Wake wezwa igama elithi DHT ? Mhlawumbe ulizwile ngesikhathi ukhuluma nomngane wakho ngokulahlekelwa izinwele , noma ufunda isihloko mayelana nempilo yamadoda . Iyini ngempela i-DHT? Ingabe ilungile noma imbi emizimbeni yethu? Le hormone ye-DHT abanye abantu abayesabayo empeleni yenzani emizimbeni yethu? Namuhla, sizokhuluma ngalokhu kalula, ngendlela ongayiqonda.
Kalula nje, iyini i-DHT?
Igama eliphelele le-DHT yi- Dihydrotestosterone . Nakuba leli gama liyinkimbinkimbi kancane, kulula kakhulu ukuliqonda ukuthi lisebenza kanjani. Cabanga ngama -hormone njengezithunywa ezincane ezisebenza ngaphakathi emizimbeni yethu. I-hormone ngayinye inomsebenzi wayo othize.
I-DHT ingenye yalezi hormone. Uma sikhuluma iqiniso, i-DHT ingeyeqembu lama-hormone abizwa ngokuthi ama-androgen . Umsebenzi oyinhloko wama-androgen ukudala nokugcina izici zesilisa.
I-androgen eyinhloko neyaziwa kakhulu emzimbeni wethu yi -testosterone . Cishe uke wezwa ngayo. Ngakho-ke, imizimba yethu iguqula cishe u-10% wale testosterone ibe yi-DHT, i-androgen enamandla kakhulu. Lokhu kuguqulwa kwenzeka esikhumbeni esizungeze izitho zangasese kanye ne-prostate gland kwabesilisa. Kwabesifazane, le nqubo iyenzeka nasesikhumbeni. Ngaphezu kwalokho, iyenzeka ngamanani amancane ezindaweni ezifana nesibindi sethu.
Ngenxa yokuthi amadoda ngokwemvelo anamazinga aphezulu kakhulu e-testosterone emizimbeni yawo, amazinga awo e-DHT nawo aphezulu kakhulu kunawabesifazane.
Yini eyenziwa yi-DHT emizimbeni yethu?
Indima ye-DHT iyashintsha ezigabeni ezahlukene empilweni yendoda. I-DHT iyi-hormone ebalulekile, ikakhulukazi ngesikhathi sokukhulelwa kanye nokuthomba.
Kodwa ngemva kokuba umuntu emdala, i-DHT ayidlali indima enkulu ekugcineni ukusebenza komzimba wesilisa njenge-testosterone. Lapho umuntu emdala, i-DHT ibangela kakhulu ukwandiswa kwe-prostate kanye nokulahlekelwa izinwele ngendlela yabesilisa.
Indima ye-DHT ekukhuleni komntwana esibelethweni
Uma umntwana esesibelethweni, ama-hormone amaningi adlala indima ekunqumeni ukuthi umntwana ungumfana noma intombazane. I-hormone ebizwa ngokuthi i-DHT ibalulekile ekuthuthukisweni okufanele kwezitho zangasese zomntwana womfana, okungukuthi, ipenisi kanye ne-scrotum. I-DHT isebenza njengomakhi oyinhloko ekwakheni indlu. I-DHT iyasiza futhi ekwakhekeni kwendlala ye-prostate .
I-DHT ngesikhathi sokuthomba
Ngemuva kwalokho, lapho umfana efika esikhathini sokuthomba, i-DHT iqala ukusebenza futhi. I-DHT ngokuyinhloko ibangela izinguquko eziningi ezenzeka emzimbeni womfana.
- Intshebe yobuso namadevu .
- Ukukhula kwezinwele kwezinye izingxenye zomzimba , njengesifuba namakhwapha.
- Ukukhula kwezinwele ezijiyile endaweni yesitho sangasese .
- Ukukhula okuqhubekayo kwendlala ye-prostate .
I-DHT inethonya elikhulu kukho konke lokhu.
Yiziphi izinkinga ezingavela uma amazinga e-DHT enyuka?
Nakuba i-DHT iyi-hormone ebalulekile uma ikhona emazingeni ajwayelekile, ingabangela izinkinga ezahlukene zempilo uma iba phezulu kakhulu. Ake sibheke ukuthi ziyini lezo.
| Isimo sempilo | Incazelo elula |
|---|---|
| I-Benign Prostatic Hyperplasia (BPH) | Isimo esivamile phakathi kwabesilisa abaneminyaka engaphezu kwengu-50. Indlala ye-prostate ikhiqiza i-DHT eningi kakhulu, okwenza indlala ikhule. Lokhu kungabangela ubunzima bokuchama (ukuchama njalo, ubunzima bokuchama). |
| Umdlavuza Wendlala Yesitho Sangasese | Amazinga aphezulu e-DHT atholakale ezigulini ezinomdlavuza wendlala. Uma amazinga aphezulu e-DHT ehlanganiswa nezinguquko ezithile zofuzo, amangqamuzana omdlavuza angakhula ngendlela engalawuleki. |
| Ukulahlekelwa izinwele (i-Androgenic Alopecia) | Lena yinto eyinhloko abantu abaningi abayaziyo. Kuyimbangela enkulu yokuba nempandla kwabesilisa. Lapho amazinga e-DHT enyuka, ama-follicle ezinwele ekhanda ayancipha. Isikhathi sokuphila kwezinwele siyafinyezwa, bese izinwele ziyawa bese izinwele ezintsha ezikhula kuzo ziba buthakathaka. |
| I-Polycystic Ovarian Syndrome (PCOS) | Lokhu ukungalingani kwama-hormone okuthinta abesifazane. Abesifazane abane-PCOS banokukhiqizwa ngokweqile kwama-hormone wesilisa (ama-androgens) njenge-testosterone ema-ovari abo. Lapho amazinga e-testosterone enyuka, amazinga e-DHT nawo ayanda. Lokhu kungaholela ezimpawini ezifana nokujikeleza kokuya esikhathini okungajwayelekile, induna, kanye nokukhula kwezinwele zomzimba okungafuneki. |
Into ebalulekile ukuthi uma izinwele zakho ziwa, akuyona i-DHT kuphela ebangela lokho. Izakhi zofuzo (izinto ezidluliselwa ezizukulwaneni ngezizukulwane) nezinye izinto eziningi zingadlala indima.
