Allergy nei fo thin i ni em? Thâwk rimtui tak i lak hnuah i hrual ṭan em, chaw ei hnuah vun i nei ṭan em, a nih loh leh a chang chuan i taksa i hrual mai mai em? Vawiin hian heng zawng zawng hnung lama sipai tenau tak, mahse pawimawh tak mai chungchang kan sawi dawn a ni. I thisen report pakhatah, chu chu ‘Full Blood Count’-ah ‘Basophils’ tih thumal hi i hmu tawh mai thei. Chuti a nih chuan, heng basophils te hi eng nge ni ? Engvangin nge kan taksa hian a mamawh? Hemi chungchang hi a awlsam, hriatthiam awlsam takin i sawi dawn nia.
Basophil chu eng nge ni tak tak?
A awlsam zawngin sawi ila, basophils hi kan thisena thisen var (`White Blood Cell` - WBC) chi khat a ni. Kan taksa hi ram ang maiin han ngaihtuah teh. Tichuan thisen var (white blood cells) hi he ram defence force a ni. He chaknaah hian chakna hrang hrang a awm a. Chuvangin, thisen var hi chi nga a awm a. Basophils hi chi panga zingah hian a tlem ber a, chu chu chakna tlemte chauh an ni tihna a ni.
Heng basophil cell chhungah hian granule te tak te te a awm a. Heng granules te hi chemical pawimawh tak histamine an tih hian a khat a ni. He histamine hian allergy i neih chuan i hmui a ti na a, i mit a sen a, a hnar a chhuak bawk. Basophils hian kan taksa hi parasites lakah a venghim a , hliam a tidam bawk .
Basophils te nihna leh an nihna
Heng basophils property te hi doctor te tan chuan natna thenkhat hriatchhuah nan a pawimawh hle. He sipai te tak te chungchang hi i han en teh ang.
| Hnamhnawih | Hrilhfiahna |
|---|---|
| Lenzawng tehna | Chungte chu a te hle a, micrometer 5-10 (μm) vel a lian a ni. |
| A lan dan leh a rawng | Dye bik (Wright-Giemsa stain) an hnawih chuan heng cell chhunga histamine-a khat granules te hi dark purple angin a lang. Chungte chu awlsam takin microscope hmangin hriat theih a ni. |
| Cell lairil (Nucleus) a ni. | Cell lairil chu ‘S’ letter ang maia siam a ni tlangpui. |
| Nun rei zawng leh pianpui | Basophils hi kan ruh chhunga ruhro (bone marrow) ah a lo piang chhuak thin a. Chutah chuan vawi khat an lo piang tawh a, thisenah an luh hnu darkar 60 vel chauh an dam thin. |
| Surface Markers te pawh a awm | Heng cell chunglama protein bik thenkhat (`CD-123`, `CD-193`) te hian doctor te chu thisen cancer thenkhat (`Leukemia`) ang chi natna te hriatchhuah nan a pui thin. |
Basophils hian kan taksa tan eng rawngbawlna nge an pek?
Basophils hnathawh ber chu a hmaa kan sawi tawh histamine tihchhuah hi a ni. Mahse, chu bâkah, heng cell tê tête hian kan taksa tân rawngbâwlna ropui tak an thawk a ni.
- Allergens laka invenna : Leivut leh pollen ang chi thil taksaa a luh chuan a dodal thin.
- Parasites do dan: Hengte hi parasitic infection pinworms te a awm laiin an thawk chhuak thin.
- Hliam damna : Hliam damna kawngah a pui thin.
- Thisen zam venna : Heng cell te hian heparin an tih chemical an tichhuak bawk a, chu chuan thisen zam duh loh chu a tithianghlim thei a ni.
Allergy leh basophils inzawmna
I kut chu rulhut pakhatin a seh lai han mitthla teh. Hun engemaw chen hnuah a hmun chu a sen a, a hring a, a hnim nasa hle bawk a ni lawm ni? Chu chu basophils atanga chhuak histamine hian a ti a ni.
Histamine hian a tih chu chu hmuna thisen kal a tipung a ni. Chu chuan chu hmunah chuan thisen tam zawk a rawn keng tel a, "a silfai" a, allergen chu a paih chhuak thei a ni. He swelling leh inflammation hi a takah chuan damna kawngah a tel ve a ni.
Allergy nei mi taksaah allergen a luh chuan immune system chuan antibody chi khat Immunoglobulin E (IgE) a siam a. He IgE hi a kal a, allergen ah a inzawm ta a ni. Tichuan basophils te chu an lo kal a, he IgE-allergen complex hi an rawn bei a, an chhunga histamine awm zawng zawng chu an chhuah vek a ni. Chutah chuan allergy symptoms i hmu thin.
