Yu go mɔs dɔn yɛri se, "O, da yɔŋ man de bin gɛt blɔd klot wantɛm wantɛm." Ɔ yu dɔn ɛva gɛt yu yon leg we swel wantɛm wantɛm ɛn wund? Tide wi go tɔk bɔt wan sik we dɛn kɔl ‘Thrombophilia’ we kin mek sɔmtɛm tin dɛn lɛk dis. Nɔ fred we yu yɛri dis nem, dis na kɔndishɔn we bɔku pipul dɛn kin gɛt. Na dat mek i rili impɔtant fɔ no bɔt am.
Fɔ tɔk am simpul wan, wetin na Thrombophilia?
Trombophilia na wan sik wae de mek yu blɔd kin klɔt izi wan ɛn kwik pas nɔmal blɔd. Dɔktɔ dɛn kin kɔl dis ‘hypercoagulable’ kɔndishɔn. Dis min se yu blɔd gɛt mɔ pawa fɔ klɔt. Dis kin bi bikɔs ɔf in jɛnɛtiks ɔ i kin gɛt am. Naw imajin wetin kin apin we yu kɔt yu an wit nɛf? Smɔl blɔd kin lɔs, ɛn afta sɔm tɛm blɔd kin klɔt na da say de ɛn di blɔd kin stɔp. Fɔ tru, na sɔntin we de protɛkt wi bɔdi. Afta di wund dɔn wɛl, di bɔdi kin sɔlv di blɔd we dɔn klɔt bak ɛn pul am. Bɔt ɔda tin kin apin to pɔsin we gɛt Thrombophilia. Ivin we di bɔdi nɔ nid am, blɔd kin klɔt na di vein dɛn. Ɔ, di blɔd we kin klɔt nɔ kin sɔlv ɛn pul am fayn. Di big prɔblɛm na we dɛn blɔd ya de travul along di veins ɛn blok wan blɔd vesel we de go to wan impɔtant ɔgan. Na bikɔs ɔl di sɛl dɛn na wi bɔdi kin gɛt di ɔksijɛn we i nid frɔm di blɔd. If wan at blɔk, i nɔ go ebul fɔ kɛr ɔksijɛn. Dis kin mek yu gɛt siriɔs prɔblɛm lɛk
at atak ɛn strok .
Tu men kayn trombofilia de:
As wi bin dɔn tɔk, dɛn kin sheb dis sik to tu men kayn tin bay aw i kin apin. 1.
Acquired Thrombophilia: Dis na di kayn we we dɛn kin gɛt mɔ. I nɔto sɔntin we pɔsin kin gɛt frɔm wi gret gret granpa dɛn. I kin kam bikɔs ɔf sɔm mɛrɛsin dɛn we wi kin tek, di we aw wi de liv wi layf, ɔ ɔda sik dɛn. Di wan we kin bɔku ɛn we kin rili bad pan dɛn kayn tin ya na
Antiphospholipid Syndrome . 2.
Inherited Thrombophilia (Jɛnɛtik/Inherited Thrombophilia): Dis na jɛnɛtik kɔndishɔn we yu kin gɛt frɔm yu mama, papa, ɔ ɔl tu. Prɔtin dɛn de na wi bɔdi we de kɔntrol aw blɔd de klɔt. biכs fכ dεn jεnεtik chenj dεm ya, dεn protin dεm de nכ kin wok fayn. Ɔ di bɔdi kin mek smɔl pan di prɔtin dɛn we kin mek di blɔd nɔ klɔt.
If yu bin dɔn gɛt blɔd bifo yu ol 40 ia, yu dɔn gɛt bɛlɛ bɔku tɛm , ɔ if sɔmbɔdi na yu famili gɛt histri fɔ blɔd, yu kin gɛt dis trombophilia bak we yu gɛt frɔm yu mama ɛn papa.
Wetin na di sɔbtayp dɛm fɔ di trombophilia we dɛn bɔn wit?
