Ke ʻike ʻoe ua loaʻa iā ʻoe ka maʻi kanesa, nui kou makaʻu a me ka haʻalulu. A laila, ke kamaʻilio nā kauka e pili ana i ka lāʻau lapaʻau, lohe ʻoe i nā lāʻau lapaʻau hou a me nā huaʻōlelo hou āu i maopopo ʻole ai. I kekahi manawa, ke maopopo ʻole iā ʻoe kēia mau mea, piʻi nui aʻe kou makaʻu. He lāʻau lapaʻau ʻokoʻa iki ʻo Avastin i hoʻohana ʻia i ka mālama ʻana i ka maʻi kanesa . No laila i kēia lā, e kamaʻilio kākou e pili ana i kēia lāʻau i kapa ʻia ʻo Avastin (Bevacizumab) ma ke ʻano maʻalahi hiki iā ʻoe ke hoʻomaopopo.
ʻO ka mea mua, e nānā kākou i nā mea hoʻopaʻa Angiogenesis o kēia lāʻau lapaʻau.
No ka hoʻomaopopo ʻana i kēia, e hoʻohana kākou i kahi laʻana maʻalahi. E noʻonoʻo i kahi puʻupuʻu kanesa e like me ka mauʻu ʻino e ulu ana i loko o kā mākou māla. He aha ka mea e pono ai kēia mauʻu e ulu a laha ma loko o ka māla? Pono maoli ia i ka wai. Pēlā nō, pono pū kahi puʻupuʻu kanesa i kahi lako koko e ulu a laha i nā ʻāpana ʻē aʻe o ke kino.
No laila, he maalea loa kēia maʻi kanesa . Hoʻouna ia i kahi "hōʻailona" i ko mākou kino e kiʻi i ke koko e pono ai a hoʻoulu i nā kīʻaha koko hou . E like me kēlā mea kanu mauʻu e ulu ana i kahi ʻōnaehana paipu hou ma lalo o ka honua e lawe mai i ka wai. ʻO nā lāʻau lapaʻau i kapa ʻia ʻo angiogenesis inhibitors e hoʻōki i ka ulu ʻana o kēia mau kīʻaha koko hou. ʻO ia hoʻi, ke ālai nei lākou i nā "kīʻaha koko" e hele ana i ke kanesa. A laila, i ka wā e nalowale ai ke kahe koko, ʻaʻole hiki i ke kanesa ke ulu a laha paha.
No laila pehea e hana ai ʻo Avastin (Bevacizumab)?
He lāʻau lapaʻau ʻo Avastin no ka papa mea hoʻopaʻa Angiogenesis a mākou i kamaʻilio ai ma luna. I ka pololei, he lāʻau lapaʻau kēia i loko o kahi papa kūikawā i kapa ʻia ʻo Monoclonal antibody .
I kēia manawa, ke noʻonoʻo nei paha ʻoe i ke ʻano o ka antibody monoclonal. I ka ʻōlelo maʻalahi, he protein synthetic ia i hana kūikawā ʻia i loko o kahi keʻena hoʻokolohua, e like me nā antibodies a ko mākou kino e hana maoli ai e hakakā i nā maʻi. ʻO ka mea kūikawā e pili ana i kēia, ʻaʻole ia e hoʻopilikia i kēlā me kēia cell i loko o ke kino e like me nā lāʻau chemotherapy maʻamau, akā hoʻopilikia wale i nā cell cancer i kahi lāʻau lapaʻau i kuhikuhi ʻia .
Hoʻoikaika ʻo Avastin i ka VEGF (Vascular Endothelial Growth Factor)ʻO ka molekole. Ua ʻōlelo mua mākou e hoʻouna ana ke kanesa i kahi "hōʻailona" e hana i nā kīʻaha koko hou, a ʻo ia hōʻailona ʻo VEGF. ʻO ka mea a Avastin e hana ai, ʻo ia ke hoʻopili ʻana i kēia molekole VEGF a hoʻōki iā ia mai ka hana ʻana. Ua like ia me ka "pani ʻana" i ka hōʻailona. Ke pau ka hana ʻana o VEGF, ʻaʻole e hana ʻia nā kīʻaha koko hou, a nalowale ka meaʻai o ke kanesa.
Pono anei au i ka chemotherapy inā wau e lawe iā Avastin?
ʻAe, he pilikia kēia no nā kānaka he nui. ʻOiai he lāʻau lapaʻau i kuhikuhi ʻia ʻo Avastin, ʻaʻole ia e hana hoʻokahi . Ua like ia me kahi mea hana keaka kākoʻo. ʻO ka mea hana keaka nui o ka moʻolelo, ʻo ia ka chemotherapy, e pono mau ana.