- Hnar luang, thawk hah
- Mit sen, a hring chhuak
- Itchy throat a awm
- Vun a hring, a hring
- Asthma vei te thawk harsatna
Engtin nge i thisenah basophil level i check thin?
I doctor-in `Complete Blood Count (CBC)` test, emaw, kan tih angin, `full blood count` tih emaw a tih chuan, chu report-ah chuan basophil count pawh a inziak ang. Hei hi report-ah hian kawng hnihin a tel thei a ni.
1. Za zela (%) angin: Thisen var zawng zawng zinga za zela engzat nge basophils an nih? A tlangpuiin hei hi a value tlem hle a, 0.5% - 1% vel a ni.
2. Absolute Count: Thisen milliliter khata basophils awm zat tak tak.
A pawimawh ber chu i value te chu i lab report-a ‘Normal Range’ emaw ‘Reference Range’ column nen khaikhin la, heng normal value te hi lab tina machine hman dan azirin a danglam deuh thei a ni.
| Tlukpui | Awmzia |
|---|---|
| Normal Count a ni | Thisen var 0.5% - 2% inkar a ni. Absolute value hi 0.01 x 109/L atanga 0.08 x 109/L thleng a ni thei tlangpui. |
| Level sang zawk (Basophilia) . | Basophil level hi a pangngai aia sang a ni. |
| A hniam lam (Basopenia) . | Basophil level chu a tlangpui aia tlahniam. |
Basophils (basophilia) pung hi a hlauhawm em?
Basophil level sang hi damdawi lam chuan ``Basophilia'' tia hriat a ni a, hei hi chhan hrang hrang a awm thei.
- Allergy: Ei leh in, damdawi, leivut, etc. allergy nei.
- Infection: Infection thenkhat chickenpox leh influenza ang chi te.
- Thyroid lama harsatna: Thyroid hormone hniam (`Hypothyroidism`).
- Vun natna: Eczema ang chi vun natna, atopic dermatitis ang chi.
- Thisen natna: Polycythemia vera ang chi natna.
- Cancer natna thenkhat: Thisen cancer, chronic myeloid leukemia (CML) ang chi te.
He list hian hlauthawng suh. A tam zawkah chuan basophil count sang deuh hi allergy pangngai ang chi thil awlsam vang a ni thei. Mahse a chhan dik tak chu i doctor kutah i dah tur a ni. A chhan finfiah nan a tul chuan test dang a nei leh ang.
Basopenia chu eng nge ni?
Basophil level tlahniam hi ``Basopenia`` an ti a, hei hi ``Basophilia'' aiin a tlem zawk a ni.`` Hei hi chhan hrang hrang vang pawh a ni thei bawk.
- Infection thenkhat.
- Thyroid hormone siam chhuah tam lutuk (`Hyperthyroidism`).
- Allergy na tak, a rang thei ang bera awm (`Anaphylaxis`).
- Immune system natna thenkhat, entirnan `Systemic Lupus Erythematosus (SLE)`.
Basophils tlahniam hian kan taksa hliam dam danah nghawng a nei thei bawk.
Damdawi lam thurawn lak nghal tur
Allergy pangngai hi hlauhawm lo mahse, a chang chuan immune system hian a overreact thei bawk. Hei hi `Anaphylaxis` an ti a.
Anaphylaxis hi nunna atana hlauhawm medical emergency a ni. Nangmah emaw midang emaw hian a hnuaia symptoms te hi i neih chuan hospital emergency department (ETU) hnai ber pan nghal rawh.
- Ka hmui, lei emaw, hmai emaw a hring chhuak
- Thâwk harsa
- Chaw ei harsat
- Taksa zawng zawngah vun rawng emaw sen emaw a awm
- Pum na, luak chhuak emaw, luak chhuak emaw
- Chest tightness emaw, whistling ri emaw
- Luak chhuak emaw, muhil emaw tih hriat
Hetiang hunah hian hlauthawng lova, damdawi lam pan vat a pawimawh hle.
Take-Home Thuchah a ni
- Basophils hi kan immune system-a thisen var chi pawimawh tak a ni a, allergy leh parasitic infection te a do thei a ni.
- An tihchhuah histamine hi allergy symptom tam tak, itching leh swelling te thlentu a ni.
- I thisen report-a i basophil level chu a pangngai aia pawn a nih chuan hlauthawng suh la, i doctor nen inbia ang che. Vawi tam tak chu a chhan chu thil awlsam tak a ni thei.
- Allergy symptom na tak tak, thawk harsa leh hmai vun natna i neih chuan emergency a ni. Damdawi in pakhat Emergency Department (ETU) ah kal nghal rawh.
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