Ingabe wena noma othile emndenini wakho une -cystic fibrosis? Uma kunjalo, udokotela wakho kungenzeka ukuthi ukunike iphilisi elihlanganisa imithi emibili ebizwa ngokuthi i-Tezacaftor kanye ne-Ivacaftor. Ungayithola ngaphansi kwegama lomkhiqizo i-Symdeko. Lona umuthi okhethekile. Ngakho-ke namuhla, ake sixoxe ngendlela elula kakhulu futhi enobungane ngokuthi lo muthi wenzani ngempela, ukuthi ungawusebenzisa kanjani kahle, ukuthi yiziphi izinto okufanele uziqaphele, nokuthi yimiphi imiphumela emibi engaba khona.
Kwenzekani ngempela ngalo muthi?
Kalula nje, i-cystic fibrosis yisifo esibangelwa ukukhubazeka kwezakhi zofuzo okulawula ibhalansi kasawoti namanzi emizimbeni yethu. Ngenxa yalokho, uketshezi, ikakhulukazi emaphashini nasesimisweni sokugaya ukudla, njenge-mucus, luba lujiyile kakhulu futhi lunamathele. Eqinisweni, lufana ne-glue. Lo mucus ojiyile wenza kube nzima ukuphefumula emaphashini, futhi ungaholela ekuthelelekeni okuvamile .
Cabanga ngakho njengeminyango emincane emaseli omzimba wethu, lapho usawoti namanzi kungena futhi kuphume khona emaseli. Ku-cystic fibrosis, le minyango ayisebenzi kahle.
Yilapho le mithi emibili, iTezacaftor kanye ne-Ivacaftor, ingena khona. Okwenziwa yile mithi ukuthi iya kulawo masango angasebenzi kahle (amaprotheni) futhi iwasize asebenze kahle . Lapho ukunyakaza kukasawoti namanzi kubuyiselwa ngale ndlela, i-mucus ejiyile iyancibilika kancane kancane futhi isuswe kalula emaphashini. Ngemuva kwalokho ukuphefumula kuba lula, futhi izimpawu zilawulwa kakhulu.
Izinto okufanele uzitshele udokotela wakho ngaphambi kokuthatha imithi
Ngaphambi kokuba uqale ukuthatha lo muthi, kubaluleke kakhulu ukutshela udokotela wakho ngesimo sakho sempilo esiphelele. Ngoba kunezimo ezithile ezidinga ukunakekelwa okukhethekile lapho usebenzisa lo muthi. Qiniseka ukuthi ubatshela ngalezi zinto ikakhulukazi.
- Uma unesifo sezinso .
- Uma unesifo sesibindi , lokhu kubaluleke kakhulu, ngoba lo muthi ukhishwa emzimbeni ngesibindi .
- Uma une-allergies ku-Tezacaftor, i-Ivacaftor, noma yimuphi omunye umuthi, ukudla, noma udayi .
- Uma ukhulelwe noma uzama ukukhulelwaAmagama.
- Uma ungumama oncelisayo .
Ngokusekelwe kulolu lwazi, udokotela uzonquma ukuthi lo muthi ukulungele yini noma cha, noma ukuthi umthamo udinga ukushintshwa yini.
Umuthi kufanele usetshenziswe ngendlela efanele.
Ukuze uthole okuningi kulo muthi, kubaluleke kakhulu ukuwuthatha ngendlela efanele.
- Thatha nokudla: Leli philisi kufanele lithathwe nokudla okunamafutha . Isibonelo, amaqanda, ibhotela lamakinati , ushizi, ubisi, iyogathi, noma ukudla okunamafutha amancane kakhukhunathi. Lena yindlela engcono kakhulu yokumunca umuthi.
- Yithathe ngesikhathi esifanayo: Zama ukuphuza umuthi wakho ngesikhathi esifanayo nsuku zonke ngangokunokwenzeka. Shiya cishe amahora ayi-12 phakathi kwemithamo yasekuseni neyakusihlwa.
