Wake wezwa igama elithi 'Methylene Blue'? Mhlawumbe akunjalo. Liwumuthi ongavamile kodwa obaluleke kakhulu. Ngokwesimo sawo somzimba, ubonakala njengoketshezi oluluhlaza okwesibhakabhaka olujulile. Nakuba ungase ubonakale njengodayi wendwangu ovamile, unamandla okwelapha izimo eziningana zezokwelapha ezimbi. Ake sibheke kabanzi indaba yalo muthi oluhlaza okwesibhakabhaka oyingqayizivele.
Iyini ngempela iMethylene Blue?
Kalula nje, i-Methylene Blue umuthi osetshenziswa odokotela ukwelapha isifo segazi esingavamile esibizwa ngokuthi i-methemoglobinemia . Nakuba kuyinhlanganisela eqinile, inikezwa njengesixazululo soketshezi oluhlaza okwesibhakabhaka ngomjovo ngqo emithanjeni yakho.
Umlando walesi sidakamizwa uyathakazelisa. Saqala ukutholwa yisazi semithi saseJalimane ngekhulu le-19. Ekuqaleni, sasisetshenziswa njengodayi embonini yezindwangu futhi kamuva njengombala wesikhumba ekuhlolweni kwelabhorethri.
Eminyakeni engaba ngu-125 eyedlule, udokotela waseJalimane waqala ukuyisebenzisa ukwelapha umalaleveva. Kusukela ngaleso sikhathi, ukusetshenziswa kwayo kwezokwelapha kuye kwashintsha kakhulu. Njengamanje, ivunyelwe yi-FDA ngqo ekwelapheni i-methemoglobinemia. Kodwa-ke, odokotela ngezinye izikhathi bangayisebenzisela ezinye izimo zezokwelapha.
Lo muthi usetshenziselwa ziphi izimo?
Njengoba kushiwo, ukusetshenziswa okuyinhloko kwe-Methylene Blue ukwelapha i-methemoglobinemia.
Ngakho-ke, iyini i-methemoglobinemia?
Lesi yisimo esihlobene negazi. Kalula nje, uma unalesi sifo, amangqamuzana akho abomvu egazi awakwazi ukuthwala umoya-mpilo ngempumelelo ezicutshini zomzimba wakho.
Uma umzimba untula umoya-mpilo owanele, izindawo ezifana nezindebe zakho, isikhumba, ulimi, nezinzipho zingase zibe luhlaza okwesibhakabhaka. Lokhu kwaziwa ngokuthi i-cyanosis . Ezinsaneni, lokhu ngezinye izikhathi kubizwa ngokuthi 'i-blue baby syndrome'.
Abanye abantu bazuza lesi simo njengefa ngokwezakhi zofuzo. Kodwa-ke, abaningi basithola ngenxa yokusebenzisa imithi ethile, izidakamizwa ezingekho emthethweni, noma ukuchayeka ezintweni ezithile zamakhemikhali .
I-Methemoglobinemia ingaba yisimo esisongela impilo . I-Methylene Blue ingenye yezindlela zokwelapha eziphumelela kakhulu ezitholakalayo.
Lo muthi usebenza kanjani?
I-Methylene Blue ingena egazini lakho bese ibhekana nokusabela kwamakhemikhali okuguqula i-methemoglobin (engakwazi ukuthwala umoya-mpilo) ibe yi-hemoglobin esebenzayo (engakwazi). Cabanga ngayo 'njengokuvuselela' amandla okuthwala umoya-mpilo egazini lakho.
Lo muthi unikezwa esibhedlela noma emtholampilo ngudokotela noma umhlengikazi njenge-IV drip. Inqubo ivame ukuthatha imizuzu emi-5 kuya kwengama-30. Ngokuvamile, umthamo owodwa wanele ukunciphisa izimpawu. Kodwa-ke, uma izimpawu ziqhubeka ngemva kwehora, udokotela wakho angase anqume ukunikeza umthamo owengeziwe.
Imiphumela emibi kanye nokusebenzisana kwezidakamizwa ( imiphumela emibi kanye nokusebenzisana)
Ngaphambi kokunikeza lo muthi, udokotela wakho uzobuyekeza umlando wakho wezokwelapha ogcwele, njengoba ungase ungaphephile kubantu abanezimo ezithile zempilo eziyisisekelo.
| Ukuntuleka kwe-G6PD | Lesi yisifo segazi esibangelwa ufuzo. Uma umuntu onalesi simo ethola i-Methylene Blue, kungabangela ukubhujiswa okusheshayo kwamangqamuzana abomvu egazi (i-hemolysis) , okuholela esimeni esiphuthumayo sezokwelapha. Lokhu kubaluleke kakhulu. |
| Ukukhulelwa noma ukuncelisa | Uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa, kufanele wazise udokotela wakho. |
| Ezinye izimo | Sicela wazise umhlinzeki wakho wezempilo uma unomlando wesifo sezinso noma sesibindi. |
| Ukungezwani komzimba | Tshela udokotela wakho uma une-allergies ku-Methylene Blue noma eminye imithi, ukudla, noma udayi. |
| Ubuthi be-Cyanide | Uma kukhona okusolakala ukuthi kukhona ubuthi be-cyanide, kufanele wazise udokotela wakho ngokushesha. |
Yiziphi imiphumela emibi?