Difrεn kayn dεm de fכ dis jεnεtik kכndyushכn. Lɛ wi luk sɔm pan di men kayn dɛn.
| Jɛnɛtik Trombofilia Tayp | Wan simpul ɛksplen bɔt am |
|---|
| Faktɔ V Leiden Trombofilia | Dis na di mכst kכmכn pan di jεnεtik vεryכnt dεm. I kin afɛkt 1% to 5% pan di pipul dɛm. i de mek di risk fכ divεlכp blכd kכlכt na dip vein na di lεg (Dip Vein Thrombosis - DVT) fכ di fכs tεm. |
| Prothrombin Trombofilia we dɛn kɔl | Dis na di sɛkɔn kayn we we pipul dɛn kin gɛt. Di risk de fɔ mek pɔsin gɛt pulmonary embolism, DVT, ɛn fɔ mek i nɔ gɛt bɛlɛ. |
| Protein C we nɔ de wok fayn | Dis na tin we nɔ kin apin smɔl. Risk de fɔ mek blɔd klɔt bak. If na in mama ɛn papa ɔl tu gɛt dis sik, i kin ivin mek i day pan denja. |
| Protein S we nɔ de wok fayn | Dis kin apin bak we nɔ kin apin so ɔltɛm. Wan we we nɔ kin apin so ɔltɛm (we dɛn mama ɛn papa ɔl tu gɛt) kin mek di pikin dɛn we dɛn jɔs bɔn gɛt prɔblɛm wit di blɔd we kin mek dɛn blɔd klɔt we kin mek dɛn layf de pan denja. |
| Antithrombin we nɔ de wok fayn | Dis nɔ kin apin bak (i kin apin pan 1 pan 500 to 5,000 pipul dɛm). Bɔt pipul dɛm wae gɛt dis sik kin gɛt bɔrku risk fɔ gɛt blɔd klɔt pas pipul dɛm wae gɛt ɔda kayn jenɛtik sik. Mɔr pas 80% pan di pipul dɛm wae gɛt dis sik go gɛt at le wan blɔd we dɛn ol 50 ia. |
Wetin na di sayn dɛn we de sho se blɔd dɔn rɔtin?
Bɔrku tɛm, yu nɔr kin ivin no se yu gɛt trombophilia. Di prɔblɛm kin jɔs apin we blɔd klɔt ɛn di sayn dɛn we de sho. Dɛn sayn ya kin difrɛn difrɛn wan bay usay di klot dɔn fɔm.
| Di pat na di bɔdi | Simptom dɛm fɔ ɛkspɛkt |
|---|
| Bren | |
| At | |
| Lɔng | |
| Leg ɔ Arm | - I kin swel wantɛm wantɛm
- I kin fil pen bad bad wan
- Fɔ fil wam we yu tɔch yu
|
| Bɛlɛ | |
Wetin na di tin dɛm wae kin mek pɔrsin gɛt trombophilia?
Apat frɔm di tin dɛn we kin mek pɔsin gɛt jɛnɛtiks, bɔku ɔda tin dɛn ɛn tin dɛn we kin mek pɔsin gɛt dis sik kin mek pɔsin gɛt trombophilia ɔ i kin mek di blɔd klɔt mɔ.
Men rizin dɛn:
- Antifosfolipid Sindrom we pɔsin kin gɛt
- Disseminated Intravascular Coagulation (DIC), we na wan sik we nɔ kin apin na di blɔd we nɔ kin apin so ɔltɛm
- Epataytis we gɛt di sik
- HIV infɛkshɔn
- Liva sik
Tin dɛm wae kin mek di risk bɔku:
- We pɔsin fat pasmak: We pɔsin fat pasmak na big tin we kin mek pɔsin in blɔd klɔt.
- Bεlε: di כmon dεm we de chenj na di bכdi we uman bεlε, na in nכmal fכ mek di blɔd kכlכt.
- Yuz tin dɛn we dɛn kin yuz fɔ smok: We pɔsin smok, i kin pwɛl di blɔd vesel dɛn ɛn i kin mek i izi fɔ mek blɔd klɔt.
- Ɔda sik dɛn: Kɔndishɔn lɛk dayabitis, kansa, at sik, ɛn atrɔsklerɔsis.
- Fɔ de na di sem pozishɔn fɔ lɔng tɛm: We yu de na ɔspitul afta yu dɔn ɔpreshɔn yu, we yu de rayd fɔ lɔng tɛm na plen ɔ bɔs, ɔ we yu sidɔm na wokples, di blɔd we de go na di leg dɛn kin go dɔŋ ɛn blɔd kin klɔt.
- Dɛn de du ɔpreshɔn pan am.
- Fɔ tek bɔn kɔntrol pils ɔ ɔmon riplesmɛnt tɛrapi (HRT) we gɛt di ɔmon ɛstrojen.