He ʻano lāʻau lapaʻau ikaika ka Chemotherapy e pepehi ana i nā ʻāpana e māhele wikiwiki ana (e like me nā ʻāpana kanesa). Hana ʻo Avastin ma ke kōkua ʻana i ka chemotherapy.
Akā ʻo ka mea maikaʻi loa, ke hui pū ʻia ʻo Avastin me ka chemotherapy, ʻoi aku ka holomua o nā hopena o ka chemotherapy. ʻO ia hoʻi, ke hui pū ʻia kēia mau lāʻau ʻelua, ʻoi aku ka ikaika o ke kaua ʻana i ka maʻi kanesa. Ma ka hōʻemi ʻana i ke kahe koko i ka puʻupuʻu, pepehi nā lāʻau chemo i nā hunaola kanesa.
He aha nā ʻano maʻi kanesa e mālama ʻia me Avastin?
Ua ʻāpono ʻia ʻo Avastin no nā ʻano maʻi kanesa he nui. Eia naʻe, ʻaʻole ia i hāʻawi ʻia no nā maʻi kanesa āpau. Na kāu kauka e hoʻoholo inā kūpono kēia lāʻau lapaʻau iā ʻoe ma muli o ke ʻano o ka maʻi kanesa āu, kona pae, a me kou olakino holoʻokoʻa.
Hōʻike ka papa ma lalo nei i kekahi o nā ʻano maʻi kanesa maʻamau e hoʻohana ʻia ai ʻo Avastin.
| ʻAno maʻi kanesa | ʻIke koʻikoʻi |
|---|---|
| Ka maʻi ʻaʻai Colon a i ʻole Rectal | Hoʻohana pinepine ʻia ia i nā hihia kahi i pālahalaha ai ke kanesa i nā ʻāpana ʻē aʻe o ke kino (metastatic). Hāʻawi pinepine ʻia me nā lāʻau chemotherapy e like me 5-fluorouracil (5-FU) a i ʻole capecitabine (Xeloda) . |
| Ka maʻi ʻaʻai māmā | Hoʻohana ʻia no kekahi mau ʻano maʻi kanesa māmā holomua. |
| Ka maʻi ʻaʻai puʻupaʻa | Hoʻohana ʻia no ka mālama ʻana i ka metastatic renal cell carcinoma. |
| Ka maʻi ʻōpū | Hoʻohana ʻia ia e like me ka lāʻau lapaʻau no kekahi mau hihia o ke kanesa ovarian. |
| Ka maʻi ʻaʻai o ka ʻōpū | Hoʻohana ʻia no ke kanesa ʻāʻī i hoʻi hou mai a laha paha. |
| ʻO Glioblastoma | He ʻano maʻi ʻaʻai lolo kēia, a hiki ke hāʻawi ʻia kēia lāʻau lapaʻau inā e hoʻi hou mai ana. |
ʻAʻole anei i hāʻawi ʻia ʻo Avastin no ka maʻi ʻaʻai umauma?
ʻOiai ua hoʻohana mua ʻia ʻo Avastin e mālama i ka maʻi ʻaʻai umauma, ua hōʻoia nā noiʻi ma hope mai ua ʻoi aku ka nui o nā pilikia o nā hopena ʻaoʻao ma mua o nā pono o kēia lāʻau. No laila, ʻaʻole ʻae hou nā ʻoihana e like me ka FDA ma ʻAmelika Hui Pū ʻIa i ka hoʻohana ʻana iā Avastin no ka maʻi ʻaʻai umauma.
Hiki iā Avastin ke ho'ōla loa i ka ma'i 'a'ai colon?
ʻAʻole. ʻAʻole ʻo Avastin he lāʻau "kilokilo" e ho'ōla loa i ka maʻi kanesa . Eia nō naʻe, ua hōʻike ʻia nā hoʻokolohua lapaʻau e hiki i kēia lāʻau ke hoʻolōʻihi nui i ke ola o nā maʻi . No ka laʻana, ua ʻike kekahi mau noiʻi ua ola nā maʻi i loaʻa iā Avastin me ka chemotherapy ma kahi o 5 mau mahina ma mua o ka poʻe i loaʻa i ka chemotherapy wale nō. Ua ʻike mākou i ke koʻikoʻi o kēia manawa i kekahi e hakakā nei i ka maʻi kanesa.
He aha nā hopena ʻaoʻao o Avastin?
E like me nā lāʻau lapaʻau ikaika a pau, hiki iā Avastin ke loaʻa nā hopena ʻaoʻao. Eia naʻe, ʻaʻole nā mea a pau e lawe ana iā ia e ʻike i kēia mau hopena ʻaoʻao . Eia nō naʻe, he mea nui loa ia e makaʻala i kēia. E kōkua kēia iā ʻoe e ʻike i nā hōʻailona a hoʻomaopopo koke i kāu kauka.
