Ingabe izandla nezinyawo zakho zizizwa zingazwakali noma zishisa? Lokhu kungaba yi-Small Fiber Neuropathy!

Wake wazizwa umuzwa wokucasuka ezandleni nasezinyaweni zakho, noma umuzwa oshisayo njengezintuthwane ezihambahamba ezandleni nasezinyaweni zakho? Ungamane nje ulahle lezi zimpawu njengento eyenzeka nje, akunjalo? Ngoba ngezinye izikhathi kungase kube nesimo ngemuva kwalezi zimpawu esidinga ukunakwa. Namuhla, sizokhuluma ngesimo esibizwa ngokuthi i-Small Fiber Neuropathy (SFN) , esenzeka lapho imicu emincane yemizwa emzimbeni wethu yonakele.

Ngakho-ke, iyini i-Small Fiber Neuropathy?

Kalula nje, lesi yisimo sezinzwa esingaphansi kwesigaba se -peripheral neuropathy . Lesi simo senzeka lapho imicu yezinzwa emincane kakhulu esikhumbeni sethu yonakele ngesizathu esithile. Le micu yezinzwa emincane yiyo ethumela izimpawu ebuchosheni mayelana nobuhlungu kanye nokushisa komzimba wethu. Ngakho-ke uma lokhu kulimele, njengoba kushiwo ngaphambili, ukungazweli kanye nobuhlungu obuvuthayo kungenzeka ezandleni nasezinyaweni.

Kodwa-ke, lokhu akuthinti nje izandla nezinyawo kuphela. Kungathinta nezinye izintambo ezincane zemizwa ezilawula imisebenzi ebalulekile emizimbeni yethu, njengomfutho wegazi kanye nokushaya kwenhliziyo .

Lezi zimpawu ze-SFN ngezinye izikhathi zingaba zimbi kakhulu, futhi zingaba nomthelela omkhulu ezingeni lempilo yakho. Nakuba lesi kungesona isimo esibucayi nesisongela impilo, ngezinye izikhathi singaba uphawu lwesinye isimo esibucayi. Yingakho odokotela bezama ukuthola imbangela yalesi simo, baselaphe, futhi banikeze nemithi yokulawula lezi zimpawu ezibuhlungu.

Sivame kangakanani lesi simo?

Eqinisweni, lesi akusona isimo esivamile kakhulu. Ngokusho kocwaningo olulodwa, cishe abantu abangu-53 kubantu abayi-100,000 emhlabeni wonke bane-small fiber neuropathy. Kodwa-ke, abacwaningi bakholelwa ukuthi inani lingaba likhulu kakhulu. Bakholelwa ukuthi akuwona wonke umuntu onalesi simo oxilongwa kahle. Ngakho-ke, mhlawumbe abantu abaningi banale nkinga kunalokho esikucabangayo.

Ziyini izimpawu ze-small fiber neuropathy (SFN)?

Izimpawu zalesi simo zingahluka kumuntu nomuntu. Kodwa-ke, izimpawu zokuqala ezivame kakhulu ubuhlungu "bokubhoboza nezinaliti" noma umuzwa wokushisa ezandleni nasezinyaweni. Lezi zimpawu ngezinye izikhathi ziyafika zidlule, ngezinye izikhathi zihlala njalo, futhi ngokuvamile ziya ziba zimbi kakhulu ngokuhamba kwesikhathi.

Ezinye izimpawu ezingase zibonakale zifaka:

• Ukuzizwa unesiyezi , noma sengathi usuzoquleka.
• Ukuzizwa sengathi inhliziyo yakho ishaya ngokushesha (ukushaya kwenhliziyo) .
• Ukuba ndikindiki .
• Ukungakwazi ukuzwa ubuhlungu, ukushisa, noma ukubanda endaweni encane yomzimba.
• Ukuqaqamba kwesisu , ukungagayi kahle kokudla.
• Ukujuluka kakhulu kunokujwayelekile.

Cabanga ukuthi bekungaba yinto ecasulayo kanjani uma uzizwa sengathi izandla nezinyawo zakho zigwazwa ngezinduku, noma zishiswa umlilo, ngisho noma umi lapho nje.

Kungani sithola i-small fiber neuropathy (SFN)? Ziyini izimbangela?

Ngokumangalisayo, cishe ingxenye yamacala e-neuropathy encane ye-fiber ayenzeka ngaphandle kwesizathu esibonakalayo . Odokotela bakubiza lokhu ngokuthi " i-idiopathic small fiber neuropathy." Lokho kusho ukuthi imbangela eqondile ayitholakali.

Kodwa-ke, ucwaningo luthole ukuthi izifo ezahlukahlukene, ezinye izimo zofuzo, kanye nokuchayeka ezintweni ezithile ezinobuthi nakho kungabangela lokhu.

Lesi simo singabangelwa nayizifo ezithile.