- Gwinya ithebhulethi lonke: Ungaliphuli, ulichoboze, noma ulihlafune. Gwinya ithebhulethi lonke ngengilazi yamanzi . Ngenxa yokuthi la maphilisi aklanyelwe ukuncibilika kancane emzimbeni, ukuwaphula kungashintsha indlela umuthi osebenza ngayo.
- Ijusi leGrapefruit: Enye into ebaluleke kakhulu ukuthi ungalokothi uthathe lo muthi kanye nejusi legrapefruit. Kungathinta kakhulu ukusebenza kahle komuthi. Futhi, yeka ukudla igrapefruit.
- Ungayeki: Ungayeki ukuthatha umuthi wakho kuze kube yilapho udokotela wakho ekuyala ukuthi uwuthathe. Qhubeka uwuthatha noma ngabe uzizwa ungcono.
Kuthiwani uma ngengozi ngithatha umuthi omningi kakhulu?
Ake sithi uphuze amaphilisi amaningi kakhulu ngephutha. Uma lokhu kwenzeka , iya eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze ngokushesha. Noma shayela i-National Poisons Information Centre e-Colombo National Hospital ukuze uthole iseluleko.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Ake sithi ukhohliwe ukuphuza umuthi wakho ngo-8 ekuseni. Uma ukhumbula cishe ngo-12 emini, okusho ukuthi kusele amahora angaphezu kwayisithupha ngaphambi komthamo wakho olandelayo, thatha umthamo ophuthelwe ngokushesha nje lapho ukhumbula. Kodwa uma kusele amahora angaphansi kwayisithupha ngaphambi komthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa.
Eminye imithi engase ihlangane nalo muthi
Lo muthi ungase uhlangane neminye imithi. Ngakho-ke, kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini, amakhambi, kanye nezithasiselo).
| Uhlobo lomuthi | Izibonelo |
|---|---|
| Gwema ukuthatha lo muthi nalokhu ngokuphelele | |
| Imithi ethile yokuquleka | I-Carbamazepine, i-Phenobarbital, i-Phenytoin |
| Imithi ethile yesifo sofuba | I-Rifampin, i-Rifabutin |
| Isengezo semithi | I-St. John's Wort |
| Isiphuzo | Ijusi le-Grapefruit |
| Yazisa udokotela wakho uma kungenzeka ukuthi lokhu kuthintane. | |
| Ama-antibiotic athile | I-Clarithromycin, i-Erythromycin |
| Imithi yokulwa nesikhunta | I-Fluconazole, i-Itraconazole, ne-Ketoconazole |
| Izithiyo zokucindezela amasosha omzimba | I-Cyclosporine, i-Sirolimus, i-Tacrolimus |
| Umuthi wesifo senhliziyo | I-Digoxin |
Lolu hlu aluphelele, ngakho tshela udokotela wakho ngakho konke okusebenzisayo.
Izinto okufanele uziqaphele lapho uthatha umuthi
Udokotela wakho uzokuqapha njalo ngenkathi uthatha lo muthi.
- Ukuhlolwa okuvamile: Udokotela wakho uzokutshela ukuthi uze emtholampilo ngezinsuku ezihleliwe. Ungaziyeki lezi. Lokhu kubalulekile ukuze ubone ukuthi izimpawu zakho ziyathuthuka noma cha.
- Ukuhlolwa kwegazi: Udokotela wakho cishe uzoyala ukuhlolwa kwegazi okumbalwa ngenkathi uthatha lo muthi. Bazohlola ama-enzyme esibindi sakho, ikakhulukazi ama-enzyme esibindi sakho. Lokhu kuvamile, ngakho ungakhathazeki. Kuwukuqinisekisa ukuthi umuthi uyasebenza kuwe futhi awuthinti isibindi sakho.
