Tunah hian ' Stem Cell ' tih thumal hi i hre fo tawh ngei ang, a dik em? Ṭhenkhat chuan hei hi natna tam tak, thilmak tihdamna thar ber a ni an ti. A chang chuan chanchinbuah te, TV-ah te pawh sawi a ni. Chuti a nih chuan he stem cell enkawlna hi eng nge ni tak tak? Tunah hian hengte hi mi chungah hman a ni em? Hemi chungchang hi awlsam tak leh chiang takin sawi ila.
A awlsam zawngin, stem cell chu eng nge ni?
Stem cells hi kan taksaa ‘master’ cells angin han ngaihtuah teh. Hna pek hmaa hna enkawltu boss ang bawkin. Heng cell te hian taksa chhunga cell chi hrang hrang (entir nan, heart muscle cells, brain nerve cells , skin cells , liver cells) an nih theihna mak tak an nei a. Hetiang theihna avang hian scientist-te chuan tissue chhia siam that nan emaw, natnain a tihchhiat cell thlak nan cell thar siam nan emaw an hmang thei niin an ngai.
Tunah hian khawvel hmun hrang hrangah he thupui chungchangah hian clinical trial lian tak tak neih mek a ni. Mahse hriat reng tur pawimawh ber chu he zirchianna tam zawk hi a la hmasa ber a ni . Chu chu, enkawlna chu eng angin nge a hlawk tih kan hmuh hmain, mi hnêna pêk a him leh him loh kan hriat hmasak phawt a ngai tihna a ni . A chhan chu damdawi lamah chuan himna hi a pawimawh ber fo a ni.
Stem cell zirchianna kawngah hian eng thil nge a pawimawh ber?
Tunah hian natna leh dinhmun lian tham 11 tana stem cell zirchianna hi ngaih pawimawh a ni hle. Anmahni pakhat zel hi chipchiar takin han thlir ila.
| Dinhmun | Tuna Research dinhmun |
|---|---|
| 1. Lung natna | A tir lamah chuan thinlung tissue chhia siamthat leh thisen kalna kawng thar siam tum a ni. |
| 2. Mit natna | Condition thenkhat (corneal disease) hian hlawhtlinna a nei thin. Midangte chu research stage-ah an awm mek bawk. |
| 3. Zunthlum natna | Insulin siamtu cell (beta cells) siam thar lehna tur zirchianna kalpui mek a ni. A tir lamah chuan. |
| 4. Stroke a awm thin | Thluak chhiatna siamthat nan nerve cell hman dan tur zirchianna neih mek a ni. |
| 5. Spinal Cord Hliam a awm | Paralyzed te enkawl dan tur zirchianna kalpui mek a ni. Hlawhtlinna finfiah a la awm lo. |
| 6. Parkinson natna | Zirna tenau tak tak tlemte chauh kalpui mek a ni. Results sawi tur a la hma lutuk. |
| 7. Alzheimer natna | Mihring hmanga zirchianna chu a la tan lo. Mice hmangin zirchianna an nei tawh bawk. |
| 8. ALS natna (ALS) . | Hriselna a awm theih nan basic research neih mek a ni. |
| 9. Multiple Sclerosis natna a awm thei | Immune system siam thar lehna tur hian stem cell transplantation hi zirchian mek a ni. |
| 10. Cancer natna a ni | Thisen cancer chi hrang hrang (leukemia) tan standard treatment atan hman a ni. Brain cancer chungchangah research phase-ah a awm mek a ni. |
| 11. Cartilage siamthat dan tur | Joint-a cartilage siam thar lehna tur zirchianna neih mek a ni. Results a inthlau hle. |
1. Lung natna
A tum ber pahnih chu heart attack avanga heart tissue chhia siamthat leh thisen kalna kawng thar siam hi a ni . Zirna thenkhatah chuan damlo ngei pawh ruhro (bone marrow) a niBone marrow atanga lak chhuah stem cells chu thinlungah an inject chuan heart attack avanga hliam awmte chu tihdam theihna chhinchhiahna an nei a ni Hei bakah hian mi thenkhat chuan thinlung hnathawh danah hmasawnna engemaw zat an hmu bawk. Mahse hei hi zirchianna hmasa ber a la ni tih hriat reng a pawimawh .
2. Mit natna
UK-a zirchianna pakhatah chuan mit (cornea) pawn lam kil atanga lak chhuah stem cell chi khat bik (limbal stem cells) thlak danglam chuan mit natna avanga mitdel tawhte mit hmuhna a siam tha leh thei tih a tarlang. Chutiang bawkin, mihring embryo (embryonic stem cells) atanga lak chhuah stem cell hmanga macular degeneration ang chi condition atana zirchianna pawh a tir lamah hlawhtlinna a awm tih hmuhchhuah a ni bawk.