- Fɔ gɛt famili histri bɔt blɔd we de klɔt.
- We pɔsin de ol.
- Miskɛri we dɛn nɔ go ebul fɔ fɛn ɛni rizin fɔ.
- Fɔ gɛt pas wan blɔd we de klɔt bifo yu ol 40 ia.
Mɛmba se, jɔs bikɔs yu gɛt wan ɔ mɔ pan dɛn tin ya we kin mek yu gɛt dis sik nɔ min se yu go gɛt blɔd we de klɔt. Bɔt i impɔtant fɔ no bɔt dɛn ɛn fala yu dɔktɔ in advays.
Aw a go no if a gɛt dis sik?
We yu gɛt blɔd we dɔn rɔtin ɛn dɛn de trit yu fɔ am, yu dɔktɔ kin tink se yu gɛt trombofilia. Dɔn dɛn go du sɔm tɛst fɔ kɔnfɔm di kɔndishɔn.
- Yu mɛdikal histri: Dɛn go aks yu bɔt ɛni blɔd we dɔn klɔt bifo, if ɛnibɔdi na yu famili dɔn gɛt am, ɔ if yu dɔn gɛt ɛni bɛlɛ we nɔ gɛt bɛlɛ.
- Fizik Ɛgzam: Dɛn kin chɛk fɔ si if blɔd dɔn swel ɛn pen we yu blɔd dɔn klɔt.
- Blɔd Tɛst: Dɛn kin du spɛshal blɔd tɛst fɔ luk fɔ di jenɛtik kɔndishɔn ɔ ɔda prɔtin we nɔ de we kin mek pɔsin gɛt trombofilia.
- Ɔda tɛst dɛn: Dɛn kin du tɛst dɛn lɛk ɔltra saund skan, CT skan , ɔ angiogram fɔ no usay di blɔd de klɔt di rayt say.
Udat fɔ tek dis tɛst?
Dɛn nɔ kin du dɛn tɛst ya fɔ ɔlman. Yu dɔktɔ kin ɔda fɔ du dɛn tɛst ya pan dɛn tin ya:
- If yu bin gɛt blɔd we bin de klɔt bifo yu ol 50 ia.
- If sɔm pipul dɛn na yu famili gɛt histri bɔt blɔd we dɔn rɔtin.
- If blɔd klɔt fɔm we nɔ gɛt ɛni klia risk factors.
- if bכdi kכlכt fכm na say dεm we nכ sכmtεm (e.g., an, bεlε).
- If yu kin gɛt bɛlɛ ɔltɛm.
- If yu want fɔ no if yu famili de pan denja.
Wetin na di tritmɛnt fɔ trombofilia?
No mɛrɛsin nɔ de fɔ di trombofilia we dɛn bɔn wit. Bɔt dɛn kin ebul fɔ
kɔntrol am fayn fayn wan, ɛn dis kin mek blɔd nɔ klɔt ɛn liv nɔmal layf. Di tritmɛnt we dɛn kin pik kin dipen pan di kayn trombophilia we yu gɛt, if blɔd dɔn fɔm, ɛn aw di sik bad.
- Anticoagulants: Na dɛn wan ya na di men tritmɛnt. Dɛn mɛrɛsin ya de wok bay we dɛn de mek nyu blɔd klɔt nɔ fɔm ɛn bay we dɛn de mek di blɔd we dɔn de gro slo. Heparin ɛn Warfarin na ol mɛrɛsin dɛn. Nyu mɛrɛsin dɛn de naw we izi fɔ tek. Sɔm pipul dɛn kin gɛt fɔ tek dɛn mɛrɛsin ya fɔ di res ɔf dɛn layf.
- Trombolytics: Dɛn kin yuz dɛn tin ya nɔmɔ pan imejensi ɛn siriɔs kes dɛm. Fɔ ɛgzampul, if big blɔd we de na di lɔng dɛn de mek pɔsin in layf de pan denja, dɛn kin gi dɛn mɛrɛsin ya insay di bɛlɛ fɔ mek di blɔd we dɔn klɔt dɔn kwik kwik wan.
- Kɔmpreshɔn Stɔkin: Yu dɔktɔ kin advays yu fɔ wɛr dɛn spɛshal kayn stɔking ya fɔ mek yu nɔ swel ɛn fɔ mek yu blɔd go fayn, mɔ fɔ di wan dɛn we gɛt blɔd na dɛn leg.