Kwenzekani uma amazinga e-DHT ehla?
Amazinga aphezulu naphansi e-DHT ayinkinga. Lesi simo sithinta kakhulu amadoda. Ake sibheke izimo zezokwelapha ezihambisana naso.
| Isimo sempilo | Incazelo elula |
|---|---|
| Ukuntuleka kwe-5-alpha reductase | Ngishilo ekuqaleni ukuthi i-DHT yenziwa nge-testosterone yi-enzyme ebizwa ngokuthi '5-alpha reductase'. Kwabanye abantu, ngenxa yezizathu zofuzo, le enzyme ayikhiqizwa emzimbeni noma ikhiqizwa kancane kakhulu. Ngenxa yalokho, amazinga e-DHT aba phansi kakhulu. Uma umntwana wesilisa ozalwe ngofuzo (i-XY chromosome) enalesi simo, izitho zangasese zangaphandle azikhuli kahle. Ngezinye izikhathi, zingase zibukeke njengentombazane ekuqaleni. |
| Amazinga aphansi e-testosterone (i-Hypogonadism yabesilisa) | Lokhu kulula kakhulu ukukuqonda. I-DHT ikhiqizwa yi-Testosterone. Ngakho-ke uma izinga le-testosterone lomuntu liphansi, izinga lakhe le-DHT lizoba phansi impela. Lokhu kungaholela ezinkingeni ezifana nokuncipha kwesifiso sobulili kanye nokwehla kwamandla omzimba. |
Okunye okwengeziwe mayelana nokuntuleka kwe-5-alpha reductase
Lokhu kuyinkimbinkimbi kancane, ngakho ake sichaze kabanzi. Uma ingane yowesilisa ngokwezakhi zofuzo (okungukuthi, ene-chromosome ye-XY) inalesi simo, izitho zangasese zangaphandle (ipenis, amasende) azikhuli ngoba i-DHT ayikhiqizwa esibelethweni.
Kodwa into emangalisayo ukuthi, amasende alawa bantwana akhule ngaphakathi emizimbeni yabo. Angakhiqiza nesidoda. Ngesikhathi sokuthomba, njengoba imizimba yabo ikhiqiza i-testosterone, kwenzeka izinto ezifana nokujula kwezwi, ukukhula kwemisipha, kanye nepenisi enkulu kancane. Kodwa ngenxa yokuthi ayikho i-DHT, izinto ezifana nokukhula kwentshebe nezinwele zomzimba azenzeki.
Ingabe kufanele ngibone udokotela mayelana namazinga ami e-DHT?
Uma unokungabaza ngamazinga akho e-DHT ngemuva kokufunda lesi sihloko, noma uma unezinye zezimpawu ezilandelayo, kungcono ukubona udokotela ukuze akunike iseluleko .
- Kwabesilisa: Uma ubhekene nokulahlekelwa izinwele ngokweqile, ubunzima bokuchama, noma ukungasebenzi kahle kocansi.
- Kwabesifazane: Uma umjikelezo wakho wokuya esikhathini ungajwayelekile, uma unezinwele ezingafuneki ezikhula ebusweni noma emzimbeni wakho, uma unezinduna eziningi neziqhubekayo (lezi kungaba izimpawu ze-PCOS).
- Kubazali: Uma ubona noma yikuphi ukubambezeleka noma ukungajwayelekile ekukhuleni kocansi kwengane yakho yowesilisa.
Sicela ukhumbule, ungazihloli noma ungaziphathi ngokusekelwe olwazini olutholakala ku-inthanethi. Ama-hormone omzimba wakho ayinkimbinkimbi kakhulu. Ngakho-ke, kubalulekile ukufuna iseluleko sochwepheshe wezokwelapha ofanelekayo nganoma yiziphi izinkinga.
Udokotela wakho uzokwenza ukuhlolwa kwegazi okuningana ukuze athole ukuqonda okunembile amazinga akho ama-hormone, uma kudingeka. Uma kudingeka, angakudlulisela kudokotela we-endocrinologist .
Umlayezo Wokuya Nawe Ekhaya
- I-DHT (i-Dihydrotestosterone) iyi-hormone yabesilisa enamandla kakhulu etholakala ku-testosterone.
- I-DHT ibalulekile ekukhuleni kobulili kowesilisa (esibelethweni kanye nasesikhathini sokuthomba).
- Amazinga aphezulu e-DHT angabangela ukulahlekelwa izinwele kwabesilisa, ukwanda kwe-prostate, kanye ne-PCOS kwabesifazane.
- Amazinga aphansi kune-DHT angase aphazamise intuthuko yocansi, ikakhulukazi kubafana.
- Uma unenkinga mayelana namazinga akho ama-hormone noma izimpawu ezihlobene, qiniseka ukuthi ubona udokotela wakho.
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