Ua lohe paha ʻoe i ka huaʻōlelo DHT ? Ua lohe paha ʻoe iā ia i ke kamaʻilio ʻana me kahi hoaaloha e pili ana i ka hāʻule ʻana o ka lauoho , a i ʻole e heluhelu ana i kahi ʻatikala e pili ana i ke olakino o nā kāne . He aha maoli ka DHT? He maikaʻi a he maikaʻi ʻole paha no ko mākou kino? He aha ka hana a kēia hormone DHT a kekahi poʻe e makaʻu nei i loko o ko mākou kino? I kēia lā, e kamaʻilio mākou e pili ana i kēia me ka maʻalahi loa, ma ke ʻano hiki iā ʻoe ke hoʻomaopopo.
I ka ʻōlelo maʻalahi, he aha ka DHT?
ʻO Dihydrotestosterone ka inoa piha o DHT. ʻOiai he paʻakikī iki ka inoa, he mea maʻalahi loa ke hoʻomaopopo pehea e hana ai. E noʻonoʻo i nā hormones e like me nā ʻelele liʻiliʻi e hana ana i loko o ko mākou kino. Loaʻa i kēlā me kēia hormone kahi hana kikoʻī.
ʻO DHT kekahi o ia ʻano hormone. I ka pololei, no ka hui o nā hormones i kapa ʻia ʻo androgens ka DHT. ʻO ka hana nui o nā androgens ka hana ʻana a me ka mālama ʻana i nā ʻano kāne.
ʻO ka androgen nui a kaulana loa i loko o ko kākou kino, ʻo ia ka testosterone . Ua lohe paha ʻoe i ia mea. No laila, hoʻololi ko kākou kino i kahi 10% o kēia testosterone i DHT, he androgen ikaika loa. Hana ʻia kēia hoʻololi ʻana ma ka ʻili a puni nā genitals a me ka prostate gland i nā kāne. I nā wahine, hana pū kēia kaʻina hana ma ka ʻili. Eia kekahi, hana pū ia ma nā wahi liʻiliʻi ma nā wahi e like me ko kākou akepaʻa .
Ma muli o ke kiʻekiʻe o nā pae testosterone o nā kāne i loko o ko lākou kino, ʻoi aku ke kiʻekiʻe o ko lākou mau pae DHT ma mua o nā wahine.
He aha ka hana a DHT i ko mākou kino?
Hoʻololi ke kuleana o DHT i nā pae like ʻole o ke ola o ke kāne. He hormone koʻikoʻi ka DHT, ʻoiai i ka wā hāpai a me ka wā ʻōpio.
Akā ma hope o ka wā makua, ʻaʻole i hana nui ʻo DHT i ka mālama ʻana i ka hana kino kāne e like me ka testosterone. I ka wā makua, ʻo DHT ke kumu nui o ka hoʻonui ʻia ʻana o ka prostate a me ka nalowale o ka lauoho kāne.
Ke kuleana o DHT i ka ulu ʻana o kahi pēpē i loko o ka ʻōpū
I ka wā e noho ana kahi pēpē i loko o ka ʻōpū, nui nā hormones e hoʻoholo ai inā he keikikāne a he kaikamahine paha ke pēpē. He mea nui ka hormone i kapa ʻia ʻo DHT no ka ulu pono ʻana o nā ʻāpana kino o waho o ke pēpē keikikāne, ʻo ia hoʻi, ka penis a me ka scrotum. Hana ʻo DHT e like me ka mea kūkulu hale akamai i ke kūkulu ʻana i hale. Kōkua pū ʻo DHT i ka hoʻokumu ʻia ʻana o ka prostate gland .
DHT i ka wā ʻōpio
A laila, ke hiki ke keikikāne i ka wā ʻōpio, hoʻomaka hou ka DHT e hana. ʻO DHT ke kuleana nui no nā loli he nui e hana ʻia ana i ke kino o ke keikikāne.
- ʻUmiʻumi maka a me ka ʻumiʻumi.
- Ka ulu ʻana o ka lauoho ma nā wahi ʻē aʻe o ke kino , e like me ka umauma a me nā ʻāʻī.
