I fate hian he cancer hmuh tur awm lo tak hi a nei em? Rhabdoid Tumor chungchang hi han sawi ila!

Moms and dads, in thinlungah phurrit lian tak a ni a, in naupangin cancer a vei tih a hriat hunah pawh ngaihtuah duh loh thil a ni. Mahse a chang chuan naupangte hian kan beisei loh natna an nei thei a. Vawiin hian cancer chi khat, a tlem hle, a darh chak em em, naupang, a bik takin naupang tê tête tuar thei chungchang kan sawi dawn a ni. Hei hi Rhabdoid Tumor an ti a . He hming i hriat hian mak i ti deuh mai thei, mahse awlsam takin i sawifiah ang u.

Rhabdoid Tumor tih hi eng nge ni? A awlsam zawngin...

Rhabdoid Tumor hi cancer chi khat, a lo thang chak hle a ni . Naupang te leh nausen te ah a tam ber . Microscope hmanga en chuan heng cancer cell te hi rhabdomyoblasts , taksa ruh siamtu cell chi khat nen an inang hle. Chuvangin "rhabdoid" an ti a ni. He cancer hi naupang kal (kidney), soft tissue emaw, central nervous system (brain leh spinal cord) ah te a lo awm thei a ni. Vanduaithlak takin he cancer hi a darh chak hle a, enkawl a harsa hle.

Rhabdoid Tumor chi hrang hrang a awm em?

Ni e, he cancer hi a awmna hmun a zirin chi hrang hrang a awm a. Eng nge an nih i en ang u.

1. Kal chhunga natna hrik (Rhabdoid Tumor) (RTK) .

Hei hi naupang kal (kidney) a rhabdoid tumor a ni. A chang chuan ``(RTK)`` tia tawifel a ni.

2. Extracranial emaw Extrarenal emawa Malignant Rhabdoid Tumor awm thei

Hetiang cancer chi hi naupang soft tissue leh taksa peng dang, thin, lung leh vun-ah te a lo awm thei a ni. Malignant rhabdoid tumors (MRT) an ti bawk. "Malignant" tih awmzia chu cancer vei tihna a ni.

3. Atypical Teratoid Rhabdoid Tumors (ATRT) te hi a awm thei lo.

Hetiang rhabdoid cancer hi naupang central nervous system, thluak leh ruhroah a lo awm thin. Hetiang cancer chi ah hian cancer cell te hi naupang thluak emaw, ruhro emaw ah an lo piang hmasa ber thin. Heng (ATRT) cancer zinga 50% vel hi cerebellum (cheve leh balance control tu) emaw brainstem ( thawk leh heart rate ang chi thil control tu) ah a lo awm thin.

Tute nge Rhabdoid Tumors vei tam ber?

Nausen leh naupang te tak te a nghawng ber a , a bik takin thla 11 leh thla 18 inkar te a nghawng nasa hle . Puitlingte hian he natna hi an vei tlem hle.

Hei hi a tlem em em a, zirchianna thenkhat chuan mi maktaduai khat zinga pakhat aia tlem lovah a thleng niin an sawi.He cancer hi a tlem hle niin an sawi. Chumi awmzia chu thil awm lo tak a ni tihna a ni.

Engvangin nge heng rhabdoid tumor te hi an lo awm? Eng nge a chhan?

