Polatuzumab Vedotin (Polivy) hmanga enkawl i ni em? Hemi chungchang hi awlsam takin han sawi ila

I doctor-in nangmah emaw i hmangaih tu emaw lymphoma a vei tih a hrilh hian, enkawl dan tur hriat duh leh hlauhthawn deuh hi thil pangngai a ni. A bik takin Polatuzumab Vedotin ang damdawi thar, specialized tak chungchang i hriat hian eng nge a nih, engtin nge a thawh tih, leh a side effects a awm em tih zawhna tam tak i nei mai thei Chuvangin lungngai suh. Vawiin hian Polatuzumab Vedotin (brand name Polivy tia hriat fo) vaccine chungchang hi thu awlsam leh chiang takin kan sawi dawn a ni.

Polatuzumab Vedotin hi eng nge ni?

A awlsam zawngin sawi ila, hei hi cancer cell tihhlumna atana pek dan bik a ni. Targeted Therapy kan ti a. Chemotherapy pangngai ang lo takin he damdawi hi a fing hle. "Smart missile" ang mai a ni. He damdawi hi chi hnih atanga siam a ni a: 1. Monoclonal antibody: Hei hi "navigator" a ni. Taksa pumpuiah a fang kual a, cancer cell (a bik takin `Diffuse Large B-cell Lymphoma` an tih chi khat) a hmu a, an chunglama protein bik pakhatah a inzawm tlat a ni. 2. Chemotherapy damdawi: Hei hi "missile" chhunga bomb awm chu a ni. Monoclonal antibody hian cancer cell a hmuh a, a inzawm hnuah he chemo damdawi hi cancer cell-ah direct-in a kal a, a tichhia a ni. Hetiang tih dan avang hian cell hrisel tak takte chhiatna chu chemotherapy pangngai aiin a tlem zawk a ni. Chu chu he thila thil danglam bik chu a ni.

Enkawlna i tan hmaa i doctor hnena i hrilh tur thilte

He enkawlna hi i tan a tha em tih leh a him em tih ngaihtuah tur chuan rinawm takin i hriselna chanchin i doctor hnenah hrilh a pawimawh hle . I sawihonaah hian a hnuaia mite hi telh ngei ang che:

• Tuna Hri kai mek : Viral infection chickenpox , herpes, emaw infectious condition dang i neih chuan.
• Liver natna : Liver nena inzawm natna i neih chuan.
• Thisen lama harsatna: Thisen test-ah thisen var, thisen sen, platelet a tlem tih hmuhchhuah a nih chuan.
• Nerve disorder: I taksa peng hrang hrangah rilru hahna, tingling emaw, nerve kaihhnawih harsatna dang emaw i neih chuan.
• Allergies : He damdawi hi allergy (allergy) i neih chuan, damdawi dang, ei tur, dye dang eng pawh.
• Naupai: Naupai, nau pai tum emaw, naupai nia rinhlelh emaw i nih chuan.
• Nau hnute pek : Nu i nih chuan nausen hnute pe mek i nih chuan.

Engtin nge he damdawi hi pek a nih a, a dose pakhat a tlakchham chuan engtin nge ni ang?

He damdawi hi saline ang maia vein-a infusion angin pek a ni. Damdawi in emaw, clinic emaw-ah pek a ni a, chu chu doctor emaw nurse emaw ang chi, mi thiam thiam (trained professional) enkawlna hnuaiah pek a ni. Chuvangin in lama hruai emaw, nangmah ngeiin inject emaw a ngai lo.

He damdawi hi damdawi in pakhata medical staff te enkawlna hnuaia pek a nih avangin overdose chance a tlem hle. Hei hi i rinhlelh chuan i doctor emaw nurse emaw hnenah hrilh nghal rawh.

Damdawi inah inenkawl tura kal hun ruat saah i kal thei lo a nih chuan lungngai suh, a rang thei ang bera doctor ko mai rawh. A hnua i tih tur chu a hrilh ang che.

Enkawl laia i hriat tur thilte

Hemi hun chhung hian i taksa hi tlem tal ngaihven a pawimawh.

Damdawi lam enfiah fo thin

He damdawi i ei lai hian i doctor chuan i thisen cell (red cells, white cells, platelets) leh liver function enfiah nan thisen test a ti fo thin. Heng test te hi skip suh.