- Ka ulu ʻana o ka lauoho mānoanoa ma ka ʻāpana genital .
- Ka ulu hou ʻana o ka ʻōpū prostate .
He mana koʻikoʻi ko DHT ma kēia mau mea a pau.
He aha nā pilikia e hiki ke kū mai inā piʻi aʻe ka pae DHT?
ʻOiai he hormone koʻikoʻi ka DHT ke loaʻa i nā pae maʻamau, hiki iā ia ke hana i nā pilikia olakino like ʻole inā piʻi nui loa. E nānā kākou i kēlā mau mea.
| Kūlana olakino | He wehewehe maʻalahi |
|---|---|
| ʻO ka Benign Prostatic Hyperplasia (BPH) | He maʻi maʻamau i waena o nā kāne ma luna o 50 mau makahiki. Hoʻopuka ka ʻōpū prostate i ka nui o ka DHT, e hoʻonui ai i ka ʻōpū. Hiki i kēia ke pilikia i ka mimi ʻana (mimi pinepine, paʻakikī i ka mimi ʻana). |
| Ka maʻi ʻaʻai prostate | Ua ʻike ʻia nā pae kiʻekiʻe o ka DHT i nā poʻe maʻi me ka maʻi kanesa prostate. Ke hui pū ʻia nā pae kiʻekiʻe o ka DHT me kekahi mau loli genetic, hiki i nā hunaola kanesa ke ulu me ka ʻole o ke kāohi ʻia. |
| Ka nalowale o ka lauoho (Androgenic Alopecia) | ʻO kēia ka mea nui a ka hapa nui o ka poʻe i ʻike ai. He kumu nui ia o ka ʻōhule kāne. Ke piʻi aʻe ka nui o ka DHT, emi nā follicle lauoho ma ke poʻo. Hoʻopōkole ʻia ke ola o ka lauoho, a hāʻule ka lauoho a nāwaliwali nā lauoho hou e ulu ana. |
| ʻO ka maʻi Polycystic Ovarian (PCOS) | He ʻano kūlike ʻole kēia o ka hormonal e hoʻopilikia ai i nā wahine. Loaʻa i nā wahine me PCOS ka nui o nā hormones kāne (androgens) e like me ka testosterone i loko o kā lākou ovaries. Ke piʻi ka pae testosterone, piʻi pū nā pae DHT. Hiki i kēia ke alakaʻi i nā hōʻailona e like me nā pōʻaiapuni menstrual kūpono ʻole, ka ʻākena, a me ka ulu ʻana o ka lauoho kino i makemake ʻole ʻia. |
ʻO ka mea nui, inā e hāʻule ana kou lauoho, ʻaʻole ʻo DHT wale nō ke kumu. Hiki i nā genetics (nā mea i hoʻoili ʻia ma o nā hanauna) a me nā kumu ʻē aʻe he nui ke pāʻani i kahi kuleana.
He aha ka mea e hana ai inā e emi iho nā pae DHT?
He pilikia nā pae kiʻekiʻe a me nā pae haʻahaʻa o ka DHT. Hoʻopilikia nui kēia maʻi i nā kāne. E nānā kākou i nā kūlana olakino e pili ana me ia.