- Ɔpreshɔn: Na smɔl tɛm nɔmɔ, if dɛn nɔ ebul fɔ sɔlv big blɔd we dɔn klɔt wit mɛrɛsin, dɛn kin nid fɔ du ɔpreshɔn fɔ pul am.
Tin dɛn we wi kin du fɔ ridyus di prɔblɛm
If yu no se yu gɛt trombophilia, ɔ yu de pan denja fɔ gɛt blɔd klot, i rili impɔtant fɔ chenj yu layf.
- Nɔ smok kpatakpata.
- Mek yu gɛt wɛlbɔdi bɔdi wet.
- Ɛksesaiz ɔltɛm. Ivin sɔntin we simpul lɛk fɔ waka, fayn fɔ du ɛvride.
- We yu de travul fɔ lɔng tɛm: If yu de travul fɔ lɔng tɛm wit plen ɔ bɔs, grap ɛvri ɔ tu awa ɛn waka rawnd smɔl, shek yu leg.
- Afta yu dɔn du di ɔpreshɔn: Grap na bed ɛn bigin fɔ waka jɔs lɛk aw yu dɔktɔ alaw yu fɔ waka.
- Mɛrɛsin we gɛt ɛstrojen: If yu de tek mɛrɛsin we gɛt ɛstrojen, lɛk bɔn kɔntrol pils, tɔk to yu dɔktɔ bɔt dis prɔblɛm. I go ebul fɔ tɛl yu bɔt ɔda we we fayn fɔ yu.
- Dɔktɔ in advays: If yu de tek mɛrɛsin we de mek yu blɔd tan, tek am di rayt tɛm ɛn di rayt doz. Nɔ ɛva stɔp fɔ tek di mɛrɛsin we yu nɔ go to yu dɔktɔ.
Ustɛm fɔ go to di dɔktɔ
If yu gɛt trombophilia, i impɔtant fɔ de kɔntakt yu dɔktɔ ɔltɛm ɛn fɔ du sɔntin kwik kwik wan if ɛni sayn de.
Ustɛm fɔ go to dɔktɔ: Si yu dɔktɔ ɔ
go na di ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU) wantɛm wantɛm. - Nyu swel, pen, ɔ rɛd na yu leg ɔ an.
- Blɔd we nɔ de kɔmɔt fayn, lɛk blɔd we de kɔmɔt na yu nos, blɔd we de na yu urine ɔ stɔl, bikɔs ɔf mɛrɛsin dɛn we de mek blɔd tan.
- If yu gɛt ɛni dawt ɔ kwɛstyɔn bɔt yu sityueshɔn.
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- Wantɛm we yu gɛt siriɔs pen na yu chɛst ɔ i nɔ kin izi fɔ blo (dɛn tin ya kin bi sayn fɔ hat atak ɔ pulmonary embolism).
- Wantɛm we yu ed kin at bad bad wan, i nɔ kin izi fɔ tɔk, ɔ yu kin wik na wan say na di bɔdi (dɛn tin ya kin bi sayn fɔ se yu dɔn gɛt strok).
- Ebi ebi blɔd we de kɔntinyu fɔ kɔmɔt we dɛn kɔt am.
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Mɛsej we dɛn kin kɛr go na os
- Trombophilia na wan sik wae de mek di blɔd kin klɔt izi wan ɛn kwik pas aw i kin bi. Dis kin bi sɔmtin wae de de wae dɛn bɔn am ɔr sɔmtin wae de divɛlɔp leta na layf.
- Bɔrku pipul dɛm wae gɛt dis sik kin liv wae nɔr kin gɛt ɛni blɔd klɔt. Di sayn dɛm kin apin nɔmɔ if blɔd klɔt fɔm insay wan vein ɛn blok blɔd flɔ.
- Blɔd klɔt kin siriɔs if i fɔm na di bren, at, lɔng, ɔr leg, so i impɔtant fɔ no di sayn dɛm.
- Pan ɔl we dɛn nɔ go ebul fɔ mɛn dis sik ɔl, dɛn kin ebul fɔ mɛn am fayn fayn wan ɛn di risk kin ridyus if yu tek mɛrɛsin lɛk aw yu dɔktɔ tɛl yu ɛn fala wɛlbɔdi layf.
Trombofilia, blɔd klɔt, DVT, pulmonary embolism, trombosis, blɔd klɔt, blɔd tinap
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