A tam zawkah chuan rhabdoid cancer thlentu ber chu SMARCB1 gene-a genetic mutation vang a ni. Kan taksaah hian cell te than dan thunun thei tur vengtu tlemte a awm tih han ngaihtuah teh. He SMARCB1 gene hi tumor suppressor gene a ni a . Cell thanna control tu protein a siam chhuak thin. Traffic cop ang maiin cell-te chu rang lutuka inthen darh turin a titawp a ni. Chuvangin, he SMARCB1 gene-ah hian chhiatna, chu chu mutation a awm a nih chuan, chu control chu a bo a , cell-te chu an inthen rang lutuk a, cancer a thlen a ni . A tlem berah chuan heng cancer te hi tumor suppressor gene dang SMARCA4 tih a mutation vang pawh a lo awm thei bawk. Naupang thenkhat chuan he mutated gene hi an nu leh pate hnen atangin rochun thei mahse, a tam zawkah chuan heng cancer te hi chhungkaw history nei lo genetic mutation thar lo awm vang a ni Chumi awmzia chu chhungkuaa tu mahin he mutation hi an nei lo a nih pawhin naupang cell-te hian he mutation hi an nei ve mai thei tihna a ni. Naupang enkawl lai hian he gene mutation hi zawng turin genetic evaluation neih theih a ni.

Rhabdoid Tumor natna lan chhuah dan chu engte nge ni?

Naupang kum leh cancer awmna hmun a zirin symptoms a inang lo thei . A lan chhuah dan chu cancer lo chhuahna hmunah a intan tlangpui. Chung zingah chuan nerve tihchhiat, thawk harsa, naupang pum chhunga lump awm te pawh a tel thei. He cancer hi a darh chak em avangin a symptoms a lang nghal vat thei a ni. A lan chhuah dan dangte chu:

• Khawsik fo thin.
• Lu na .
• Thisen chu zun ( Hematuria ) ah a awm .
• Nausea leh luak chhuak .
• Lymph node a lo hring chhuak .
• Thinrim reng, rilru hahdam lo (Irritability).
• Chaw ei chu a thlum lo .
• Mutthilh lohna danglam tak.
• Nausen ah chuan a lu a lian deuh deuh thin.
• Balance hloh emaw, kal harsa emaw.

I fain heng symptoms pakhat emaw a aia tam emaw a neih chuan doctor lam pan vat a pawimawh hle.

Engtin?Engtin nge he Rhabdoid Tumor hi an hriat theih?

I fa enfiahtu doctor chuan taksa enfiahna a nei hmasa ang a, i fa natna lan chhuah dan a zawt hmasa ang che. Hemi hnu hian test eng emaw zat an order ang a, an natna hmuhchhuah chu an finfiah ang. Chûng zîngah chuan:

• Ultrasound scan: Hei hian chakna sang tak nei sound wave hmangin naute chhungril taksa peng hrang hrang thlalak (sonogram) a siam a.
• CT scan: Hei hian X-ray leh computer hmangin naupang soft tissue leh ruh te chu three-dimensional (3D) image a siam a.
• MRI scan: Hei hian magnet, radio wave leh computer hmangin naupang thluak leh ruhro ang chi hmun chipchiar taka thlalak a siam a.
• Neurological exam: Hei hian naupang thluak, ruhro leh nerve hnathawh dan a test thin.
• Lumbar puncture / Spinal tap: Hemiah hian naupang ruh (spinal cord) atanga cerebrospinal fluid (CSF) sample lak a ni a, microscope hmangin cancer cell a awm leh awm loh enfiah a ni.

Mahse, heng scan-ah hian cancer chi dang ang chi rhabdoid tumor a lang thei a ni. Chuvangin Doctor-te chuan tissue sample an la fo a, test belh leh turin thupek an pe fo thin. Heng test hrang hrangte hi:

• Genetic testing: Naupang thisen emaw tissue emaw sample lak a ni a, gene `SMARCB1` leh `SMARCA4`-a mutation awm leh awm loh enfiah a ni.
• Biopsy: Hetiang tih danah hian doctor chuan needle hmangin tumor sample te tak te a la thin. Chumi hnuah pathologist chuan microscope hmangin cancer cell a awm em tih a en a. Cancer cell hmuhchhuah a nih chuan a tam thei ang ber tumor chu operation neih chhung emaw, a hnua surgery neih hunah emaw lakchhuah theih a ni.
• Immunohistochemistry: Hei hi test chiang tak a ni. I fa tissue sample pakhata marker/antigen thenkhat zawng turin antibodies a hmang thin. Heng marker te hian rhabdoid cancer nge cancer chi dang a nih leh nih loh hriat theih nan a pui thei a ni.

