinye izikhathi, imizwa yethu yokudabuka, ukukhathazeka, kanye nokungabi namandla iba namandla kangangokuthi asisakwazi ngisho nokwenza imisebenzi yethu yansuku zonke. Ngezikhathi ezinjalo, uma ubona udokotela, angakuxilonga ukuthi unesifo sokucindezeleka futhi akunikeze ukwelashwa. I-Desipramine umuthi ovame ukusetshenziselwa ukwelapha ukucindezeleka. Ngakho-ke uma wena noma othile oseduze nawe enikezwe lo muthi, kubalulekile ukuqaphela.
Kuyini i-Desipramine?
Kalula nje, i-Desipramine umuthi osetshenziselwa ukwelapha ukucindezeleka. Ubuchopho bethu bukhiqiza ngokwemvelo izithunywa zamakhemikhali. Sibiza lawa ma-neurotransmitter. I-Serotonin ne-Norepinephrine ngamakhemikhali amabili amakhulu alawula imizwa yethu, okusho injabulo yethu, ukuzola, kanye namazinga omsebenzi.
Ukucindezeleka kubangelwa ukungalingani kwala makhemikhali. I-Desipramine isebenza ngokwandisa amazinga e-serotonin ne-norepinephrine ebuchosheni, okusiza ukubuyisela ukusebenza kwawo. Lo muthi ungowesigaba semithi ebizwa ngokuthi ama-tricyclic antidepressants (TCAs) .
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuthatha lo muthi
Ngaphambi kokuqala i-Desipramine, kubalulekile ukunikeza udokotela wakho isithombe esiphelele ngesimo sakho sempilo. Lo muthi ungase ungahambisani nezinye izimo zezokwelapha. Uma unezinye zezimo ezilandelayo, qiniseka ukuthi wazisa udokotela wakho.
| Isimo noma umkhuba | Kungani udinga ukutshela udokotela? |
|---|---|
| Uma unesifo senhliziyo noma uhlaselwe yinhliziyo ngaphambilini | Lo muthi ngezinye izikhathi ungathinta izinga lokushaya kwenhliziyo. |
| Imicabango yokuzibulala, imizamo yangaphambilini, noma umlando womndeni wokuzibulala | Imithi yokwelapha ukucindezeleka, ikakhulukazi ezigabeni zokuqala, ingandisa le micabango kwabanye abantu, ngakho-ke kudingeka ukunakwa okuseduze. |
| Ezinye izifo zengqondo, njenge-bipolar disorder noma i-schizophrenia | Lomuthi ungashintsha noma wenze lezo zimpawu zibe zimbi kakhulu. |
| Isifo sesibindi | Lomuthi ususwa emzimbeni yisibindi. Uma ukusebenza kwesibindi kukubi, umuthi unganqwabelana emzimbeni. |
| Isimo se-Glaucoma | Lomuthi ungase wandise ukucindezeleka kwamehlo. |
| Ubunzima bokuchama, izinkinga ze-prostate | Imithi ingenza lesi simo sibe sibi kakhulu. |
| Isithuthwane noma ukuxhuzula (Ukuxhuzula) | Lo muthi ungandisa kancane ingozi yokuquleka. |
| Inkinga yokuphuza | Ukuhlanganisa utshwala nalo muthi kungandisa ukozela kanye neminye imiphumela emibi. |
| Uma ukhulelwe, uzama ukukhulelwa, noma uncelisa | Kufanele uxoxe nodokotela wakho ukuthi umuthi ungamthinta yini umntwana. |
| Ukungezwani neminye imithi, ukudla, kanye nodayi | Ukuthola ukuthi une-allergy yini ku-desipramine noma kunoma yiziphi izithako zayo. |
Ngiyisebenzisa kanjani ngempela le mithi?
Kubaluleke kakhulu ukuthatha isilinganiso esifanele ngesikhathi esifanele, njengoba nje udokotela emyalile.
- Gwinya leli philisi ngengilazi yamanzi.
- Zijwayeze ukuphuza imithi yakho ngesikhathi esifanayo nsuku zonke, njengoba udokotela wakho ekuyalele.
- Ungathathi imithi engaphezu kwalokho okuyalelwe.