3. Zunthlum (Type 1 Diabetes) .
Type 1 diabetes-ah chuan taksa immune system hian pancreas-a insulin siamtu beta cells te chu a tichhia a ni. Chuvangin heng beta cells te hi stem cells hmanga siam thar theih a nih chuan nitin insulin injection lak ngai lohna atangin mi a chhuah zalen thei ang. Hemi nena inzawm zirchiannaah chuan zunthlum vei naupang 15 te chu damlote stem cell hmangin kum 1.5 vel insulin-free-in an kal thei a ni. But since this is a very small study , thutlukna lian tak siam theih a ni lo.
4. Stroke a awm thin
Paralysis chu thluaka thisen kal loh vanga thluak cell thihna a ni . Chuvangin, he thluak tissue chhia hi stem cells hmanga siam that theih a nih leh nih loh zirchian mek a ni. Scotland rama zirchianna an neihah chuan nausen neural stem cells (`fetal neural stem cells`) chu paralyzed damlote thluak ah an inject a. Hetah hian kan ngaih pawimawh ber chu himna lam a ni . Chumi kawngah chuan enkawlna chu a him tih hmuhchhuah a ni. Mahse, eng chen nge a natna lanchhuahna a lo ṭhat tawh tih erawh sawi theih a la ni lo.
Heng enkawlna tam tak hi zirchianna stage-ah a la awm tih hre reng ang che. An himna leh an thatna hi 100% in finfiah a la ni lo.
5. Spinal Cord Hliam a awm
Spinal cord hliam, stem cell hmanga paralyze nei tawhte enkawl hi ngaihven a hlawh hle. Damlote thisen aṭanga lak chhuah stem cells luhtir lehna kawnga zirchiannaah chuan hmasawnna engemaw chen hmu mah se, hlawhtlinna nghet tak, hun rei tak chhunga awm thei chu a la awm lo .
6. Parkinson & Alzheimer natna vei te
Parkinson natna chungchangah hian zirchianna tenau tak tak neih mek a ni a, mahse a result chungchang sawi erawh a la hma lutuk. Alzheimer natna chungchang erawh chuan mihring enchhinna pawh a la intan lo.
7. Hriselna lama natna hrik (MS) .
Hei hi immune system a malfunction avanga lo awm natna a ni bawk. Heta tih tur chu damdawi hmanga damlo taksa chakna (immune system) tihtawp vek a ni a, chutah chuan damlo ruhro atanga lak chhuah stem cells te chu taksaah luhtir leh a, immune system hrisel ‘thar’ siam a ni. Hei hian hlawhtlinna engemaw zat a lantir tawh nachungin, immune system tihtawp vek chu risky tak a ni , chuvangin he enkawlna hi pek hmain ngaihtuahna tam tak neih a ngai a ni.
8. Cancer natna a ni
Damdawi lama stem cell therapy hi standard treatment atana hlawhtling taka hman a nih tawhna hmun pakhat chu thisen cancer, leukemia ang chi te hi a ni. Kan hriat zawng zawng ‘bone marrow transplant’ hi a takah chuan stem cell transplant a ni.
Hei bakah hian thluak cancer chi khat na tak `Glioblastoma` tih chu stem cells hmanga enkawl mek a ni bawk. Hetah hian genetically modified stem cells hmangin cancer cells ah kal in cancer dona damdawi pakhat activate an ni. Hei pawh hi research stage-ah a la awm a ni.
9. Cartilage siamthat dan tur
Stem cells hi khup leh ke ruh ang chi ruhkawr (worn-out cartilage) siam that nan hman theih a nih leh nih loh enfiah mek a ni. Damlo ruhro atanga stem cell lakchhuah te chu gel nen an pawlh a, chutah chuan a chhiatna hmunah an dah leh thin. Mahse result erawh a inthlau hle. A chang chuan cartilage thar lo piang chu a chak tur angin a chak lo va, chu chu harsatna a ni tawh.
Take-Home Thuchah a ni
- Stem cells hi medical field a ni a, theihna sang tak nei mahse a la thang zel a ni. Thilmak tih theihna a nei a, mahse a la awm lo.
- Tuna clinical trial tam zawk hi a tir lamah a ni a, a hlawhtlinna lam ni lovin, a himna lam ngaihtuah a ni.
- Stem cell enkawlna hi natna thenkhat (e.g., thisen cancer, leukemia, leh mit natna thenkhat) tan hlawhtling takin an hmang tawh a ni.
- Mahse mi tam takin an sawi thin natna, thinlung natna, zunthlum, leh Parkinson’s ang chite tan chuan hengte hi zirchianna stage-ah a la awm reng a ni .
- Finfiah loh, license nei lo stem cell enkawlna hmanga bum ngai suh. Eng thil pawh i doctor nen inbia la, thutlukna dik tak siam rawh.
Stem Cell, Stem Cell, Clinical Trial, Lung natna, Zunthlum, Cancer, Stroke, Parkinson’s, Alzheimer’s, Damdawi lam zirchianna
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