Hri kai laka invenna

He damdawi hian i taksain natna a do theihna (immunity) chu tlem a ti tlem thei a ni. Chuvangin:

• Mipui tamna hmun a theih ang tawkin pumpelh rawh.
• Khawsik leh khawsik ang chi natna nei te lakah inthiarfihlim rawh .
• Khawsik, khawsik, rilru na, khuh ang chi symptoms i neih chuan mahni invenna nei suh la, i doctor ko nghal rawh.

Thisen chhuah theihna a awm

He damdawi hian thisen zam tura puitu platelet a tihtlem thei a ni. Chuvangin, hliam danglam tak tak, vun hnuaia hmun sen te te, bawlhhlawh dum emaw, zun chhunga thisen awm emaw i hmuh chuan doctor hnenah hrilh nghal rawh.

Vaukhânna pawimawh tak: thluak natna

A tlem berah chuan damlo thenkhat chuan thluak tichhe thei natna khirh tak (Progressive Multifocal Leukoencephalopathy - PML) an nei thei. Hei hi dinhmun pawi tak a ni. A hnuaia symptoms te hi fimkhur hle ang che.

Nangmah emaw, i enkawltu tu emaw hian heng chhinchhiahnate hi a neih chuan damdawi lam pan nghal rawh: * Mit a inthlak danglam * Ngaihtuah harsa, buaina * Midang thusawi sawi leh hriatthiam harsa * Kea kal harsa, inthlauhna hloh * Taksa sir khata chak lohna

Naupai leh Naupai theihna

Hei hi a pawimawh hle.

• Hmeichhia: He damdawi ei lai leh enkawlna chawlhsan atanga thla 3 chhung chu naupai kim loh tur.
• Mipa: He damdawi hi i ei lai leh enkawlna i chawlhsan hnu thla 5 chhung fa neih loh tur.
• Nau hnute pek: Enkawl lai leh chawlhsan hnu thla 2 chhung chu hnute pek loh tur a ni.

He damdawi hian nausen piang lo chu nasa takin a tichhe thei a ni. Hmeichhia leh mipa nau neihna a nghawng thei bawk. Hemi chungchangah hian ngaihtuahna i neih chuan i doctor nen inbia ang che.

Side effect awm thei te chu engte nge ni?

Damdawi dang ang bawkin he damdawi hian side effect a nei thei a ni. Mahse, mi zawng zawngin an hmu vek lo. A hnuaia tarlan te hi a side effects awm tam ber berte an ni.

Polatuzumab Vedotin Side Effects i doctor hnenah report nghal tur Side effects chu a awm reng emaw, a buaithlak emaw a nih chuan doctor hnenah report tur a ni

Allergy natna a awm thei	Skin rash, itching, hmui/lei/hmai a hring.
Nerve lama harsatna a awm	Kut leh kea natna, rilru hahna, emaw tingling (Peripheral Neuropathy).
Hri kai theihna chhinchhiahna	Khawsik, khawsik, ril na, khuh, zun kawng infection.
Liver hliam chhinchhiahna	Zun dum dum, mit/vun sen, pum dinglam chunglam na, luak chhuak.
Thisen tlahniam chhinchhiahna	A tlangpui aia chau zawka inhria, vun rawng, thawk harsatna, emaw, hliam emaw, thisen chhuah awlsam emaw.
Symptom na tak dang a awm bawk	Luak chhuak, luak chhuak, luak chhuak, hmuh harsa, tawng harsa, kal harsa.
Ei duhna a tlahniam	Ei duhna a tlahniam.
Joint natna	Joint natna.
Rihna tihtlem	Thawhrimna tel lovin taksa rihna tihtlem.

Take-Home Thuchah a ni

• Polatuzumab Vedotin hi lymphoma cancer enkawlna atana hmanraw bik, targeted therapy a ni. Cancer cell direct-a target-in hna a thawk a ni.
• Enkawlna i tan hmain i hriselna chungchang leh damdawi i ei zawng zawngte chu i doctor hnenah i hrilh hmasa phawt a pawimawh hle.
• Enkawl lai hian natna lan chhuahna pawi tak tak, khawsik, thisen chhuah, rilru hahna, emaw, tawng/kal harsatna emaw a awm chuan doctor rawn nghal tur a ni.
• Naupai leh hnute pek chungchanga doctor thupek kha khauh takin zawm rawh.
• Zawhna emaw, ngaihtuahna emaw i neih apiang chu i doctor nen zalen takin sawipui rawh. He indonaah hian nangmah chauh i ni lo.