- Into ebaluleke kakhulu ukungayeki ukuthatha lo muthi ngokuzumayo ngaphandle kweseluleko sikadokotela wakho. Uma wenza kanjalo, ungase ube nezimpawu zokuhoxa ezifana nokuzungeza, isicanucanu, kanye nekhanda elibuhlungu. Noma isimo sakho singase sibe sibi kakhulu. Uma uyeka, yenza lokho njengoba kuqondiswe udokotela wakho, wehlise kancane kancane umthamo.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Uma ukhohlwa ukuthatha umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ubuyisele umthamo ophuthelwe.
Kuthiwani uma ngiphuza umuthi omningi kakhulu?
Uma usola ukuthi uthathe umuthi omningi kunalokho okucabangayo, ungawuthathi kalula. Yiya e- Emergency Treatment Unit (ETU) yesibhedlela ngokushesha. Noma shayela i-National Poisons Information Centre e-Colombo National Hospital .
Eminye imithi engasebenzisana ne-Desipramine
I-Desipramine ingasebenzisana neminye imithi eminingi, ngakho-ke kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa imithi kadokotela, imithi ethengiswa ngaphandle kwemithi kadokotela, imithi yendabuko, amavithamini, kanye nezithasiselo.
Ngezansi kunezibonelo ezimbalwa nje.
- Kuyingozi kakhulu ukuthatha i-Desipramine kanye neminye imithi yokucindezeleka efana ne-MAOIs (isib. i-Carbex, i-Marplan).
- Imithi yokwelapha izifo zengqondo njenge-phenothiazines (isb. i-perphenazine, i-chlorpromazine).
- Eminye imithi yesifo senhliziyo.
- Amanye ama-antibiotic, njenge-Linezolid.
- Ingasabela futhi nezithako ezitholakala kweminye imithi ethengiswa ngaphandle kwemithi kadokotela yomkhuhlane, ukukhwehlela, kanye nokungezwani komzimba.
Ngakho-ke, buza udokotela wakho njalo ngaphambi kokuqala noma yimuphi umuthi omusha.
Izinto okufanele uziqaphele uma usebenzisa umuthi
- Qaphela imicabango yakho: Emasontweni ambalwa okuqala okuqala umuthi wokucindezeleka, noma lapho ushintsha umthamo, abanye abantu bangase babe nemicabango yokuzibulala, ukukhathazeka, ukungakhululeki, kanye nokuphelelwa yithemba okungavamile. Uma wena noma umndeni wakho nibona noma yiluphi lwalezi zinguquko, khuluma nodokotela wakho ngokushesha.Ungesabi lokhu, kodwa kubalulekile ukuqaphela.
- Ukozela kanye nesiyezi: Lo muthi ungakwenza uzizwe ulele futhi unesiyezi. Ngakho-ke, gwema ukushayela, ukusebenza ezindaweni eziphakeme, noma ukusebenzisa imishini edinga ukuqaphela uze wazi ukuthi lo muthi uthinta kanjani wena. Ikakhulukazi uma ungumuntu osekhulile, sukuma uqonde lapho uvuka endaweni yokuhlala noma uvuka embhedeni.
- Utshwala: Gwema utshwala ngokuphelele ngenkathi uphuza i-desipramine. Utshwala bungandisa kakhulu imiphumela emibi yomuthi, ikakhulukazi ukozela.
- Umlomo owomile: Lokhu kuyimiphumela emibi evamile. Ungakulawula lokhu ngokuhlafuna itshungama engenashukela, ukumunca amaswidi angenashukela, nokuphuza amanzi usuku lonke.
- Ukuqunjelwa: Lo muthi ungabangela ukuqunjelwa. Kubalulekile ukudla ukudla okune-fiber eningi (izithelo, imifino) nokuphuza amanzi amaningi. Uma ungenawo umgudu wokugaya ukudla isikhathi esingaphezu kwezinsuku ezingu-2-3, tshela udokotela wakho.
- Ukuzwela kwelanga: Isikhumba sakho singase sizwele kakhulu ekukhanyeni kwelanga ngenkathi uthatha lo muthi. Ngakho-ke, sebenzisa isivikelo selanga futhi ugqoke izingubo ezimboza umzimba wakho uma uphuma elangeni.
Yimiphi imiphumela emibi engingayithola?