Isifo sikashukela i-Mellitus yisona sifo esiyinhloko nesivame kakhulu esithinta lokhu. Ngaphandle kwalokho, lezi zifo ezilandelayo nazo zingase zibangele i-SFN:

• Inkinga yokusebenzisa utshwala .
• Izifo ezibangelwa ubuthakathaka besimiso somzimba sokuzivikela, isibonelo , isifo se-Celiac , i-Sarcoidosis , noma i-Sjögren's syndrome .
• Ukuphazamiseka kwe-metabolism ye-glucose (Ukungabekezelelani kwe-glucose okuphazamisekile) .
• Ezinye izifo ezithelelanayo, isibonelo i-Hepatitis C noma i-HIV (i-Human Immunodeficiency Virus) .
• I-Metabolic syndrome .
• Isifo se-thyroid .
• I-Sepsis iwukutheleleka okukhulu.
• Ukuntuleka kwevithamini B.

Kungase futhi kube ngenxa yezinye izimo zofuzo.

Ukuguqulwa kwezakhi zofuzo ezizakhi zofuzo ezisiza amangqamuzana ethu ukukhiqiza nokuthumela izimpawu zikagesi ohlelweni lwezinzwa nakho kungabangela i-SFN. Ezinye izifo ezizuzwe njengefa zifaka:

• I-Ehlers-Danlos syndrome
• Isifo sikaFabry
• I-amyloidosis yomndeni
• Isifo sePompe
• I-Porphyria
• Isifo sikaWilson

Eminye imithi kanye nobuthi...

Ingozi yokuba ne-small fiber neuropathy inganda nalapho kusetshenziswa imithi ethile. Izibonelo:

• Amanye ama -antibiotic , isibonelo , i-Metronidazole , i-Nitrofurantoinkanye ne-Linezolid .
• Imithi yokwelapha ngamakhemikhali , njengeBortezomib , iThalidomide , kanye neVincristine (Oncovin) .
• Izithibi ze-tumor necrosis factor , isibonelo , i-etanercept .

Yiziphi izinto ezenza izimpawu zibe zimbi kakhulu? (Izimbangela)

Ngokuvamile, izinto ezingadala lezi zimpawu umoya obandayo oshaya isikhumba , noma indwangu ekhuhla isikhumba . Cabanga nje, uma ulele ebusuku bese amashidi okulala ekhuhla emilenzeni yakho, ubungazizwa ungenamizwa futhi ubuhlungu obungabekezeleleki... Ngisho nento encane njengaleyo ingabangela ubuhlungu obukhulu kulaba bantu.

Yiziphi izinkinga zalesi simo? Ingabe kufanele ngikhathazeke?

I-neuropathy encane ye-fiber inganciphisa ikhono lakho lokuzwa ubuhlungu. Isibonelo, uma uthinta into eshisayo ngengozi, kungenzeka ukuthi ushiswe ungaqapheli. Kungakwenza futhi ube nesiyezi futhi kuthinte ukuhamba kwakho . Ngakho-ke, kungenzeka ukuthi uwe, akunjalo? Ngakho-ke udinga ukuqaphela nalezi zinto.

Udokotela ukuxilonga kanjani lokhu? (Ukuxilongwa)

Udokotela uzoqala ngokukwenza ukuhlolwa ngokomzimba bese ebuza ngomlando wakho wezokwelapha . Akukho ukuhlolwa okukodwa okungahlonza ngokunembile i-small fiber neuropathy. Kodwa-ke, kunezivivinyo eziningana ezivame ukwenziwa:

• I-Electromyography (EMG) : Lokhu kuhlola ukusebenza kukagesi kwezinzwa nemisipha.
• Ukuhlolwa kofuzo : Hlola izimbangela zofuzo.
• Ukuhlolwa kwezithombe : Izinto ezifana ne-CT scans noma i-MRI scans .
• Izifundo zokuqhuba imizwa : Bheka isivinini esihamba ngaso izimpawu ngemizwa.
• I-biopsy yesikhumba - ukuhlolwa kobuningi be-nerve fiber : Kuthathwa isampula encane yesikhumba bese ihlolwa ngaphansi kwe-microscope ukuze kubonakale ukuthi zingaki i-nerve fibers ezikhona.
• Ukuhlolwa kwe-Quantitative Sudomotor Axon Reflex (QSART) : Lokhu kuhlola ukusebenza kwezinzwa ezilawula ukujuluka.

Ngaphezu kwalokho, odokotela bangase bahlole nezinye izimo, njengesifo sikashukela, ezingase zibangele i-neuropathy encane ye-fiber.

Yiziphi izindlela zokwelapha lokhu? Ingabe kungelapheka?

Lapho belapha lesi simo, odokotela bagxila kakhulu ekunciphiseni ubuhlungu obubangelwa yiso.Imithi kanye nezinye izindlela zokwelapha ziyatholakala. I-small fiber neuropathy ivame ukuba yinkinga yesinye isimo, ngakho-ke kubalulekile ukwelapha lesi simo esiyisisekelo .