Aia ma lalo iho kekahi o nā hopena ʻaoʻao koʻikoʻi a maʻamau paha e hiki mai ana.
| Nā hopena ʻaoʻao o Avastin | |
|---|---|
| Ka hopena ʻaoʻao | He aha kāu e ʻike ai e pili ana i kēia |
| Nā hopena ʻaoʻao koʻikoʻi e pono e hōʻike koke ʻia i ke kauka | |
| Ka puka ʻana o ka ʻōpū | He maʻi koʻikoʻi loa kēia. Hiki i nā hōʻailona ke komo pū me ka ʻeha nui o ka ʻōpū, ke kuni, a me ka luaʻi. Pono paha ke ʻoki kino. |
| Ke kahe koko ʻana o loko | Hiki i kēia ke alakaʻi i nā kūlana ola e like me ka hahau ʻana. |
| Hoʻopaneʻe ka ho'ōla ʻana o ka ʻeha | Hoʻomaopopo pono ke kauka i ka hāʻawi ʻana i kēia lāʻau lapaʻau ma mua a ma hope paha o ke ʻoki ʻana. |
| Ka hāʻule ʻana o ka puʻuwai | He kiʻekiʻe loa ka pilikia ke lawe ʻia me nā lāʻau chemo ʻē aʻe e hoʻopilikia ai i ka puʻuwai. |
| Ka pōʻino o nā puʻupaʻa | Hiki ke ʻike ʻia nā hōʻailona e like me ka hoʻonui ʻia o ka protein i loko o ka mimi. |
| Nā hopena ʻaoʻao maʻamau ʻē aʻe (e haʻi i ke kauka) | |
| Ke koko kiʻekiʻe | He mea nui e nānā pinepine i ke koko i ka wā o ka mālama ʻana. |
| Luhi | He hopena ʻaoʻao maʻamau nō hoʻi kēia o ka chemotherapy. |
| Nā ʻūpā koko i loko o nā aa | E makaʻala i nā hōʻailona e like me ka pehu ʻana o ka wāwae a me ka ʻeha. |
| Ka maʻi kahe, ka ʻeha poʻo, ka nalowale o ka makemake, nā ʻeha waha | He mau hopena ʻaoʻao hiki ke hoʻokele pinepine ʻia kēia. |
| Koko i loko o ka mimi | Pono ʻoe e hoʻomaopopo koke i kāu kauka inā ʻike ʻoe i kēia. |
ʻO ka mea nui loa, inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona, mai manaʻo wale, "He mea ʻole kēia." E hoʻomaopopo koke i kāu kauka a i ʻole ke keʻena kūpono o ka haukapila kahi e mālama ʻia ai ʻoe. ʻO ka wikiwiki o kāu hōʻike ʻana, ʻo ka maʻalahi ka mālama ʻana i ke kūlana.
Leka Lawe-Home
- ʻAʻole ʻo Avastin (Bevacizumab) he lāʻau chemotherapy kuʻuna. He lāʻau lapaʻau i kuhikuhi ʻia e hoʻōki i ke kūkulu ʻia ʻana o nā kīʻaha koko e hoʻolako koko i nā hunaola kanesa.
- ʻAʻole hoʻohana wale ʻia kēia lāʻau lapaʻau. Hāʻawi pū ʻia me ka chemotherapy e hoʻonui i kona pono.
- Hoʻohana wale ʻia kēia no nā ʻano maʻi kanesa kikoʻī, e like me ka colon, māmā, puʻupaʻa, a me ka ovarian.
- Ma muli o ka hiki ke loaʻa nā hopena ʻaoʻao koʻikoʻi, he mea nui e hoʻomaopopo koke i kāu kauka i kekahi mau hōʻailona ʻē i ka wā o ka mālama ʻana.
- Inā ua kuhikuhi ʻia ʻo Avastin iā ʻoe a i ʻole kahi mea aloha ma ke ʻano he lāʻau lapaʻau no ka maʻi kanesa, e kamaʻilio e pili ana i kāu kauka i kāu mau nīnau a hopohopo paha . E hiki iā lākou ke hāʻawi iā ʻoe i ka ʻike pololei loa.
Avastin, Bevacizumab, kanesa, mālama ʻana i ke kanesa, chemotherapy, angiogenesis inhibitor, lāʻau lapaʻau kanesa, nā hopena ʻaoʻao, pilika prathikara, anathuru abada, mālama ʻana i ke kanesa sinhala
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