Njenganoma yimuphi umuthi, i-Desipramine ingabangela imiphumela emibi, yize kungebona bonke abantu abayitholayo. Ithebula elingezansi lichaza lokhu ngokucacile.
| Umphumela ongemuhle | Incazelo |
|---|---|
| Izinto okufanele uzibike kudokotela wakho ngokushesha | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi, nobunzima bokuphefumula. |
| Izinguquko ekushayeni kwenhliziyo | Ukuzizwa sengathi inhliziyo yakho ishaya ngokushesha, ukushaya kwenhliziyo okungajwayelekile, isiyezi, ubuhlungu besifuba. |
| I-Serotonin Syndrome | Ukungaphumuli, ukuqina kwemisipha noma ukuthuthumela, ukujuluka ngokweqile, umkhuhlane omkhulu, ukuxhuzula, ukuhlanza, uhudo. Lesi yisimo esiyingozi kakhulu. |
| Ukushintshashintsha okukhulu kwemizwa | Imicabango yokuzibulala, ukucindezeleka okukhulu, ulaka. |
| Ezinye izimpawu ezinkulu | Ukuquleka, ubuhlungu bamehlo obungazelelwe, ukubona okufiphele, ukungakwazi ukuchama. |
| Uma kuqhubeka noma kukhathaza, tshela udokotela wakho. | |
| Imiphumela emibi evamile | Umlomo owomile, ukozela, isiyezi, ukuqunjelwa, isicanucanu, ukuthuthumela. |
| Okunye | Izinguquko esifiso noma ekusebenzeni kocansi. |
Umlayezo Wokuya Nawe Ekhaya
- I-Desipramine iyimithi yokucindezeleka. Kungathatha amasonto ambalwa ukuzuza ngokugcwele kulo muthi. Ngakho-ke, bekezela futhi uphuze umuthi njengoba uyalelwe udokotela wakho.
- Ungayeki ukuthatha umuthi noma ushintshe umthamo nganoma yisiphi isizathu ngaphandle kweseluleko sikadokotela wakho.
- Yazisa udokotela wakho ngayo yonke eminye imithi oyithathayo (kufaka phakathi amavithamini nemithi yendabuko).
- Qaphela kakhulu imicabango nemizwa yakho lapho uqala ukuthatha lo muthi. Uma ubona noma yiziphi izinguquko ezingavamile, ikakhulukazi imicabango yokuzibulala, tshela udokotela wakho ngokushesha.
- Uma uphuza umuthi omningi kakhulu, iya ekamelweni lezimo eziphuthumayo esibhedlela (ETU) ngokushesha noma ushayele iNational Poisons Information Center .
👩🏽⚕️ Imibuzo eyengeziwe (ama-FAQ)
💬 Amaphilisi e-Desipramine / Norpramin anqunyelwe yisiphi isifo?
Lona omunye wemithi yezifo zengqondo endala kakhulu futhi enamandla kakhulu (i-TCA - Tricyclic Antidepressant) engasetshenziswa ukwelapha 'Ukucindezeleka Nokukhathazeka' okukhulu! Lokhu kuhlukile kancane kweminye imithi ye-TCA (njenge-Amitriptyline). Ngenkathi eminye yenza isiguli silale/silale, leli philisi linikeza isiguli 'umphumela wokuvuselela' futhi lisigcine sisebenza usuku lonke.
💬 Lo muthi (i-Desipramine) unikeza kanjani isiguli injabulo namandla ngesikhathi esisodwa?
Ukucindezeleka kubangelwa ukwehla kwamakhemikhali enjabulo ebuchosheni (i-Norepinephrine, i-Serotonin). Lokho okwenziwa yilo muthi ngokuyisisekelo (esikhundleni sokwandisa i-Serotonin) ukwandisa ukuhlushwa kobuchopho kwekhemikhali ebizwa ngokuthi 'i-Norepinephrine' ngo-100%, okuqeda isithukuthezi futhi kunike ubuchopho amandla kanye nekhono lokugxila entweni eyodwa. Yingakho odokotela bencoma lokhu ezigulini ezivilapha kakhulu futhi ezingakwazi ukuphuma embhedeni.
💬 Yimiphi imiphumela emibi eyinhloko kanye nezingozi eziyingozi kakhulu zalokhu?
Kunezingozi eziningi! (Imiphumela yokulwa ne-cholinergic). Lokhu kungabangela umlomo owomile, ubunzima bokuchama, kanye nesiyezi/ubuhlungwana lapho uvuka embhedeni. Enye ingozi eyingozi kakhulu ukuthi inomthelela omkhulu enhliziyweni! Kunengozi enkulu yokushintsha kwesigqi senhliziyo yesiguli futhi kubangele ukushaya kwenhliziyo okungavamile/okusheshayo (i-Arrhythmia/Tachycardia), okungaba yingozi.
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