Imithi yobuhlungu

Kunezinhlobo eziningana zemithi engasetshenziswa ukulawula ubuhlungu:

• Eminye imithi yokuvimbela ukuquleka , njengeGabapentin , iPregabalin , kanye neTopiramate , ingasiza ekunciphiseni ubuhlungu bemizwa.
• Eminye imithi yokucindezeleka , njenge -amitriptyline , i-nortriptyline , kanye ne -desipramine , nayo ilungele ubuhlungu bemizwa.
• Ama-anesthetics angaphandle : Isibonelo , ama-lidocaine creams noma ama-capsaicin creams. Lawa anikeza impumuzo uma efakwa endaweni ebuhlungu.

Khumbula, kubaluleke kakhulu ukusebenzisa imithi njengoba nje udokotela emyalile.

Yini ongayilindela uma uphila nalesi simo?

I-neuropathy encane ye-fiber ikhula kancane kakhulu . Ngezinye izikhathi izimpawu zingase zibe zimbi kakhulu bese zihlala zinjalo iminyaka eminingi. Ucwaningo olulodwa luthole ukuthi phakathi kuka-13% no-36% wabantu abane-neuropathy encane ye-fiber bagcina beba ne-neuropathy enkulu ye-fiber, isimo esithinta i-nerve fiber enkulu . Lokhu kungabangela ukulahlekelwa umuzwa, njengokuzwa ukuthintwa nokudlidliza, njengokungathi ugqoke amagilavu.

Ukubikezela kwakho ngemva kokwelashwa kuncike embangela ye-SFN yakho. Isibonelo, uma unesifo sikashukela, kuzodingeka uthathe imithi yesifo sikashukela impilo yakho yonke. Ngakho-ke, khuluma nodokotela wakho ngesimo sakho nokuthi ukwelashwa kungasiza kanjani ekulawuleni ubuhlungu bakho nezinye izimpawu.

Ingabe lokhu kunomthelela empilweni yokuphila?

Cha, i-small fiber neuropathy ngokwayo ngeke inciphise isikhathi sakho sokuphila . Kodwa-ke, uma kukhona isimo esibangela lokhu, njengesifo sikashukela noma i-HIV, singathinta ukuthi uphila isikhathi esingakanani.

Ngizinakekela kanjani?

Enye yezinto ezibaluleke kakhulu ongazenza ukuze uzinakekele ukuphatha ubuhlungu obubangelwa yi-small fiber neuropathy. Udokotela wakho cishe uzokunikeza imithi yobuhlungu, kodwa ungase ufune nokucabangela izinhlelo zokulawula ubuhlungu . Lokhu kungafaka ukwelulekwa nokwelashwa, ukuzivocavoca, kanye nokubhucungwa noma ukwelashwa ngokomzimba.

Kufanele ngiphinde ngimbone nini udokotela?

Izimpawu ze-neuropathy ezincane ze-fiber zingashintsha futhi zibe zimbi kakhulu ngokuhamba kwesikhathi. Uma une-SFN, tshela udokotela wakho uma ubona izimpawu eziqale engxenyeni eyodwa yomzimba wakho bese zivela kwenye ingxenye. Isibonelo:

• Ukube nje ubuhlungu "obufana nenduku" emilenzeni yami bebungazwakala nasezandleni zami.
• Uma ukuvama kokuhlaselwa ubuhlungu kukhuphukile, noma uma ubuhlungu sebube bukhulu kakhulu.
• Uma kuvele izimpawu ezintsha, njengokuzungeza noma ubunzima bokuhamba.

Kuhle ukubona udokotela ngokushesha ngezikhathi ezinje.

Yimiphi imibuzo ebalulekile okufanele uyibuze udokotela?

Uma uya kudokotela, khumbula ukubuza le mibuzo:

• Iyini imbangela yezimpawu zami?
• Ingabe izimpawu zami zizoba zimbi kakhulu?
• Yiziphi izindlela zokwelapha ezinconywayo kimi?
• Ingabe ngizoba nalesi simo kuze kube phakade?

Ukwazi izimpendulo zale mibuzo kuzokunikeza ukucaca okukhulu.

Ngakho-ke, yini okufanele siyikhumbule kulokhu? (Umyalezo Wokuya Ekhaya)

I-Small fiber neuropathy (SFN) yisimo esingapheli esibangela ukungazweli, ukusha, kanye nobuhlungu ezithweni ezingathinta ikhwalithi yempilo yakho. Ngokuvamile kubonakala njengophawu lwesinye isimo esiyisisekelo, esingaba yingozi.

Odokotela belapha i-SFN ngokuphatha isimo esiyisisekelo. Kukhona futhi ukwelashwa nezinhlelo zokusiza ukuphatha ubuhlungu nezinye izimpawu ezihambisana nakho. Uma uzwa ukungakhululeki noma ukushisa ezandleni nasezinyaweni zakho, ungakushayi indiva bese ubona udokotela. Lezi zimpawu zingaba izimpawu zokuqala zesimo esibucayi. Ungakhathazeki, uma uxilongwa futhi welashwa kusenesikhathi, ngokuvamile ungalawula isimo.

I- Small Fiber Neuropathy, i-SFN, ubuhlungu bemizwa, ukuqaqamba, ukungazweli, isifo sikashukela, i-neuropathy