- Ukuhlolwa kwamehlo: Ungase ucelwe futhi ukuthi uhlolwe amehlo ngaphambi kokuqala umuthi nangesikhathi uwuthatha. Uma ubona noma yiziphi izinguquko ekuboneni kwakho (njengokubona okufiphele, ukubona indandatho eduze kwezibani) , tshela udokotela wakho ngokushesha.
Yimiphi imiphumela emibi engaba khona?
Njenganoma yimuphi umuthi, lo ungabangela imiphumela emibi. Akuwona wonke umuntu oyitholayo. Kodwa kubalulekile ukuqaphela.
| Uhlobo lomphumela ongemuhle | Izimpawu |
|---|---|
| Imiphumela emibi kakhulu okufanele ibikwe kudokotela wakho ngokushesha | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi noma umphimbo, ubunzima bokuphefumula. |
| Izimpawu zokulimala kwesibindi | Ubuhlungu esiswini esingaphezulu kwesokudla, ukulahlekelwa yisifiso sokudla, isicanucanu, indle enombala okhanyayo, umchamo ophuzi noma onsundu omnyama, ukuphuzi kwamehlo noma isikhumba, kanye nokuzizwa ukhathele ngendlela engavamile. |
| Izinguquko embonweni | Umbono ofiphele, ukubona indandatho ezizungeze izibani, ukulahlekelwa umbono. |
| Imiphumela emibi evame ukungabi mibi kakhulu, kodwa okufanele ibikwe kudokotela uma iqhubeka | |
| Ikhanda elibuhlungu | Ikhanda elijwayelekile. |
| Isiyezi | Isiyezi . |
| Isicanucanu | Ukuzizwa sengathi uzohlanza (Isicanucanu). |
| Ubuhlungu be-sinus | Ukuzwa ubuhlungu noma ukuqina ebusweni noma ebunzini. |
Uma uhlangabezana nanoma yiziphi ezinye izimpawu ezingavamile ezingashiwongo kulolu hlu, sicela wazise udokotela wakho ngazo.
Ungawugcina kanjani umuthi ngokuphephile?
- Gcina kude nezingane: Gcina imithi kude nezingane nezilwane ezifuywayo, endaweni ekhiyiwe.
- Izinga lokushisa elifanele: Gcina ekamelweni lokushisa (phakathi kwama-degree Celsius angu-20 no-25). Vikela ekushiseni okukhulu kanye nomswakama.
- Imithi Ephelelwe Yisikhathi: Ungayisebenzisi imithi esiphelelwe yisikhathi. Yilahle ngendlela efanele.
- Ukulahlwa: Ungalahli imithi engasetshenziswanga endlini yangasese noma uyifake ngqo emgqonyeni kadoti. Buza udokotela wakho ngendlela efanele yokuyilahla.
Umlayezo Wokuya Nawe Ekhaya
- Tezacaftor; Njalo thatha umuthi obizwa ngokuthi i-Ivacaftor kanye nokudla okunamafutha. Lokhu kusiza ukuthi umuthi umunceke kangcono ngumzimba.
- Gwema ukuphuza ijusi le-grapefruit noma i-grapefruit ngokuphelele ngenkathi uthatha lo muthi.
- Qiniseka ukuthi wazisa udokotela wakho ngayo yonke eminye imithi, amavithamini, kanye nemithi yendabuko oyithathayo.
- Uma uphuthelwe umthamo, thatha umthamo ophuthelwe kuphela uma sekudlule amahora angaphezu kwayisithupha ngaphambi komthamo wakho olandelayo. Ngaphandle kwalokho, yeqa. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa.
- Uma uhlangabezana nemiphumela emibi kakhulu, njengokushintsha kombono, ukuphuzi kwesikhumba noma amehlo, xhumana nodokotela wakho ngokushesha.
- Lesi sihloko singesolwazi olujwayelekile kuphela. Landela njalo iseluleko sikadokotela wakho.
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