Njengayo yonke imithi, i-Methylene Blue ingabangela imiphumela emibi.
- Imiphumela emibi emincane (ngokuvamile akuyona imbangela yokwethuka):
- Ukushintsha kombala womchamo kanye nendle okuluhlaza okwesibhakabhaka (lokhu kuvamile ngenxa yombala wedayi).
- Isicanucanu nokuhlanza .
- Ukushintsha kombala wesikhumba okuncane.
- Ubuhlungu endaweni yokujova.
- Imiphumela emibi kakhulu edinga usizo lwezokwelapha ngokushesha:
- Ubuhlungu besifuba.
- Isiyezi.
- Ikhanda elibuhlungu.
- Ukudideka.
- Ukujuluka okukhulu.
- Ubuhlungu besisu.
Ukusebenzisana Kwezidakamizwa
Lesi sigaba esibalulekile. Ukuthatha imithi ethile kanye ne-Methylene Blue kungaba nemiphumela eyingozi.
Ikakhulukazi, imithi ethile esetshenziselwa ukucindezeleka noma ukukhathazeka (njenge-SSRIs) ingabangela isimo esisongela ukuphila esibizwa ngokuthi 'i-Serotonin Syndrome' uma ihlanganiswa ne-Methylene Blue.
Lokhu kwenzeka lapho amazinga e-serotonin ebuchosheni bakho eba phezulu kakhulu, okuholela ezimpawini ezifana nokuthuthumela, umkhuhlane ophakeme, kanye nokulahlekelwa ukwazi, okungaba yingozi. Ngenxa yalesi sizathu, kufanele unikeze udokotela wakho uhlu oluphelele lwazo zonke izidakamizwa, amavithamini, kanye nezithasiselo zokudla ozithathayo njengamanje.
Okunye ukusetshenziswa kanye nocwaningo
Nakuba i-FDA iyivumile kuphela i-methemoglobinemia, odokotela ngezinye izikhathi bayisebenzisela izinjongo 'ezingekho ezingeni elifanele' ezimweni ezithile zezokwelapha.
- Ikhambi: Lisetshenziswa njengekhambi lokwelapha ubuthi bamakhemikhali obuvela ezintweni ezifana nama-nitrites. Uma usola ubuthi bamakhemikhali, hamba ngokushesha emnyangweni wezimo eziphuthumayo oseduze.
- Ukushaqeka: Kusetshenziswa ekwelapheni izimo ezinzima zokushaqeka emayunithi okunakekela abagula kakhulu (ICU).
- Ukuhlonza umdlavuza:Kusetshenziswa njengodayi ngesikhathi sokuhlinzwa komdlavuza ukuze kugqanyiswe amangqamuzana omdlavuza kanye nama-lymph node.
- Ucwaningo lwengqondo: Ucwaningo luyaqhubeka ukuze kubonakale ukuthi lungasiza yini ezimweni ezifana ne-Alzheimer's.
- Isibulali-magciwane: Ezinye izifundo zisikisela ukuthi i-Methylene Blue, uma isebenza ngokukhanya, ingasiza ekubhubhiseni amagciwane athile kanye namagciwane.
Okubalulekile: Iningi lalezi zinhlelo zokusebenza lisasesigabeni sokucwaninga. Ungazami ukusebenzisa lesi sidakamizwa ngokusekelwe olwazini olutholakala ku-inthanethi. Landela njalo isiqondiso sikadokotela wakho.
Umlayezo Wokuya Nawe Ekhaya
- I-Methylene Blue iwumuthi okhethekile wesifo segazi esingavamile kodwa esibucayi, i-methemoglobinemia.
- Ungalokothi usebenzise lo muthi wedwa. Kufanele uhlale unikezwa ngemithambo ngaphansi kokuqondisa kukadokotela noma umhlengikazi endaweni yokwelapha.
- Uma unesifo se-G6PD , kubalulekile ukuthi wazise udokotela wakho, ngoba lokhu kubalulekile ekuphepheni kwakho.
- Yazisa udokotela wakho ngayo yonke eminye imithi oyithathayo (ikakhulukazi imithi yokucindezeleka) ukuze ugweme ingozi ye-Serotonin Syndrome.
- Umchamo oluhlaza okwesibhakabhaka uwumphumela ojwayelekile wemithi; ungakhathazeki. Kodwa-ke, funa usizo lwezokwelapha ngokushesha uma uzwa ubuhlungu besifuba noma udidekile.
- Ezinye izindlela ezingase zisetshenziswe ngalo muthi zisasebenza ekuhlolweni. Thembela njalo esilulekweni sikadokotela wakho sezokwelapha.
I-Methylene Blue, i-Methemoglobinemia, i-Cyanosis, ukuntuleka kwe-G6PD, i-Serotonin Syndrome, imiphumela emibi yemithi