Rhabdoid Tumor hi engtin nge enkawl a nih?

Naupang enkawlna kawngah hian naupang oncologist chuan hma a hruai thin. Specialist dang team nen thawkdunin naupang tana tha ber tur enkawlna ruahmanna an siam thin. Rabdoid cancer enkawlna atan hian enkawlna hrang hrang engemaw zat hman dun theih a ni. He cancer hi a darh chak em avangin zirchianna hrang hrangah chuan enkawlna tam tak hman dun chuan cancer cell pakhat chauh hman ai chuan a that zawk tih hmuhchhuah a ni.

• Surgery: Biopsy-in cancer a paih chhuah loh chuan a hmasa ber chu, a theih chuan, a tam thei ang ber, a zawng zawng pawh ni thei, paih chhuah theihna tur surgery tih hi a ni.
• Chemotherapy (Chemo): Hei hian cancer cell thang zel tur titawp turin damdawi pek a ni. Heng damdawi te hian cancer cell thenkhat an that a, thenkhat chu an inthen darh thei lo. Mahse, heng damdawi te hian cell tha leh cancer cell inthlauhna an hre thei lo va, chuvangin side effect a thlen thei a ni.
• Stem cell transplant hmanga chemotherapy dose sang: Chemotherapy dose sang hian cancer cell tam zawk a that thei. Mahse, cell hrisel tak tak, ruhro chhunga thisen siamtu cell te pawh a that bawk. Hei hi chinfel nan naupang ruhro thenkhat chu lak a, chemotherapy dose sang tak pek hmain dahkhawm a ni. Enkawl zawhah ruhro chu naupang hnenah pek let lehin, a cell chhe tawhte chu a thlak leh thin.
• Radiation therapy: Hei hian high-energy X-ray hmangin cancer cell te chu a ti tlem emaw, a tichhia emaw a ni. Mahse, radiation therapy hian naupang thanlenna leh thluak than dan a nghawng theih avangin naupang kum leh a lian leh te a zirin a dose hi siamrem a ni.
• Clinical trials: Doctor chuan i fa cancer enkawlna atan clinical trial thar (chemotherapy chi thar, targeted therapy, emaw immunotherapy drugs) neih a rawt thei bawk.

Enkawlna avanga nghawng tha lo awm thei te chu engte nge ni?

Cancer enkawlna, a bik takin chemotherapy hian side effect a thlen thei a ni. Hei hi a chhan chu cancer cell thah nana damdawi hman te hian cell hrisel te pawh a that vang a ni. Mahse, a side effect tam zawk chu enkawlna tihtawp a nih hnuah a bo vek . I fa medical team te nen hian heng side effects te hi i enkawl thei ang. Side effects tlangpui chu:

• Sam tlakchham `(Alopecia)` .
• Chaw chu a thlum lo.
• Ek khal.
• Kawthalo.
• Nausea leh luak chhuak.
• Kawng leh hmuiah hliam.
• A hring chhuak `(Edema)` .
• Mu thei lo.
• Chauh lutuk .
• Memory lama harsatna a awm.

Rhabdoid Tumors hi ven theih a ni em?

Vanduaithlak takin heng cancer te hi genetic mutations avanga lo awm a nih avangin ven theih a ni lo . Mahse, i chhungkuaa mi tu emaw chuan rhabdoid cancer emaw, cancer dang emaw a vei tawh a, fa i beisei a nih chuan, i doctor nen genetic counseling chungchang sawipui a tha ang Genetic counseling hian i fate zingah genetic condition i neih theihna tur i hriatthiam theih nan a pui thei che a ni.

Rhabdoid Tumor hi tihdam theih a ni em? Naupang hmalam hun chu eng ang nge ni ang?

