Yu go mɔs no se Ankylosing Spondylitis (AS) na wan sik we de ɔlsay na yu layf, we kin mek yu nɔ gɛt bɛtɛ trɛnk. Yu no aw i nɔ kin izi fɔ pas di de wit bak pen ɛn mɔnin stiffness. Bɔt, gud nyus de. Pan ɔl we wi nɔ go ebul fɔ mɛn dis sik ɔltogɛda, wi kin kɔntrol di sayn dɛn we i kin gɛt if wi tek di rayt mɛrɛsin, ɛksesaiz, ɛn liv fayn layf. Dɛn mɛrɛsin ya kin ɛp fɔ stɔp ɔr delay fɔ mek yu gɛt bak prɔblɛm.
Step Wan: NSAID - fɔ pen ɛn swel
We yu go to dɔktɔ, dis na di fɔs kayn mɛrɛsin we dɛn go tray fɔ gi yu fɔ dis sik. Wi kin kɔl dɛn Nonsteroidal Anti-inflammatory Drugs, ɔ (NSAID) fɔ shɔt tɛm. Pan ɔl we yu kin bay sɔm pan dɛn tin ya na di kɔwnta na di famasi, sɔm kin nid fɔ gɛt prɛskrishɔn frɔm dɔktɔ.
Fɔ tɔk am simpul wan, dɛn mɛrɛsin ya kin wok bay we dɛn kin stɔp fɔ mek kemikal dɛn we dɛn kɔl prostaglandin na wi bɔdi we kin mek wi bɔdi wam. Dis kin mek yu nɔ fil pen ɛn swel. If yu tek dɛn mɛrɛsin ya na nɛt, mɔ, i kin ɛp yu fɔ slip fayn ɛn nɔ kin mek yu bak nɔ stif na mɔnin.
Di tin we impɔtant pas ɔl na fɔ tek dis mɛrɛsin di tɛm we dɛn gi yu ɛn fɔ di tɛm we yu dɔn tɛl yu lɛk aw yu dɔktɔ tɛl yu . Nɔ stɔp ɔ chenj di doz we yu want.
| Tayp fɔ mɛrɛsin (NSAID) . | Sayd ɛfɛkt dɛn ɛn wetin fɔ no |
|---|---|
| Dis mɛrɛsin kin mek yu bɛlɛ at we yu yuz am fɔ lɔng tɛm. Fɔ ɛgzampul:
So, yu dɔktɔ kin gi yu ɔda mɛrɛsin (lɛk antasid) fɔ protɛkt yu bɛlɛ wit dis mɛrɛsin. If yu gɛt histri bɔt at sik, yu fɔ rili tɛl yu dɔktɔ. Sɔm NSAID kin mek yu gɛt at atak ɔ strok smɔl. |
Step Tu: DMARDs - Anti-Rheumatic Drugs we de modify sik
Sɔntɛnde, NSAID nɔmɔ nɔ kin du fɔ kɔntrol yu sik dɛn. If na so i bi, yu dɔktɔ kin gi yu wan kayn mɛrɛsin we dɛn kɔl (DMARDs) , we tinap fɔ Disease-Modifying Antirheumatic Drugs . Pan ɔl we di nem kin tan lɛk se i kɔmplikt, wetin i de du simpul. I de wok bay we i nɔ de mek yu jɔyn ɛn tisu dɛn nɔ pwɛl bikɔs ɔf inflamɛns. Dɛn tin ya kin mek di sik slo.
| Tayp fɔ mɛrɛsin (DMARD) . | Tin dɛn we yu fɔ no mɔ |
|---|---|
| Sɔlfasalazin we dɛn kɔl | Dɛn kin tek dis as pil. Sɔm pipul dɛn kin gɛt ed we de at, blo, nɔs, ɛn dɛn mɔt kin gɛt wund. Na smɔl tɛm nɔmɔ, bon mɛro kin afɛkt, so bɔku tɛm yu dɔktɔ go chɛk yu blɔd we i de gi yu dis mɛrɛsin. |
| Mɛtɔtreksɛt we dɛn kɔl | Dis kin kam as pil ɔ as injɛkshɔn we yu kin gi yusɛf. Yu go rili nid fɔ tek wan fɔlik asid pil wit dis. Dis na fɔ avɔyd sayd ɛfɛkt lɛk mɔt so ɛn nɔs. Bikɔs dis na smɔl strɔng mɛrɛsin, yu dɔktɔ go chɛk yu blɔd ɛn yu liva fɔ wok ɔltɛm. Dis mɛrɛsin nɔ fayn fɔ uman dɛn we gɛt bɛlɛ ɔ di wan dɛn we de tray fɔ gɛt bɛlɛ. |
Kɔtikosterɔyd - kwik rilif fɔ jɔyn dɛn we de pen
Dis na wan kayn stɛroyd. Yu dכkta kin gi yu wan stεroyd injεkshכn, lεk ``Prednisone'', dairekt insay yu jכint we de rili pen, we swel. Dis go mek yu fil fri kwik kwik wan frɔm di pen ɛn swɛlin.