| Kūlana olakino | He wehewehe maʻalahi |
|---|---|
| Ka hemahema o ka 5-alpha reductase | Ua ʻōlelo mua wau ua hana ʻia ka DHT mai ka testosterone e kahi enzyme i kapa ʻia ʻo '5-alpha reductase'. No kekahi poʻe, ma muli o nā kumu genetic, ʻaʻole i hana ʻia kēia enzyme i loko o ke kino a i ʻole ua hana iki ʻia. ʻO ka hopena, lilo nā pae DHT i haʻahaʻa loa. Inā loaʻa i kahi pēpē kāne genetic (XY chromosome) kēia maʻi, ʻaʻole e ulu pono nā ʻāpana genitalia waho. I kekahi manawa, hiki iā lākou ke nānā aku e like me ke kaikamahine i ka nānā mua ʻana. |
| Nā pae testosterone haʻahaʻa (Male Hypogonadism) | He mea maʻalahi loa kēia e hoʻomaopopo. Hana ʻia ka DHT mai Testosterone. No laila, inā haʻahaʻa ka pae testosterone o ke kanaka, e haʻahaʻa nō hoʻi ko lākou pae DHT. Hiki i kēia ke alakaʻi i nā pilikia e like me ka emi ʻana o ka makemake moekolohe a me ka emi ʻana o ka ikaika kino. |
ʻIke hou aku e pili ana i ka hemahema o 5-alpha reductase
He mea paʻakikī iki kēia, no laila e wehewehe iki kākou. Inā loaʻa i kahi pēpē kāne genetically (ʻo ia hoʻi, kekahi me nā chromosomes XY) kēia maʻi, ʻaʻole e ulu nā genitalia waho (penis, testicles) no ka mea ʻaʻole i hana ʻia ka DHT i loko o ka ʻōpū.
Akā, ʻo ka mea kupaianaha, ua ulu aʻe nā testicles o kēia mau keiki i loko o ko lākou kino. Hiki iā lākou ke hana i ka sperm. I ka wā ʻōpio, i ka wā e hana ai ko lākou kino i ka testosterone, e hana ʻia nā mea e like me ka hohonu o ka leo, ka ulu ʻana o nā ʻiʻo, a me kahi penis nui iki. Akā no ka mea ʻaʻohe DHT, ʻaʻole hana ʻia nā mea e like me ka ulu ʻana o ka ʻumiʻumi a me ka lauoho o ke kino.
Pono anei au e ʻike i ke kauka e pili ana i koʻu mau pae DHT?
Inā he kānalua kāu e pili ana i kāu mau pae DHT ma hope o ka heluhelu ʻana i kēia ʻatikala, a inā he mau hōʻailona kēia āu, ʻoi aku ka maikaʻi o ke ʻike ʻana i ke kauka no ka ʻōlelo aʻo .
- No nā kāne: Inā ʻoe e ʻike nei i ka pohō lauoho nui, paʻakikī i ka mimi, a i ʻole ka hana moekolohe.
- No nā wahine: Inā ʻano ʻē loa kou pōʻaiapuni menstrual, inā he ulu lauoho makemake ʻole ʻia ma kou helehelena a i ʻole ke kino, inā he nui kou ʻākena a mau loa (he mau hōʻailona paha kēia o ka PCOS).
- No nā mākua: Inā ʻike ʻoe i kekahi lohi a i ʻole kekahi ʻano ʻē i ka ulu ʻana o ka moekolohe o kāu keiki kāne.
E hoʻomanaʻo, mai hoʻoholo ponoʻī a mālama paha ma muli o ka ʻike i loaʻa ma ka pūnaewele. He paʻakikī loa nā hormones o kou kino. No laila, he mea nui e ʻimi i ka ʻōlelo aʻo a kahi loea lapaʻau kūpono no kekahi hopohopo.
E hana kāu kauka i kekahi mau hoʻāʻo koko e loaʻa ai kahi ʻike pololei o kāu mau pae hormone, inā pono. Inā pono, hiki iā lākou ke kuhikuhi iā ʻoe i kahi endocrinologist .
Leka Lawe-Home
- ʻO DHT (Dihydrotestosterone) kahi hormone kāne ikaika loa i loaʻa mai ka testosterone.
- He mea nui ka DHT no ka ulu ʻana o ke kāne ma ke ʻano moekolohe (i loko o ka ʻōpū a i ka wā ʻōpio).
- Hiki i nā pae kiʻekiʻe o ka DHT ke hoʻoulu i ka hāʻule ʻana o ka lauoho i nā kāne, ka prostate hoʻonui ʻia, a me ka PCOS i nā wahine.
- ʻO ka haʻahaʻa ma mua o ka mea e pono ai o ka DHT hiki ke keakea i ka ulu ʻana o ka moekolohe, ʻoiai hoʻi i nā keikikāne.
- Inā he mau hopohopo kāu e pili ana i kou pae hormone a i ʻole nā hōʻailona pili, e ʻike pono i kāu kauka.
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