I fa enkawltu doctor chuan he zawhna chhanna dik tak hi a pe thei che a ni. Engpawhnise,Vanduaithlak takin naupang malignant rhabdoid tumor nei tam zawk hi kum engemaw zat aia rei an dam lo. Mahse, naupang chu kum 2 a tlin hnua hmuhchhuah a nih chuan a prognosis chu a tha deuh thei. He cancer damchhuahna rate hi thil engemaw zatah a innghat a ni:

• Naupang kum zat.
• Naupang taksa chhunga cancer awmna hmun.
• Cancer hian taksa peng dangah a darh tawh em tih.
• Cancer engzat nge operation hmanga lakchhuah a nih.
• Naupangin cancer enkawlna a dawn dan tur.

Malignant rhabdoid carcinoma hi a tlem em em avangin dam rei zawng statistics hi damlo tlemte chauh atanga chhut a ni. Chuvangin naupang dam rei zawng tak tak chu a inang lo thei hle. Zirna hrang hrangah chuan rhabdoid carcinoma of the kidney (RTK) vei kum nga chhunga dam rei zawng chu 20% leh 25% inkar a ni tih a tarlang. Hei hian RTK vei hmuhchhuah zinga 20% leh 25% inkar chu an hmuhchhuah atanga kum nga hnuah pawh an la dam tihna a ni. Atypical teratoid rhabdoid carcinoma (ATRT) vei kum nga chhunga dam rei zawng chu 32% leh 50% inkar a ni.

Hetiang thil i hriat hian phurrit lian tak leh lungngaihna i neih hi thil pangngai tak a ni. Mahse, nangmah chauh i ni lo tih hre reng ang che.

Doctor hnenah eng nge ka zawh ang?

I fain cancer a vei tih i hriat hunah zawhna tam tak neih hi thil pangngai a ni. Chutih laia zawh tur hriat reng tur zawhna thenkhat chu hetiang hi a ni:

• Ka fa hian eng ang cancer nge a neih?
• Ka fa cancer hi eng stage nge ni?
• Ka fa hian eng test nge a neih ang?
• Ka fa cancer enkawl dan tur chu engte nge ni?
• He enkawlna hi hlawhtlinna chance engzat nge awm?
• Ka fa hian eng clinical trial-ah nge a tel theih ang?
• Engtin nge enkawlna a hlawhtling em tih kan hriat theih ang?

Enkawl lai leh enkawl hnuah engtin nge follow-up an tih thin?

I fa cancer enkawlna chhung zawng hian natna hriat theihna atana hman test thenkhat chu tih nawn leh a ngai dawn a ni. Heng test te hi enkawlnain a thawh that dan tehna atan hman a ni. Heng test result a\ang hian i medical team te chuan i thawhpui ang a, eng step nge i tih tur tih an rel ang. Hei hian enkawlna chhunzawm emaw, thlak danglam emaw, tihtawp emaw a huam thei a ni. I fain cancer enkawlna a zawh hnuah, a hun hunah follow-up exam leh test neihpui turin a rawn kir leh a ngai dawn a ni . Heng follow-up neih chhung hian i doctor chuan i fa dinhmun a lo tha tawh em tih emaw, natna a lo let leh tawh em tih emaw a enfiah ang. He follow-up hi enkawl hnuah kum engemaw zat a awm thei.

A tawp berah chuan hre reng ang che... (Take-Home Message)

I fain cancer a vei tih thu hriat hi a lungchhiatthlak hle tih kan hria. Mahse, nangmah chauh i ni lo tih hriat reng a pawimawh.. I fa enkawltu team zawng zawng, doctor leh nurse te pawhin he hun harsa tak karah hian nang leh i chhungte tanpui turin an awm a ni. Rhabdoid tumor enkawlna tur a awm a, i fa tan pawh beiseina a awm bawk . Nu leh pa emaw chhungkaw tan cancer support group-a tel tur chungchangah i fa doctor nen inbiakna nei rawh. I chanchin sawiin, midangte tawn hriatte i hriat hian thlamuanna leh fuihna nasa tak i hmu thei a ni.