Bɔt mɛmba se dis nɔto tritmɛnt we dɛn kin gi di wan ol bɔdi. Dɔn bak, dɛn nɔ kin ebul fɔ gi dɛn injɛkshɔn ya ɔltɛm. Bɔku tɛm, di dɔktɔ kin gi dɛn injɛkshɔn ya fɔ sɔm tɛm nɔmɔ insay di ia, ɛn i kin tek sɔm mɔnt.
Biologics - di laytst ɛn pawaful tritmɛnt we
If ɔda tritmɛnt nɔr woke fɔ yu, yu dɔktɔ kin tɛl yu bɔt dis nyu tritmɛnt. Dɛn kɔl dɛn tin ya bayoloji . Dɛn mek dɛn wit sɛl dɛn we gɛt layf. spεshal wan, dεn mεdikeshכn ya de blכk di protin dεm we dεn kכl saytokכn dεm we de mek wi imyun sistεm inflameshn. Dis na tritmɛnt we dɛn kin yuz fɔ mɛn pipul dɛn. Dɛn tin ya kin kam as injɛkshɔn. Sɔm pan dɛn yu kin gi yusɛf na os.
TNF inhibito dεm
Dis na wan kayn bayolojikal we dɛn kin yuz bɔku tɛm fɔ AS. TNF de tinap fכ wan protin we dεn kכl ``Tכmכr Nεkrכsis Fכktכ''. Dɛn mɛrɛsin ya kin trit inflamɛns na di spayna, jɔyn, yay, ɛn intestinal. Dɛn kin slo bak di prɔgrɛs fɔ AS.
- Adalimumab (Humira) we de na di bɔdi.
- Sɛrtolizumab pegol (Cimzia) .
- Etanɛsɛpt (Ɛnbrɛl) .
- Golimumab (Simponi) we de na di bɔdi.
- Infliximab (Rɛmikɛd) .
Intalyukin (IL-17) inhibitɔ dɛn
If TNF inhibitors nɔ de wok, yu dɔktɔ kin stat yu pan dis kayn.
- Ixekizumab (Taltz) we dɛn kɔl Ixekizumab (Taltz) .
- Sekukinumab (Kɔsɛntiks) .
Bayolojikal na mɛrɛsin dɛn we rili pawaful. Na dat mek dɛn gɛt sayd ɛfɛkt fɔ no bɔt. Yu dɔktɔ go ɛksplen ɔl dis to yu bifo yu bigin fɔ trit yu.
| Men risk ɛn sayd ɛfɛkt dɛm fɔ biologics | |
|---|---|
| Risk fɔ gɛt di sik | Bikɔs dɛn mɛrɛsin ya de stɔp di imyun sistɛm te to sɔm mak, dɛn kin mek di risk fɔ gɛt infɛkshɔn, mɔ di TB (TB). So, i impɔtant fɔ mek dɛn du tɛst fɔ TB bifo yu bigin fɔ tek dɛn mɛrɛsin ya. |
| Ɔda prɔblɛm dɛn we kin apin | - Na rili smɔl inkris pan di risk fɔ gɛt kansa na di skin. - Di risk fɔ gɛt limfoma kansa pan pikin dɛn go bɔku. - If yu dɔn ɔlrɛdi gɛt inflammatory bowel disease (IBD), yu sik kin wɔs. |
If yu nɔr fil fayn afta lɛk 3 mɔnt pan dis tritmɛnt, yu dɔktɔ go disayd fɔ stɔp di mɛrɛsin ɔr chenj yu to ɔda biyolojikal.
Op fɔ di tritmɛnt dɛn we wi go gɛt tumara bambay
Sayɛnsman dɛn de wok naw fɔ fɛn nyu mɛrɛsin dɛn we go ebul fɔ rivɛns AS. Dɛn de stɔdi bak aw wi jin dɛn kin afɛkt di sik. Dis risach kin mek yu gɛt mɔ tritmɛnt dɛn we go wok fɔ yu tumara bambay.
Mɛsej we dɛn kin kɛr go na os
- Ankylosing Spondylitis (AS) na wan sik wae de kam wae yu de liv yu layf, bɔt yu kin kɔntrol am fayn fayn wan wit di rayt tritmɛnt ɛn layf stayl.
- Bɔku tɛm, di tritmɛnt kin bigin wit NSAID. If dɛn tin ya nɔr de kɔntrol di sik, dɛn kin yuz mɛrɛsin lɛk DMARD ɔr biologics.
- Trust yu dɔktɔ. Fɔ fala in instrɔkshɔn dɛn di rayt we. Go na klinik dɛn di rayt tɛm ɛn du tɛst.
- Nɔ ɛva stɔp fɔ tek yu mɛrɛsin ɔ chenj di doz fɔ yusɛf. If yu gɛt ɛnitin we de mɔna yu, tɔk to yu dɔktɔ.
- Apat frɔm mɛrɛsin, fɔ du ɛksɛsayz fayn ɛn it fayn fayn it na tu impɔtant tin fɔ kɔntrol dis sik.
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